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https://www.readbyqxmd.com/read/28931169/effect-of-educational-package-on-lifestyle-of-primiparous-mothers-during-postpartum-period-a-randomized-controlled-clinical-trial
#1
Farzaneh Khodabandeh, Mojgan Mirghafourvand, Mahin KamaliFard, Sakineh Mohammad-Alizadeh-Charandabi, Mohammad Asghari Jafarabadi
A healthy lifestyle is important for mothers during the postpartum period. This study was conducted to determine the effects of a lifestyle educational package in primiparous women. This randomized clinical trial was conducted on 220 mothers assigned to two groups using block randomization. In the intervention group, the mothers received face-to-face, phone and SMS counseling and a booklet in addition to routine postpartum training; in the control group, the mothers received only routine training. The Health Behaviors Questionnaire, a Food Frequency Questionnaire and the International Physical Activity Questionnaire were used for data collection...
October 1, 2017: Health Education Research
https://www.readbyqxmd.com/read/28929501/accommodating-the-ecological-fallacy-in-disease-mapping-in-the-absence-of-individual-exposures
#2
Feifei Wang, Jian Wang, Alan Gelfand, Fan Li
In health exposure modeling, in particular, disease mapping, the ecological fallacy arises because the relationship between aggregated disease incidence on areal units and average exposure on those units differs from the relationship between the event of individual incidence and the associated individual exposure. This article presents a novel modeling approach to address the ecological fallacy in the least informative data setting. We assume the known population at risk with an observed incidence for a collection of areal units and, separately, environmental exposure recorded during the period of incidence at a collection of monitoring stations...
September 19, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28928549/efficacy-of-tramadol-or-dexamethasone-as-an-adjuvant-to-levobupivacaine-in-ultrasound-guided-supraclavicular-plexus-block-for-upper-limb-surgery-a-randomized-double-blinded-controlled-study
#3
S Aravind Raj, Dewan Roshan Singh, S Antony John Charles, N Krishnaveni
AIMS AND OBJECTIVES: To evaluate the efficacy of tramadol or dexamethasone as an adjuvant to levobupivacaine in ultrasound-guided supraclavicular brachial plexus block in terms of onset time of complete sensory and motor blockade, duration of motor blockade, duration of analgesia, and any complication. SETTINGS AND DESIGN: This was a randomized controlled trial conducted in the Department of Anesthesiology, a tertiary care hospital. MATERIALS AND METHODS: Sixty consecutive patients of the American Society of Anesthesiologists physical status Class I and II who were posted for upper limb surgeries were recruited...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28928548/a-prospective-comparative-observational-study-of-clinical-efficacy-of-isobaric-ropivacaine-0-75-with-of-isobaric-bupivacaine-0-5-intrathecally-in-elective-inguinal-hernia-repair-surgeries
#4
Shivam Bipin Parekh, Suchita Shailesh Parikh, Harsha Patel, Malini Mehta
AIMS: To evaluate the efficacy of intrathecal isobaric Ropivacaine and its comparison with intrathecal isobaric Bupivacaine in elective inguinal hernia repair surgeries. SETTINGS AND DESIGN: A prospective, randomized study was conducted in a tertiary care hospital with 80 patients of ASA grade I-III undergoing elective inguinal hernia repair surgery under spinal anaesthesia. Ethical committee clearance and written consent taken. The patients were randomly divided into two equal groups to the Ropivicaine group (Group R) and to theBupivicaine group (Group B)...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28927240/temporal-dynamics-of-hippocampal-and-medial-prefrontal-cortex-interactions-during-the-delay-period-of-a-working-memory-guided-foraging-task
#5
Maxym Myroshnychenko, Jeremy K Seamans, Anthony G Phillips, Christopher C Lapish
Connections between the hippocampus (HC) and medial prefrontal cortex (mPFC) are critical for working memory; however, the precise contribution of this pathway is a matter of debate. One suggestion is that it may stabilize retrospective memories of recently encountered task-relevant information. Alternatively, it may be involved in encoding prospective memories, or the internal representation of future goals. To explore these possibilities, simultaneous extracellular recordings were made from mPFC and HC of rats performing the delayed spatial win-shift on a radial maze...
