keyword
MENU ▼
Read by QxMD icon Read
search

Toxic alcohol

keyword
https://www.readbyqxmd.com/read/28546081/targeting-nuclear-receptors-for-the-treatment-of-fatty-liver-disease
#1
REVIEW
Naoki Tanaka, Toshifumi Aoyama, Shioko Kimura, Frank J Gonzalez
Ligand-activated nuclear receptors, including peroxisome proliferator-activated receptor alpha (PPARα), pregnane X receptor, and constitutive androstane receptor, were first identified as key regulators of the responses against chemical toxicants. However, numerous studies using mouse disease models and human samples have revealed critical roles for these receptors and others, such as PPARβ/δ, PPARγ, farn esoid X receptor (FXR), and liver X receptor (LXR), in maintaining nutrient/energy homeostasis in part through modulation of the gut-liver-adipose axis...
May 22, 2017: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28540764/japan-flavour-and-fragrance-materials-association-s-safety-assessment-of-food-flavouring-substances-uniquely-used-in-japan-that-belong-to-the-class-of-aliphatic-primary-alcohols-aldehydes-carboxylic-acids-acetals-and-esters-containing-additional-oxygenated
#2
Kenji Saito, Yasuko Hasegawa-Baba, Fumiko Sekiya, Shim-Mo Hayashi, Yoshiharu Mirokuji, Hiroyuki Okamura, Shinpei Maruyama, Atsushi Ono, Madoka Nakajima, Masakuni Degawa, Shogo Ozawa, Makoto Shibutani, Tamio Maitani
We performed a safety evaluation using the procedure devised by the Joint FAO/WHO Expert Committee on Food Additives of the following four flavouring substances that belong to the class of 'aliphatic primary alcohols, aldehydes, carboxylic acids, acetals, and esters containing additional oxygenated functional groups' and are uniquely used in Japan: butyl butyrylacetate, ethyl 2-hydroxy-4-methylpentanoate, 3-hydroxyhexanoic acid and methyl hydroxyacetate. Although no genotoxicity study data were found in the published literature, none of the four substances had chemical structural alerts predicting genotoxicity...
May 25, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28539265/removal-of-toxic-heavy-metal-lead-ii-using-chitosan-oligosaccharide-graft-maleic-anhydride-polyvinyl-alcohol-silk-fibroin-composite
#3
Ajitha P, Vijayalakshmi K, Saranya M, Gomathi T, Rani K, Sudha P N, Anil Sukumaran
The present work was aimed to investigate the efficiency of novel chitosan oligosaccharide-graft-maleic anhydride(COS-g-MAH)/Polyvinyl alcohol (PVA)/silk fibroin (SF) composite for removing the toxic heavy metal lead (II) ion from aqueous solution by batch adsorption studies. Initially the chitosan oligosaccharide-graft-maleic anhydride copolymer has been prepared by utilizing ceric ammonium nitrate as an initiator and the optimised graft copolymer was then used for synthesizing COS-g-MAH/PVA/SF composite. The prepared samples were analyzed through FTIR and XRD studies...
May 21, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28533839/-epidemiology-of-the-relationship-between-atrial-fibrillation-and-heart-failure
#4
Yassine Ragbaoui, Chafia Chehbouni, Ayoub El Hammiri, Rachida Habbal
Atrial fibrillation and heart failure are diseases which often coexist aggravating prognosis and constituting a major public health problem. The aim of this study was to assess the prevalence of atrial fibrillation in patients with chronic heart failure and to determine the clinical profile of this group of patients. We conducted a retrospective descriptive study based on the registry of heart failure of the Department of Cardiology at the University Hospital Centre from June 2006 to March 2015. All patients over 18 years of age with chronic heart failure associated with atrial fibrillation were included in the study...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28531658/co-plantation-of-aquatic-macrophytes-typha-angustifolia-and-paspalum-scrobiculatum-for-effective-treatment-of-textile-industry-effluent
#5
Vishal V Chandanshive, Niraj R Rane, Asif S Tamboli, Avinash R Gholave, Rahul V Khandare, Sanjay P Govindwar
Field treatment of textile industry effluent was carried out in constructed drenches (91.4m×1.2m×0.6m; 65.8m(3)) planted independently with Typha angustifolia, Paspalum scrobiculatum and their co-plantation (consortium-TP). The in situ treatment of effluent by T. angustifolia, P. scrobiculatum and consortium-TP was found to decrease ADMI color value by 62, 59 and 76%, COD by 65, 63 and 70%, BOD by 68, 63 and 75%, TDS by 45, 39 and 57%, and TSS by 35, 31 and 47%, respectively within 96h. Heavy metals such as arsenic, cadmium, chromium and lead were also removed up to 28-77% after phytoremediation...
