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https://www.readbyqxmd.com/read/27905283/comparative-analysis-of-serum-mineral-levels-and-parasite-load-in-goats-naturally-infected-with-gastrointestinal-nematodes
#1
Serap Ünübol Aypak, Süleyman Aypak, Hüseyin Voyvoda, Gülşen Güven, Evrim Dereli Fidan, Gamze Tosun, Mehmet Gültekin, Emrah Şimşek, Asude Gülçe Güler
OBJECTIVE: This study aimed to investigate the relationship between serum mineral levels and parasite load in Saanen (n=37) and Damascus (n=13) goats, which were all approximately 2 months pregnant and naturally infected with gastrointestinal nematodes. METHODS: To determine parasite concentration individually, fecal samples were taken from each goat, and the eggs per gram (EPG) of feces was detected via a modified McMaster technique. To investigate the possible effects of parasite concentration on serum mineral levels, blood was drawn from the goats and serum calcium, phosphorus, magnesium, iron, copper, zinc, manganese, nickel, and cadmium levels were measured via the ICP-OES technique...
September 2016: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/27902453/environmental-and-occupational-exposure-to-cadmium-in-iran-a-systematic-review
#2
Leila Tavakkoli, Narges Khanjani
INTRODUCTION: Cadmium (Cd) is one of the heavy metals that have negative effects on human health. In Iran, there is no policy to regularly measure Cd in the general population. However, some studies have been performed on special groups and in different cities of Iran. This paper has reviewed these studies and human contamination levels in Iran. METHOD AND MATERIALS: All accessible electronic information resources such as Scientific Information Database (SID), Magiran, IranMedex, PubMed, Web of Knowledge, Google Scholar and Science Direct were searched, with relevant phrases and their Persian translations...
December 1, 2016: Reviews on Environmental Health
https://www.readbyqxmd.com/read/27778365/moderate-prenatal-cadmium-exposure-and-adverse-birth-outcomes-a-role-for-sex-specific-differences
#3
Caroline M Taylor, Jean Golding, Alan M Emond
BACKGROUND/AIM: Studies on the effects of moderate prenatal exposure to cadmium (Cd) on birth outcomes have been contradictory and it has been suggested that effects may be partly masked by sex-specific effects. Our aim was to examine the association of Cd exposure in a large group of pregnant women with birth outcomes in the whole group of participants and by sex. METHODS: Pregnant women were enrolled in the Avon Longitudinal Study of Parents and Children (ALSPAC)...
November 2016: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/27744593/increasing-cacna1c-expression-in-placenta-containing-high-cd-level-an-implication-of-cd-toxicity
#4
Laorrat Phuapittayalert, Phisid Saenganantakarn, Wisa Supanpaiboon, Supaporn Cheunchoojit, Wiphawi Hipkaeo, Natthiya Sakulsak
Cadmium (Cd) has known to produce many adverse effects on organs including placenta. Many essential transporters are involved in Cd transport pathways such as DMT-1, ZIP as well as L-VDCC. Fourteen pregnant women participated and were divided into two groups: high and low Cd-exposed (H-Cd, L-Cd) groups on the basis of their residential areas, Cd concentrations in the blood (B-Cd), urine (U-Cd), and placenta (P-Cd). The results showed that the B-Cd and U-Cd were significantly increased in H-Cd group (p < 0...
October 15, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27707662/dietary-predictors-of-urinary-cadmium-among-pregnant-women-and-children
#5
Meghan Moynihan, Karen E Peterson, Alejandra Cantoral, Peter X K Song, Andrew Jones, Maritsa Solano-González, John D Meeker, Niladri Basu, Martha Maria Téllez-Rojo
BACKGROUND: Cadmium is a toxic metal with modifiable exposure sources including diet. In pregnant women and children, unique dietary habits may contribute to DCd, and the relationship of diet to overall cadmium exposure can depend on specific factors during these transitional time periods. OBJECTIVES: This study aimed to identify and quantify food sources of DCd, describe the distribution of UCd, and determine the relationship of DCd and intake of specific foods with UCd, stratified by maternal smoking history, among pregnant women and children in a well-characterized Mexico City birth cohort...
