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https://www.readbyqxmd.com/read/28105610/antithyroid-drug-induced-agranulocytosis-state-of-the-art-on-diagnosis-and-management
#1
Nuno Vicente, Luís Cardoso, Luísa Barros, Francisco Carrilho
Agranulocytosis is a rare but serious complication of antithyroid drug therapy, and an up-to-date understanding of this topic is important. Both direct toxicity and immune-mediated responses have been described as possible mechanisms. Some major susceptibility loci have recently been identified, which may lead the diagnosis of agranulocytosis into a genomic era. Onset is acute and patients present with symptoms and signs of infection together with high fever. Clinical suspicion is pivotal and should prompt blood sampling...
January 19, 2017: Drugs in R&D
https://www.readbyqxmd.com/read/28074785/deformable-registration-of-ct-and-cone-beam-ct-with-local-intensity-matching
#2
Seyoun Park, William Plishker, Harry Quon, John Wong, Raj Shekhar, Junghoon Lee
Cone-beam CT (CBCT) is a widely used intra-operative imaging modality in image-guided radiotherapy and surgery. A short scan followed by a filtered-backprojection is typically used for CBCT reconstruction. While data on the mid-plane (plane of source-detector rotation) is complete, off-mid-planes undergo different information deficiency and the computed reconstructions are approximate. This causes different reconstruction artifacts at off-mid-planes depending on slice locations, and therefore impedes accurate registration between CT and CBCT...
February 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28060703/a-dataset-and-benchmarks-for-segmentation-and-recognition-of-gestures-in-robotic-surgery
#3
Narges Ahmidi, Lingling Tao, Shahin Sefati, Yixin Gao, Colin Lea, Benjamin Bejar, Luca Zappella, Sanjeev Khudanpur, Rene Vidal, Gregory D Hager
OBJECTIVE: State-of-the-art techniques for surgical data analysis report promising results for automated skill assessment and action recognition. The contributions of many of these techniques, however, are limited to study-specific data and validation metrics, making assessment of progress across the field extremely challenging. METHODS: In this paper, we address two major problems for surgical data analysis: (1) lack of uniform shared datasets and benchmarks and (2) lack of consistent validation processes...
January 4, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28059854/perforator-phase-contrast-angiography-of-deep-inferior-epigastric-perforators-a-better-preoperative-imaging-tool-for-flap-surgery-than-computed-tomographic-angiography
#4
Xiangyu Yang, Michael J Miller, Harry T Friel, Allison Slijepcevic, Michael V Knopp
OBJECTIVE: The aim of this study was to demonstrate the feasibility of in vivo perforator visualization by a newly proposed magnetic resonance-based perforator phase contrast angiography (pPCA) technique for deep inferior epigastric perforator (DIEP) flap surgery and to prospectively compare its image quality and clinical value with computed tomographic angiography (CTA), the state-of-the-art perforator imaging technique. MATERIALS AND METHODS: Institutional review board approval and informed consent were obtained...
January 4, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28054328/magnetoencephalography-and-new-imaging-modalities-in-epilepsy
#5
REVIEW
Jessica Falco-Walter, Christian Owen, Mishu Sharma, Christopher Reggi, Mandy Yu, Travis R Stoub, Michael A Stein
The success of epilepsy surgery is highly dependent on correctly identifying the entire epileptogenic region. Current state-of-the-art for localizing the extent of surgically amenable areas involves combining high resolution three-dimensional magnetic resonance imaging (MRI) with electroencephalography (EEG) and magnetoencephalography (MEG) source modeling of interictal epileptiform activity. Coupling these techniques with newer quantitative structural MRI techniques, such as cortical thickness measurements, however, may improve the extent to which the abnormal epileptogenic region can be visualized...
January 4, 2017: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/28049604/evaluating-tumour-after-care-in-oral-squamous-cell-carcinoma-insights-into-patients-health-related-quality-of-life
#6
Oliver Bissinger, Andrea Rau, Steffen Koerdt, Klaus-Dietrich Wolff, Marco Rainer Kesting, Carolin Götz
INTRODUCTION: Tumour aftercare (tac) is an essential tool in oncology. The main aim of these follow ups is to diagnose recurrence and second tumours from the beginning. Tac appointments can create a special environment for patients' further concerns. The purpose of the current study was to evaluate tac of patients diagnosed with OSCC and to investigate their health related quality of life (hrql). MATERIAL AND METHODS: A German questionnaire was created by two maxillo-facial surgeons with several years of tac experience...
