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https://www.readbyqxmd.com/read/28109195/fungal-periprosthetic-joint-infection-following-total-elbow-arthroplasty-a-case-report-and-review-of-the-literature
#1
Cory A Kwong, Shannon K T Puloski, Kevin A Hildebrand
BACKGROUND: With improving surgical techniques for total elbow arthroplasty clinical outcomes have improved and its utilization continues to increase. Despite these advances, complication rates remain as high as 24%. Of these complications periprosthetic joint infection is one of the most common and morbid. The rheumatoid elbow remains a leading indication for total elbow arthroplasty. Patients with this condition frequently require immunosuppressive therapy, which places them at higher risk of both typical and atypical infections...
January 21, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28108925/soil-compaction-effects-on-soil-health-and-cropproductivity-an-overview
#2
Adnan Noor Shah, Mohsin Tanveer, Babar Shahzad, Guozheng Yang, Shah Fahad, Saif Ali, Muhammad Adnan Bukhari, Shahbaz Atta Tung, Abdul Hafeez, Biangkham Souliyanonh
Soil compaction causes substantial reduction in agriculture productivity and has always been of great distress for farmers. Intensive agriculture seems to be more crucial in causing compaction. High mechanical load, less crop diversification, intensive grazing, and irrigation methods lead to soil compaction. It is further exasperated when these factors are accompanied with low organic matter, animal trampling, engine vibrations, and tillage at high moisture contents. Soil compaction increases soil bulk density and soil strength, while decreases porosity, aggregate stability index, soil hydraulic conductivity, and nutrient availability, thus reduces soil health...
January 21, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28108860/early-cardioversion-in-atrial-fibrillation-earlier-is-better-but-not-always-and-maybe-not-immediately
#3
REVIEW
Paloma G Piña, Alexandru B Chicos
Atrial fibrillation (AF) is the most common cardiac arrhythmia in humans. One of its important features is the tendency to become more persistent over time, even in the absence of underlying progressive heart disease. Conversion and maintenance of sinus rhythm by pharmacological or electrical methods become increasingly difficult the longer the arrhythmia persists. Electrical, mechanical, structural, and autonomic remodeling processes have been implicated in the mechanisms of AF initiation, perpetuation, and progression...
January 2017: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/28108859/the-arc-gene-confers-genetic-susceptibility-to-alzheimer-s-disease-in-han-chinese
#4
Rui Bi, Li-Li Kong, Min Xu, Guo-Dong Li, Deng-Feng Zhang, Tao Li, Yiru Fang, Chen Zhang, Buchang Zhang, Yong-Gang Yao
Alzheimer's disease (AD) is the most common form of dementia. The deposition of β-amyloid (Aβ) plaques in the brain was considered one of the main neuropathological hallmarks of AD. As the loss of synapses always occurs during AD progression, AD has been gradually regarded as a "synaptopathy." The activity-regulated cytoskeleton-associated protein (Arc) was recently identified as a key factor for AD due to its active roles in synaptic plasticity, learning, memory, and Aβ generation. However, there is little evidence to support the association of the Arc gene with AD...
January 20, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28108751/-compatibility-and-allergies-of-osteosynthesis-materials
#5
M Thomsen, P Thomas
Metal implants for osteosynthesis are nowadays standard in orthopedic and trauma surgery. Steel implants, especially cerclages, bands and wires, can show more corrosion due to friction and lead to encapsulation in connective tissue with fluid borders even without loosening. Corrosion and fluid borders are potentially more susceptible to incompatibility and infections. Titanium implants have the advantage of better allergic compatibility. Problems may occur in material removal, especially with titanium implants because material fractures occur more frequently...
