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Transverse Myelopathy

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https://www.readbyqxmd.com/read/27898552/a-young-woman-with-numbness-in-her-feet
#1
Daniel Pavlik, Michael Huber, Melissa Justice
This article describes a young, otherwise healthy woman who presented to the ED with numbness in her feet and was discharged. Twenty-four hours later, she returned because of difficulty walking; in 48 hours she could not walk without assistance. Although Guillain-Barré syndrome was suspected initially, the patient's weakness, sensory loss, and autonomic dysfunction eventually were diagnosed as transverse myelitis, a myelopathy often associated with infectious or autoimmune diseases. The article describes the presentation, diagnostic evaluation and criteria, treatment, and prognosis of transverse myelitis...
December 2016: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/27865885/perforations-and-angulations-of-324-cervical-medial-cortical-pedicle-screws-a-possible-guide-to-avoid-lateral-perforations-with-use-of-pedicle-screws-in-lower-cervical-spine
#2
Bijjawara Mahesh, Bidre Upendra, Sekharappa Vijay, Kumar Arund, Reddy Srinivas
BACKGROUND: Context : More than half of the perforations reported with usage of cervical pedicle screws (CPS), are lateral perforations, endangering the vertebral artery. The medial cortical pedicle screw technique (MCPS) with partial drilling of the medial cortex, shifts the trajectory of pedicle screws medially, decreasing the lateral perforations. PURPOSE: To evaluate the decrease in lateral perforations of CPS with use of MCPS technique, in relation to medial angulation...
November 16, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27858382/dorsal-arachnoid-web-and-scalpel-sign-a-diagnostic-imaging-entity
#3
Leonardo Gilmone Ruschel, Guilherme José Agnoletto, Lucas Alves Aurich, Ronaldo Pereira Vosgerau
MATERIAL AND METHODS: A case of 60-year-old woman with idiopathic syringomyelia and progressive myelopathy by dorsal arachnoid web is discussed. One focal indentation along the dorsal surface of the spinal cord at the T3 vertebral body level revealed the scalpel sign, a radiologic entity diagnostic of a dorsal thoracic arachnoid web. RESULTS: T2-T3 laminectomy for the resection of dorsal arachnoid band was performed. Careful sectioning of the web resulted in visual apparent relief of the compression and good functional recovery...
October 14, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27673101/poster-348-biospy-confirmed-neurosarcoidosis-manifesting-as-a-non-compressive-myelopathy-with-transverse-myelitis-and-normal-ace-level-a-case-study
#4
Brandon Trivax, Alexandra Paraskos, Dena Abuelroos, Aishwarya Navalpakam
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27616314/an-imaging-based-approach-to-spinal-cord-infection
#5
Jason F Talbott, Jared Narvid, J Levi Chazen, Cynthia T Chin, Vinil Shah
Infections of the spinal cord, nerve roots, and surrounding meninges are uncommon, but highly significant given their potential for severe morbidity and even mortality. Prompt diagnosis can be lifesaving, as many spinal infections are treatable. Advances in imaging technology have now firmly established magnetic resonance imaging (MRI) as the gold standard for spinal cord imaging evaluation, enabling the depiction of infectious myelopathies with exquisite detail and contrast. In this article, we aim to provide an overview of MRI findings for spinal cord infections with special focus on imaging patterns of infection that are primarily confined to the spinal cord, spinal meninges, and spinal nerve roots...
October 2016: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/27572861/pediatric-transverse-myelitis
#6
Michael Absoud, Benjamin M Greenberg, Ming Lim, Tim Lotze, Terrence Thomas, Kumaran Deiva
Pediatric acute transverse myelitis (ATM) is an immune-mediated CNS disorder and contributes to 20% of children experiencing a first acquired demyelinating syndrome (ADS). ATM must be differentiated from other presentations of myelopathy and may be the first presentation of relapsing ADS such as neuromyelitis optica (NMO) or multiple sclerosis (MS). The tenets of the diagnostic criteria for ATM established by the Transverse Myelitis Consortium Working Group can generally be applied in children; however, a clear sensory level may not be evident in some...
August 30, 2016: Neurology
https://www.readbyqxmd.com/read/27526974/etiological-clinical-and-radiological-features-of-longitudinally-extensive-myelopathy-in-chinese-patients
#7
Weihe Zhang, Yujuan Jiao, Lei Cui, Lei Liu, Linwei Zhang, Jinsong Jiao
Longitudinally extensive myelopathy (LEM) is a rare spinal syndrome, and was mostly assessed in western populations. In order to investigate the etiological, clinical, and radiological features of LEM in Chinese patients, we retrospectively analyzed eighty-nine (40 men and 49 women, median age 45.9±15.7years) patients with LEM hospitalized in China-Japan Friendship Hospital. LEM comprised autoimmune inflammatory myelitis (n=53), metabolic and compressive disorders (n=13), vascular diseases (n=10), neoplastic diseases (n=7), infectious diseases (n=4), and syringomyelia (n=2)...