October 2, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27664951/the-influence-of-maternal-smoking-on-transferrin-sialylation-and-fetal-biometric-parameters
#6
Marta Wrześniak, Małgorzata Królik, Marta Kepinska, Halina Milnerowicz
OBJECTIVES: Transferrin is a glycosylated protein responsible for transporting iron, an essential metal responsible for proper fetal development. Tobacco is a heavily used xenobiotic having a negative impact on the human body and pregnancy outcomes. Aims of this study was to examine the influence of tobacco smoking on transferrin sialic acid residues and their connection with fetal biometric parameters in women with iron-deficiency. METHODS: The study involved 173 samples from pregnant women, smokers and non-smokers, iron deficient and not...
September 15, 2016: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/27567517/placental-biomarkers-of-pah-exposure-and-glutathione-s-transferase-biotransformation-enzymes-in-an-obstetric-population-from-tijuana-baja-california-mexico
#7
Teresa Dodd-Butera, Penelope J E Quintana, Martha Ramirez-Zetina, Ana C Batista-Castro, Maria M Sierra, Carolyn Shaputnic, Maura Garcia-Castillo, Sonja Ingmanson, Stacy Hull
Environmental exposures along the US-Mexico border have the potential to adversely affect the maternal-fetal environment. The purpose of this study was to assess placental biomarkers of environmental exposures in an obstetric population at the California-Baja California border in relation to detoxifying enzymes in the placenta and nutritional status. This study was conducted on consenting, full-term, obstetric patients (n=54), delivering in a hospital in Tijuana, Baja California (BC), Mexico. Placental polyaromatic hydrocarbon (PAH)-DNA adducts were measured in addition to placental glutathione-S-transferase (GST) activity and genotype, maternal serum folate, and maternal and umbilical cord blood lead and cadmium levels...
January 2017: Environmental Research
https://www.readbyqxmd.com/read/27548057/the-influence-of-tobacco-smoke-on-protein-and-metal-levels-in-the-serum-of-women-during-pregnancy
#8
Marta Wrześniak, Marta Kepinska, Małgorzata Królik, Halina Milnerowicz
BACKGROUND: Tobacco smoking by pregnant women has a negative effect on fetal development and increases pregnancy risk by changing the oxidative balance and microelements level. Smoking affects the concentration, structure and function of proteins, potentially leading to various negative effects on pregnancy outcomes. METHODOLOGY/PRINCIPAL FINDINGS: The influence of tobacco smoke on key protein fractions in smoking and non-smoking healthy pregnant women was determined by capillary electrophoresis (CE)...
2016: PloS One
https://www.readbyqxmd.com/read/27540762/maternal-and-fetal-exposure-to-cadmium-lead-manganese-and-mercury-the-mirec-study
#9
Tye E Arbuckle, Chun Lei Liang, Anne-Sophie Morisset, Mandy Fisher, Hope Weiler, Ciprian Mihai Cirtiu, Melissa Legrand, Karelyn Davis, Adrienne S Ettinger, William D Fraser
Given the susceptibility of the fetus to toxicants, it is important to estimate their exposure. Approximately 2000 pregnant women were recruited in 2008-2011 from 10 cities across Canada. Cd, Pb, Mn and total Hg were measured in maternal blood from the 1st and 3rd trimesters, umbilical cord blood, and infant meconium. Nutrient intakes of vitamin D, iron, and calcium (Ca) were assessed using a food frequency questionnaire and a dietary supplement questionnaire. Median concentrations in 1st trimester maternal blood (n = 1938) were 0...
November 2016: Chemosphere
https://www.readbyqxmd.com/read/27511439/cadmium-induced-immune-abnormality-is-a-key-pathogenic-event-in-human-and-rat-models-of-preeclampsia
#10
Qiong Zhang, Yinping Huang, Keke Zhang, Yanjun Huang, Yan Yan, Fan Wang, Jie Wu, Xiao Wang, Zhangye Xu, Yongtao Chen, Xue Cheng, Yong Li, Jinyu Jiao, Duyun Ye
With increased industrial development, cadmium is an increasingly important environmental pollutant. Studies have identified various adverse effects of cadmium on human beings. However, the relationships between cadmium pollution and the pathogenesis of preeclampsia remain elusive. The objective of this study is to explore the effects of cadmium on immune system among preeclamptic patients and rats. The results showed that the cadmium levels in the peripheral blood of preeclamptic patients were significantly higher than those observed in normal pregnancy...
