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resting-state functional magnetic resonance imaging

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https://www.readbyqxmd.com/read/29340793/neuroimaging-findings-in-patients-with-medication-overuse-headache
#1
REVIEW
Tzu-Hsien Lai, Shuu-Jiun Wang
Medication overuse headache (MOH) is a secondary headache syndrome defined as the deterioration of the headache associated with the overuse of analgesics. The prevalence of MOH is 1-2% in the general population and even up to 50% in special clinics. Overuse of abortive medications is highly associated with chronic daily headaches and also a known risk factor for headache evolution. Possible mechanisms include neural plasticity changes such as sensitization and defective endogenous pain inhibition. Psychological studies have suggested dependence, even addiction, in patients with MOH...
January 16, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29339474/robust-prediction-of-individual-creative-ability-from-brain-functional-connectivity
#2
Roger E Beaty, Yoed N Kenett, Alexander P Christensen, Monica D Rosenberg, Mathias Benedek, Qunlin Chen, Andreas Fink, Jiang Qiu, Thomas R Kwapil, Michael J Kane, Paul J Silvia
People's ability to think creatively is a primary means of technological and cultural progress, yet the neural architecture of the highly creative brain remains largely undefined. Here, we employed a recently developed method in functional brain imaging analysis-connectome-based predictive modeling-to identify a brain network associated with high-creative ability, using functional magnetic resonance imaging (fMRI) data acquired from 163 participants engaged in a classic divergent thinking task. At the behavioral level, we found a strong correlation between creative thinking ability and self-reported creative behavior and accomplishment in the arts and sciences (r = 0...
January 16, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29339315/insulin-sensitivity-predicts-brain-network-connectivity-following-a-meal
#3
John P Ryan, Helmet T Karim, Howard J Aizenstein, Nicole L Helbling, Frederico G S Toledo
There is converging evidence that insulin plays a role in food-reward signaling in the brain and has effects on enhancing cognition. Little is known about how these effects are altered in individuals with insulin resistance. The present study was designed to identify the relationships between insulin resistance and functional brain connectivity following a meal. Eighteen healthy adults (7 male, 11 female, age: 41-57 years-old) completed a frequently-sampled intravenous glucose tolerance test to quantify insulin resistance...
January 12, 2018: NeuroImage
https://www.readbyqxmd.com/read/29325327/-resting-state-network-evaluation-of-chronic-smokers-by-functional-magnetic-resonance-imaging
#4
Y Zhang, Y L Li, J L Cheng, A K Dong, K Xu, Y L Li
Objective: To explore the neuromechanism of nicotine smoking, we use independent component analysis (ICA) of resting-state functional magnetic resonance imaging (fMRI) to investigate the differences of functional connectivity of resting-state networks (RSN) in chronic smokers. Methods: Forty-five chronic smokers and thirty-four age and gender matched normal nonsmoking controls experienced resting-state fMRI scanning in 3.0T MRI scanner.Differences of the function connection in each RSN between chronic smokers group and nonsmoking controls group were analyzed by SPM software which was based on Matlab platform...
December 19, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29323046/non-concomitant-cortical-structural-and-functional-alterations-in-sensorimotor-areas-following-incomplete-spinal-cord-injury
#5
Yu Pan, Wei-Bei Dou, Yue-Heng Wang, Hui-Wen Luo, Yun-Xiang Ge, Shu-Yu Yan, Quan Xu, Yuan-Yuan Tu, Yan-Qing Xiao, Qiong Wu, Zhuo-Zhao Zheng, Hong-Liang Zhao
Brain plasticity, including anatomical changes and functional reorganization, is the physiological basis of functional recovery after spinal cord injury (SCI). The correlation between brain anatomical changes and functional reorganization after SCI is unclear. This study aimed to explore whether alterations of cortical structure and network function are concomitant in sensorimotor areas after incomplete SCI. Eighteen patients with incomplete SCI (mean age 40.94 ± 14.10 years old; male:female, 7:11) and 18 healthy subjects (37...
