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https://www.readbyqxmd.com/read/28433830/spasticity-management-the-current-state-of-transcranial-neuromodulation
#1
REVIEW
Antonino Leo, Antonino Naro, Francesco Molonia, Provvidenza Tomasello, Ileana Saccà, Alessia Bramanti, Margherita Russo, Placido Bramanti, Angelo Quartarone, Rocco Salvatore Calabrò
This narrative review aims to provide an objective view of the non-invasive neuromodulation (NINM) protocols available for treating spasticity, including repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS). On the basis of the relevant randomized controlled trials, we infer that NINM is more effective in reducing spasticity when combined with the conventional therapies than used as a stand-alone treatment. However, the magnitude of NINM aftereffects depends significantly on the applied hemisphere and the underlying pathology...
April 19, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28432855/a-systematic-review-of-psychotherapeutic-interventions-for-women-with-metastatic-breast-cancer-context-matters
#2
REVIEW
Lisa Beatty, Emma Kemp, Phyllis Butow, Afaf Girgis, Penelope Schofield, Jane Turner, Nicholas J Hulbert-Williams, Janelle V Levesque, Bogda Koczwara
OBJECTIVES: To summarise the evidence-base of psychological interventions for women with metastatic breast cancer (MBC), by mode of delivery (group, individual, or low-intensity interventions). To synthesise data regarding core intervention-elements (e.g., intervention duration) and context factors (trial setting, uptake and adherence, demographic characteristics). METHODS: Four databases were searched (inception - May 2016): MEDLINE (OvidSP), PsycINFO (OvidSP), CINAHL (EBSCO), and SCOPUS; reference lists were examined for additional publications...
April 22, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28427388/movement-cognition-and-narration-of-the-emotions-treatment-versus-standard-speech-therapy-in-the-treatment-of-children-with-borderline-intellectual-functioning-a-randomized-controlled-trial
#3
V Blasi, G Baglio, F Baglio, M P Canevini, M Zanette
BACKGROUND: Borderline intellectual functioning (BIF) is defined as a "health meta-condition… characterized by various cognitive dysfunctions associated with an intellectual quotient (IQ) between 71 and 85 which determines a deficit in the individual's functioning both in the restriction of activities and in the limitation of social participation". It can be caused by many factors, including a disadvantaged background and prematurity. BIF affects 7-12% of primary school children that show academic difficulties due to poor executive functioning...
April 20, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28425825/reviewing-treatments-and-outcomes-in-the-evolving-landscape-of-ulcerative-colitis
#4
Marla C Dubinsky
Ulcerative colitis (UC) is a chronic inflammatory disease extending proximally from the rectum to varying lengths of the colon that is characterized by alternating cycles of relapse and remission. Therapeutic goals for patients with active UC include induction and maintenance of remission and improvement in quality of life, as well as mucosal healing, a clinical outcome recently recognized in treatment guidance as being equally important. Mucosal healing is associated with favorable long-term patient outcomes related to remission, surgery, hospitalization, and quality of life...
April 20, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28424854/the-effectiveness-of-narrative-enhancement-and-cognitive-therapy-a-randomized-controlled-study-of-a-self-stigma-intervention
#5
Lars Hansson, Annika Lexén, Joacim Holmén
PURPOSE: Stigma has been proposed to be one of the most serious obstacles to successful treatment, rehabilitation and inclusion in society of people with severe mental illness. An aspect of stigma which has been increasingly discussed is self-stigma, which refers to the internalization of negative stereotypes among people with severe mental illness. The aim of the present study was to investigate the effectiveness of a group-based anti self-stigma intervention, narrative enhancement and cognitive therapy (NECT) as an add-on to treatment as usual, with regard to changes in self-stigma, self-esteem, and subjective quality of life...
April 19, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28420284/a-systematic-review-of-rehabilitation-interventions-to-prevent-and-treat-depression-in-post-stroke-aphasia
#6
Caroline Baker, Linda Worrall, Miranda Rose, Kyla Hudson, Brooke Ryan, Leana O'Byrne
PURPOSE: Stepped psychological care is the delivery of routine assessment and interventions for psychological problems, including depression. The aim of this systematic review was to analyze and synthesize the evidence of rehabilitation interventions to prevent and treat depression in post-stroke aphasia and adapt the best evidence within a stepped psychological care framework. METHOD: Four databases were systematically searched up to March 2017: Medline, CINAHL, PsycINFO and The Cochrane Library...
