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https://www.readbyqxmd.com/read/28545607/dynamically-weighted-evolutionary-ordinal-neural-network-for-solving-an-imbalanced-liver-transplantation-problem
#1
Manuel Dorado-Moreno, María Pérez-Ortiz, Pedro A Gutiérrez, Rubén Ciria, Javier Briceño, César Hervás-Martínez
OBJECTIVE: Create an efficient decision-support model to assist medical experts in the process of organ allocation in liver transplantation. The mathematical model proposed here uses different sources of information to predict the probability of organ survival at different thresholds for each donor-recipient pair considered. Currently, this decision is mainly based on the Model for End-stage Liver Disease, which depends only on the severity of the recipient and obviates donor-recipient compatibility...
March 2017: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/28535616/drug-induced-osteonecrosis-of-the-jaw-the-state-of-the-art
#2
A Fassio, F Bertoldo, L Idolazzi, O Viapiana, M Rossini, D Gatti
Osteonecrosis of the jaw (ONJ) is a rare adverse event of antiresorptive drugs such as bisphosphonates (BP) and denosumab (DMAb). The diagnosis of ONJ is considered in cases where exposed bone in the maxillofacial region does not heal within 8 weeks in a patient previously treated with an antiresorptive agent. In patients with osteoporosis, ONJ is reported as a very rare adverse event while in oncologic patients with bone metastases or malignant hypercalcemia the incidence is significantly higher (up to the 1-10% of the patients)...
May 22, 2017: Reumatismo
https://www.readbyqxmd.com/read/28529680/-beyond-saving-lives-current-perspectives-of-interventional-radiology-in-trauma
#3
REVIEW
Anuradha Singh, Atin Kumar, Pawan Kumar, Subodh Kumar, Shivanand Gamanagatti
Interventional radiology (IR) has become an integral part in the management of traumatic injuries. There is an ever-increasing role of IR in traumatic injuries of solid abdominal organs, pelvic and peripheral arteries to control active bleeding by therapeutic embolization or vascular reconstruction using stent grafts. Traditionally, these endovascular treatments have been offered to hemodynamically stable patients. However, in recent times endovascular approach has become preferable to surgery even in hemodynamically unstable patients with injury of surgically difficult-to-access sites...
April 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28529430/mechanical-behavior-and-wall-remodeling-of-blood-vessels-under-axial-twist
#4
Han Hai-Chao, Liu Qin, Jiang Zong-Lai
Blood vessels are often subjected to axial torsion (or twist) due to body movement or surgery. However, there are few studies on blood vessel under twist. This review first summarizes the clinical observation on the twist of blood vessels and then presents what we know about the mechanical behaviors of blood vessel under twist, including the constitutive models. The state of art researches on the remodeling of blood vessels under twist via ex vivo organ culture, in vivo animal experiments, and mathematical model simulations are further discussed...
August 2016: Yi Yong Sheng Wu Li Xue
https://www.readbyqxmd.com/read/28528136/the-management-of-the-acute-ischemic-priapism-a-state-of-the-art-review
#5
M Falcone, A Gillo, M Capece, A Raheem, D Ralph, G Garaffa
OBJECTIVE: To review the current literature on early penile prosthesis implantation in patients with refractory ischemic priapism (IP). ACQUISITION OF EVIDENCE: A systematic search for the terms "penile prosthesis", "priapism", "impotence", "fibrosis", "downsized prosthesis cylinders", and "patient satisfaction" has been carried out in PubMed, EMBASE, Cochrane, SCOPUS and Science Citation Index databases. SYNTHESIS OF EVIDENCE: Cavernosal tissue damage in IP is time related...
May 17, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28504955/three-dimensional-intravascular-reconstruction-techniques-based-on-intravascular-ultrasound-a-technical-review
#6
Chaoyang Shi, Xiongbiao Luo, Jin Guo, Zoran Najdovski, Toshio Fukuda, Hongliang Ren
Intravascular ultrasound (IVUS) imaging provides two-dimensional (2D) real-time luminal and transmural cross-sectional images of intravascular vessels with detailed pathological information. It has offered significant advantages in terms of diagnosis and guidance and has been increasingly introduced from coronary interventions into more generalized endovascular surgery. However, IVUS itself does not provide spatial pose information for its generated images, making it difficult to construct a 3D intravascular visualization...
May 12, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28499298/-cochlear-implant-state-of-the-art
#7
Thomas Lenarz
Cochlear implants are the treatment of choice for the auditory rehabilitation of patients with sensory deafness. They restore the missing function of inner hair cells by transforming the acoustic signal into electrical stimuli for activation of auditory nerve fibers. Due to the very fast technology development cochlear implants provide open-set speech understanding in the majority of patients including the use of the telephone. Children can achieve a near to normal speech and language development provided their deafness is detected early after onset and implantation is performed quickly thereafter...
