keyword
MENU ▼
Read by QxMD icon Read
search

reactive hyperemia index

keyword
https://www.readbyqxmd.com/read/28794106/flow-mediated-dilation-and-peripheral-arterial-tonometry-are-disturbed-in-pre-eclampsia-and-reflect-different-aspects-of-endothelial-function
#1
Dominique Mannaerts, Ellen Faes, Inge Goovaerts, Tibor Stoop, Jerome Cornette, Wilfried Jozef Gyselaers, Marc E A Spaanderman, Emeline M Van Craenenbroeck, Yves Jacquemyn
BACKGROUND: Endothelial function and arterial stiffness are known to be altered in pre-eclamptic pregnancies. Previous studies have shown conflicting results regarding the best technique for assessing vascular function in pregnancy. In this study, we made a comprehensive evaluation of in vivo vascular function (including flow-mediated dilatation (FMD), peripheral arterial tonometry (PAT), and arterial stiffness) in pre-eclamptic patients and compared them to normal pregnancies. In addition, we assessed the relation between vascular function and systemic inflammation...
August 9, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28768922/preoperative-assessment-of-endothelial-function-for-prediction-of-adverse-events-after-cardiovascular-surgery
#2
Yuichi Saito, Hideki Kitahara, Goro Matsumiya, Yoshio Kobayashi
BACKGROUND: Cardiovascular surgery is one of the highest risk procedures in the field of surgery. Preoperative assessment of endothelial function has been reported as useful for predicting postoperative adverse events (AEs). The aim of this study was to investigate the relationship between endothelial function assessed by reactive hyperemia index (RHI) and AEs after cardiovascular surgery.Methods and Results:A prospective observational study of 197 patients who underwent cardiovascular surgery was conducted...
August 3, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28750006/the-impact-of-repetitive-long-duration-water-immersion-on-vascular-function
#3
Erin E Simmons, Elizabeth R Bergeron, John P Florian
While physiological responses to water immersion (WI) are well-studied, the vascular responses after WI are less understood. Fifteen male subjects performed six-hour resting thermoneutral water immersions (WI) at 1.35 atmospheres absolute for four consecutive days, with follow-up on the fifth day. Measurements included peripheral endothelial function and augmentation index (PAT, peripheral arterial tonometry), beat-to-beat blood pressure (BP, photoplethysmography), heart rate (HR), and plasma volume (PV) calculated from changes in hemoglobin and hematocrit...
2017: PloS One
https://www.readbyqxmd.com/read/28740456/carotid-artery-stiffness-digital-endothelial-function-and-coronary-calcium-in-patients-with-essential-thrombocytosis-free-of-overt-atherosclerotic-disease
#4
Matjaz Vrtovec, Ajda Anzic, Irena Preloznik Zupan, Katja Zaletel, Ales Blinc
BACKGROUND: Patients with myeloproliferative neoplasms (MPNs) are at increased risk for atherothrombotic events. Our aim was to determine if patients with essential thrombocytosis (ET), a subtype of MPNs, free of symptomatic atherosclerosis, have greater carotid artery stiffness, worse endothelial function, greater coronary calcium and carotid plaque burden than control subjects. PATIENTS AND METHODS: 40 ET patients without overt vascular disease, and 42 apparently healthy, age and sex-matched control subjects with comparable classical risk factors for atherosclerosis and Framingham risk of coronary disease were enrolled...
June 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/28721151/moderate-dose-atorvastatin-improves-arterial-endothelial-function-in-patients-with-angina-pectoris-and-normal-coronary-angiogram-a-pilot-study
#5
Amela Kabaklić, Zlatko Fras
INTRODUCTION: Endothelial dysfunction could contribute to the pathophysiology of angina pectoris (AP) in patients with normal coronary angiograms. Besides lipid-lowering effects, statins exert pleiotropic effects including improving endothelial function. MATERIAL AND METHODS: Our double-blind study included 58 patients with AP, noninvasively confirmed myocardial ischemia and a normal coronary angiogram. The effect of once-daily 20 mg atorvastatin (A) was compared with placebo (P) for 6 months...
June 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28668398/differences-in-endothelial-dysfunction-induced-by-paroxysmal-and-persistent-atrial-fibrillation-insights-from-restoration-of-sinus-rhythm-by-catheter-ablation
#6
Keisuke Okawa, Toru Miyoshi, Saori Tsukuda, Syouhei Hara, Naoaki Matsuo, Noriyuki Nishibe, Masahiro Sogo, Tomoaki Okada, Kazumasa Nosaka, Kousuke Sakane, Masayuki Doi, Hiroshi Morita, Hiroshi Ito
BACKGROUND: Atrial fibrillation (AF) is associated with endothelial dysfunction. Studies have shown the incidence of cardiovascular events to be greater in patients with persistent AF (PeAF) than paroxysmal AF (PAF). OBJECTIVE: The aim of this study was to investigate whether endothelial dysfunction and the impact of catheter ablation on the endothelial function differs between PAF and PeAF. METHODS: We prospectively measured the endothelial function by reactive hyperemia peripheral arterial tonometry (RH-PAT) in 103 PAF, 75 PeAF, and 51 control patients at baseline, with follow-up in the AF patients at 6 and 12months after the catheter ablation...