April 19, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28418852/structural-homologies-between-phenformin-lipitor-and-gleevec-aim-the-same-metabolic-oncotarget-in-leukemia-and-melanoma
#7
REVIEW
Gábor Somlyai, T Que Collins, Emmanuelle J Meuillet, Patel Hitendra, Dominic P D'Agostino, László G Boros
Phenformin's recently demonstrated efficacy in melanoma and Gleevec's demonstrated anti-proliferative action in chronic myeloid leukemia may lie within these drugs' significant pharmacokinetics, pharmacodynamics and structural homologies, which are reviewed herein. Gleevec's success in turning a fatal leukemia into a manageable chronic disease has been trumpeted in medical, economic, political and social circles because it is considered the first successful targeted therapy. Investments have been immense in omics analyses and while in some cases they greatly helped the management of patients, in others targeted therapies failed to achieve clinically stable recurrence-free disease course or to substantially extend survival...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28417456/interventions-to-improve-adherence-to-inhaled-steroids-for-asthma
#8
REVIEW
Rebecca Normansell, Kayleigh M Kew, Elizabeth Stovold
BACKGROUND: Despite its proven efficacy in improving symptoms and reducing exacerbations, many patients with asthma are not fully adherent to their steroid inhaler. Suboptimal adherence leads to poorer clinical outcomes and increased health service utilisation, and has been identified as a contributing factor to a third of asthma deaths in the UK. Reasons for non-adherence vary, and a variety of interventions have been proposed to help people improve treatment adherence. OBJECTIVES: To assess the efficacy and safety of interventions intended to improve adherence to inhaled corticosteroids among people with asthma...
April 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28408236/unintentional-pediatric-cocaine-exposures-result-in-worse-outcomes-than-other-unintentional-pediatric-poisonings
#9
Patil Armenian, Michelle Fleurat, George Mittendorf, Kent R Olson
BACKGROUND: Unintentional pediatric cocaine exposures are rare but concerning due to potentially serious complications such as seizures, dysrhythmias, and death. OBJECTIVES: The objectives were to assess the demographic and clinical characteristics of pediatric cocaine exposures reported to the California Poison Control System. METHODS: This is a retrospective study of all confirmed pediatric (< 6 years of age) cocaine exposures reported to the California Poison Control System from January 1, 1997-September 30, 2010...
April 10, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28406273/-we-are-part-of-a-family-benefits-and-limitations-of-community-art-groups-cags-in-thyolo-malawi-a-qualitative-study
#10
Umberto Pellecchia, Saar Baert, Spencer Nundwe, Andy Bwanali, Bote Zamadenga, Carol A Metcalf, Helen Bygrave, Sarah Daho, Liesbet Ohler, Brown Chibwandira, Kennedy Kanyimbo
INTRODUCTION: In 2012 Community ART Groups (CAGs), a community-based model of antiretroviral therapy (ART) delivery were piloted in Thyolo District, Malawi as a way to overcome patient barriers to accessing treatment, and to decrease healthcare workers' workload. CAGs are self-formed groups of patients on ART taking turns to collect ART refills for all group members from the health facility. We conducted a qualitative study to assess the benefits and challenges of CAGs from patients' and healthcare workers' (HCWs) perspectives...
March 28, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28403280/electropalatography-and-its-correlation-to-tongue-movement-ultrasonography-in-speech-analysis
#11
Luciana da Silva Barberena, Caroline Rodrigues Portalete, Simone Nicolini de Simoni, Ana Cristina Melo Prates, Márcia Keske-Soares, Renata Mancopes
Purpose: To analyze the use of electropalatography and ultrasonography regarding speech therapy through literature narrative review. Research strategies: A literature review was conducted at PubMed and Scielo databases, using descriptors as electropalatography, electropalatography AND evaluation, electropalatography AND therapy, electropalatography AND ultrasonography, electropalatography AND speech. Selection criteria: The research criteria selected in the database were: studies in the past five years and studies in humans...
April 10, 2017: CoDAS
https://www.readbyqxmd.com/read/28398996/lessons-learned-from-option-b-in-the-evolution-toward-test-and-start-from-malawi-cameroon-and-the-united-republic-of-tanzania
#12
Thokozani Kalua, Beth A Tippett Barr, Joep J van Oosterhout, Dorothy Mbori-Ngacha, Erik J Schouten, Sundeep Gupta, Amakobe Sande, Gerald Zomba, Hannock Tweya, Edgar Lungu, Deborah Kajoka, Pius Tih, Andreas Jahn
The acceleration of prevention of mother-to-child transmission (PMTCT) activities, coupled with the rollout of 2010 World Health Organization (WHO) guidelines, led to important discussions and innovations at global and country levels. One paradigm-shifting innovation was Option B+ in Malawi. It was later included in WHO guidelines and eventually adopted by all 22 Global Plan priority countries. This article presents Malawi's experience with designing and implementing Option B+ and provides complementary narratives from Cameroon and Tanzania...
May 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28398985/effectiveness-of-family-interventions-on-psychological-distress-and-expressed-emotion-in-family-members-of-individuals-diagnosed-with-first-episode-psychosis-a-systematic-review
#13
Wilai Napa, Patraporn Tungpunkom, Nisakorn Pothimas
BACKGROUND: A critical period for persons with first-episode psychosis is the first two years after diagnosis, when they are at high risk of suicide attempts, violent behaviors and substance abuse. This period also has a great impact on the psychological distress of family members, particularly caregivers who either provide care or live with ill family members. In addition, the families also report feelings of being overwhelmed when accessing service facilities at this critical point...