November 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27499053/streptococcus-agalactiae-from-pregnant-women-antibiotic-and-heavy-metal-resistance-mechanisms-and-molecular-typing
#11
B Rojo-Bezares, J M Azcona-Gutiérrez, C Martin, M S Jareño, C Torres, Y Sáenz
We investigated the antibiotic and heavy-metal resistance mechanisms, virulence genes and clonal relationships of macrolide- and/or lincosamide-resistant (M+/-LR) Streptococcus agalactiae (group B Streptococcus, GBS) isolates from pregnant women in La Rioja in Northern Spain, a region with a significant immigrant population. In total 375 GBS isolates were recovered during 2011. About three-quarters of isolates were from European nationals and the remainder distributed among 23 other nationalities. Seventy-five (20%) were classified as M+/-LR strains and 28 (37%) of these were resistant to ⩾3 classes of antibiotics...
November 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27486364/plasma-cadmium-and-zinc-and-their-interrelationship-in-adult-nigerians-potential-health-implications
#12
Emmanuel Ike Ugwuja, Lawrence Ulu Ogbonnaya, Henry Uro-Chukwu, Johnson Akuma Obuna, Emeka Ogiji, Simon Uchenna Ezenkwa
Zinc (an essential trace element) and cadmium (a ubiquitous environmental pollutant with acclaimed toxicity) have been found to occur together in nature, with reported antagonism between the two elements. The present study aimed at determination of plasma levels of zinc (Zn) and cadmium (Cd) and their interrelationship in adult Nigerians. The series comprised adults (n=443) aged ≥18 yrs (mean ± SD 38.4±13.7 yrs), consisting of 117 males, 184 non-pregnant and 140 pregnant females. Sociodemographic data were collected by questionnaire while anthropometrics were determined using standard methods...
June 2015: Interdisciplinary Toxicology
https://www.readbyqxmd.com/read/27469444/long-term-effects-of-perinatal-exposure-to-low-doses-of-cadmium-on-the-prostate-of-adult-male-rats
#13
Viviane P Santana, Évila S Salles, Deborah E Correa, Bianca F Gonçalves, Silvana G Campos, Luiz A Justulin, Antonio F Godinho, Wellerson R Scarano
Developmental toxicity caused by environmental exposure to heavy metals during the perinatal period has raised questions about offspring health. Cadmium (Cd) is an endocrine-disrupting chemical with the potential to interfere with morphogenesis and susceptibility to diseases in reproductive organs. Taking into account that in the rat prostate morphogenesis occurs during the perinatal period, and that pregnant females absorb and retain more dietary Cd than their non-pregnant counterparts, it is important to understand the effects of perinatal Cd exposure on the adult rat prostate...
August 2016: International Journal of Experimental Pathology
https://www.readbyqxmd.com/read/27417525/cadmium-induced-neural-tube-defects-and-fetal-growth-restriction-association-with-disturbance-of-placental-folate-transport
#14
Gui-Bin Zhang, Hua Wang, Jun Hu, Min-Yin Guo, Ying Wang, Yan Zhou, Zhen Yu, Lin Fu, Yuan-Hua Chen, De-Xiang Xu
Previous studies found that maternal Cd exposure on gestational day (GD)9 caused forelimb ectrodactyly and tail deformity, the characteristic malformations. The aim of the present study was to investigate whether maternal Cd exposure on GD8 induces fetal neural tube defects (NTDs). Pregnant mice were intraperitoneally injected with CdCl2 (2.5 or 5.0mg/kg) on GD8. Neither forelimb ectrodactyly nor tail deformity was observed in mice injected with CdCl2 on GD8. Instead, maternal Cd exposure on GD8 resulted in the incidence of NTDs...
September 1, 2016: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/27399148/acute-toxicity-of-quantum-dots-on-late-pregnancy-mice-effects-of-nanoscale-size-and-surface-coating
#15
Wanyi Zhang, Lin Yang, Huijuan Kuang, Pengfei Yang, Zoraida P Aguilar, Andrew Wang, Fen Fu, Hengyi Xu
In this study, the effects of cadmium containing QDs (such as CdSe/ZnS and CdSe QDs) and bulk CdCl2 in pregnant mice, their fetuses, and the pregnancy outcomes were investigated. It was shown that although the QDs and bulk CdCl2 were effectively blocked by the placental barrier, the damage on the placenta caused by CdSe QDs still led to fetus malformation, while the mice in CdSe/ZnS QDs treatment group exhibited slightly hampered growth but showed no significant abnormalities. Moreover, the Cd contents in the placenta and the uterus of CdSe QDs and CdSe/ZnS QDs treatment groups showed significantly higher than the CdCl2 treated group which indicated that the nanoscale size of the QDs allowed relative ease of entry into the gestation tissues...