May 12, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28526123/-direct-mechanism-of-action-in-toxic-myopathies
#6
REVIEW
A Khelfi, M Azzouz, R Abtroun, M Reggabi, B Alamir
Toxic myopathies are a large group of disorders generated by surrounding agents and characterized by structural and/or functional disturbances of muscles. The most recurrent are those induced by commonly used medications. Illicit drugs, environmental toxins from animals, vegetables, or produced by micro-organisms as well as chemical products commonly used are significant causes of such disorders. The muscle toxicity results from multiple mechanisms at different biological levels. Many agents can induce myotoxicity through a direct mechanism in which statins, glucocorticoids and ethyl alcohol are the most representative...
May 16, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28525761/impact-of-bioactive-packaging-systems-based-on-evoh-films-and-essential-oils-in-the-control-of-aflatoxigenic-fungi-and-aflatoxin-production-in-maize
#7
Eva M Mateo, José V Gómez, Irene Domínguez, Jose V Gimeno-Adelantado, Rufino Mateo-Castro, Rafael Gavara, Misericordia Jiménez
Aspergillus flavus and A. parasiticus are the most common fungal species associated with aflatoxin (AF) contamination of cereals, especially maize, and other agricultural commodities. AFB1, the most frequent and toxic metabolite, is a powerful hepatotoxic, teratogenic and mutagenic compound. Effective strategies to control these fungal species and AFs in food and feed are required. Active packaging film containing essential oils (EO) is one of the most innovative food packaging concepts. In this study, ethylene-vinyl alcohol (EVOH) copolymer films incorporating EO from Origanum vulgare (ORE), Cinnamomum zeylanicum (CIN) or their major active constituents, carvacrol (CAR) and cinnamaldehyde (CINHO), respectively, were developed and assayed to control growth of A...
May 11, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28515763/poly-ethylene-co-vinyl-alcohol-based-polymeric-thermo-responsive-nanocarriers-for-controlled-delivery-of-epirubicin-to-hepatocellular-carcinoma
#8
Farshid Hassanzadeh, Maryam Farzan, Jaleh Varshosaz, Ghadam Ali Khodarahmi, Sahar Maaleki, Mahboubeh Rostami
In this study, poly(ethylene-co-vinyl alcohol) (EVOH) as a novel biocompatible polymeric scaffold was surface modified by succinylation to get EVOHS and further pegylated to improve structural properties using methoxypolyethylene glycol (5000 Da) succinate (PEGS) along with targeting with retinoic acid (RA) to get final modified active and passive targeted conjugate (PEGS-EVOHS-RA) to evaluate its ability in carrying and delivery of epirubicin to hepatocellular carcinoma cell lines in response to varying temperatures...
April 2017: Research in Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28513335/tio2-uv-assisted-rhodamine-b-degradation-putative-pathway-and-identification-of-intermediates-by-uplc-ms
#9
Tahir Rasheed, Muhammad Bilal, Hafiz M N Iqbal, Syed Zakir Hussain Shah, Hongbo Hu, Xuehong Zhang, Yongfeng Zhou
The present study was designed to evaluate the photocatalytic degradation of Rhodamine B (Rh-B) in a self-assembled TiO2 assisted system under UV light irradiation. Chemical oxygen demand (COD), total organic carbon (TOC), and high-performance liquid chromatography (HPLC) analyses confirmed the elevated Rh-B degradation level. A stepwise meticulous breakdown pathway based on the ultra-performance liquid chromatography coupled with electrospray ionization mass spectrometry (UPLC-MS) is proposed. Results demonstrated that the degradation of Rh-B mainly occurred via N-de-ethylation process, and N-de-ethylated intermediate products were further oxidized into acids and alcohols...
