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https://www.readbyqxmd.com/read/29779141/socioeconomic-factors-and-individual-lifestyles-influencing-the-incidence-of-patella-fractures-a-national-population-based-survey-in-china
#1
Yanbin Zhu, Song Liu, Wei Chen, Lin Wang, Xiaolin Zhang, Yingze Zhang
BACKGROUND: We aimed to do a national survey on the population-based incidence of patella fractures and related risk factors fracture in China. METHODS: All the data on patella fractures were available from the China National Fracture Survey (CNFS) between January and May in 2015. And in the CNFS, all eligible household members were selected from 24 urban cities and 24 rural counties of eight provinces of China, with stratified random sampling and the probability proportional to size method used...
May 19, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29779060/three-way-dna-junction-based-platform-for-ultra-sensitive-fluorometric-detection-of-multiple-metal-ions-as-exemplified-for-cu-ii-mg-ii-and-pb-ii
#2
Wen Yun, Xiaoqing Du, Junsheng Liao, Ge Sang, Lin Chen, Ning Li, Lizhu Yang
A DNA-based fluorometric method is described for simultaneous determination of multiple metal ions. It is based on recycling cleavage of hairpins by using a three-way DNA junction structure. Three DNA sequences containing a binding region and an enzyme-strand (E-DNA) region are hybridized to form a three-way DNA junction. The enzyme strand regions at the end of the DNA sequence binds to the substrate sequence (S-DNA) at the loop of the hairpin to form typical DNAzyme structures. In the presence of analyte metal ions, the DNAzyme structure thus formed cleaves the loop of hairpins...
May 20, 2018: Mikrochimica Acta
https://www.readbyqxmd.com/read/29779021/the-level-of-monocyte-chemoattractant-protein-1-may-be-affected-by-several-factors
#3
Mustafa Gulgun
No Abstract.
May 20, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29778737/cancer-immunotherapy-efficacy-and-patients-sex-a-systematic-review-and-meta-analysis
#4
Fabio Conforti, Laura Pala, Vincenzo Bagnardi, Tommaso De Pas, Marco Martinetti, Giuseppe Viale, Richard D Gelber, Aron Goldhirsch
BACKGROUND: Despite the acknowledged sex-related dimorphism in immune system response, little is known about the effect of patients' sex on the efficacy of immune checkpoint inhibitors as cancer treatments. We did a systematic review and meta-analysis to assess the heterogeneity of immune checkpoint inhibitor efficacy between men and women. METHODS: We systematically searched PubMed, MEDLINE, Embase, and Scopus, from database inception to Nov 30, 2017, for randomised controlled trials of immune checkpoint inhibitors (inhibitors of PD-1, CTLA-4, or both) that had available hazard ratios (HRs) for death according to patients' sex...
May 16, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29778452/cognitive-performance-in-young-and-middle-aged-adults-with-migraine-investigating-the-correlation-with-white-matter-hyperintensities-and-psychological-symptoms
#5
Abdulkadir Tunç, Aysel Kaya Tekeşin, Belma Doğan Güngen, Esra Arda
INTRODUCTION: This study aimed to evaluate the cognitive performance of migraine patients with (MwA) and without aura (MwoA) and investigate the correlation of white matter hyperintensities (WMHs) and psychological symptoms with their cognitive test scores. MATERIAL AND METHODS: Hundred migraine patients aged 20-55 years and 80 healthy volunteers with similar age, sex, and education level were enrolled. The total Montreal Cognitive Assessment (MoCA) scores were compared by age, sex, presence of aura, migraine duration, attack frequency, pain localization, presence and number of WMHs, and the scores of the Beck Depression Inventory and the Beck Anxiety Inventory (BAI)...
May 8, 2018: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29777965/what-do-we-know-about-sibling-attended-birth-an-integrative-literature-review
#6
REVIEW
Nora L Naber, Suzanne Miller, Sally A Baddock
OBJECTIVE: to consolidate existing research in the field of sibling attended birth (SAB) into a body of knowledge to inform decision-making processes and guide midwifery practice throughout the sibling attended birth experience. DESIGN: An integrative literature review. DATA SOURCES: CINAHL Complete, Cochrane Library, PubMed, Index New Zealand, Australia/New Zealand Reference Centre, grey literature databases REVIEW METHODS: An extensive search of five electronic databases as well as 17 grey literature databases was conducted...
May 8, 2018: Midwifery
https://www.readbyqxmd.com/read/29777506/an-extended-kalman-filter-for-mouse-tracking
#7
Hongjun Choi, Mingi Kim, Onseok Lee
Animal tracking is an important tool for observing behavior, which is useful in various research areas. Animal specimens can be tracked using dynamic models and observation models that require several types of data. Tracking mouse has several barriers due to the physical characteristics of the mouse, their unpredictable movement, and cluttered environments. Therefore, we propose a reliable method that uses a detection stage and a tracking stage to successfully track mouse. The detection stage detects the surface area of the mouse skin, and the tracking stage implements an extended Kalman filter to estimate the state variables of a nonlinear model...