November 15, 2016: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/27319394/maternal-cadmium-exposure-reduces-placental-zinc-transport-and-induces-fetal-growth-restriction-in-mice
#16
Hua Wang, Ying Wang, Qing-Li Bo, Yan-Li Ji, Lu Liu, Yong-Fang Hu, Yuan-Hua Chen, Jun Zhang, Ling-Li Zhao, De-Xiang Xu
Cadmium (Cd) is linked with increased risk of fetal growth restriction (FGR). Nevertheless, the mechanism remains unknown. This study established a mouse model of Cd-induced FGR through two exposure methods. Pregnant mice were either administered with CdCl2 (5, 50 and 250ppm) throughout pregnancy through drinking water or intraperitoneally injected with CdCl2 (4.5mg/kg) on GD9. As expected, fetal weight and crown-rump length were reduced in a gender-independent manner. Interestingly, Mt1 and Mt2, two metallothionein genes, were up-regulated in maternal liver...
August 2016: Reproductive Toxicology
https://www.readbyqxmd.com/read/27289180/maternal-urinary-cadmium-concentrations-in-relation-to-preterm-birth-in-the-healthy-baby-cohort-study-in-china
#17
Jie Yang, Wenqian Huo, Bin Zhang, Tongzhang Zheng, Yuanyuan Li, Xinyun Pan, Wenyu Liu, Huailong Chang, Minmin Jiang, Aifen Zhou, Zhengmin Qian, Yanjian Wan, Wei Xia, Shunqing Xu
BACKGROUND: Prenatal cadmium (Cd) exposure has been associated with adverse birth outcomes, but the findings of previous studies are inconsistent. The aim of this study was to evaluate the association between prenatal Cd exposure and birth outcomes. METHODS: This study was conducted in 5364 pregnant women with a live singleton birth, who were recruited between September 2012 and October 2014 in the Healthy Baby Cohort (HBC) in Wuhan, China. Gestational age (in days) was estimated using both the woman's last menstrual period (LMP) and ultrasound data...
September 2016: Environment International
https://www.readbyqxmd.com/read/27190399/time-to-pregnancy-associated-with-couples-use-of-tobacco-products
#18
Katherine J Sapra, Dana B Barr, José M Maisog, Rajeshwari Sundaram, Germaine M Buck Louis
INTRODUCTION: Previous studies suggest female smoking increases time-to-pregnancy (TTP), a couple-dependent reproductive outcome, while associations with male smoking are more ambiguous. Furthermore, despite small increases in smokeless tobacco use in the United States, no prior study has evaluated TTP among smokeless tobacco users. METHODS: Using population-based sampling in 16 counties in Michigan and Texas, 501 couples discontinuing contraception to become pregnant were followed until positive pregnancy test or 12 months of trying...
November 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27129315/associations-of-maternal-urinary-cadmium-with-trimester-specific-blood-pressure-in-pregnancy-role-of-dietary-intake-of-micronutrients
#19
C Osorio-Yañez, B Gelaye, R S Miller, D A Enquobahrie, A A Baccarelli, C Qiu, M A Williams
Previous studies revealed associations of urinary Cd (U-Cd), a chronic Cd exposure biomarker, with blood pressure (BP) in non-pregnant adults. However, the evidence regarding trimester-specific blood pressure in pregnancy and U-Cd and effect modification by dietary intake of micronutrients is scarce. We randomly selected 653 women from the Omega Study cohort. U-Cd was quantified by inductively coupled plasma mass spectrometry. Trimester-specific, systolic (SBP) and diastolic blood pressure (DBP) were determined employing standard protocols and mean arterial pressure (MAP) was also calculated...
April 29, 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/27049579/environmental-cadmium-and-lead-exposure-and-anti-m%C3%A3-llerian-hormone-in-pregnant-women
#20
P S Christensen, J P Bonde, L Bungum, A Giwercman, G Toft, B A G Jönsson, I O Specht
BACKGROUND: Anti-Müllerian Hormone (AMH) has been suggested as a marker for ovarian function. Cadmium and lead have been suggested to reduce female fecundity. In this study we aimed to investigate whether environmental exposure to cadmium and lead was associated with alterations in serum-AMH. MATERIALS AND METHOD: The associations between serum-AMH and whole blood cadmium or lead were investigated by general linear models in a population-based sample of 117 pregnant women...
June 2016: Reproductive Toxicology
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