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https://www.readbyqxmd.com/read/29054839/incremental-prognostic-utility-of-left-ventricular-global-longitudinal-strain-in-hypertrophic-obstructive-cardiomyopathy-patients-and-preserved-left-ventricular-ejection-fraction
#1
Albree Tower-Rader, Jorge Betancor, Zoran B Popovic, Kimi Sato, Maran Thamilarasan, Nicholas G Smedira, Harry M Lever, Milind Y Desai
BACKGROUND: In obstructive hypertrophic cardiomyopathy patients with preserved left ventricular (LV) ejection fraction, we sought to determine whether LV global longitudinal strain (LV-GLS) provided incremental prognostic utility. METHODS AND RESULTS: We studied 1019 patients with documented hypertrophic cardiomyopathy (mean age, 50±12 years; 63% men) evaluated at our center between 2001 and 2011. We excluded age <18 years, maximal LV outflow tract gradient <30 mm Hg, bundle branch block or atrial fibrillation, past pacemaker/cardiac surgery, including myectomy/alcohol ablation, and obstructive coronary artery disease...
October 20, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29041877/-myocardial-infarction-at-the-background-of-left-bundle-branch-block-in-the-record-3-registry-management-and-prognosis
#2
V D Duplyakov, D A Erlikh, B Z Dzhinibalaeva, R A Kiselev, M O Posnenkova
PURPOSE: To study prognostic value of left bundle brunch block (LBBB) in patients with verified myocardial infarction in real clinical practice. MATERIAL AND METHODS: This analysis has been based on data from the RECORD-3 registry. This registry enrolled consecutive patients hospitalized in participating centers with suspected acute coronary syndrome. Among 2368 included patients 91 (3.84%) had LBBB on admission ECG ("new" in 25 [27.4%], "old" in 28 [30.8%]), and of "undetermined duration" in 38 [41...
July 2017: Kardiologiia
https://www.readbyqxmd.com/read/29040663/heart-type-fatty-acid-binding-protein-h-fabp-and-highly-sensitive-troponin-t-hstnt-as-markers-of-myocardial-injury-and-cardiovascular-events-in-elective-percutaneous-coronary-intervention-pci
#3
M Connolly, J Shand, M Kinnin, I Menown, M J Kurth, J Lamont, D Mc Eneaney
OBJECTIVES: To assess the prognostic value of biomarkers of myocardial injury following elective percutaneous coronary intervention (PCI). BACKGROUND: Type 4a myocardial infarction (MI) occurs when myocardial injury is combined with either symptoms suggestive of myocardial ischaemia, new left bundle branch block, angiographic loss of patency of a major artery or imaging suggestive of new loss of myocardium. Myocardial injury is defined as a rise of > 5 x 99th upper reference limit (URL) of 14ng/L (i...
October 10, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29039825/-time-course-of-changes-in-left-ventricular-twist-in-the-presence-of-idiopathic-left-bundle-branch-block-during-exercise-testing
#4
E N Pavlyukova, D A Kuzhel, G V Matyushin
AIM: To investigate left ventricular (LV) deformation properties, rotation, and twist during a bicycle ergometer exercise test among patients with idiopathic left bundle branch block (LBBB). SUBJECTS AND METHODS: Thirty-four patients with idiopathic LBBB having a mean QRS duration of 153±24 msec were examined. A control group included 18 apparently healthy volunteers. All the patients and apparently healthy individuals underwent echocardiography to determine LV hemodynamic parameters, deformity, rotation and twist at rest and after exercise test...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29037444/prevalence-and-prognostic-relevance-of-ventricular-conduction-disturbances-in-patients-with-aortic-stenosis
#5
Edgard A Prihadi, Melissa Leung, E Mara Vollema, Arnold C T Ng, Nina Ajmone Marsan, Jeroen J Bax, Victoria Delgado
The prevalence and prognostic implications of ventricular conduction disturbances in aortic stenosis (AS) have not been extensively evaluated. The present retrospective study investigated the prevalence and prognostic implications of ventricular conduction abnormalities (including the QRS morphology and duration) in AS. A total of 1,245 patients (mean age 66 ± 14 years, 62.8% men) with varying AS severity (aortic sclerosis 33.9%, mild AS 11.5%, moderate AS 29.9%, and severe AS 24.7%) were evaluated. Demographic, clinical variables, and presence of ventricular conduction abnormalities on the electrocardiogram (based on QRS morphology and duration) were related to occurrence of all-cause mortality, correcting for occurrence of aortic valve replacement...