May 17, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28503896/antibacterial-efficacy-of-poly-vinyl-alcohol-composite-nanofibers-embedded-with-silver-anchored-silica-nanoparticles
#10
Abdul Wahab Jatoi, Yun Kee Jo, Hoik Lee, Seong-Geun Oh, Dong Soo Hwang, Zeeshan Khatri, Hyung Joon Cha, Ick Soo Kim
Silver has been widely used as an effective antibacterial agent especially for treating burns and wounds. However, release of silver from materials often arouse side effects due to toxicity of silver towards mammalian cells. Argyria and argyrosis are well known problems of acute toxicity of silver towards human body. Immobilization of silver is an effective approach to reduce silver release. Herein, we present poly(vinyl alcohol) (PVA) composite nanofibers embedded with silver-anchored silica nanoparticles (SSNs) as a novel antibacterial material...
May 15, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28503197/the-significance-of-proline-and-glutamate-on-butanol-chaotropic-stress-in-bacillus-subtilis-168
#11
Gumpanat Mahipant, Atchara Paemanee, Sittiruk Roytrakul, Junichi Kato, Alisa S Vangnai
BACKGROUND: Butanol is an intensively used industrial solvent and an attractive alternative biofuel, but the bioproduction suffers from its high toxicity. Among the native butanol producers and heterologous butanol-producing hosts, Bacillus subtilis 168 exhibited relatively higher butanol tolerance. Nevertheless, organic solvent tolerance mechanisms in Bacilli and Gram-positive bacteria have relatively less information. Thus, this study aimed to elucidate butanol stress responses that may involve in unique tolerance of B...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28501158/poly-vinyl-alcohol-capped-silver-nanoparticles-for-antioxidant-assay-based-on-seed-mediated-nanoparticle-growth
#12
Saowapak Teerasong, Amornrassamee Jinnarak, Sumonmarn Chaneam, Prapin Wilairat, Duangjai Nacapricha
A simple and rapid method for measurement of total antioxidant capacity (TAC) was developed. In this work, gallic acid was used as the antioxidant standard. Poly(vinyl alcohol) embedded silver nanoparticles (PVA-AgNPs) were employed as a colorimetric sensor. The detection principle was based on the seed-mediated nanoparticle growth technique. The PVA-AgNPs act as a catalyst in the reduction of Ag(+) by gallic acid by providing nucleation seeds. Ag(+) was reduced to Ag° and accumulated on the PVA-AgNP surface, leading to an increase in the size of particles...
August 1, 2017: Talanta
https://www.readbyqxmd.com/read/28495475/ameliorative-effects-of-achillea-millefolium-inflorescences-alcoholic-extract-against-nicotine-induced-reproductive-failure-in-rat
#13
M Hallaj Salahipour, Sh Hasanzadeh, H Malekinejad
BACKGROUND: Nicotine (Nic) is a major risk factor in the development of functional disorders of male reproductive system. Achillea millefolium; is highly regarded for medicinal activities, due to its antioxidant and anti-inflammatory properties. This study was carried out to evaluate whether Achillea millefolium (Achm) inflorescences alcoholic extract could serve as a protective agent in male reproductive male failures during Nic exposure in a rat model. METHODS: Twenty-five adult male Wistar rats were categorized into the five groups...
May 8, 2017: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
https://www.readbyqxmd.com/read/28490991/other-non-surgical-treatments-for-liver-cancer
#14
Paul Revel-Mouroz, Philippe Otal, Marion Jaffro, Antoine Petermann, Olivier Meyrignac, Pierre Rabinel, Fatima-Zohra Mokrane
Interventional radiology plays a major role in the modern management of liver cancers, in primary hepatic malignancies or metastases and in palliative or curative situations. Radiological treatments are divided in two categories based on their approach: endovascular treatment and direct transcapsular access. Endovascular treatments include mainly three applications: transarterial chemoembolization (TACE), transarterial radioembolization (TARE) and portal vein embolization (PVE). TACE and TARE share an endovascular arterial approach, consisting of a selective catheterization of the hepatic artery or its branches...
March 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/28489907/anti-oxidative-effects-of-4-hydroxybenzyl-alcohol-in-astrocytes-confer-protective-effects-in-autocrine-and-paracrine-manners
#15
Lidan Luo, Seung-Woo Kim, Hye-Kyung Lee, Il-Doo Kim, Hahnbie Lee, Ja-Kyeong Lee
4-Hydroxybenzyl alcohol (4-HBA) is an important phenolic constituent of Gastrodia elata Blume (GEB), a traditional herbal medicine used in East Asia. Many activities have been reported to underlie the beneficial effects of 4-HBA in the brain, and in particular, its anti-inflammatory, anti-oxidative, and anti-zinc-toxic effects have been implicated in the postischemic brain. Here, the authors investigated the anti-oxidative effect of 4-HBA on astrocytes and sought to identify the underlying molecular mechanisms involved...