April 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28499294/h%C3%A3-rger%C3%A3-te-indikationen-technologie-anpassung-und-qualit%C3%A3-tskontrolle
#8
Ulrich Hoppe, Gerhard Hesse
Hearing loss can be caused by a number of different pathological conditions. Some of them can be successfully treated, mainly by surgery, depending on the individual's disease process. However, the treatment of chronic sensorineural hearing loss with damaged cochlear structures usually needs hearing rehabilitation by means of technical amplification. During the last 2 decades tremendous improvements in hearing aid technology led to a higher quality in the hearing rehabilitation process. For example, due to sophisticated signal processing the acoustic feedback path could be reduced and hence open fitting options are available for even more subjects...
April 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28482198/slice-to-volume-medical-image-registration-a-survey
#9
Enzo Ferrante, Nikos Paragios
During the last decades, the research community of medical imaging has witnessed continuous advances in image registration methods, which pushed the limits of the state-of-the-art and enabled the development of novel medical procedures. A particular type of image registration problem, known as slice-to-volume registration, played a fundamental role in areas like image guided surgeries and volumetric image reconstruction. However, to date, and despite the extensive literature available on this topic, no survey has been written to discuss this challenging problem...
April 28, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28479238/challenging-the-myth-transvaginal-mesh-is-not-associated-with-carcinogenesis
#10
Bilal Chughtai, Art Sedrakyan, Jialin Mao, Dominique Thomas, Karyn S Eilber, J Quentin Clemens, Jennifer T Anger
PURPOSE: We sought to determine if there was a potential link between synthetic polypropylene mesh implantation for transvaginal pelvic organ prolapse (POP) and stress urinary incontinence (SUI) and carcinogenesis using statewide administrative data. MATERIALS AND METHODS: Adult women undergoing transvaginal surgery for POP or SUI) with mesh between January 2008 and December 2009 in New York State were identified using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) procedure codes and Current Procedural Terminology Coding System, Fourth Edition (CPT-4) codes...
May 4, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28477204/minimally-invasive-vs-open-nephrectomy-in-the-modern-era-does-approach-matter
#11
David M Golombos, Bilal Chughtai, Quoc-Dien Trinh, Dominique Thomas, Jialin Mao, Alexis Te, Padraic O'Malley, Douglas S Scherr, Joseph Del Pizzo, Jim C Hu, Art Sedrakyan
PURPOSE: To evaluate if the widespread adoption of a minimally invasive approach to radical nephrectomy has affected short- and long-term patient outcomes in the modern era. METHODS: A retrospective cohort study of patients who underwent radical nephrectomy from 2001 to 2012 was conducted using the US National Cancer Institute Surveillance Epidemiology and End Results (SEER) Program and Medicare insurance program database. Patients who underwent open surgery were compared to those who underwent minimally invasive surgery using propensity score matching...
May 5, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28448381/higher-surgical-morbidity-for-ulcerative-colitis-patients-in-the-era-of-biologics
#12
Jonathan S Abelson, Fabrizio Michelassi, Jialin Mao, Art Sedrakyan, Heather Yeo
OBJECTIVE: To investigate differences in surgical approach and postoperative outcomes for patients with ulcerative colitis (UC) before and after the introduction of biologic therapy. BACKGROUND: Biologic use has dramatically increased since Food and Drug Administration approval of infliximab. Studies conflict as to the effect of these agents on surgical outcomes with some demonstrating worse surgical outcomes whereas others have found no difference. METHODS: We used an administrative, all-payer, all-age group database located in New York State...
April 26, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28442772/discriminative-and-distinct-phenotyping-by-constrained-tensor-factorization
#13
Yejin Kim, Robert El-Kareh, Jimeng Sun, Hwanjo Yu, Xiaoqian Jiang
Adoption of Electronic Health Record (EHR) systems has led to collection of massive healthcare data, which creates oppor- tunities and challenges to study them. Computational phenotyping offers a promising way to convert the sparse and complex data into meaningful concepts that are interpretable to healthcare givers to make use of them. We propose a novel su- pervised nonnegative tensor factorization methodology that derives discriminative and distinct phenotypes. We represented co-occurrence of diagnoses and prescriptions in EHRs as a third-order tensor, and decomposed it using the CP algorithm...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28441307/90-day-readmission-after-lumbar-spinal-fusion-surgery-in-new-york-state-between-2005-and-2014-a-10-year-analysis-of-a-statewide-cohort
#14
Ali A Baaj, Gernot Lang, Wei-Chun Hsu, Mauricio J Avila, Jialin Mao, Art Sedrakyan
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To assess 90-day readmission and evaluate risk factors associated with readmission after lumbar fusion in New York State. SUMMARY OF BACKGROUND DATA: Readmission is becoming an important metric for quality and efficiency of healthcare. Readmission and its predictors following spine surgery are overall poorly understood and limited evidence is available specifically in lumbar fusion. METHODS: The New York Statewide Planning and Research Cooperative System (SPACRS) was utilized to capture patients undergoing lumbar fusion from 2005-2014...
