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psoriasis atherosclerosis pet ct

Tsion M Aberra, Aditya A Joshi, Joseph B Lerman, Justin A Rodante, Asha K Dahiya, Heather L Teague, Qimin Ng, Joanna I Silverman, Alexander V Sorokin, Taufiq Salahuddin, Benjamin N Lockshin, Mark A Ahlman, Martin P Playford, Marcus Y Chen, Joel M Gelfand, Nehal N Mehta
BACKGROUND AND AIMS: Psoriasis is a chronic inflammatory disorder associated with vascular inflammation, measured by 18-fluorodeoxyglucose positron emission tomography/computed tomography (18-FDG PET/CT), and an increased risk of myocardial infarction. Patients with psoriasis are also more likely to suffer from comorbid depression. Whether depression accelerates the development of subclinical atherosclerosis in psoriasis is unknown. METHODS: Patients were selected from within a larger psoriasis cohort...
August 2016: Atherosclerosis
Shawn Rose, Jenny Dave, Corina Millo, Haley B Naik, Evan L Siegel, Nehal N Mehta
INTRODUCTION: Psoriasis and psoriatic arthritis (PsA) increase cardiovascular disease (CVD) risk, but surrogate markers for CVD in these disorders are inadequate. Because the presence of sacroiliitis may portend more severe PsA, we hypothesized that sacroiliitis defined by computed tomography (CT) would be associated with increased vascular inflammation defined by 18-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT), which is an established measure of CVD...
July 30, 2014: Arthritis Research & Therapy
Shawn Rose, Nikhil H Sheth, Joshua F Baker, Alexis Ogdie, Anna Raper, Babak Saboury, Thomas J Werner, Preethi Thomas, Abby Vanvoorhees, Abass Alavi, Drew A Torigian, Joel M Gelfand, Nehal N Mehta
OBJECTIVE: Psoriasis (PSO) and rheumatoid arthritis (RA) increase cardiovascular diseases (CVD) beyond traditional risk factors. Vascular inflammation has previously been demonstrated to be present in PSO and RA using [18F]-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) imaging. However, vascular inflammation has not been compared in these two disorders relative to a healthy reference population. Thus, vascular inflammation was quantitatively assessed in patients with PSO (n=10), RA (n=5), and healthy subjects (n=10) using FDG-PET/CT...
2013: American Journal of Cardiovascular Disease
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