June 19, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28628045/cardio-respiratory-effects-of-air-pollution-in-a-panel-study-of-outdoor-physical-activity-and-health-in-rural-older-adults
#7
David M Stieb, Robin Shutt, Lisa Kauri, Sarah Mason, Li Chen, Mieczyslaw Szyszkowicz, Nina A Dobbin, Marc Rigden, Branka Jovic, Marie Mulholland, Martin S Green, Ling Liu, Guillaume Pelletier, Scott A Weichenthal, Robert E Dales, Isaac Luginaah
OBJECTIVE: To examine cardio-respiratory effects of air pollution in rural older adults exercising outdoors. METHODS: Adults 55 and over completed measurements of blood pressure, peak expiratory flow and oximetry daily, and of heart rate variability, endothelial function, spirometry, fraction of exhaled nitric oxide and urinary oxidative stress markers weekly, before and after outdoor exercise, for 10 weeks. Data were analyzed using linear mixed effect models. RESULTS: Pooled estimates combining 2013 (n = 36 participants) and 2014 (n = 41) indicated that an interquartile increase in the air quality health index (AQHI) was associated with a significant (P < 0...
April 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28625369/rationale-and-design-of-the-hunting-for-the-off-target-properties-of-ticagrelor-on-endothelial-function-and-other-circulating-biomarkers-in-humans-hi-tech-trial
#8
RANDOMIZED CONTROLLED TRIAL
Sara Ariotti, Maarten van Leeuwen, Salvatore Brugaletta, Sergio Leonardi, Kristiaan Martijn Akkerhuis, Emrush Rexhaj, Gladys Janssens, Luis Ortega-Paz, Diego Rizzotti, Jan C van den Berge, Dierik Heg, Gloria Francolini, Stephan Windecker, Marco Valgimigli
BACKGROUND: Among the 3 approved oral P2Y12 inhibitors for the treatment for patients with acute coronary syndrome (ACS), ticagrelor, but not prasugrel or clopidogrel, has been associated with off-target properties, such as improved endothelial-dependent vasomotion and increased adenosine plasma levels. METHODS: The HI-TECH study (NCT02587260) is a multinational, randomized, open-label, crossover study with a Latin squares design, conducted at 5 European sites, in which patients free from recurrent ischemic or bleeding events ≥30 days after a qualifying ACS were allocated to sequentially receive a 30 ± 5-day treatment with prasugrel, clopidogrel, and ticagrelor in random order...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28607132/impaired-muscle-oxygenation-and-elevated-exercise-blood-pressure-in-hypertensive-patients-links-with-vascular-stiffness
#9
Konstantina Dipla, Areti Triantafyllou, Nikolaos Koletsos, Stavros Papadopoulos, Vasileios Sachpekidis, Ioannis S Vrabas, Eugenia Gkaliagkousi, Andreas Zafeiridis, Stella Douma
This study examined in vivo (1) skeletal muscle oxygenation and microvascular function, at rest and during handgrip exercise, and (2) their association with macrovascular function and exercise blood pressure (BP), in newly diagnosed, never-treated patients with hypertension and normotensive individuals. Ninety-one individuals (51 hypertensives and 40 normotensives) underwent office and 24-hour ambulatory BP, arterial stiffness, and central aortic BP assessment, followed by a 5-minute arterial occlusion and a 3-minute submaximal handgrip exercise...
June 12, 2017: Hypertension
https://www.readbyqxmd.com/read/28571621/hemodynamic-catecholamine-vasomotor-and-vascular-responses-determinants-of-myocardial-ischemia-during-mental-stress
#10
Muhammad Hammadah, Ayman Alkhoder, Ibhar Al Mheid, Kobina Wilmot, Nino Isakadze, Naser Abdulhadi, Danielle Chou, Malik Obideen, Wesley T O'Neal, Samaah Sullivan, Ayman Samman Tahhan, Heval Mohamed Kelli, Ronnie Ramadan, Pratik Pimple, Pratik Sandesara, Amit J Shah, Laura Ward, Yi-An Ko, Yan Sun, Irina Uphoff, Brad Pearce, Ernest V Garcia, Michael Kutner, J Douglas Bremner, Fabio Esteves, David S Sheps, Paolo Raggi, Viola Vaccarino, Arshed A Quyyumi
AIMS: Mental stress-induced myocardial ischemia (MSIMI) in patients with coronary artery disease (CAD) is associated with adverse cardiovascular outcomes. We aim to assess hemodynamic, neuro-hormonal, endothelial, vasomotor and vascular predictors of MSIMI. METHODS AND RESULTS: We subjected 660 patients with stable CAD to 99mTc sestamibi myocardial perfusion imaging at rest, with mental (speech task) and with conventional (exercise/pharmacological) stress. Endothelium-dependent flow-mediated dilation (FMD), microvascular reactivity [reactive hyperemia index (RHI)] and arterial stiffness [pulse wave velocity (PWV)] were measured at rest and 30-min after mental stress...