September 12, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28925405/intermittent-energy-restriction-improves-weight-loss-efficiency-in-obese-men-the-matador-study
#6
N M Byrne, A Sainsbury, N A King, A P Hills, R E Wood
BACKGROUND/OBJECTIVES: The MATADOR (Minimising Adaptive Thermogenesis And Deactivating Obesity Rebound) study examined whether intermittent energy restriction (ER) improved weight loss efficiency compared with continuous ER and, if so, whether intermittent ER attenuated compensatory responses associated with ER. SUBJECTS/METHODS: Fifty-one men with obesity were randomised to 16 weeks of either: (1) continuous (CON), or (2) intermittent (INT) ER completed as 8 × 2-week blocks of ER alternating with 7 × 2-week blocks of energy balance (30 weeks total)...
August 17, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28924946/listeners-are-maximally-flexible-in-updating-phonetic-beliefs-over-time
#7
David Saltzman, Emily Myers
Perceptual learning serves as a mechanism for listenexrs to adapt to novel phonetic information. Distributional tracking theories posit that this adaptation occurs as a result of listeners accumulating talker-specific distributional information about the phonetic category in question (Kleinschmidt & Jaeger, 2015, Psychological Review, 122). What is not known is how listeners build these talker-specific distributions; that is, if they aggregate all information received over a certain time period, or if they rely more heavily upon the most recent information received and down-weight older, consolidated information...
September 18, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28924735/the-g-protein-coupled-estrogen-receptor-gper-gpr30-may-serve-as-a-prognostic-marker-in-early-stage-cervical-cancer
#8
Klaus Friese, Bernd Kost, Aurelia Vattai, Frederik Marmé, Christina Kuhn, Sven Mahner, Christian Dannecker, Udo Jeschke, Sabine Heublein
BACKGROUND: Estrogen signalling is transmitted via various receptors and multiple intracellular signalling pathways. Estrogen receptor alpha (ERα)-mediated transcription of target genes has been demonstrated to be closely linked to human papilloma virus (HPV)-induced carcinogenesis in case of cervical cancer. So far, the role of non-genomic estrogen signals in cervical cancer, e.g. transmitted by the G protein-coupled estrogen receptor (GPER) remains to be rather elusive. Today's knowledge on the role of GPER in cervical cancer is sparse and-to the best of our knowledge-GPER has not been investigated in context with clinicopathological parameters or prognosis of cervical cancer...
September 18, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28922231/use-of-regional-anesthesia-for-outpatient-surgery-within-the-united-states-a-prevalence-study-using-a-nationwide-database
#9
Rodney A Gabriel, Brian M Ilfeld
BACKGROUND: Regional anesthesia is of benefit for outpatient surgery given its demonstrated improvement in analgesia and decrease in complications, resulting in shorter average recovery room times and lower hospital readmission rates. Unfortunately, there are few epidemiological studies outlining the overall utilization of peripheral nerve blocks (PNBs) in this setting. Therefore, the primary objective of this study was to report the overall utilization of several types of PNBs among all candidate cases in the outpatient setting within the United States...
September 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28922230/optimal-dose-of-perineural-dexamethasone-to-prolong-analgesia-after-brachial-plexus-blockade-a-systematic-review-and-meta-analysis
#10
Kyle Robert Kirkham, Alain Jacot-Guillarmod, Eric Albrecht
BACKGROUND: Perineural dexamethasone has gained popularity in regional anesthesia to prolong analgesia duration. However, uncertainty remains regarding the optimal perineural dose. Clarification of this characteristic is of significant importance as the administration of dexamethasone may lead to dose-dependent complications. The objective of this meta-analysis was to define the optimal perineural dexamethasone dose to prolong analgesia after brachial plexus blockade for adult patients undergoing upper limb surgery...
