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https://www.readbyqxmd.com/read/28448314/a-30-minute-monthly-live-webinar-based-journal-club-activity-alters-the-self-reported-behaviors-of-dermatologic-surgeons
#1
Amy E Zavell, Judah N Greenberg, Murad Alam, Eric S Armbrecht, Ian A Maher
BACKGROUND: Journal clubs provide a way to communicate advances in recent literature. In outpatient surgical subspecialties, such as dermatologic surgery, physicians may face challenges in finding or attending meetings pertinent to their practice. OBJECTIVE: To assess the utility of a live web-based journal club in dermatologic surgery. MATERIALS AND METHODS: Monthly 30-minute journal club sessions covering 5 to 6 scholarly articles. Anonymous surveys were used to evaluate the utility and self-reported learning associated with each meeting...
April 12, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28447111/-diagnostics-and-treatment-of-osteoid-osteoma
#2
REVIEW
P Orth, D Kohn
BACKGROUND: Osteoid osteoma is the third most common benign bone tumor and typically induces pain that is worse at night. OBJECTIVE: To identify the epidemiological, pathogenetic, histological and radiological characteristics of osteoid osteoma and to present the broad variety of treatment options. MATERIAL AND METHODS: This review article summarizes relevant clinical studies and meta-analyses on this topic. RESULTS: Osteoid osteoma is characterized by a central nidus smaller than 1...
April 26, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28441315/an-overview-of-chronic-spinal-pain-revisiting-diagnostic-categories-and-exploring-an-evolving-role-for-neurostimulation
#3
Ashwini Sharan, Jonathan Riley, Christian Hoelscher
STUDY DESIGN: Topic Overview OBJECTIVE.: To describe the varied etiologies resulting in chronic spinal pain and review the current available evidence for treatments. SUMMARY OF BACKGROUND DATA: Chronic pain conditions, especially those that affect the axial back and radiate to the extremities, affect a large population. This results in pronounced disability and a high socioeconomic burden. Our understanding of the underlying mechanisms for chronic pain is limited...
April 24, 2017: Spine
https://www.readbyqxmd.com/read/28441129/medical-school-outreach-and-mentorship-for-rural-secondary-school-students-a-pilot-of-the-southwestern-ontario-medical-mentorship-program
#4
Maija A Robinson, Matt B Douglas-Vail, Jessica N Bryce, Theunis J van Zyl
INTRODUCTION: Rural communities in Canada face challenges with physician recruitment. Physicians from rural backgrounds are more likely to practise in rural areas; however, rural students are underrepresented in medical schools. To address this, the Southwestern Ontario Medical Mentorship Program (SWOMMP) was created to expose rural secondary school students to medical careers. METHODS: This pilot project involved a school-based interactive session run by rural medical students on paths to medicine, medical specialties and skills workshops of roughly 2...
2017: Canadian Journal of Rural Medicine
https://www.readbyqxmd.com/read/28439059/-calcium-and-bone-metabolism-across-women-s-life-stages-nutritive-therapy-for-improvement-of-bone-and-calcium-metabolism-according-to-life-stage-in-women
#5
Kazuya Makita
Postmenopausal osteoporosis is mainly caused by decreased estrogen levels, and progression of disease is associated with irreversible changes. It is therefore extremely important to maintain or improve healthy bone and calcium metabolism during and before the climacteric from a preventive medicine viewpoint. The specific preventive measures are appropriate calcium intake and regular physical exercise. In recent years, women in their twenties are considerably thinner and have a lower calcium intake than women in other age groups, which may lead to a further increase in the number of women with osteoporosis in the future...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28432417/exploring-the-possibility-of-a-retrograde-embolism-pathway-from-the-facial-artery-to-the-ophthalmic-artery-system-in-vivo
#6
Hui Zheng, Lihong Qiu, Zonghui Liu, Yingjun Su, Xinyuan Pan, Sha Liu, Chenggang Yi
BACKGROUND: Blindness caused by soft tissue fillers is an extremely low-probability event, but it results in great concern because of its devastating consequences. Currently, the mechanism of an embolism is usually considered to be an accidental injection of fillers into the blood vessels of the face, such as a facial artery, and then retrograding into the ophthalmic artery system, which causes retinal ischemic necrosis. In addition, previous studies have shown that there are anastomoses between facial arteries and branches of the ophthalmic artery in cadavers...
April 21, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28429694/the-rationale-and-design-of-the-national-familial-hypercholesterolemia-registries-in-turkey-a-hit1-and-a-hit2-studies
#7
Meral Kayıkçıoğlu, Lale Tokgözoğlu
OBJECTIVE: Familial hypercholesterolemia (FH) is a genetic disease characterized by extremely high levels of cholesterol, leading to premature atherosclerosis. Although many countries have already addressed the burden of FH by means of national registries, Turkey has no national FH registry or national screening program to detect FH. Creation of a series of FH registries is planned as part of Turkish FH Initiative endorsed by the Turkish Society of Cardiology to meet this need. This article provides detailed information on the rationale and design of the first 2 FH registries (A-HIT1 and A-HIT2)...