April 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28397633/psychosocial-interventions-for-children-and-adolescents-after-man-made-and-natural-disasters-a-meta-analysis-and-systematic-review
#14
R C Brown, A Witt, J M Fegert, F Keller, M Rassenhofer, P L Plener
Children and adolescents are a vulnerable group to develop post-traumatic stress symptoms after natural or man-made disasters. In the light of increasing numbers of refugees under the age of 18 years worldwide, there is a significant need for effective treatments. This meta-analytic review investigates specific psychosocial treatments for children and adolescents after man-made and natural disasters. In a systematic literature search using MEDLINE, EMBASE and PsycINFO, as well as hand-searching existing reviews and contacting professional associations, 36 studies were identified...
April 11, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28397306/a-review-of-cognitive-impairments-in-children-with-intellectual-disabilities-implications-for-cognitive-behaviour-therapy
#15
Anastasia Hronis, Lynette Roberts, Ian I Kneebone
OBJECTIVE: Nearly half of children with intellectual disability (ID) have comorbid affective disorders. These problems are chronic if left untreated and can significantly impact upon future vocational, educational, and social opportunities. Despite this, there is a paucity of research into effective treatments for this population. Notably, one of the most supported of psychological therapies, cognitive behaviour therapy (CBT), remains largely uninvestigated in children with ID. The current review considers the neuropsychological profile of children and adolescents with mild to moderate ID, with a view to informing how CBT might best be adapted for children and adolescents with ID...
April 11, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28397125/diffuse-alveolar-hemorrhage-in-autoimmune-diseases
#16
REVIEW
Marco Ulises Martínez-Martínez, David Alejandro Herrera-van Oostdam, Carlos Abud-Mendoza
PURPOSE OF REVIEW: The present paper establishes a narrative and analytical review of diffuse alveolar hemorrhage (DAH) in ANCA-associated vasculitis, systemic lupus erythematosus, and antiphospholipid syndrome. RECENT FINDINGS: Recent studies found a frequent association between DAH and infections and systemic lupus erythematosus and its associated factors. Biological therapies like rituximab have demonstrated benefit mainly in patients with ANCA-associated vasculitis...
May 2017: Current Rheumatology Reports
https://www.readbyqxmd.com/read/28394671/the-u-k-nice-2014-guidelines-for-osteoarthritis-of-the-knee-lessons-learned-in-a-narrative-review-addressing-inadvertent-limitations-and-bias
#17
Stephen Birch, Myeong Soo Lee, Nicola Robinson, Terje Alraek
Several systematic reviews suggest that acupuncture is effective for knee osteoarthritis (OA), and furthermore a safe and cost-effective treatment for this condition. A recent clinical practice guideline (CPG) from the National Institute for Health and Care Excellence (NICE), in the United Kingdom, recommended against the use of acupuncture on the grounds that the effect size (ES) in comparison with sham acupuncture is too small. Safety data were not considered in the review, in addition the levels of evidence for acupuncture against other recommended therapies were not compared...
April 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28393705/antithrombotic-therapy-for-transcatheter-valvular-interventions-a-revisit
#18
Shaban Mohammed, Ayman El-Menyar, Haifa Al-Janubi, Adel Shabana, Zaid Alanazi
The optimal antithrombotic therapies for transcatheter aortic valve implantation (TAVI) and MitraClip implantation have not been well established. We conducted a narrative review from currently available studies between January 2002 and May 2016 to highlight the advantages and disadvantages of antithrombotic therapy use in cardiac catheter-based therapeutic techniques. Recently, these techniques have dramatically altered the approach towards valvular heart diseases management. The introduction into clinical practice, of TAVI for severe aortic stenosis and MitraClip for mitral regurgitation, has revolutionized interventional cardiology...
April 6, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28393648/-metacognitive-therapy-and-pharmacotherapy-adapted-to-unaccompanied-refugee-minors
#19
Michael Simons, Britta Pöter
Metacognitive Therapy and Pharmacotherapy - Adapted to Unaccompanied Refugee Minors Unaccompanied refugee minors (URM) present a relatively new challenge for adolescent psychotherapy and psychiatry. The evidence of possible treatment approaches is scarce. This paper presents a pragmatic adaptation of Wells' Metacognitive Therapy (MCT) for this population for the first time. Unlike the established trauma-focused treatment approaches MCT does not aim at prolonged exposure to the trauma narrative. Instead, patients shall learn to leave the distressing thoughts alone and to reduce the perseverating thinking processes (rumination and worrying)...
April 2017: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/28393551/imitation-based-aphasia-therapy-increases-narrative-content-a-case-series
#20
E Susan Duncan, Steven L Small
OBJECTIVE: To test the generalization of an intensive imitation-based aphasia therapy to an unrelated narrative production task. DESIGN: ABA design study (A= no treatment; B= treatment) comparing imitation therapy to a baseline condition (pre-therapy). Participants produced narratives at two pre-therapy and two post-therapy time points. Narratives were analyzed for correct information units to determine the number and percent of communicative words produced. SETTING: A rehabilitation clinic and participants' homes...
April 1, 2017: Clinical Rehabilitation
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