December 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29322586/functional-connectivity-predicts-gender-evidence-for-gender-differences-in-resting-brain-connectivity
#6
Chao Zhang, Chase C Dougherty, Stefi A Baum, Tonya White, Andrew M Michael
Prevalence of certain forms of psychopathology, such as autism and depression, differs between genders and understanding gender differences of the neurotypical brain may provide insights into risk and protective factors. In recent research, resting state functional magnetic resonance imaging (rfMRI) is widely used to map the inherent functional networks of the brain. Although previous studies have reported gender differences in rfMRI, the robustness of gender differences is not well characterized. In this study, we use a large data set to test whether rfMRI functional connectivity (FC) can be used to predict gender and identify FC features that are most predictive of gender...
January 10, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29318488/disrupted-topological-organization-of-the-frontal-mesolimbic-network-in-obese-patients
#7
Qianqian Meng, Yu Han, Gang Ji, Guanya Li, Yang Hu, Li Liu, Qingchao Jin, Karen M von Deneen, Jizheng Zhao, Guangbin Cui, Huaning Wang, Dardo Tomasi, Nora D Volkow, Jixin Liu, Yongzhan Nie, Yi Zhang, Gene-Jack Wang
Neuroimaging studies have revealed brain functional abnormalities in frontal-mesolimbic regions in obesity. However, the effects of obesity on brain network topology remains largely unknown. In the current study, we employed resting-state functional magnetic resonance imaging and graph theory methods to investigate obesity-related changes in brain network topology in 26 obese patients and 28 normal weight subjects. Results revealed that the whole-brain networks of the two groups exhibited typical features of small-world topology...
January 9, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29316519/the-regional-homogeneity-of-cingulate-precuneus-regions-the-putative-biomarker-for-depression-and-anxiety
#8
Chien-Han Lai
OBJECTIVES: In addition to clinical interview, the modern putative biomarker to differentiate depression and anxiety would be warranted. The translational medicine characteristics of neuroimaging, such as the regional homogeneity (ReHo), is an option for depression and anxiety. Therefore we designed this study trying to identify the biomarker pattern for depression and anxiety. METHODS: Resting-state functional magnetic resonance imaging was acquired for 53 patients with first-episode medicine-naïve major depressive disorder (MDD), 53 first-episode medicine-naïve patients with panic disorder (PD) and 54 controls...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29315951/four-way-multimodal-fusion-of-7%C3%A2-t-imaging-data-using-an-mcca-jica-model-in-first-episode-schizophrenia
#9
Kristin K Lottman, David M White, Nina V Kraguljac, Meredith A Reid, Vince D Calhoun, Fabio Catao, Adrienne C Lahti
Acquisition of multimodal brain imaging data for the same subject has become more common leading to a growing interest in determining the intermodal relationships between imaging modalities to further elucidate the pathophysiology of schizophrenia. Multimodal data have previously been individually analyzed and subsequently integrated; however, these analysis techniques lack the ability to examine true modality inter-relationships. The utilization of a multiset canonical correlation and joint independent component analysis (mCCA + jICA) model for data fusion allows shared or distinct abnormalities between modalities to be examined...
January 9, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29310446/resting-state-fmri-in-primary-sj%C3%A3-gren-syndrome
#10
Wu Xing, Wei Shi, Yueshuang Leng, Xianting Sun, Tingting Guan, Weihua Liao, Xiaoyi Wang
Background The involvement of the central nervous system in primary Sjögren syndrome (pSS) remains controversial. Functional magnetic resonance imaging (fMRI) is a relatively new method that can be applied to investigate the heterogeneity of central nervous system (CNS) involvement in pSS patients through regional homogeneity (ReHo) analysis. Purpose To collect data from pSS patients and healthy controls, and use ReHo analysis to elucidate the neurobiological mechanism of CNS involvement in pSS. Material and Methods Fourteen clinically diagnosed pSS patients and 14 age- and gender-matched healthy controls underwent resting-state fMRI...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29305627/antagonism-at-the-nr2b-subunit-of-nmda-receptors-induces-increased-connectivity-of-the-prefrontal-and-subcortical-regions-regulating-reward-behavior
#11
Natalia Gass, Robert Becker, Markus Sack, Adam J Schwarz, Jonathan Reinwald, Alejandro Cosa-Linan, Lei Zheng, Christian Clemm von Hohenberg, Dragos Inta, Andreas Meyer-Lindenberg, Wolfgang Weber-Fahr, Peter Gass, Alexander Sartorius
RATIONALE: Evidence indicates that ketamine's rapid antidepressant efficacy likely results from its antagonism of NR2B-subunit-containing NMDA receptors (NMDAR). Since ketamine equally blocks NR2A- and NR2B-containing NMDAR, and has affinity to other receptors, NR2B-selective drugs might have improved therapeutic efficiency and side effect profile. OBJECTIVES: We aimed to compare the effects of (S)-ketamine and two different types of NR2B-selective antagonists on functional brain networks in rats, in order to find common circuits, where their effects intersect, and that might explain their antidepressant action...