January 20, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28108671/tenacious-d-symbiodinium-in-clade-d-remain-in-reef-corals-at-both-high-and-low-temperature-extremes-despite-impairment
#6
Rachel N Silverstein, Ross Cunning, Andrew C Baker
Reef corals are sensitive to thermal stress, which induces coral bleaching (the loss of algal symbionts), often leading to coral mortality. However, corals hosting certain symbionts (notably Symbiodinium in clade D) resist bleaching when exposed to high temperatures. To determine if these symbionts are also cold tolerant, we exposed corals hosting either Symbiodinium C3 or D1a to incremental warming (+1°C week(-1) to 35°C) and cooling (-1°C week(-1) to 15°C), and measured photodamage and symbiont loss. During warming to 33°C, C3-corals were photodamaged and lost >99% of symbionts, while D1a-corals experienced photodamage but did not bleach...
January 20, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28108441/child-with-multiple-fractures-a-rare-presentation-of-a-common-disease
#7
Filipa Dias Costa, Carla Maia, Susana Almeida, Ricardo Ferreira
Bone fractures are not uncommon in paediatric age. However, when recurrent, an underlying clinical condition must not be excluded. We describe the case of a boy aged 7 years, referred for investigation of recurrent bone fractures. Personal and family histories were unremarkable. Physical examination was normal. Almost all primary bone disorders were excluded. Additional laboratory investigations ruled out the majority of secondary causes of bone fragility. Coeliac disease (CD) serologies, however, were positive, and duodenal biopsies confirmed this diagnosis (Marsh III B)...
January 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28108418/intragenus-campylomormyrus-and-intergenus-hybrids-in-mormyrid-fish-physiological-and-histological-investigations-of-the-electric-organ-ontogeny
#8
Frank Kirschbaum, Linh Nguyen, Stephanie Baumgartner, Linda Chi, Rene Wolfart, Khouloud Elarbani, Hari Eppenstein, Yevheniia Korniienko, Lilian Guido-Böhm, Victor Mamonekene, Marianne Vater, Ralph Tiedemann
African weakly electric mormyrid fish show a high diversity of their electric organ discharge (EOD) both across and within genera. Thanks to a recently developed technique of artificial reproduction in mormyrid fish, we were able to perform hybridizations between different genera and within one genus (Campylomormyrus). The hybrids of intergenus hybridizations exhibited different degrees of reduced survival related to the phylogenetic distance of the parent species: hybrids of the crosses between C. rhynchophorus and its sister genus Gnathonemus survived and developed normally...
January 17, 2017: Journal of Physiology, Paris
https://www.readbyqxmd.com/read/28108303/braf-v600e-mutation-is-not-always-present-as-expected-a-case-report-of-lung-and-thyroid-carcinomas
#9
Nicolas Piton, Mathieu Salaün, Florian Guisier, Florent Marguet, Emmanuel K Touré, Pierre Gémival, Luc Thiberville, Jean-Christophe Sabourin
No abstract text is available yet for this article.
January 17, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28108144/postmortem-in-vitro-ethanol-production-it-could-be-more-common-than-we-think
#10
Maria José Quintas, Pedro Costa, Paula Melo, André Castro, João Miguel Franco, Helena M Teixeira
The blood alcohol concentration (BAC) is the most frequent determination in a Forensic Toxicology Laboratory. Despite its apparent simplicity, the results interpretation can be complex and always have relevant social and legal implications, particularly in postmortem analysis. In the present report we describe the case of a 55-year-old male with an apparent natural death by myocardial infarction, whose initial BAC was 0.18g/L but, in repeated determinations prompted by discrepancies observed in the first two, it rapidly increased to 0...
