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Brain eating amoeba

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https://www.readbyqxmd.com/read/27756136/torn-from-the-headlines-surviving-the-brain-eating-amoeba
#1
Craig W Lindsley
No abstract text is available yet for this article.
October 19, 2016: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/27381464/naegleria-fowleri-after-50-years-is-it-a-neglected-pathogen
#2
Moisés Martínez-Castillo, Roberto Cárdenas-Zúñiga, Daniel Coronado-Velázquez, Anjan Debnath, Jesús Serrano-Luna, Mineko Shibayama
It has been 50 years since the first case of primary amoebic meningoencephalitis (PAM) an acute and rapidly fatal disease of the central nervous system (CNS) was reported in Australia. It is now known that the etiological agent of PAM is Naegleria fowleri, an amoeba that is commonly known as "the brain-eating amoeba". N. fowleri infects humans of different ages which are in contact with contaminated water with this microorganism. N. fowleri is distributed worldwide and is found growing in bodies of freshwater in tropical and subtropical environments...
July 4, 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27297387/nlrp3-inflammasome-activation-in-thp-1-target-cells-triggered-by-pathogenic-naegleria-fowleri
#3
Jong-Hyun Kim, Hae-Jin Sohn, Jong-Kyun Yoo, Heekyoung Kang, Gi-Sang Seong, Yong-Joon Chwae, Kyongmin Kim, Sun Park, Ho-Joon Shin
Naegleria fowleri, known as the brain-eating amoeba, causes acute primary amoebic meningoencephalitis. During swimming and other recreational water activities, N. fowleri trophozoites penetrate the nasal mucosa and invade the olfactory bulbs, resulting in intense inflammatory reactions in the forebrain tissue. To investigate what kinds of inflammasome molecules are expressed in target cells due to N. fowleri infection, human macrophage cells (THP-1 cells) were cocultured with N. fowleri trophozoites in a noncontact system, and consequently, interleukin-1β (IL-1β) production was estimated...
September 2016: Infection and Immunity
https://www.readbyqxmd.com/read/26721056/naeglaria-fowleri-the-brain-eating-amoeba-or-an-enigma
#4
REVIEW
Fatima Mukhtar, Mohammad Salim Wazir
Naeglaria fowleri (N. fowleri), popularly known as the brain eating amoeba is the causative agent of the fulminant disease, primary amoebic meningoencephalitis (PAM). Although a rare disease, it is a threat to human health with a case fatality rate ranging from 95-99%. PAM cases have been reported from the United States of America, Australia, Europe and Asia. From 1962 to 2014, 133 people have been infected by N. fowleri in the USA, out of which only three have survived. None of the PAM cases reported in Pakistan so far has survived...
July 2015: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/26591176/primary-amoebic-meningoencephalitis
#5
Ritu Gupta, M K Parashar, Aditya Kale
Primary amoebic meningoencephalitis due to free living amoeba, also called 'brain eating amoeba', Naegleria fowleri, was detected in retroviral disease patient of 40 years who has history of using well water. Patient was admitted with severe headache, fever intermittent, nausea, vomiting and slurring of speech. CT scan and MRI scan findings were normal. CSF examination showed increased protein, low sugar and predominant lymphocytes. CSF was negative for cryptococcal antigen but wet mount preparation showed highly motile free living amoeba Naegleria fowleri...
April 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/25930186/pathogenesis-of-amoebic-encephalitis-are-the-amoebae-being-credited-to-an-inside-job-done-by-the-host-immune-response
#6
REVIEW
Abdul Mannan Baig
Pathogenic free living amoeba like Naegleria fowleri, Acanthamoeba spp., and Balamuthia mandrillaris are known to cause fatal "amoebic meningoencephalitis" by acquiring different route of entries to the brain. The host immune response to these protist pathogens differs from each another, as evidenced by the postmortem gross and microscopic findings from the brains of the affected patients. Cited with the expression of 'brain eating amoeba' when the infection is caused by N. fowleri, this expression is making its way into parasitology journals and books...
August 2015: Acta Tropica
https://www.readbyqxmd.com/read/25445746/tackling-infection-owing-to-brain-eating-amoeba
#7
REVIEW
Abdul Mannan Baig, Naveed Ahmed Khan
In view of the devastating nature of primary amoebic meningoencephalitis caused by Naegleria fowleri and the problems associated with diagnostic delays and chemotherapeutic failures, here we propose a noninvasive diagnostic method using the 'reverse transcribrial route device', a novel strategy in the management of this life-threatening infection with a case fatality rate of more than 90%. The proposed rationale should stimulate interest in this emerging infection that almost always proves fatal.
February 2015: Acta Tropica
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