September 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28561781/comparison-of-the-peripheral-reactive-hyperemia-index-with-myocardial-perfusion-reserve-by-82-rb-pet-ct-in-hiv-infected-patients
#11
Mathilde Ørbæk, Philip Hasbak, Rasmus Sejersten Ripa, Andreas Kjær, Anne-Mette Lebech, Andreas Knudsen
After the introduction of antiretroviral therapy (ART) the life expectancy of patients infected with human immunodeficiency virus (HIV) is now approaching that of the general population and the importance of non-AIDS co-morbidities is increasing. Specifically, the risk of coronary artery disease (CAD) seems to be higher in HIV-infected patients and an accurate risk prediction of CAD is of high importance for optimal long term treatment. In this study, we assessed the correlation of the endoPAT, which is an office-based CVD screening tool with the myocardial perfusion reserve by (82)-rubidium PET/CT...
May 31, 2017: Diagnostics
https://www.readbyqxmd.com/read/28560282/clinical-and-biochemical-data-of-endothelial-function-in-women-consuming-combined-contraceptives
#12
Irina I Lobysheva, Sandrine van Eeckhoudt, Flavia Dei Zotti, Ahmad Rifahi, Lucie Pothen, Christophe Beauloye, Jean-Luc Balligand
The data presented in this article are associated with the research article entitled "Heme-Nitrosylated Hemoglobin and Oxidative Stress in Women Consuming Combined Contraceptives. Clinical Application of the EPR Spectroscopy" (Lobysheva et al., 2017 [1]), and describe the characteristics of redox status in blood, as well as biochemical and clinical parameters of young female subjects consuming (or not) contraceptive pills (CP). Erythrocyte concentration of reduced thiols reflecting erythrocyte redox capacity was measured before and after sample deproteinization by electron paramagnetic resonance spectroscopy (EPR) using a nitroxide biradical spin probe specifically interacting with reduced thiols; additional data were obtained by a colorimetric method using Ellman׳s reagents in the same samples...
August 2017: Data in Brief
https://www.readbyqxmd.com/read/28553846/the-effects-of-cd4-nadirs-on-vessel-stiffness-in-hiv-patients-undergoing-antiretroviral-therapy
#13
Tomasz Mikuła, Paweł Balsam, Michał Peller, Magdalena Suchacz, Bartosz Puchalski, Łukasz Kołtowski, Kacper Maciejewski, Alicja Wiercińska-Drapało, Grzegorz Opolski, Krzysztof J Filipiak
BACKGROUND: Many factors are associated with HIV (the human immunodeficiency virus) patients having a greater risk of cardiovascular diseases. HIV damages vessel endothelium through chronic inflammation which combined with dyslipidemia, arterial hypertension and antiretroviral therapy leads to the progression of atherosclerotic changes. AIM: Our goal was to determine if a CD4 nadir along with immunologic, inflammatory, biochemical and metabolic markers can be associated with higher vessel stiffness and therefore an increased risk of cardiovascular diseases in patients undergoing antiretroviral therapy for HIV...
May 29, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28526381/medium-term-effect-of-sublingual-l-glutathione-supplementation-on-flow-mediated-dilation-in-subjects-with-cardiovascular-risk-factors
#14
Jonica Campolo, Stefano Bernardi, Lorena Cozzi, Silvia Rocchiccioli, Cinzia Dellanoce, Antonella Cecchettini, Annamaria Tonini, Marina Parolini, Benedetta De Chiara, Gianpaolo Micheloni, Gualtiero Pelosi, Claudio Passino, Cristina Giannattasio, Oberdan Parodi
OBJECTIVE: Supplementation of glutathione (GSH) may be a positive strategy to improve the endogenous antioxidant defense required to counteract many acute and chronic diseases. However, the efficacy of GSH treatment seems to be closely related to type of administration, degree of absorption, and increase of its concentrations. The aim of this study was to test a new sublingual formulation of L-GSH, which enters directly the systemic circulation, to assess its efficacy on circulating biochemical markers of hepatic metabolism, lipid profile, and oxidative stress and on peripheral vascular function compared with placebo in patients with cardiovascular risk factors (CVRF)...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28525354/the-relationship-between-insulin-resistance-and-endothelial-dysfunction-in-obese-adolescents
#15
Preneet Cheema Brar, Payal Patel, Stuart Katz
BACKGROUND: Insulin resistance and endothelial dysfunction share a reciprocal relationship that links the metabolic and cardiovascular sequelae of obesity. We characterized the brachial artery reactivity testing (BART) and carotid artery-intima media thickness (CIMT) in adolescents categorized as obese insulin resistant (OIR) and obese not insulin resistant (ONIR). Lipoprotein particle (p) analysis and inflammatory cytokines in OIR and ONIR groups were also analyzed. METHODS: Obese adolescents (n=40; mean body mass index [BMI] 35...