2017: PloS One
https://www.readbyqxmd.com/read/28488428/contribution-of-charges-in-polyvinyl-alcohol-networks-to-marine-antifouling
#16
Wufang Yang, Peng Lin, Daocang Cheng, Longzhou Zhang, Yang Wu, Yupeng Liu, Xiaowei Pei, Feng Zhou
Semi-interpenetrated polyvinyl alcohol polymer networks (SIPNs) were prepared by integrating various charged components into polyvinyl alcohol polymer. Contact angle measurement, attenuated total reflection fourier transform infrared spectroscopy (ART-FTIR), field emission scanning electron microscope (FE-SEM) and tensile tests were used to characterize the physicochemical properties of the prepared SIPNs. In order to investigate the contribution of charges to the marine antifouling, the adhesion behaviors of green alga D...
May 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28485081/risk-of-different-precipitating-events-for-progressing-to-acute-on-chronic-liver-failure-in-hbv-related-cirrhotic-patients
#17
Shan Yin, Shi Jin Wang, Wen Yi Gu, Yan Zhang, Liu Ying Chen, Hai Li
OBJECTIVE: Acute-on-chronic liver failure (ACLF) is a distinct syndrome that develops in cirrhotic patients with acute decompensation (AD). This study focused on the precipitating events (PEs) of HBV related cirrhotic ACLF diagnosed by CLIF-OF score. METHODS: 890 hospitalized HBV related cirrhotic patients with AD were retrospectively included from Renji hospital, Shanghai, China. Precipitating events, CLIF-OF score, and short term prognosis were evaluated. RESULTS: For enrolled 890 patients, there were 300 (33...
May 9, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28482932/do-pre-hospital-poisoning-deaths-differ-from-in-hospital-deaths-a-retrospective-analysis
#18
Lauri Koskela, Lasse Raatiniemi, Håkon Kvåle Bakke, Tero Ala-Kokko, Janne Liisanantti
BACKGROUND: Most fatal poisonings occur outside the hospital and the victims found dead. The purpose of this study was to determine the general pattern and patient demographics of fatal poisonings in Northern Finland. In particular, we wanted to analyze differences between pre-hospital and in-hospital deaths. METHODS: All fatal poisonings that occurred in Northern Finland in 2007-2011 were retrieved from the Cause of Death Registry provided by Statistics Finland...
May 8, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28481237/anti-onchocerca-and-anti-caenorhabditis-activity-of-a-hydro-alcoholic-extract-from-the-fruits-of-acacia-nilotica-and-some-proanthocyanidin-derivatives
#19
Jacqueline Dikti Vildina, Justin Kalmobe, Boursou Djafsia, Thomas J Schmidt, Eva Liebau, Dieudonne Ndjonka
Acacia nilotica fruits with high tannin content are used in the northern parts of Cameroon as anti-filarial remedies by traditional healers. In this study, the hydro-alcoholic fruit extract (crude extract (CE)) and, one of the main constituents in its most active fractions, (+)-catechin-3-O-gallate (CG), as well as four related proanthocyanidins, (-)-epicatechin-3-O-gallate (ECG), (+)-gallocatechin (GC), (-)-epigallocatechin (EGC) and (-)-epigallocatechin-3-O-gallate (EGCG), were assessed for their potential in vitro anthelmintic properties against the free-living model organism Caenorhabditis elegans and against the cattle filarial parasite Onchocerca ochengi...
May 6, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28462386/association-of-variants-of-arginine-vasopressin-and-arginine%C3%A2-vasopressin-receptor-1a-with-severe-acetaminophen%C3%A2-liver-injury
#20
Matthew Randesi, Orna Levran, Joel Correa da Rosa, Julia Hankins, Jody Rule, Mary Jeanne Kreek, William M Lee
BACKGROUND & AIMS: Acetaminophen-related acute liver injury and liver failure (ALF) result from ingestion of supratherapeutic quantities of this analgesic, frequently in association with other forms of substance abuse including alcohol, opioids, and cocaine. Thus, overdosing represents a unique high-risk behavior associated with other forms of drug use disorder. METHODS: We examined a series of 21 single nucleotide polymorphisms (SNPs) in 9 genes related to impulsivity and/or stress responsivity that may modify response to stress...
May 2017: Cellular and Molecular Gastroenterology and Hepatology
keyword
keyword
114344
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"