January 5, 2018: Psychopharmacology
https://www.readbyqxmd.com/read/29304099/functional-magnetic-resonance-imaging-reveals-differences-in-brain-activation-in-response-to-thermal-stimuli-in-diabetic-patients-with-and-without-diabetic-peripheral-neuropathy
#12
Juan Li, Wanying Zhang, Xia Wang, Tangmi Yuan, Peiyao Liu, Tao Wang, Le Shen, Yuguang Huang, Naishi Li, Hui You, Tixian Xiao, Feng Feng, Chao Ma
INTRODUCTION: Diabetes affects both the peripheral and central nervous systems. The aim of this study was to explore the changes in brain activity in response to thermal stimuli in diabetic patients with and without diabetic peripheral neuropathy (DPN) using functional magnetic resonance imaging (fMRI). METHODS: A total of 36 right-handed volunteers were enrolled: eight patients with Type-2 diabetes mellitus and DPN, 13 patients with Type-2 diabetes mellitus lacking DPN (NDPN patients), and 15 healthy volunteers (HV)...
2018: PloS One
https://www.readbyqxmd.com/read/29304050/severe-hyposmia-and-aberrant-functional-connectivity-in-cognitively-normal-parkinson-s-disease
#13
Noritaka Yoneyama, Hirohisa Watanabe, Kazuya Kawabata, Epifanio Bagarinao, Kazuhiro Hara, Takashi Tsuboi, Yasuhiro Tanaka, Reiko Ohdake, Kazunori Imai, Michihito Masuda, Tatsuya Hattori, Mizuki Ito, Naoki Atsuta, Tomohiko Nakamura, Masaaki Hirayama, Satoshi Maesawa, Masahisa Katsuno, Gen Sobue
OBJECTIVE: Severe hyposmia is a risk factor of dementia in Parkinson's disease (PD), while the underlying functional connectivity (FC) and brain volume alterations in PD patients with severe hyposmia (PD-SH) are unclear. METHODS: We examined voxel-based morphometric and resting state functional magnetic resonance imaging findings in 15 cognitively normal PD-SH, 15 cognitively normal patients with PD with no/mild hyposmia (PD-N/MH), and 15 healthy controls (HCs)...
2018: PloS One
https://www.readbyqxmd.com/read/29297154/altered-topological-patterns-of-brain-functional-networks-in-crohn-s-disease
#14
Peng Liu, Ru Li, Chunhui Bao, Ying Wei, Yingying Fan, Yanfei Liu, Geliang Wang, Huangan Wu, Wei Qin
Crohn's disease (CD) has been reported to relate with the functional and structural alterations in several local brain regions. However, it remains unknown whether the possible abnormalities of information transmission and integration between brain regions are associated with CD. The purpose of this study was to investigate the topological alterations of brain functional networks and the potential relationships between the neuroimaging findings and CD clinical characteristics. 43 remissive CD patients and 37 matched healthy controls (HCs) were recruited to obtain their resting-state functional magnetic resonance imaging (fMRI) data...
January 3, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29297053/anatomical-wiring-and-functional-networking-changes-in-the-visual-system-following-optic-neuritis
#15
Yael Backner, Joseph Kuchling, Said Massarwa, Timm Oberwahrenbrock, Carsten Finke, Judith Bellmann-Strobl, Klemens Ruprecht, Alexander U Brandt, Hanna Zimmermann, Noa Raz, Friedemann Paul, Netta Levin
Importance: Clinical outcome in multiple sclerosis was suggested to be driven by not only remyelination but also adaptive reorganization. This mechanism needs to be further understood. Objective: To explore anatomical and functional visual networks in patients with optic neuritis (ON) to assess the relative weight of each connectivity modality to expedite visual recovery. Design, Setting, and Participants: Between March 11, 2011, and May 26, 2014, 39 patients with either clinically isolated syndrome (CIS) ON (n = 18) or other CIS (non-ON) (n = 21) were recruited 1 to 28 months following an initial clinical event...
