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neonatal complication of premature rupture of membrane

Linling Zhu, Yu Zhang, Yifeng Liu, Runjv Zhang, Yiqing Wu, Yun Huang, Feng Liu, Meigen Li, Saijun Sun, Lanfeng Xing, Yimin Zhu, Yiyi Chen, Li Xu, Liangbi Zhou, Hefeng Huang, Dan Zhang
This study was carried out to explore associations between assisted reproductive technology (ART) and maternal and neonatal outcomes compared with similar outcomes following spontaneously conceived births. We conducted a retrospective cohort study of pregnancies conceived by ART (N = 2641) during 2006-2014 compared to naturally conceived pregnancies (N = 5282) after matching for maternal age and birth year. Pregnancy complications, perinatal complications and neonatal outcomes of enrolled subjects were investigated and analysed by multivariate logistic regression...
October 20, 2016: Scientific Reports
Sarah M Holmen, Tiki Bakhshi, Maria M Molina, Larissa F Weir
BACKGROUND: Chorioamniotic membrane separation (CMS) is a rare finding that is commonly preceded by invasive fetal procedures. The presence of CMS can also be associated with uncommon maternal or fetal conditions as well as preterm delivery, amniotic band syndrome, umbilical cord complications, and fetal and neonatal death. It is classified as a high-risk antepartum condition due to the significant fetal morbidity and mortality that may ensue. CASE REPORT: A 40-year-old gravida 5 para 1212 at 35 weeks presented for antepartum fetal testing...
October 2016: Military Medicine
Mariya Angelova, Emil Kovachev, Veselina Tsankova, Iliana Koleva, Silvia Mangarova
AIM: The aim of this study was to assess the prevalence of chlamydial infection among pregnant women and to determine the role of this infection in the fetus. MATERIAL AND METHODS: In the first phase of this study were reported 58 pregnant women with a positive test for active chlamydial infection by applying immunofluorescence. In the second phase of the study were reported pregnant with premature burst membranes (PBM), postnatal complications associated with chlamydial infection as puerperal endometritis, and newborns are monitored for low birth weight and growth retardation at birth...
September 15, 2016: Open Access Macedonian Journal of Medical Sciences
Tal Saar, Lorinne Levitt, Hagai Amsalem
Background. Late pregnancy usage of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin II receptor blockers (ARB) may cause severe oligohydramnios due to fetal renal impairment. Affected neonates will often suffer from fatal, renal, and respiratory failure. Case. A 39-year-old multigravida admitted due to anhydramnios secondary to valsartan (ARB) exposure at 30 weeks' gestation. Following secession of treatment amniotic fluid volume returned to normal. Delivery was induced at 34 weeks' gestation following premature rupture of membranes and maternal fever...
2016: Case Reports in Obstetrics and Gynecology
Meryem Kurek Eken, Abdülhamit Tüten, Enis Özkaya, Güner Karatekin, Ateş Karateke
OBJECTIVE: To assess the predictors of outcome in terms of length of stay in the neonatal intensive care unit (NICU) and survival of neonates from women with preterm premature rupture of membranes (PPROM). METHODS: A population-based retrospective study including three hundred thirty-one singleton pregnant women with PPROM at 24-34 gestational weeks between January 2013 and December 2015 was conducted. Gestational age at delivery, birth weight, route of delivery, newborn gender, maternal age,oligohydramnios, premature retinopathy (ROP), necrotising enterocolitis (NEC), sepsis, fetal growth retardation (FGR), intracranial hemorrhagia (ICH), bronchopulmonary dysplasia (BPD), respiratory distress syndrome (RDS), primary pulmonary hypertension (PPH), congenital cardiac disease (CCD), patent ductus arteriosus (PDA), use of cortisol (betamethasone) and maternal complications including gestational diabetes, preeclampsia, and chorioamnionitis were used to predict neonatal outcomes in terms of length of stay in the NICU and survival...
September 14, 2016: Journal of Maternal-fetal & Neonatal Medicine
Olivia Myrick, Sarah Dotters-Katz, Matthew Grace, Tracy Manuck, Kim Boggess, William Goodnight
OBJECTIVE: This study aims to determine if antibiotics given for latency to women with twins and previable preterm premature rupture of membranes (PPROM) affect the duration from membrane rupture to delivery. METHODS: A retrospective cohort study of twin pregnancies at a single center from 2000 to 2015 with previable (14 (0/7)-22 (6/7) weeks) PPROM was conducted. Women who were not candidates for expectant management or who elected for immediate delivery were excluded...
July 2016: American Journal of Perinatology Reports
Kishwar Azad, Jiji Mathews
Preterm births (PTBs), defined as births before 37 weeks of gestation account for the majority of deaths in the newborn period. Prediction and prevention of PTB is challenging. A history of preterm labour or second trimester losses and accurate measurement of cervical length help to identify women who would benefit from progesterone and cerclage. Fibronectin estimation in the cervicovaginal secretions of a symptomatic woman with an undilated cervix can predict PTB within 10 days of testing. Antibiotics should be given to women with preterm prelabour rupture of membranes but tocolysis has a limited role in the management of preterm labour...