September 18, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29034539/recurrent-extensive-anterior-myocardial-infarction-with-left-and-right-bundle-branch-block
#6
Hexi Jiang, Qinghua Chang, Yingjie Zhang, Renguang Liu
The diagnosis of myocardial infarction with left bundle branch block is difficult. We report a case of 56-year-old man with old extensive anterior myocardial infarction and left bundle branch block (masked each other). The recurrent myocardial infarction indicated right bundle branch block and first-degree atrioventricular block, making a clear diagnosis of complicated and interesting ECG.
October 15, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29032362/simple-six-item-clinical-score-improves-risk-prediction-capability-of-stress-echocardiography
#7
Lauro Cortigiani, Clara Carpeggiani, Rosa Sicari, Claudio Michelassi, Francesco Bovenzi, Eugenio Picano
OBJECTIVES: To assess the value of a simple score integrating non-ischaemia-related variables in expanding the wall motion abnormalities risk power during stress echocardiography (SE). METHODS: Study includes 14 279 patients who underwent SE for evaluation of coronary artery disease. All-cause death was the end point. Patients were randomly divided into the modelling and validation group of equal size. In the modelling group, multivariate analysis was conducted using clinical, rest and SE data, and a score was obtained from the number of non-ischaemia-related independent prognostic predictors...
October 14, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29031929/permanent-his-bundle-pacing-as-an-alternative-to-biventricular-pacing-for-cardiac-resynchronization-therapy-a-multi-center-experience
#8
Parikshit S Sharma, Gopi Dandamudi, Bengt Herweg, David Wilson, Rajeev Singh, Angela Naperkowski, Jayanthi N Koneru, Kenneth A Ellenbogen, Pugazhendhi Vijayaraman
INTRODUCTION: Cardiac resynchronization therapy (CRT) using biventricular pacing (BVP) is effective in patients with heart failure, bundle branch block (BBB) or right ventricular pacing. Permanent His bundle pacing (HBP) has been reported as an alternative option for CRT. OBJECTIVE: The aim of the study was to assess the feasibility and outcomes of HBP in CRT eligible or failed patients. METHODS: HBP was attempted as a rescue strategy in patients with failed LV lead or non-response to BVP (Group I); or as a primary strategy in patients with AV block, BBB, or high ventricular pacing burden as an alternative to BVP (Group II) in patients with indications for CRT...
October 11, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29031415/usefulness-of-the-crt-score-for-shared-decision-making-in-cardiac-resynchronization-therapy-in-patients-with-a-left-ventricular-ejection-fraction-of-%C3%A2-35
#9
Ulas Höke, Bart Mertens, Mand J H Khidir, Martin J Schalij, Jeroen J Bax, Victoria Delgado, Nina Ajmone Marsan
Individualized estimation of prognosis after cardiac resynchronization therapy (CRT) remains challenging. Our aim was to develop a multiparametric prognostic risk score (CRT-SCORE) that could be used for patient-specific clinical shared decision making about CRT implantation. The CRT-SCORE was derived from an ongoing CRT registry, including 1,053 consecutive patients (age 67 ± 10 years, 76% male). Using preimplantation variables, 100 multiple imputed datasets were generated for model calibration. Based on multivariate Cox regression models, cross-validated linear prognostic scores were calculated, as well as survival fractions at 1 and 5 years...