December 9, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28048500/we-h-202-04-advanced-medical-image-registration-techniques
#7
G Christensen
: Deformable image registration has now been commercially available for several years, with solid performance in a number of sites and for several applications including contour and dose mapping. However, more complex applications have arisen, such as assessing response to radiation therapy over time, registering images pre- and post-surgery, and auto-segmentation from atlases. These applications require innovative registration algorithms to achieve accurate alignment. The goal of this session is to highlight emerging registration technology and these new applications...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048394/we-h-202-00-session-in-memory-of-jean-pouliot-next-generation-deformable-image-registration
#8
Geoffrey Hugo
: Deformable image registration has now been commercially available for several years, with solid performance in a number of sites and for several applications including contour and dose mapping. However, more complex applications have arisen, such as assessing response to radiation therapy over time, registering images pre- and post-surgery, and auto-segmentation from atlases. These applications require innovative registration algorithms to achieve accurate alignment. The goal of this session is to highlight emerging registration technology and these new applications...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047749/we-h-202-01-memorial-introduction
#9
N Kirby
: Deformable image registration has now been commercially available for several years, with solid performance in a number of sites and for several applications including contour and dose mapping. However, more complex applications have arisen, such as assessing response to radiation therapy over time, registering images pre- and post-surgery, and auto-segmentation from atlases. These applications require innovative registration algorithms to achieve accurate alignment. The goal of this session is to highlight emerging registration technology and these new applications...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047096/we-h-202-02-biomechanical-modeling-of-anatomical-response-over-the-course-of-therapy
#10
K Brock
: Deformable image registration has now been commercially available for several years, with solid performance in a number of sites and for several applications including contour and dose mapping. However, more complex applications have arisen, such as assessing response to radiation therapy over time, registering images pre- and post-surgery, and auto-segmentation from atlases. These applications require innovative registration algorithms to achieve accurate alignment. The goal of this session is to highlight emerging registration technology and these new applications...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046433/we-h-202-03-accounting-for-large-geometric-changes-during-radiotherapy
#11
G Hugo
: Deformable image registration has now been commercially available for several years, with solid performance in a number of sites and for several applications including contour and dose mapping. However, more complex applications have arisen, such as assessing response to radiation therapy over time, registering images pre- and post-surgery, and auto-segmentation from atlases. These applications require innovative registration algorithms to achieve accurate alignment. The goal of this session is to highlight emerging registration technology and these new applications...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28034649/is-vaginal-mesh-a-stimulus-of-autoimmune-disease
#12
Bilal Chughtai, Art Sedrakyan, Jialin Mao, Karyn S Eilber, Jennifer T Anger, J Quentin Clemens
OBJECTIVE: To investigate a potential link between the development of systemic/ autoimmune disorders and synthetic polypropylene mesh repairs. METHODS: New York State Department of Health Statewide Planning and Research Cooperative System data was utilized to conduct this retrospective cohort study. Adult women undergoing surgery for pelvic organ prolapse (POP) with vaginally implanted mesh between January 2008 and December 2009 in inpatient and ambulatory surgery settings in New York State were identified...
December 26, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28033200/lvad-outflow-graft-angle-and-thrombosis-risk
#13
Alberto Aliseda, Venkat Keshav Chivukula, Patrick Mcgah, Anthony R Prisco, Jennifer A Beckman, Guilherme J M Garcia, Nahush A Mokadam, Claudius Mahr
This study quantifies thrombogenic potential (TP) of a wide range of left ventricular assist device (LVAD) outflow graft anastomosis angles through state-of-the-art techniques: 3D imaged-based patient-specific models created via virtual surgery and unsteady computational fluid dynamics with Lagrangian particle tracking. This study aims at clarifying the influence of a single parameter (outflow graft angle) on the thrombogenesis associated with flow patterns in the aortic root after LVAD implantation. This is an important and poorly-understood aspect of LVAD therapy, because several studies have shown strong inter and intrapatient thrombogenic variability and current LVAD implantation strategies do not incorporate outflow graft angle optimization...
January 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28026747/joint-dictionary-learning-based-non-negative-matrix-factorization-for-voice-conversion-to-improve-speech-intelligibility-after-oral-surgery
#14
Szu-Wei Fu, Pei-Chun Li, Ying-Hui Lai, Cheng-Chien Yang, Li-Chun Hsieh, Yu Tsao
OBJECTIVE: This paper focuses on machine learning based voice conversion (VC) techniques for improving the speech intelligibility of surgical patients who have had parts of their articulators removed. Because of the removal of parts of the articulator, a patient's speech may be distorted and difficult to understand. To overcome this problem, VC methods can be applied to convert the distorted speech such that it is clear and more intelligible. To design an effective VC method, two key points must be considered: (1) the amount of training data may be limited (because speaking for a long time is usually difficult for post-operative patients); (2) rapid conversion is desirable (for better communication)...