May 24, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28515707/validation-of-repeated-endothelial-function-measurements-using-endopat-in-stroke
#16
Aina S Hansen, Jawad H Butt, Sonja Holm-Yildiz, William Karlsson, Christina Kruuse
BACKGROUND: Decreased endothelial function (EF) may be a prognostic marker for stroke. Measuring pharmacological effects on EF may be of interest in the development of personalized medicine for stroke prevention. In this study, we assessed the reliability of repeated EF measurements using a pulse amplitude tonometry technology in acute stroke patients. Similarly, reliability was tested in healthy subjects devoid of vascular disease to estimate reactivity and reliability in a younger non-stroke population...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28512721/mid-term-risk-for-subclinical-atherosclerosis-and-chronic-myocarditis-in-children-with-kawasaki-disease-and-transient-coronary-abnormalities
#17
Mansingh Parihar, Surjit Singh, Pandiarajan Vignesh, Anju Gupta, Manojkumar Rohit
There is evidence for premature atherosclerosis and systemic arterial stiffening during follow-up of children with Kawasaki disease (KD) and coronary artery abnormalities (CAA). Moreover, patients with KD may also have subclinical myocardial involvement and inhomogeneous ventricular repolarization. The inhomogeneous ventricular repolarization manifests as increased QT dispersion on electrocardiography. There is a paucity of studies in endothelial dysfunction and QT dispersion in children with KD and transient CAA...
August 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28508133/children-and-adolescents-macrovascular-reactivity-level-and-dynamics-but-not-the-microvascular-response-is-associated-with-body-mass-index-and-arterial-stiffness-levels
#18
Yanina Zócalo, Marco Marotta, Victoria García-Espinosa, Santiago Curcio, Pedro Chiesa, Gustavo Giachetto, Daniel Bia
INTRODUCTION: The existing evidence indicates that primary prevention of atherosclerotic disease should begin in childhood. Detection of children and adolescents at risk for atherosclerosis may allow early intervention to decrease the atherosclerotic process, thereby preventing or delaying cardiovascular disease. Vascular reactivity (VR) is altered even by early atherosclerosis. Obesity is a main cardiovascular risk factor (CVRF) observed in childhood. If childhood obesity associates impaired macro and/or micro VR is controversial...
May 15, 2017: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://www.readbyqxmd.com/read/28488836/effects-of-low-load-resistance-exercise-with-blood-flow-restriction-on-intramuscular-hemodynamics-oxygenation-level-and-water-content
#19
Osamu Yanagisawa, Atsuki Fukutani
BACKGROUND: Muscle metabolism during and after low-load blood flow restriction (BFR) exercise should be further investigated to clarify the mechanism by which the exercise leads to muscle hypertrophy, and increases strength and endurance. We aimed to investigate the effects of low-load resistance exercise with BFR on intramuscular hemodynamics, oxygenation level, and water content. METHODS: Seven men performed ankle plantar flexion exercise (120 repetitions, 30% one repetition maximum) using a custom-made device with and without BFR inside a magnetic resonance scanner...
May 9, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28465609/childhood-body-mass-index-and-endothelial-dysfunction-evaluated-by-peripheral-arterial-tonometry-in-early-midlife
#20
M J A Williams, B J Milne, A Ambler, R Theodore, S Ramrakha, A Caspi, T E Moffitt, R Poulton
BACKGROUND/OBJECTIVES: Endothelial dysfunction predicts mortality but it is unknown whether childhood obesity predicts adult endothelial dysfunction. The aim of this study was to determine whether anthropometric indices of body fat in childhood, adolescence and early midlife are associated with endothelial dysfunction in early midlife. SUBJECTS/METHODS: Participants belonged to a representative birth cohort of 1037 individuals born in Dunedin, New Zealand in 1972 and 1973 and followed to age 38 years, with 95% retention (the Dunedin Multidisciplinary Health and Development Study)...
May 3, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
keyword
keyword
114383
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"