June 24, 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
Dana Sadeh-Mestechkin, Nivin Samara, Amir Wiser, Ofer Markovitch, Gil Shechter-Maor, Tal Biron-Shental
PURPOSE: To compare maternal and neonatal outcomes in induced vs. expectant management of term PROM. METHODS: This retrospective study included patients with term PROM. A total of 325 were enrolled: 213 managed expectantly and 112 induced at admission and matched according to gestational age. Expectant management group patients were allowed to defer labour induction up to 48 h. Primary outcome measures were maternal or foetal signs of infection (chorioamnionitis, early neonatal sepsis or postpartum endometritis) and prolonged maternal hospitalization...
August 8, 2016: Archives of Gynecology and Obstetrics
Shun-Yan Duan, Xiang-Yong Kong, Feng-Dan Xu, Hong-Yan Lv, Rong Ju, Zhan-Kui Li, Shu-Juan Zeng, Hui Wu, Xue-Feng Zhang, Wei-Peng Liu, Fang Liu, Hong-Bin Cheng, Yan-Jie Ding, Tie-Qiang Chen, Ping Xu, Li-Hong Yang, Su-Jing Wu, Jin Wang, Li Peng, Xiao-Lin Zhao, Hui-Xian Qiu, Wei-Xi Wen, Ying Li, Lan Li, Zheng Wen, Guo Guo, Feng Wang, Gai-Mei Li, Wei Li, Xiao-Ying Zhao, Yun-Bo Xu, Wen-Chao Chen, Huan Yin, Xiao-Liang Wang, Rui-Yan Shan, Mei-Ying Han, Chun-Yan Yang, Zhi-Chun Feng
OBJECTIVE: To investigate the effect of premature rupture of the membrane (PROM) on neonatal complications in premature infants. METHODS: The registration information of 7684 preterm infants with gestational age <37 weeks were collected from the cooperative units in the task group between January 1, 2014 to December 31, 2014. Specially trained personnel from each cooperative units filled in the unified form in a standardized format to record the gender, gestational age, birth weight, PROM, placental abruption, antenatal corticosteroid, Apgar score, amniotic fluid pollution, and complications of the infants...
June 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Mia Kibel, Elizabeth Asztalos, Jon Barrett, Michael S Dunn, Carly Tward, Alex Pittini, Nir Melamed
OBJECTIVE: To assess the natural history and contemporary outcomes in pregnancies complicated by previable preterm premature rupture of membranes (PROM). METHODS: Retrospective study of all women with a singleton or twin pregnancy admitted to a single tertiary referral center who experienced preterm PROM between 20 and 23 6/7 weeks of gestation during 2004-2014 and underwent expectant management. Women electing termination of pregnancy and pregnancies complicated by major fetal anomalies were excluded...
August 2016: Obstetrics and Gynecology
Adele E Crowley, Rosalie M Grivell, Jodie M Dodd
BACKGROUND: Preterm prelabour rupture of the membranes (PPROM) complicates approximately 2% of pregnancies and can be either spontaneous or iatrogenic in nature. Complications of PPROM include prematurity, chorioamnionitis, neonatal sepsis, limb position defects, respiratory distress syndrome, pulmonary hypoplasia chronic lung disease, periventricular leukomalacia and intraventricular haemorrhage.A number of different sealing techniques have been employed which aim to restore a physical barrier against infection and encourage the re-accumulation of amniotic fluid...
2016: Cochrane Database of Systematic Reviews
Florentina Sava, Gergely Toldi, András Treszl, Júlia Hajdú, Ágnes Harmath, Tivadar Tulassay, Barna Vásárhelyi
BACKGROUND: Inappropriate activation of T lymphocytes plays an important role in perinatal complications. However, data on T lymphocyte activation markers of preterm infants is scarce. We investigated the association between gender, gestational and postnatal age, preeclampsia (PE), premature rupture of membranes (PROM) as well as prenatal steroid treatment (PS) and the frequency of activated T lymphocyte subsets (HLA-DR+, CD69+, CD25+, CD62L+) and major T lymphocyte subpopulations (CD4, CD8, Th1, Th2, naïve, memory) in peripheral blood during the first postnatal week in preterm infants...
2016: BMC Immunology
Orkun Cetin, Zuhal Dilek Aydın, Fatma Ferda Verit, Ali Galip Zebitay, Erbil Karaman, Sadi Elasan, Mehtap Turfan, Oguz Yucel
BACKGROUND: This study is aimed at comparing the early diagnostic accuracy of maternal blood white blood cell (WBC) count, C-reactive protein (CRP) and procalcitonin in predicting early onset neonatal sepsis (EONS) among early preterm premature rupture of membrane (PPROM) pregnancies. METHODS: A total of 57 consecutive pregnancies, complicated with PPROM, between 24 and 34 gestational weeks were recruited to the study at Suleymaniye Maternity Education and Research Hospital, Istanbul, Turkey between January 2012 and January 2013...