May 19, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29777504/implementation-and-validation-of-constitutive-relations-for-human-dermis-mechanical-response
#8
Alessandra Aldieri, Mara Terzini, Cristina Bignardi, Elisabetta M Zanetti, Alberto L Audenino
Finite element models in conjunction with adequate constitutive relations are pivotal in several physiological and medical applications related to both native and engineered tissues, allowing to predict the tissue response under various loading states. In order to get reliable results, however, the validation of the constitutive models is crucial. Therefore, the main purpose of this work is to provide an experimental-computational approach to the biomechanical investigation of soft tissues such as the dermis...
May 19, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29777499/correction-to-hrqol-in-diverse-ethnic-groups-with-diabetes-findings-from-the-2014-brfss
#9
Kelley Newlin Lew, Julie Wagner, Omar Braizat
The following corrections to this article as originally published should be noted:In the first sentence of the abstract, "non-Hispanic Whites, non-Hispanic Blacks, and Hispanics adults with diabetes" should read "non-Hispanic White, non-Hispanic Black, and Hispanic adults with diabetes".
May 18, 2018: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29777402/a-national-study-of-the-use-of-asymptomatic-systemic-imaging-for-surveillance-following-breast-cancer-treatment-aft-01
#10
Jessica R Schumacher, Heather B Neuman, George J Chang, Benjamin D Kozower, Stephen B Edge, Menggang Yu, David J Vanness, Yajuan Si, Elizabeth A Jacobs, Amanda B Francescatti, Patricia A Spears, Jeffrey Havlena, Taiwo Adesoye, Daniel McKellar, David Winchester, Elizabeth S Burnside, Caprice C Greenberg
BACKGROUND: Although not guideline recommended, studies suggest 50% of locoregional breast cancer patients undergo systemic imaging during follow-up, prompting its inclusion as a Choosing Wisely measure of potential overuse. Most studies rely on administrative data that cannot delineate scan intent (prompted by signs/symptoms vs. asymptomatic surveillance). This is a critical gap as intent is the only way to distinguish overuse from appropriate care. OBJECTIVE: Our aim was to assess surveillance systemic imaging post-breast cancer treatment in a national sample accounting for scan intent...
May 17, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29777313/gold-nanocluster-based-ratiometric-fluorescent-probes-for-hydrogen-peroxide-and-enzymatic-sensing-of-uric-acid
#11
Dongqin Yang, Minchuan Luo, Junwei Di, Yifeng Tu, Jilin Yan
A method is described for ratiometric fluorometric assays of H2 O2  by using two probes that have distinct response profiles. Under the catalytic action of ferrous ion, the 615 nm emission of protein-stabilized gold nanoclusters (under 365 nm photoexcitation) is quenched by H2 O2 , while an increased signal is generated with a peak at 450 nm by oxidizing coumarin with the H2 O2 /Fe(II) system to form a blue emitting fluorophore. These decrease/increase responses give a ratiometric signal. The ratio of the fluorescences at the two peaks are linearly related to the concentration of H2 O2 in the range from 0...
May 18, 2018: Mikrochimica Acta
https://www.readbyqxmd.com/read/29777309/fluorometric-determination-of-vibrio-parahaemolyticus-using-an-f-0-f-1-atpase-based-aptamer-and-labeled-chromatophores
#12
Nuo Duan, Shijia Wu, Huiling Zhang, Ying Zou, Zhouping Wang
An F0 F1 -ATPase-based aptasensor is described for the fluorometric determination of Vibrio parahaemolyticus. Chromatophores containing F0 F1 -ATPases were first prepared from Rhodospirillum rubrum cells. Then, an aptamer-functionalized chromatophore acts as the capture probe, and a chromatophore labeled with the pH probe fluorescein acts as the signalling probe. In the presence of V. parahaemolyticus, the rotation rate of F0 F1 -ATPase is decreased due to the formation of the aptamer-chromatophore complex...
May 18, 2018: Mikrochimica Acta
https://www.readbyqxmd.com/read/29777269/pediatric-appendicitis-severity-in-kwazulu-natal-south-africa-a-retrospective-cohort-analysis
#13
Matthew C Hernandez, Victor Y Kong, John L Bruce, Johnathon M Aho, Grant L Laing, Martin D Zielinski, Damian L Clarke
BACKGROUND: Acute appendicitis is a common pediatric surgical emergency; however, there are few grading systems to assign disease severity. The American Association for the Surgery of Trauma (AAST) recently developed a grading system for a variety of emergency surgical conditions, including appendicitis. The severity of acute appendicitis in younger patients in KwaZulu-Natal (South Africa) is unknown. We aimed to describe the disease severity in this patient population using the AAST grading system hypothesizing that the AAST grade would correlate with morbidity, management type, and duration of stay...
