Madoka Mori-Yoshimura, Kazutaka Aizawa, Yoko Shigemoto, Naoko Ishihara, Narihiro Minami, Ichizo Nishino, Sumiko Yoshida, Noriko Sato, Yuji Takahashi
This study aimed to clarify the characteristics and progressive changes of brain image abnormalities in Duchenne muscular dystrophy (DMD). Brain images of 39 adult patients (median age, 24 years) were retrospectively reviewed, along with intellectual and/or neurodevelopmental test results. On magnetic resonance imaging (n = 13), atrophy of the frontal lobe, pars opercularis (without other frontal atrophy), and cerebellum was observed in 6, 1, and 1 patients, respectively. On computed tomography (n = 32), atrophy of the frontal lobe, pars opercularis, temporal lobe, and occipital lobe was observed in 20, 1, 1, and 1 patients, respectively...
February 21, 2022: Neuromuscular Disorders: NMD