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Arterial insuficiency

Tadeusz Przewłocki, Anna Kabłak-Ziembicka, Wiesława Tracz, Artur Kozanecki, Grzegorz Kopeć, Paweł Rubiś, Magdalena Kostkiewicz, Agnieszka Rosławiecka, Daniel Rzeźnik, Tomasz Stompór
BACKGROUND: Renal dysfunction is an important factor of cardiovascular risk. Renal artery stenosis (RAS) is a potential cause of secondary hypertension and by renal ischemia may lead to progressive renal insuficiency. In RAS patients a significant increase in prevalence of coronary artery disease (CAD) as well as revascularisation rate and mortality rate was observed. AIM: To determine the prevalence of RAS in patients with suspected CAD. METHODS: The study group consisted of 1036 consecutive patients (700 men; 67...
August 2008: Kardiologia Polska
F L Nobre
Angiotensin II antagonists block the actions of angiotensin II by occupying the AT1 receptors. With this blockade there is no bradykinin increase, the angiotensin II synthetized by the cardiac chymase is also blocked, and the AT2 receptor is stimulated (antiproliferative effect). In animal experiments, losartan reverses left ventricular hypertrophy, inhibits myocardial fibrosis and diabetic glomerulosclerosis and significantly protects from vascular cerebral diseases. In humans, the efficacy of the angiotensin II antagonists and that of other antihypertensives is similar and is potentiated by the addition of a thiazide...
April 1999: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
W B Hood
Physiologic concepts relating to reperfusion of ischemic areas of myocardium may be applied both to acute coronary insuficiency, manifested by angina pectoris, and to restoration of coronary blood flow by coronary bypass procedures, currently employed both in acute myocardial infarction and in chronic myocardial ischemia for relief of angina pectoris. Of the information currently available from experimental studies, much may be applicable to the clinical situation. After acutr transient coronary occlusion mechanical and electrical properties of the ischemic area rapidly return to normal, but there is prolongation of tension development and occurrence of ventricular arrhythmias; implications of these phenomena for clinical coronary ischemia deserve exploration...
1975: Advances in Cardiology
N K Lohiya, V P Dixit
A single subcutaneous injection of cadmium chloride (0.04 m mol/kg body weight) did not cause any change in the macroscopic and microscopic features of testes and caput epididymis of Suncus. Testes and sex accessory glands did not show any significant change in their weights. Seminal vesicular fructose concentration remains unchanged. The tetes and sex accessory organs of gerbil under comparable condition showed significant weight loss and shrinkage in tubule diameter. The seminiferous epithelium was totally destroyed...
March 1976: Acta Europaea Fertilitatis
J M López-Novoa, M A Rengel, F J Ortega, J L Rodicio, L Hernando
The effect of nearly total renal ischemia during a two hour period on glomerular filtration and urine composition was studied in relation to tubular permeability and tubular obstruction, two mechanisms that could explain renal insuficiency after iscehmia. Studies on creatinine clearance, micropuncture and microinjection of 14C-inulin into the proximal tubules by means of a hydraulic system were performed before and after the period of ischemia. Thirty minutes after the withdrawal of arterial obstruction, the animals exhibited a maintained diuresis, 50 per cent reduction in glomerular filtration in the superficial nephrons and in the total kidney, a reduction in the proximal fractional absorption of water, and also an increase in the urinary elimination of sodium...
March 1977: Revista Española de Fisiología
V B Vorob'ev
No abstract text is available yet for this article.
January 1979: Sovetskaia Meditsina
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