January 2, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29297041/association-of-visual-impairment-in-neuromyelitis-optica-spectrum-disorder-with-visual-network-reorganization
#16
Carsten Finke, Hanna Zimmermann, Florence Pache, Frederike C Oertel, Velina Sevdalinova Chavarro, Yelyzaveta Kramarenko, Judith Bellmann-Strobl, Klemens Ruprecht, Alexander U Brandt, Friedemann Paul
Importance: Severe visual impairment is one of the major symptoms in neuromyelitis optica spectrum disorder (NMOSD), but functional network reorganization induced by the diminished sensory input has not been investigated thus far. Objective: To examine adaptive visual network connectivity changes in NMOSD. Design, Setting, and Participants: In this cross-sectional study, data were collected from May 1, 2013, through February 31, 2016, from 31 patients with aquaporin-4 antibody-positive NMOSD and 31 age- and sex-matched healthy control individuals at the Department of Neurology and NeuroCure Clinical Research Center at Charité-Universitätsmedizin Berlin, Berlin, Germany...
January 2, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29288107/memory-deficits-after-aneurysmal-subarachnoid-hemorrhage-an-fmri-study
#17
Jiabin Su, Tongzhou E, Qihao Guo, Yu Lei, Yuxiang Gu
BACKGROUND: Patients suffer from aneurysmal subarachnoid hemorrhage (aSAH) are thought to have cognitive impairment. However, little is known about characteristics of functional imaging in aSAH patients OBJECTIVE: To explore the whole brain activity pattern in aSAH patients using amplitude of low-frequency fluctuation (ALFF) and functional connectivity (FC). METHOD: 50 aSAH patients and 30 healthy controls were recruited and subjected to a resting-state functional magnetic resonance imaging scan and cognitive tasks...
December 26, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29278773/an-evaluation-of-the-efficacy-reliability-and-sensitivity-of-motion-correction-strategies-for-resting-state-functional-mri
#18
Linden Parkes, Ben Fulcher, Murat Yu Cel, Alex Fornitod
Estimates of functional connectivity derived from resting-state functional magnetic resonance imaging (rs-fMRI) are sensitive to artefacts caused by in-scanner head motion. This susceptibility has motivated the development of numerous denoising methods designed to mitigate motion-related artefacts. Here, we compare popular retrospective rs-fMRI denoising methods, such as regression of head motion parameters and mean white matter (WM) and cerebrospinal fluid (CSF) (with and without expansion terms), aCompCor, volume censoring (e...
December 23, 2017: NeuroImage
https://www.readbyqxmd.com/read/29275591/-dysfunctional-resting-state-connectivity-of-default-mode-network-in-adolescent-patients-with-first-episode-drug-naive-major-depressive-disorder
#19
S Y Li, Y Zhu, Y L Wang, P P Lü, W B Zuo, F Y Li
Objective: To study resting-state functional connectivity (FC) of default mode network (DMN) in adolescent patients with first-episode drug-naive major depressive disorder (MDD). Methods: We enrolled thirty first-episode and drug-naive adolescent MDD patients and twenty-nine adolescent healthy control (HC) participants in the First Affiliated Hospital of Zhengzhou University. There were no differences in age, sex, and education between the MDD and HC group. Resting-state functional magnetic resonance images (fMRI) was performed...
December 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29275589/-characteristics-of-cognitive-impairment-and-the-resting-state-functional-mri-in-patients-with-leukoaraiosis
#20
Q Li, L Q Zhao, F Y Hu
Objective: To investigate the features of cognitive impairment and potential physiopathologic mechanism using neuropsychological assessment and resting state functional magnetic resonance imaging (rs-fMRI) in patients with leukoaraiosis (LA). Methods: A total of 13 patients with LA (LA group) and 13 healthy controls (NC group) from Shanxi Provincial People's Hospital between January and June 2016 were recruited. The two groups were matched for age, sex, education, and vascular risk factors. All the subjects underwent neuropsychological assessment and the scan of rs-fMRI...
December 5, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
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