October 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27452920/acute-flaccid-weakness-with-myelopathy-and-peripheral-nerve-involvement-in-2-children-recent-characterization-of-a-previously-observed-phenomenon
#8
Gemma Olive, Antonia Clarke, Katja Doerholt, Vasantha Gowda, Atta Siddiqui, Ming J Lim
BACKGROUND: Acute flaccid weakness may be the first presentation of acute transverse myelitis (ATM), an immune-mediated central nervous system disorder or may be the first presentation of anterior horn cell syndrome or peripheral nervous system disease. CASE REPORTS: We describe two previously healthy female infants who presented with acute flaccid paralysis and encephalopathy. Neuroimaging revealed central cord signal changes in both cases and surprisingly electrophysiological studies performed revealed a generalized axonal motor neuropathy as well...
December 0: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/27443995/imaging-manifestations-of-neurologic-complications-in-anemia
#9
REVIEW
Ritesh Patel, Shyam Sabat, Sangam Kanekar
The hallmark signs and symptoms of anemia are directly related to a decrease in oxygen delivery to vital tissues and organs and include pallor, fatigue, lightheadedness, and shortness of breath. Neurologic complications are often nonspecific and can include poor concentration, irritability, faintness, tinnitus, and headache. If undiagnosed or untreated, anemia can progress to cognitive dysfunction, psychosis, encephalopathy, myelopathy, peripheral neuropathy, and more focal syndromes, such as stroke, seizures, chorea, and transverse myelitis...
August 2016: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/27366255/radiological-study-of-c3-c4-level-surgical-cases-of-cervical-spondylosis
#10
Masato Tomii, Junichi Mizuno, Kazuo Watanabe
OBJECTIVE: The purpose of this study was to elucidate the pathological characteristics of C3-C4 cervical spondylotic myelopathy (CSM) from the radiological study. MATERIALS AND METHODS: A total of 31 patients with single level anterior cervical discectomy and fusion (ACDF) at C3-C4 and 46 patients with single level ACDF at C5-C6 were included in this study. We selected C5-C6 level as a representative of the lower cervical level. The C3-C4 and C5-C6 levels were routinely examined to investigate the areas of the vertebral canal, subarachnoid space, and spinal cord in the cervical canal...
July 2016: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/27338214/efficacy-and-safety-of-one-stage-selective-discectomy-combined-with-expansive-hemilaminectomy-in-treatment-of-cervical-spondylotic-myelopathy
#11
Guoyun Bu, Feng Shuang, Gang Liu, Ye Wu, Shuxun Hou, Dongfeng Ren, Weilin Shang
OBJECTIVES: We designed a novel surgical strategy named one-stage selective discectomy combined with expansive hemilaminectomy (OSDEHL) which might theoretically reduce the postoperative complications of Cervical Spondylotic Myelopathy (CSM). The objectives of this study is to evaluate its efficacy and safety. METHODS: 62 patients with CSM were enrolled in this study. The procedure includes selective discectomy with fusion at 1 or 2 segments of maximal cord compression and expansive hemilaminectomy on the symptomatic or severe side of the body...
June 20, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27313742/transverse-myelopathy-occurring-with-intrathecal-administration-of-methotrexate-and-cytarabine-chemotherapy-a-case-report
#12
Ying Pan, Chunhuai Wang, Huiping Wang, Qianshan Tao, Shudao Xiong, Zhimin Zhai
Paraplegia following spinal injury is a rare complication subsequent to the administration of intrathecal chemotherapy; however, it is also one of the rare clinical features of central nervous system leukemia (CNSL). Distinguishing between the two is extremely important. The present study reports the case of a 46-year-old man who was diagnosed with acute lymphoblastic leukemia and subsequently achieved remission in the blood and bone marrow following the initial course of chemotherapy. However, the patient developed a sudden onset of paraplegia and urinary retention due to spinal cord infiltration of leukemia cells following the administration of intrathecal methotrexate and cytarabine...
June 2016: Oncology Letters
https://www.readbyqxmd.com/read/27242943/concomitant-guillain-barre-syndrome-and-transverse-myelitis-as-initial-neuropsychiatric-manifestation-in-a-case-of-lupus-a-diagnostic-quandary
#13
Anshuman Srivastava, Bijit Kumar Kundu, Diwakar Kumar Singh
Neuropsychiatric manifestations of systemic lupus erythematosus are varied. Presently nineteen in number, they are classified as whether affecting the central or the peripheral compartments of the nervous system. Its diagnosis however remains difficult, more so when two or more of the syndromes are found concomitantly in the same patient and when they occur in absence of the more classical rash, serositis, and haematological manifestations. We present a case of lupus where myelopathy as well as demyelination existed simultaneously as the initial neurologic manifestation...
2016: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/27171661/correlation-between-spinal-cord-function-assessed-by-intraoperative-sceps-and-morphology-of-the-compressed-spinal-cord-on-mri
#14
Tsukasa Kanchiku, Yasuaki Imajo, Hidenori Suzuki, Yuichiro Yoshida, Kosuke Akashi, Toshihiko Taguchi
STUDY DESIGN: Retrospective study. OBJECTIVES: The objective of this study was to examine whether the morphology of the compressed spinal cord reflects spinal cord dysfunction in cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND: Segmental levels responsible for clinical symptoms in CSM are usually diagnosed by neurological examination and imaging studies such as magnetic resonance imaging (MRI). Electrophysiological examination makes it possible to assess the spinal cord function quantitatively...