January 5, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28107900/quality-of-sleep-in-renal-transplant-recipients-and-patients-on-hemodialysis
#11
Paraskevi G Liaveri, Dimitris Dikeos, Ioannis Ilias, Eirini P Lygkoni, Ioannis N Boletis, Chryssanthi Skalioti, Thomas Paparrigopoulos
BACKGROUND: Sleep disorders are very common in patients with chronic kidney disease and they may not always subside after kidney transplantation. AIM AND METHODS: The aim of this cross-sectional study was to evaluate the self-reported quality of sleep, insomnia problems in particular, and examine the factors that disturb sleep of kidney transplant recipients (KTx: n=152) in comparison to age- and sex-matched patients on dialysis (HD: n=67) and participants with normal renal function (NOR: n=49), through the administration of the Athens Insomnia Scale (AIS) at least six months after transplantation...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28107762/thulium-laser-in-interventional-endoscopy-animal-and-human-studies
#12
Gian E Tontini, Helmut Neumann, Luca Pastorelli, Luisa Spina, Flaminia Cavallaro, Paola Soriani, Alessandro Rimondi, Barbara Bruni, Claudio Clemente, Filippo Fagnani, Pavlos Lagoussis, Luca Carmignani, Maurizio Vecchi
Background and study aims The thulium laser system (TLS) is an emerging surgical tool. The 2-μm wavelength provides a confined coagulation depth (0.2 - 0.4 mm) to reduce the potential for inadvertent injuries. For the first time ever, we assessed TLS feasibility for endoscopic hemostasis ex vivo in pigs. In addition, we performed the first in vivo hemostatic treatments in humans. Patients and methods Tissue damage induced by TLS using different settings and optical fibers was compared to that from argon plasma coagulation (APC) in established ex vivo animal models...
January 20, 2017: Endoscopy
https://www.readbyqxmd.com/read/28107437/hyperventilation-with-maintenance-of-isocapnia-an-old-new-method-in-carbon-monoxide-intoxication
#13
Jacek Sein Anand, Daria Schetz, Wojciech Waldman, Marek Wiśniewski
INTRODUCTION: Exposure to carbon monoxide (CO) is among the most common causes of acute and chronic poisonings worldwide. The crucial point of treatment of such acute poisonings is to eliminate CO from the body as fast as possible. There are currently two approaches to the management of the CO intoxication: hyperbaric oxygen therapy (HOT) and normobaric oxygen therapy (NOT). HOT is highly effective and capable of achieving the CO elimination half-time (T½) as low as 15 minutes. Unfortunately this method is expensive and not always readily available...
2017: PloS One
https://www.readbyqxmd.com/read/28107436/a-micro-ct-study-in-patients-with-breast-microcalcifications-using-a-mathematical-algorithm-to-assess-3d-structure
#14
David Kenkel, Zsuzsanna Varga, Heike Heuer, Konstantin J Dedes, Nicole Berger, Lukas Filli, Andreas Boss
PURPOSE: The aim of this study was to evaluate the relevance of the three-dimensional (3D) structure of breast microcalcifications (MC) as a predictor of malignancy using highly resolved micro-computed tomography (micro-CT) datasets of biopsy samples. MATERIAL AND METHODS: The study included 28 women with suspicious MC in their mammogram undergoing vacuum-assisted biopsy. Directly after the intervention, the specimens were scanned in a micro-CT with an isometric spatial resolution of 9 μm...
2017: PloS One
https://www.readbyqxmd.com/read/28107432/ongoing-speciation-and-gene-flow-between-taxonomically-challenging-trochulus-species-complex-gastropoda-hygromiidae
#15
Małgorzata Proćków, Tomasz Strzała, Elżbieta Kuźnik-Kowalska, Jarosław Proćków, Paweł Mackiewicz
Geographical isolation, selection and genetic drift can cause the geographical diversification of populations and lead to speciation. Land snail species in the genus Trochulus show overlaps in geographical ranges as well as in morphology, but genetic data do not always support the species-level taxonomy based on morphological characters. Such a group offers an excellent opportunity to explore the processes involved. We have addressed the problem by determining the status of the restricted endemic T. graminicola within the larger context of Trochulus taxonomy...