April 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28427561/molecular-targets-of-ascochlorin-and-its-derivatives-for-cancer-therapy
#8
Jason Chua Min-Wen, Benjamin Chua Yan-Jiang, Srishti Mishra, Xiaoyun Dai, Junji Magae, Ng Shyh-Chang, Alan Prem Kumar, Gautam Sethi
Cancer is an extremely complex disease comprising of a multitude of characteristic hallmarks that continue to evolve with time. At the genomic level, random mutations leading to deregulation of diverse oncogenic signal transduction cascades and polymorphisms coupled with environmental as well as life style-related factors are major causative agent contributing to chemoresistance and the failure of conventional therapies as well as molecular targeted agents. Hence, there is an urgent need to identify novel alternative therapies based on alternative medicines to combat this dreaded disease...
2017: Advances in Protein Chemistry and Structural Biology
https://www.readbyqxmd.com/read/28426677/information-ranks-highest-expectations-of-female-adolescents-with-a-rare-genital-malformation-towards-health-care-services
#9
Elisabeth Simoes, Alexander N Sokolov, Andrea Kronenthaler, Hanna Hiltner, Norbert Schaeffeler, Katharina Rall, Esther Ueding, Monika A Rieger, Anke Wagner, Leonie S Poesch, Marie-Christin Baur, Judith Kittel, Sara Y Brucker
BACKGROUND: Access to highly specialized health care services and support to meet the patient's specific needs is critical for health outcome, especially during age-related transitions within the health care system such as with adolescents entering adult medicine. Being affected by an orphan disease complicates the situation in several important respects. Long distances to dedicated institutions and scarcity of knowledge, even among medical doctors, may present major obstacles for proper access to health care services and health chances...
2017: PloS One
https://www.readbyqxmd.com/read/28424804/acute-medicine-finishing-school-preparing-for-the-next-step
#10
Tehmeena Khan, Nicholas Murch
The transition from registrar to consultant in medicine is one that trainees feel ill prepared for and can be extremely stressful. We devised the concept of an Acute Medicine "Finishing School" for senior trainees in London training programmes and ran sessions on CV writing, a simulated consultant interview, consultant job planning, responding to complaints and an out of hospital emergency scenario. Our feedback survey indicated that our delegates' confidence levels in all of the above aspects increased following the sessions...
2017: Acute Medicine
https://www.readbyqxmd.com/read/28423974/competitive-bass-anglers-a-new-concern-in-sports-medicine
#11
Connor R Read, Shawna L Watson, Jorge L Perez, A Reed Estes
OBJECTIVE: Competitive bass angling involves sport fishing against other anglers while targeting a species of fish known as the black basses. Due to the rapidly growing popularity of high school competitive bass angling in Alabama and the nature of the casting motion similar to that of overhead athletes, we sought to examine the prevalence of sports type injuries in this population. METHODS: In spring 2016, an anonymous survey was distributed across two large scale competitive high school fishing tournaments, allowing for a broad sampling of anglers throughout the state of Alabama...
April 19, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28419590/cracking-the-neural-code-treating-paralysis-and-the-future-of-bioelectronic-medicine
#12
C Bouton
The human nervous system is a vast network carrying not only sensory and movement information, but also information to and from our organs, intimately linking it to our overall health. Scientists and engineers have been working for decades to tap into this network and 'crack the neural code' by decoding neural signals and learning how to 'speak' the language of the nervous system. Progress has been made in developing neural decoding methods to decipher brain activity and bioelectronic technologies to treat rheumatoid arthritis, paralysis, epilepsy and for diagnosing brain-related diseases such as Parkinson's and Alzheimer's disease...
April 16, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28418938/a-study-on-postmortem-wound-dating-by-gross-and-histopathological-examination-of-abrasions
#13
Javaregowda Vinay, Sathyanarayana Harish, Gouri S R Mangala, Basappa S Hugar
INTRODUCTION: Abrasions are the most common blunt force injuries. The precise dating of injury is extremely important in forensic medicine practice. As we know, the wound healing occurs in well-orchestrated sequence, consisting of inflammation, proliferation, and maturation.A study of occurrence of such phases will help in understanding the sequence of events in wound healing. In this context, this study of wound dating from gross and microscopic level was taken. MATERIALS AND METHODS: Postmortem study of wound dating by gross and histopathological examination of abrasions was carried out in the Department of Forensic Medicine, in M...