April 24, 2017: Spine
https://www.readbyqxmd.com/read/28427542/recurrent-respiratory-papillomatosis-a-state-of-the-art-review
#15
REVIEW
Helena Ribeiro Fortes, Felipe Mussi von Ranke, Dante Luiz Escuissato, Cesar Augusto Araujo Neto, Gláucia Zanetti, Bruno Hochhegger, Carolina Althoff Souza, Edson Marchiori
Recurrent respiratory papillomatosis (RRP) is a benign disease of the upper aero-digestive tract caused by human papillomavirus (HPV) infection, which affects children and young adults. The aim of this review is to describe the main etiological, epidemiological, clinical, diagnostic, and treatment aspects of RRP. Most infections in children occur at birth, during passage through the birth canals of contaminated mothers. In adults, HPV is transmitted sexually. Papillomas usually appear as exophytic nodules, primarily in the larynx, but occasionally involving the nasopharynx, tracheobronchial tree, and pulmonary parenchyma...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28422876/low-complication-rate-of-elastic-stable-intramedullary-nailing-esin-of-pediatric-forearm-fractures-a-retrospective-study-of-202-cases
#16
Christiane Kruppa, Pamela Bunge, Thomas A Schildhauer, Marcel Dudda
Elastic stable intramedullary nailing (ESIN) has been established as state of the art treatment for forearm fractures in children, if operative stabilization is required. Their use has been expanded to single bone shaft fractures, and also more complex injuries such as Monteggia fractures or Monteggia-like lesions. A wide range of complications has been reported in the literature, up to 70% in certain investigations. The purpose of this study was to assess the complication rate after ESIN treatment of forearm fractures in children and adolescents in a representative cohort of patients from a level 1 trauma center in Germany...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28393540/microfracture-state-of-the-art-in-cartilage-surgery
#17
Florian Frehner, Jan P Benthien
Objective This study is a literature review from 2010 to 2014 concerning the quality of evidence in clinical trials about microfracture in attempt to repair articular cartilage. We have decided to focus on microfracturing, since this seems to be the best documented technique. Interest in evaluation of publication quality has risen in orthopaedic sports medicine recently. Therefore, we think it is necessary to evaluate recent clinical trials being rated for their evidence-based medicine (EBM) quality. We also compared the mean impact factor of the journals publishing the different studies as an indicator of the study's citation and evaluated for a change over the studied time frame...
April 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28393063/neuropsychological-and-psychiatric-outcomes-in-dextro-transposition-of-the-great-arteries-across-the-lifespan-a-state-of-the-art-review
#18
REVIEW
Leila Kasmi, Damien Bonnet, Michèle Montreuil, David Kalfa, Nikoletta Geronikola, David C Bellinger, Johanna Calderon
Advances in prenatal diagnosis, perioperative management, and postoperative care have dramatically increased the population of survivors of neonatal and infant heart surgery. The high survival rate of these patients into adulthood has exposed the alarming prevalence of long-term neuropsychological and psychiatric morbidities. Dextro-transposition of the great arteries (d-TGA) is one of the most extensively studied cyanotic congenital heart defect (CHD) with regard to neurodevelopmental outcomes. Landmark studies have described a common neurodevelopmental and behavioral phenotype associated with d-TGA...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28391577/neoadjuvant-treatment-in-pancreatic-cancer-evidence-based-medicine-a-systematic-review-and-meta-analysis
#19
REVIEW
Francesco D'Angelo, Laura Antolino, Alessio Farcomeni, Dario Sirimarco, Andrea Kazemi Nava, Martina De Siena, Niccolò Petrucciani, Giuseppe Nigri, Stefano Valabrega, Paolo Aurello, Giovanni Ramacciato
Neoadjuvant treatment in non-metastatic pancreatic cancer (PaC) has the theoretical advantages of downstaging the tumor, sterilizing any present systemic undetectable disease, selecting patients for surgery and administering therapy to each patient. The aim of this systematic review is to analyze the state of the art on neoadjuvant protocols for non-metastatic PaC. A literature search over the last 10 years was conducted, and papers had to be focused on resectable, borderline resectable (BLR) or locally advanced (LA) histo- or cytologically proven PaC; to be prospective studies or prospectively collected databases; to report percentage of protocol achievement and survival data at least in an intention-to-treat (ITT) analysis...
May 2017: Medical Oncology
https://www.readbyqxmd.com/read/28386298/highlights-from-the-36th-european-society-of-surgical-oncology-congress-esso-36-14-16-september-2016-kracow-poland-optimising-european-cancer-surgery
#20
Danuta Lichosik
The ESSO Congress is the event for all surgeons with an interest in surgical oncology. The congress is a gathering for the surgical oncology community from all around the world to meet and gain an insight into state-of-the-art technology, latest healthcare services, and solutions within their field. The ESSO 36 congress gathered over 750 participants from 58 countries. With over 100 speakers, the scientific programme featured 18 scientific symposia including a joint symposium with the American Society of Surgical Oncology (SSO), 6 multidisciplinary sessions including joint sessions with CIRSE (Cardiovascular and Interventional Radiological Society of Europe) and JCOG (Japanese Clinical Oncology Group), 8 meet-the-expert sessions, 5 debates, 13 proffered paper sessions, and 2 video sessions...
2017: Ecancermedicalscience
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