2017: PloS One
https://www.readbyqxmd.com/read/28107040/effects-of-malnutrition-on-neutrophil-mononuclear-cell-apoptotic-functions-in-children-with-acute-lymphoblastic-leukemia
#16
Fatma Betul Cakir, Su Gülsün Berrak, Gonul Aydogan, Aysin Tulunay, Cetin Timur, Cengiz Canpolat, Emel Eksioglu Demiralp
BACKGROUND: Recent studies claim that apoptosis may explain immune dysfunction observed in malnutrition. OBJECTIVE: The objective of this study was to determine the effect of malnutrition on apoptotic functions of phagocytic cells in acute lymphoblastic leukemia (ALL). MATERIALS AND METHODS: Twenty-eight ALL patients (13 with malnutrition) and thirty controls were enrolled. Neutrophil and mononuclear cell apoptosis of ALL patients and the control group were studied on admission before chemotherapy and repeated at a minimum of three months after induction of chemotherapy or when the nutritional status of leukemic children improved...
January 20, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28106905/non-inferiority-trials-no-better-no-worse-no-change-no-pain
#17
REVIEW
Robert K Hills
With improvements in care over time it becomes harder to improve clinical outcomes in those conditions where cure rates are high. The focus of research can thus turn to the so-called non-inferiority trial: where the main aim is not to improve clinical outcome, but instead to provide evidence of a lack of difference, whilst other issues, such as cost or toxicity, are improved. The interpretation of such trials is not always straightforward. The burden of proof is reversed compared to a traditional superiority trial, and this means that many of the statistical safeguards, such as significance and intention-to-treat, which act as restraints from an overhasty adoption of a new therapy, may actually work in the opposite fashion...
January 20, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28106712/very-low-protein-diet-vlpd-reduces-metabolic-acidosis-in-subjects-with-chronic-kidney-disease-the-nutritional-light-signal-of-the-renal-acid-load
#18
Biagio Raffaele Di Iorio, Lucia Di Micco, Stefania Marzocco, Emanuele De Simone, Antonietta De Blasio, Maria Luisa Sirico, Luca Nardone, On Behalf Of Ubi Study Group
BACKGROUND: Metabolic acidosis is a common complication of chronic kidney disease; current guidelines recommend treatment with alkali if bicarbonate levels are lower than 22 mMol/L. In fact, recent studies have shown that an early administration of alkali reduces progression of CKD. The aim of the study is to evaluate the effect of fruit and vegetables to reduce the acid load in CKD. METHODS: We conducted a case-control study in 146 patients who received sodium bicarbonate...
January 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28106538/a-polymorphism-in-mir-34b-c-as-a-potential-biomarker-for-early-onset-of-hereditary-retinoblastoma
#19
Ivna N S R Carvalho, Adriana H O Reis, Anna C E Dos Santos, Fernando R Vargas
BACKGROUND: Retinoblastoma (RB) is a malignant pediatric tumor and, mainly because of late diagnosis, most patients undergo enucleation. The tumor almost always initiates by two inactivation events at the RB1 gene. Single nucleotide polymorphisms (SNPs) in p53 pathway have been found to represent genetic modifiers of RB. OBJECTIVE: To investigate whether a SNP (rs4938723T > C) in mir-34b/c gene, a key effector of p53, could influence RB risk and patients' age of onset...
January 13, 2017: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/28106450/nontrivial-role-of-interlayer-cation-states-in-iron-based-superconductors
#20
Daniel Guterding, Harald O Jeschke, I I Mazin, J K Glasbrenner, E Bascones, Roser Valentí
Unconventional superconductivity in iron pnictides and chalcogenides has been suggested to be controlled by the interplay of low-energy antiferromagnetic spin fluctuations and the particular topology of the Fermi surface in these materials. Based on this premise, one would also expect the large class of isostructural and isoelectronic iron germanide compounds to be good superconductors. As a matter of fact, they, however, superconduct at very low temperatures or not at all. In this work we establish that superconductivity in iron germanides is suppressed by strong ferromagnetic tendencies, which surprisingly do not originate from changes in bond angles or bond distances with respect to iron pnictides and chalcogenides, but are due to changes in the electronic structure in a wide range of energies happening upon substitution of atom species (As by Ge and the corresponding spacer cations)...
January 6, 2017: Physical Review Letters
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