April 17, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28417597/ultrahigh-water-content-superelastic-and-shape-memory-nanofiber-assembled-hydrogels-exhibiting-pressure-responsive-conductivity
#14
Yang Si, Lihuan Wang, Xueqin Wang, Ning Tang, Jianyong Yu, Bin Ding
High-water-content hydrogels that are both mechanically robust and conductive could have wide applications in fields ranging from bioengineering and electronic devices to medicine; however, creating such materials has proven to be extremely challenging. This study presents a scalable methodology to prepare superelastic, cellular-structured nanofibrous hydrogels (NFHs) by combining alginate and flexible SiO2 nanofibers. This approach causes naturally abundant and sustainable alginate to assemble into 3D elastic bulk NFHs with tunable water content and desirable shapes on a large scale...
April 18, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28416374/comparing-originator-biologics-and-biosimilars-a-review-of-the-relevant-issues
#15
REVIEW
Corrado Blandizzi, Pier Luigi Meroni, Giovanni Lapadula
PURPOSE: We provide a review of current knowledge on comparability between biosimilars and originator biologics in view of the continuous evolution occurring in this highly dynamic area. METHODS: English-language literature indexed in MEDLINE was explored, without time limits, to July 31, 2016, using the terms biosimilar, biotechnologic drug, biologic drug, monoclonal antibody, fusion protein, and anti-tumor necrosis factor. The reference lists of identified articles were examined carefully for additional pertinent publications...
April 14, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28414674/a-clot-possibly-due-to-loss-of-tnf-%C3%AE-supression
#16
J Broussard, M Berlinger, D Lauret
INTRODUCTION: Inflammation and venous thrombosis enjoy a close Relationship. We present a patient who had multiple DVTs following the discontinuation of anti- TNF-α therapy. CASE: A 34 year old African American female with a history of multiple DVT's, miscarriages, and reported Crohn's disease presented with shortness of breath. In the Emergency Department, CTA showed bilateral pulmonary emboli. The patient had been off adalimumab for one year and reported abdominal pain with 6-7 non-bloody bowel movements daily...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28412073/pediatric-acute-flaccid-paralysis-enterovirus-d68-associated-anterior-myelitis
#17
James A Yoder, Michael Lloyd, Luke Zabrocki, Jonathan Auten
BACKGROUND: Enteroviral infections can cause acute flaccid paralysis secondary to anterior myelitis. Magnetic resonance imaging (MRI) is important in the diagnosis of this potentially devastating pediatric disease. Before the 2014 outbreak of Enterovirus D68 (EV-D68), the virus was considered a relatively benign disease. CASE REPORT: A fully immunized 8-year-old boy was brought to the emergency department complaining of a cough, headache, neck pain, and right arm pain and weakness...
April 12, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28410445/integrative-skin-care-dermatology-and-traditional-and-complementary-medicine
#18
Gerard Bodeker, Terence J Ryan, Adva Volk, Jahnavi Harris, Gemma Burford Mbiochem
Skin problems and diseases are extremely common globally and, due to their visibility, often result in severe distress and stigma for sufferers. Traditional (i.e., indigenous or local) and complementary health systems are widely used and incorporate many treatment modalities suitable for skin care, and a body of evidence for their efficacy and safety has built up over many decades. These approaches are often used as part of a broader "integrative medicine" (IM) approach that may also include, for example, nutrition and mind-body approaches...
April 14, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28409758/improving-neonatal-intubation-safety-a-journey-of-a-thousand-miles
#19
T Sawyer, E Foglia, L Dupree Hatch, A Moussa, A Ades, L Johnston, A Nishisaki
Neonatal intubation is one of the most common procedures performed by neonatologists, however, the procedure is difficult and high risk. Neonates who endure the procedure often experience adverse events, including bradycardia and severe oxygen desaturations. Because of low first attempt success rates, neonates are often subjected to multiple intubation attempts before the endotracheal tube is successfully placed. These factors conspire to make intubation one of the most dangerous procedures in neonatal medicine...
2017: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/28408851/prilocaine-hydrochloride-2-hyperbaric-solution-for-intrathecal-injection-a-clinical-review
#20
REVIEW
Alberto Manassero, Andrea Fanelli
Prilocaine is a local anesthetic characterized by intermediate potency and duration and fast onset of action. As hyperbaric formulation of 5% solution, it was introduced and has been successfully used for spinal anesthesia since 1960. A new formulation of 2% plain and hyperbaric solution is currently available in Europe. Because of its lower incidence of transient neurological symptoms, prilocaine is suggested as substitute to lidocaine and mepivacaine in spinal anesthesia for ambulatory surgery, as well as a suitable alternative to low doses of long-acting local anesthetics...
2017: Local and Regional Anesthesia
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