September 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28919557/synergistic-effects-of-dendritic-cell-targeting-and-laser-microporation-on-enhancing-epicutaneous-skin-vaccination-efficacy
#11
Yoan Machado, Sanne Duinkerken, Veronika Hoepflinger, Melissa Mayr, Evgeniia Korotchenko, Almedina Kurtaj, Isabel Pablos, Markus Steiner, Angelika Stoecklinger, Joyce Lübbers, Maximillian Schmid, Uwe Ritter, Sandra Scheiblhofer, Michael Ablinger, Verena Wally, Sarah Hochmann, Anna M Raninger, Dirk Strunk, Yvette van Kooyk, Josef Thalhamer, Richard Weiss
Due to its unique immunological properties, the skin is an attractive target tissue for allergen-specific immunotherapy. In our current work, we combined a dendritic cell targeting approach with epicutaneous immunization using an ablative fractional laser to generate defined micropores in the upper layers of the skin. By coupling the major birch pollen allergen Bet v 1 to mannan from S. cerevisiae via mild periodate oxidation we generated hypoallergenic Bet-mannan neoglycoconjugates, which efficiently targeted CD14+ dendritic cells and Langerhans cells in human skin explants...
September 14, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28918643/speech-language-pathology-telehealth-in-rural-and-remote-schools-the-experience-of-school-executive-and-therapy-assistants
#12
Glenn C Fairweather, Michelle A Lincoln, Robyn Ramsden
INTRODUCTION: Difficulties in accessing allied health services, especially in rural and remote areas, appear to be driving the use of telehealth services to children in schools. The objectives of this study were to investigate the experiences and views of school executive staff and therapy assistants regarding the feasibility and acceptability of a speech-language pathology telehealth program for children attending schools in rural and remote New South Wales, Australia. The program, called Come N See, provided therapy interventions remotely via low-bandwidth videoconferencing, with email follow-up...
July 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28916322/intraductal-transanastomotic-stenting-in-duct-to-duct-biliary-reconstruction-after-living-donor-liver-transplantation-a-randomized-trial
#13
Ky Santosh Kumar, Johns Shaji Mathew, Dinesh Balakrishnan, Viju Kumar Bharathan, Binoj Sivasankara Pillai Thankamony Amma, Unnikrishnan Gopalakrishnan, Ramachandran Narayana Menon, Puneet Dhar, Sudheer Othiyil Vayoth, Sudhindran Surendran
BACKGROUND: Biliary complications continue to be the 'Achilles heel' of living donor liver transplantation (LDLT). The use of biliary stents in LDLT to reduce biliary complication is a controversial issue. We performed a randomized trial to study the impact of intraductal biliary stents on postoperative biliary complications following LDLT. STUDY DESIGN: Of the 94 LDLT's, that were performed during a period of 16 months, ABO incompatible transplants, left lobe grafts, ≥3 ducts on the graft and those requiring bilio-enteric drainage were excluded...
September 12, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28914439/dampness-heat-accelerates-dmba-induced-mammary-tumors-in-rats
#14
Wei Dong, Xi-Lan Tang, Guang-Bin Shang, Guo-Liang Xu, Wei-Feng Zhu, Hong-Ning Liu
OBJECTIVE: To investigate the impact of dampness-heat (DH) on the development of mammary tumors in 7,12-dimethylbenz(a)anthracene (DMBA)-induced rats. METHODS: Forty rats were randomly divided into 3 groups in a randomized block design, including the control group (n=13), DMBA group (n=14), and DMBA plus DH group (n=13). Rats in the DMBA group and DMBA plus DH group were intragastrically administrated with DMBA (100 mg/kg) for twice, once per week, while rats in the control group were treated with equivalent volumes of sesame oil...
September 15, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28913921/analgesic-efficacy-of-local-infiltration-analgesia-vs-femoral-nerve-block-after-anterior-cruciate-ligament-reconstruction-a-systematic-review-and-meta-analysis
#15
REVIEW
K R Kirkham, S Grape, R Martin, E Albrecht
Many published reports consider blockade of the femoral nerve distribution the best available analgesic treatment after anterior cruciate ligament reconstruction. However, some argue that an alternative approach of infiltrating local anaesthetic into the surgical site has similar efficacy. The objectives of this meta-analysis were to compare the analgesic and functional outcomes of both treatments following anterior ligament reconstruction. The primary outcomes were pain scores at rest (analogue scale, 0-10) in the early (0-2 postoperative hours), intermediate (3-12 hours) and late postoperative periods (13-24 hours)...
