A Gessain, F Saal, V Morozov, J Lasneret, D Vilette, O Gout, R Emanoil-Ravier, F Sigaux, G de Thé, J Périès
Lymphoid cell lines derived from the peripheral blood of French West Indian patients with HTLV-I sero-positive Tropical Spastic Paraparesis and HTLV-I isolates were characterized. While patients' peripheral blood lymphocytes did not express detectable HTLV-I antigens when uncultured, they did so after short-term culture. Established cell lines were of T-cell lineage: CD2+, CD3+, CD4+, CD7+, WT31+ with activated T-cell markers CD25+, DR+ and a clonal rearrangement of the beta and gamma genes of the T-cell receptor...
February 15, 1989: International Journal of Cancer. Journal International du Cancer