August 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29030013/outcomes-of-patients-at-estimated-low-surgical-risk-undergoing-transcatheter-aortic-valve-implantation-with-balloon-expandable-prostheses
#10
Leire Unzué, Eulogio García, Rodrigo Teijeiro, Belén Díaz Antón, Miguel Rodríguez Del Río, Jorge Solís, Belen Rubio Alonso, Juan Medina, Francisco José Rodríguez Rodrigo, Francisco Javier Parra
INTRODUCTION AND OBJECTIVES: Transcatheter aortic-valve implantation (TAVI) is an accepted treatment for patients with severe aortic stenosis and high surgical risk. However, there is lack in data about TAVI in low-risk patients that are already being treated with this therapy in some clinical contexts. METHODS: A retrospective analysis of patients treated with transfemoral TAVI using Edwards Sapien prosthesis in one center was performed, classifying the patients into three groups according to the surgical risk (high/intermediate/low risk for STS score>8/4-8/<4)...
August 30, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29029965/contemporary-epidemiology-management-and-outcomes-of-patients-hospitalized-for-heart-failure-in-china-results-from-the-china-heart-failure-china-hf-registry
#11
Yuhui Zhang, Jian Zhang, Javed Butler, Xiaomin Yang, Peiyi Xie, Dongshuang Guo, Tiemin Wei, Jing Yu, Zhenli Wu, Yingchun Gao, Xiumin Han, Xuelian Zhang, Susheng Wen, Stefan D Anker, Gerasimos Filippatos, Gregg C Fonarow, Tianyi Gan, Rongcheng Zhang
BACKGROUND: Contemporary data on the epidemiology of heart failure (HF) in China are scarce. The China HF Registry was designed to investigate clinical characteristics, management, and outcomes of patients hospitalized for HF in China. DESIGN AND SUBJECTS: Data were collected prospectively on 13687 patients with a primary discharge diagnosis of HF who were enrolled from 132 participating hospitals between January 2012 to September 2015. Data from the China HF registry was compared with previously published literature...
October 10, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29028640/coronary-sinus-catheter-induced-heart-block-during-aortic-valve-replacement-a-case-report
#12
Aaron B Dahl, Teresa Murray-Torres, Daniel A Emmert
Conduction abnormalities after cardiac surgery are common as is spontaneous resolution of these abnormalities. However, 1%-3% of patients will require placement of a permanent pacemaker. Patients with preexisting conduction abnormalities, undergoing reoperation, preexisting pulmonary hypertension and undergoing mitral or aortic valve operations are at a higher risk for requiring a permanent pacemaker. We present the first case described in the literature of a patient with a preexisting left bundle branch block, and heart failure with a reduced left ventricular ejection fraction of 25% who developed complete heart block after placement of a coronary sinus catheter...
October 12, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29025777/oesophageal-ischaemia-an-uncommon-cause-of-chest-pain
#13
Ayodele Sasegbon, Akram Algieder, Bashir Rameh
A 79-year-old woman with a history of ischaemic heart disease and atrial fibrillation presented to hospital with severe chest pain. Blood tests showed an elevated D-dimer and a rise in troponin I. ECG showed right bundle branch block pattern and T wave inversion in leads V1 to V3, although these changes were present in old ECGs. A chest X-ray was done which was normal. Due to the nature and severity of her pain a CT aortic angiogram was done. This did not show any evidence of aortic dissection or a pulmonary embolism...
October 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29021860/atriofascicular-mahaim-with-ebstein-anomaly-a-case-report
#14
Kazushi Ueshima, Yoshihide Nakamura, Satoru Takeno, Toshiharu Miyake, Tsukasa Takemura
We report a case of a 7-year-old girl with atriofascicular Mahaim (AFM) pathway concomitant with Ebstein's anomaly. The QRS wave showed left bundle branch block pattern on electrocardiogram. Holter electrocardiogram showed prolongation of the PR interval and QRS morphological change during sinus tachycardia. An electrophysiological study demonstrated that the distal His potential appeared earlier than the proximal His potential, which suggested retrograde His conduction toward the atrioventricular node. Conduction from the Mahaim fiber to the His bundle was faster than that from the atrioventricular node towards the His bundle...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29021090/rbbb-tachycardia-with-north-west-axis-what-is-the-mechanism
#15
Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Sreevilasam Pushpangadhan Abhilash, Ajitkumar Valaparambil
RBBB tachycardia with NW axis is considered to be VT unless proved otherwise. However underlying conduction system disease can produce electrocardiographic patterns suggestive of bundle branch block with extreme left axis which can cause difficulty in differentiating VT from SVT as in this case.