September 15, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28911883/tnf-superfamily-member-april-enhances-midbrain-dopaminergic-axon-growth-and-contributes-to-the-nigrostriatal-projection-in-vivo
#16
Thomas G McWilliams, Laura Howard, Sean Wyatt, Alun M Davies
We have studied the role of the tumor necrosis factor superfamily member APRIL in the development of embryonic mouse midbrain dopaminergic neurons in vitro and in vivo. In culture, soluble APRIL enhanced axon growth during a window of development between E12 and E14 when nigrostriatal axons are growing to their targets in the striatum in vivo. April transcripts were detected in both the striatum and midbrain during this period and at later stages. The axon growth-enhancing effect of APRIL was similar to that of glial cell-derived neurotrophic factor (GDNF), but in contrast to GDNF, APRIL did not promote the survival of midbrain dopaminergic neurons...
September 11, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28911334/slow-release-praziquantel-for-dogs-presentation-of-a-new-formulation-for-echinococcosis-control
#17
Bin Jiang, Xiao-Nong Zhou, Hao-Bing Zhang, Yi Tao, Le-Le Huo, Ni Liu
BACKGROUND: Echinococcosis is a serious, zoonotic, parasitic disease with worldwide distribution. According to a epidemiological survey in 2012 in China, there are 20,000 infected patients and more than 50 million people at the risk. As the dog is the main, definitive host, the Government of China encourages monthly praziquantel treatment of every dog. However, this is difficult to achieve in geographically challenging areas, such as the Tibetan plateau, where there are also many dogs without owners...
September 15, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28911305/alginate-based-cell-microencapsulation-for-tissue-engineering-and-regenerative-medicine
#18
Vittoria Pandolfi, Ulysse Pereira, Murielle Dufresne, Cécile Legallais
Increasing numbers of requests for transplantable organs and their scarcity has led to a pressing need to find alternative solutions to standard transplantation. An appealing but challenging proposal came from the fields of tissue engineering and regenerative medicine, the purpose of which is to build tissues/organs from scratch in the laboratory and use them as either permanent substitutes for direct implantation into the patient's body, or as temporary substitutes to bridge patients until organ regeneration or transplantation...
June 8, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28904659/-pulmonary-embolism-at-the-university-hospital-campus-of-lome-togo-a-retrospective-study-about-51-cases
#19
Soulemane Pessinaba, Yaovi Dodzi Molba Atti, Soodougoua Baragou, Machihude Pio, Yaovi Afassinou, Mohamed Kpélafia, Edem Goeh-Akué, Findibé Damorou
INTRODUCTION: This study provides an analysis of the evolutionary, clinical and epidemiological aspects of pulmonary embolism at the University Hospital Campus of Lome. METHODS: We conducted a retrospective, analytic and descriptive study over a period of 39 months (November 1 , 2011- January 31, 2015). All the medical records of patients hospitalized for PE in the Department of Cardiology at the University Hospital Campus were analyzed. RESULTS: The prevalence of PE was 3...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28901011/persistent-aberrant-cortical-phase-amplitude-coupling-following-seizure-treatment-in-absence-epilepsy-models
#20
Atul Maheshwari, Abraham Akbar, Mai Wang, Rachel Marks, Katherine Yu, Suhyeorn Park, Brett L Foster, Jeffrey L Noebels
In childhood absence epilepsy, cortical seizures are brief and intermittent; however there are extended periods without behavioural or electrographic ictal events. This genetic disorder is associated with variable degrees of cognitive dysfunction, but no consistent functional biomarkers that might provide insight into interictal cortical function have been described. Previous work in monogenic mouse models of absence epilepsy have shown that the interictal EEG displays augmented beta/gamma power in homozygous stargazer (stg/stg) mice bearing a presynaptic AMPA receptor defect, but not homozygous tottering (tg/tg) mice with a P/Q type calcium channel mutation...
September 12, 2017: Journal of Physiology
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