May 17, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29777265/abstracts-degro-2018
#14
(no author information available yet)
No abstract text is available yet for this article.
May 17, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29777106/clinical-prediction-models-to-support-the-diagnosis-of-asthma-in-primary-care-a-systematic-review-protocol
#15
L Daines, S McLean, A Buelo, S Lewis, A Sheikh, H Pinnock
Substantial over-diagnosis and under-diagnosis of asthma in adults and children has recently been reported. As asthma is mostly diagnosed in non-specialist settings, a clinical prediction model (CPM) to aid the diagnosis of asthma in primary care may help improve diagnostic accuracy. We aim to systematically identify, describe, compare, and synthesise existing CPMs designed to support the diagnosis of asthma in children and adults presenting with symptoms suggestive of the disease, in primary care settings or equivalent populations...
May 18, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29776822/the-effect-of-age-and-sex-on-the-cervical-range-of-motion-a-systematic-review-and-meta-analysis
#16
REVIEW
Fumin Pan, Rizwan Arshad, Thomas Zander, Sandra Reitmaier, Arno Schroll, Hendrik Schmidt
Cervical-flexibility examination is routinely performed in neck-pain patients. However, diagnosis of cervical-flexibility impairment requires physiological reference values, which vary widely among the population. Although there is a general understanding that the cervical range of motion (RoM) alters with age and sex, the consolidated details of these variations remain lacking. A systematic review and meta-analysis was performed to evaluate the difference of cervical RoM in different age and sex populations...
May 7, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29776691/a-voice-patch-system-in-the-primate-brain-for-processing-vocal-information
#17
Pascal Belin, Clémentine Bodin, Virginia Aglieri
We review behavioural and neural evidence for the processing of information contained in conspecific vocalizations (CVs) in three primate species: humans, macaques and marmosets. We focus on abilities that are present and ecologically relevant in all three species: the detection and sensitivity to CVs; and the processing of identity cues in CVs. Current evidence, although fragmentary, supports the notion of a "voice patch system" in the primate brain analogous to the face patch system of visual cortex: a series of discrete, interconnected cortical areas supporting increasingly abstract representations of the vocal input...
May 7, 2018: Hearing Research
https://www.readbyqxmd.com/read/29776573/duration-of-dual-antiplatelet-therapy-and-outcome-in-patients-with-acute-coronary-syndrome-undergoing-percutaneous-revascularization-a-meta-analysis-of-11-randomized-trials
#18
Monica Verdoia, Elvin Khedi, Claudia Ceccon, Harry Suryapranata, Giuseppe De Luca
BACKGROUND: Acute coronary syndromes (ACS) represent a context of higher thrombotic risk, where larger advantages have been achieved by the administration of dual antiplatelet therapy (DAPT). However, the indication of 1 year DAPT after coronary angioplasty for ACS has been supported by an outdated randomized trial (PCI-CURE). In addition, the initial fear of late thrombotic events emerged with first generation drug-eluting stents (DES), that suggested the need of a prolonged DAPT prescription, has been completely overcome by the recent technological evolution of DES, that have shown faster re-endothelization and lower rates of late thrombotic complications...
August 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29776467/how-memory-replay-in-sleep-boosts-creative-problem-solving
#19
REVIEW
Penelope A Lewis, Günther Knoblich, Gina Poe
Creative thought relies on the reorganisation of existing knowledge. Sleep is known to be important for creative thinking, but there is a debate about which sleep stage is most relevant, and why. We address this issue by proposing that rapid eye movement sleep, or 'REM', and non-REM sleep facilitate creativity in different ways. Memory replay mechanisms in non-REM can abstract rules from corpuses of learned information, while replay in REM may promote novel associations. We propose that the iterative interleaving of REM and non-REM across a night boosts the formation of complex knowledge frameworks, and allows these frameworks to be restructured, thus facilitating creative thought...
June 2018: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/29776356/policy-development-and-challenges-of-global-mental-health-a-systematic-review-of-published-studies-of-national-level-mental-health-policies
#20
Wei Zhou, Yu Yu, Mei Yang, Lizhang Chen, Shuiyuan Xiao
BACKGROUND: Mental health policy can be an essential and powerful tool to improve a population's mental health. However, around one third of countries do not possess a mental health policy, and there are large disparities in population coverage rates between high- and low-income countries. The goal of this study is to identify the transition and implementation challenges of mental health policies in both high-income countries (HICs) as well as middle- and low-income countries (MLICs)...
May 18, 2018: BMC Psychiatry
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