September 1, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29019518/prevalence-and-predictive-value-of-electrocardiographic-abnormalities-in-pulmonary-hypertension-evidence-from-the-pan-african-pulmonary-hypertension-cohort-papuco-study
#16
Irina Balieva, Anastase Dzudie, Friedrich Thienemann, Ana O Mocumbi, Kamilu Karaye, Mahmoud U Sani, Okechukwu S Ogah, Adriaan A Voors, Andre Pascal Kengne, Karen Sliwa
BACKGROUND: Pulmonary hypertension (PH) is prevalent in Africa and is still often diagnosed only at an advanced stage, therefore it is associated with poor quality of life and survival rates. In resource-limited settings, we assessed the diagnostic utility of standard 12-lead electrocardiograms (ECG) to detect abnormalities indicating PH. METHODS: Sixty-five patients diagnosed with PH were compared with 285 heart disease-free subjects. The prevalence and diagnostic performance of ECG features indicative of PH and right heart strain were calculated...
October 11, 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/29018647/burden-of-arrhythmias-in-epilepsy-patients-a-nationwide-inpatient-analysis-of-1-4-million-hospitalizations-in-the-united-states
#17
Rupak Desai, Chintan Rupareliya, Upenkumar Patel, Syeda Naqvi, Smit Patel, Abhishek Lunagariya, Zabeen Mahuwala
Arrhythmias have been one of the common complications in epilepsy patients and have also been the reason for death. However, limited data exist about the burden and outcomes of arrhythmias by subtypes in epilepsy. Our study aims at evaluating the burden and differences in outcomes of various subtypes of arrhythmias in epilepsy patient population. The Nationwide Inpatient Sample (NIS) database from 2014 was examined for epilepsy and arrhythmias related discharges using appropriate International Classification of Disease, Ninth Revision Clinical Modification (ICD-9-CM) codes...
August 8, 2017: Curēus
https://www.readbyqxmd.com/read/29017215/-pulmonary-embolism-despite-rivaroxaban-in-an-obese-patient
#18
Thomas Schuh, Claudia Stöllberger
Introduction Rivaroxaban, an oral factor Xa inhibitor, is approved for therapy of venous thromboembolism. It is unclear whether the standard dose for patients with a body mass index (BMI) > 40 kg/m(2) is sufficient. History The 45-year-old patient was admitted because of increasing respiratory distress. She had a history of pulmonary embolism 30 months before the admission, a factor V Leiden mutation and several hospitalisations due to dermatomycoses. The patient briefly took phenprocoumon which was changed to 20 mg rivaroxaban due to a lack of adherence...
October 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28990972/managing-chest-pain-in-patients-with-concomitant-left-bundle-branch-block
#19
Andrew Wyant, Somu Chatterjee, Tamara Bennett
Diagnosis and timely management of acute myocardial infarction (MI) relies heavily on the ST-segment elevation sum. Presence of concomitant left bundle-branch block (LBBB) in patients presenting with possible acute MI presents a diagnostic dilemma. The LBBB pattern distorts ST-segment changes, delaying or preventing accurate diagnosis. This article reviews the Sgarbossa criteria and ST/S ratio and presents a treatment algorithm that may help improve patient care and reduce morbidity and mortality.
October 5, 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28983169/left-atrium-in-cardiac-resynchronization-therapy-active-participant-or-innocent-bystander
#20
Haitham A Badran, M A Abdelhamid, Mazen T Ibrahim, Ayman M Abdelmoteleb, John K Zarif
BACKGROUND: Cardiac resynchronization therapy (CRT) is an established treatment for patients with advanced heart failure that results in improvement of left ventricle (LV) systolic function and LV reverse remodeling. This may have a positive effect on the size and the function of the left atrium (LA). We assessed the LA function, dimensions, and volumes before and after CRT implantation. METHODS: A total of 37 patients with mean age of 55.3 ± 9.64 years including 11 (29...
October 2017: Journal of the Saudi Heart Association
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