December 23, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28024773/comprehensive-treatment-approach-for-condylar-hyperplasia-and-mandibular-crowding-with-custom-lingual-braces-and-2-jaw-surgery
#15
Panagiotis G Kyteas, W Stuart McKenzie, Peter D Waite, Chung H Kau
We report on the successful treatment of a 32-year-old woman with condylar hyperplasia and severe mandibular crowding. In addition, her maxilla was canted to the right, her mandibular midline and chin point deviated to the left, and her maxillary canines were missing. The treatment plan included (1) aligning and leveling the teeth in both arches, (2) correcting overbite and overjet, (3) performing LeFort I osteotomy and bilateral split osteotomies, and (4) correcting the malocclusion postsurgically. The orthodontic treatment was performed with custom lingual braces and clear brackets, and virtual surgical planning techniques were used to plan the orthognathic surgery...
January 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28009740/surgeon-annual-and-cumulative-volumes-predict-early-postoperative-outcomes-after-rectal-cancer-resection
#16
Heather L Yeo, Jonathan S Abelson, Jialin Mao, Paul R A O'Mahoney, Jeffrey W Milsom, Art Sedrakyan
OBJECTIVE: To determine if 5-year surgeon cumulative and annual volumes predict improved early postoperative outcomes in patients with rectal cancer. BACKGROUND: Operative experience has been shown to effect surgical outcomes. The differential role of cumulative versus annual volume has not yet been explored for rectal surgery. METHODS: The Statewide Planning and Research Cooperative System database was used to capture patients undergoing surgery in New York State from 2000 to 2013...
January 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28009144/robot-assisted-lymphadenectomy-in-urology-pelvic-retroperitoneal-and-inguinal
#17
Giovannalberto Pini, Surena F Matin, Nazareno Suardi, Mihir Desai, Inderbir Gill, James Porter, Robert J Stein, Rene Sotelo, Franco Gaboardi, Francesco Porpiglia
Lymph node dissection represents an essential surgical step in the treatment of the most commonly treated urological cancers. The introduction of robotic surgery has lead to the possibility of treating these diseases with a minimally invasive surgical approach, but the surgical principles of open surgery need to be carefully respected in order to achieve comparable oncological results. Therefore, the robotic approach to urological cancers must include a carefully performed lymph node dissection when indicated...
February 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28005765/functional-reconstruction-in-mandibular-avulsion-injuries
#18
Yoav Leiser, Dekel Shilo, Amir Wolff, Adi Rachmiel
The present report describes the planning and surgery as well as pitfalls and management of a patient with a near total mandibular avulsion injury that was rehabilitated using three-dimensional (3D) laser printing of a titanium lower jaw. Laser-sintering involves zapping layers of powdered metal to recreate a 3D implantable skeletal defect. The process involves using either mirror imaging of the unaffected side or using archival image database of healthy individuals. A 25-year-old man presented with a gunshot injury that left him with a near total avulsed mandible...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28005762/jaw-in-a-day-state-of-the-art-in-maxillary-reconstruction
#19
Christopher M Runyan, Vishal Sharma, David A Staffenberg, Jamie P Levine, Lawrence E Brecht, Leonard H Wexler, David L Hirsch
BACKGROUND: Reconstruction of maxillary defects following tumor extirpation is challenging because of combined aesthetic and functional roles of the maxilla. One-stage reconstruction combining osseous free flaps with immediate osseointegrated implants are becoming the standard for mandibular defects, and have similar potential for maxillary reconstruction. METHODS: A woman with maxillary Ewing sarcoma successfully treated at age 9 with neoadjuvant chemotherapy, right hemimaxillectomy, and obturator prosthetic reconstruction presented for definitive reconstruction, complaining of poor obturator fit, and hypernasality...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28000275/current-state-of-the-art-of-computer-guided-implant-surgery
#20
REVIEW
Jan D'haese, Johan Ackhurst, Daniel Wismeijer, Hugo De Bruyn, Ali Tahmaseb
The invention of computerized axial tomography (now known as computerized tomography) and developments of interactive software to allow virtual planning, with the aim to guide the surgery precisely toward a specific target, has dramatically improved general, as well as oral, surgery. Virtual dental implant planning allows for a prosthetically driven approach, resulting in the best possible design of the prosthesis, better esthetics, optimized occlusion and loading. This approach has also changed the surgical paradigm of using extensive flaps to obtain a proper view of the surgical area because flapless implant surgery, with or without immediate loading, has become more predictable...
February 2017: Periodontology 2000
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