June 15, 2016: Gynecologic and Obstetric Investigation
Elisabeth Catt, Rati Chadha, Selphee Tang, Elizabeth Palmquist, Ian Lange
OBJECTIVES: We sought to evaluate the safety of outpatient management of pregnancy complicated by preterm premature rupture of membranes (PPROM). STUDY DESIGN: We performed a retrospective cohort study of women with PPROM and a latency period of at least one week in one provincial health region between January 2007 and December 2012. We evaluated pregnancy outcomes for 133 women whose cases were managed using specialized community care and compared these with outcomes of a similar group of 122 women whose cases were managed entirely in the hospital...
May 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Eran Ashwal, Eyal Krispin, Amir Aviram, Ella Aleyraz, Rinat Gabby-Benziv, Arnon Wiznitzer, Yariv Yogev, Liran Hiersch
PURPOSE: We aimed to evaluate perinatal outcome in women with prolonged (>24 h) premature rupture of membranes (PROM) undergoing induction of labor (IoL). METHODS: We retrospectively assessed all women presenting with term (≥37 weeks) PROM and Bishop-score <7 in a tertiary hospital (2012-14). Women without spontaneous onset of labor <24 h from PROM underwent Prostaglandin E2 (PGE2) IoL and were compared to women with low Bishop-score who developed spontaneous onset of labor <24 h...
May 27, 2016: Archives of Gynecology and Obstetrics
Amol Malshe, Saul Snowise, Lovepreet K Mann, Noemi Boring, Anthony Johnson, Michael W Bebbington, Kenneth J Moise, Ramesha Papanna
BACKGROUND: Preterm delivery after fetoscopic laser surgery (FLS) for twin-twin transfusion syndrome (TTTS) remains a major challenge. The causative factors leading to preterm delivery continue to be elusive and better understanding of the risk factors could reduce complications. The objectives of this study was to determine the etiology for preterm delivery after FLS for TTTS and its associated risk factors. METHODS: This is a secondary analysis of a prospective study of 203 patients with TTTS who underwent FLS at a single center...
May 25, 2016: Ultrasound in Obstetrics & Gynecology
Femke Slaghekke, Dick Oepkes
Monochorionic twin pregnancies can be complicated by twin-to-twin transfusion syndrome (TTTS). The best treatment option for TTTS is fetoscopic laser coagulation of the vascular anastomoses between donor and recipient. After laser therapy, up to 33% residual anastomoses were seen. These residual anastomoses can cause twin anemia polycythemia sequence (TAPS) and recurrent TTTS. In order to reduce the number of residual anastomoses and their complications, a new technique, the Solomon technique, where the whole vascular equator will be coagulated, was introduced...
June 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
Saul Snowise, Lovepreet K Mann, Kenneth J Moise, Anthony Johnson, Michael W Bebbington, Ramesha Papanna
OBJECTIVE: To assess the incidence, clinical course, risk factors and outcomes of preterm premature rupture of membranes (PPROM) after fetoscopic laser photocoagulation (FLP). STUDY DESIGN: This was a prospective observational cohort study of 154 consecutive twin-twin transfusion syndrome (TTTS) cases. PPROM was defined as rupture of membranes ≤34 weeks gestation. Procedure-to-PPROM and PPROM-to-delivery intervals were both determined. Relevant preoperative and intra-operative variables were analyzed by univariate and multivariate logistic regression to determine their impact on PPROM after FLP...
May 6, 2016: Ultrasound in Obstetrics & Gynecology
Ai-Ming Cui, Xiao-Yan Cheng, Jian-Guo Shao, Hai-Bo Li, Xu-Lin Wang, Yi Shen, Li-Jing Mao, Sheng Zhang, Hai-Yun Liu, Lei Zhang, Gang Qin
BACKGROUND: Infection with hepatitis B virus (HBV) in pregnant women may be a threat for both mothers and fetuses. This study was performed to explore the impact of maternal HBV carrier status on pregnancy outcomes. METHODS: We conducted a prospective cohort study at the Obstetrics & Gynecology Hospital of Nantong University between January 1, 2012 and September 30, 2015. A consecutive sample of 21,004 pregnant women, 513 asymptomatic HBV carriers and 20,491 non-HBV controls, was included in this study...
2016: BMC Pregnancy and Childbirth
Chian-Huey Wong, Chie-Pein Chen, Kuo-Gon Wang, Fang-Ju Sun, Chen-Yu Chen
OBJECTIVE: To investigate the outcomes of singleton pregnant women with cervical insufficiency undergoing two different cervical cerclages. METHODS: This is a retrospective cohort study of women who underwent a history- or ultrasound-indicated cerclage (either Shirodkar or McDonald) at a tertiary referral center from 2002 to 2014. Outcome parameters (delivery age, postoperative cervical length, preterm premature rupture of membranes, preterm delivery rate and neonatal complications) were compared between the two cerclage procedures...
May 5, 2016: Journal of Maternal-fetal & Neonatal Medicine
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