December 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/26833287/fibrocartilaginous-embolism-a-comprehensive-review-of-an-under-studied-cause-of-spinal-cord-infarction-and-proposed-diagnostic-criteria
#15
Mahmoud A AbdelRazek, Ashkan Mowla, Salman Farooq, Nicholas Silvestri, Robert Sawyer, Gil Wolfe
BACKGROUND: Most spinal cord infarctions are due to aortic pathologies and aortic surgeries. Fibrocartilaginous Embolism (FCE) has been reported to represent 5.5% of spinal cord infarctions. Some believe that FCE is more common than presumed and is rather under-diagnosed due to vagueness surrounding its clinical presentation. METHOD: A literature search was conducted for case reports of FCE published before August 2014. PubMed, the Cochrane Central Register and Google Scholar were searched for different combinations of the key words "fibrocartilaginous, "nucleus pulposus", "embolism", "spinal cord", "inter-vertebral disc", "infarction", "stroke", "paraplegia", "quadriplegia", "myelopathy"...
2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/26787180/-influence-of-cervical-spondylotic-spinal-cord-compression-on-cerebral-cortical-adaptation-radiological-study
#16
L Hrabálek, P Hluštík, P Hok, E Čecháková, T Wanek, P Otruba, M Vaverka, P Kaňovský
PURPOSE OF THE STUDY: The aim of the study was to measure the sensorimotor brain adaptation activity, shown on functional magnetic resonance images (fMRI), in relation to the degree and extent of spinal cord compression or cervical spondylotic myelopathy (CSM) detected by cervical spine MRI. MATERIAL AND METHODS: Twenty-one patients (average age, 57 years; 9 men and 12 women) with anterior cervical cord compression detected on cervical MRI scans were included. On the images, the degree of spinal canal stenosis, the spinal cord compression based on the antero-posterior diameter of the spinal canal and on transverse areas of the cervical spinal cord and cervical spinal canal, and changes in spinal cord signal intensity were identified...
2015: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/26716140/a-reversible-cause-of-longitudinally-extensive-transverse-myelopathy-question
#17
Wladimir B V R Pinto, Paulo V S Souza, Acary S B Oliveira
No abstract text is available yet for this article.
November 2015: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/26712036/spectrum-of-nontraumatic-myelopathies-in-ethiopian-patients-hospital-based-retrospective-study
#18
N J Fidèle, A Amanuel
STUDY DESIGN: This is a retrospective hospital-based study. OBJECTIVES: The study aimed at a better understanding of the etiology, clinical presentation and treatment outcome of nontraumatic myelopathies in Ethiopian patients. SETTING: Etiologies of nontraumatic myelopathies have not been evaluated extensively in most sub-Saharan African countries. The available studies in this region were conducted before the widespread clinical use of modern neuroimaging modalities...
August 2016: Spinal Cord
https://www.readbyqxmd.com/read/26602804/spondylotic-myelopathy-mimicking-myelitis-diagnostic-clues-by-magnetic-resonance-imaging
#19
Adriana Rua, Yolanda Blanco, María Sepúlveda, Núria Sola-Valls, Eugenia Martínez-Hernández, Sara Llufriu, Joan Berenguer, Francesc Graus, Albert Saiz
INTRODUCTION: Spondylotic myelopathy is the commonest cause of nontraumatic myelopathy. Radiological features of spondylotic myelopathy can often overlap with inflammatory myelopathies which may lead to a delayed or incorrect diagnosis and therapy. A distinctive gadolinium enhancement pattern recently described may help to differentiate spondylotic from inflammatory myelopathy. CASE REPORTS: Case 1: a 38-years-old man presented with a 2-year history of paresthesias in the upper extremities, and one year later cramps on the right limbs and numbness over right C5 and C6 dermatomes, related to movement of the neck...
December 1, 2015: Revista de Neurologia
https://www.readbyqxmd.com/read/26538786/bilateral-abducent-palsy-in-leptospirosis-an-eye-opener-to-a-rare-neuro-ocular-manifestation-a-case-report
#20
Mahadevaiah Mahesh, Mamatha Shivanagappa, Chilkunda Raviprakash Venkatesh
Leptospirosis, a disease of great significance in tropical countries, presents commonly as a biphasic illness with acute febrile episode in the first phase followed by a brief afebrile period and then by the second phase of fever with or without jaundice and renal failure. However, it has varied manifestations and unusual clinical features ascribed to immunological phenomena can occur due to the additional involvement of pulmonary, cardiovascular, and neurological systems. Among the various neurological features, aseptic meningitis is the most common myeloradiculopathy, myelopathy, cerebellar dysfunction, transverse myelitis, Guillain-Barre syndrome, optic neuritis, peripheral neuropathy hare also described...
November 2015: Iranian Journal of Medical Sciences
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