keyword
https://read.qxmd.com/read/38537020/surface-treatments-of-the-zirconia-reinforced-lithium-disilicate-ceramic-in-the-adhesion-to-the-resin-cement
#1
JOURNAL ARTICLE
Mirko A R Aguilera, Américo C Bortolazzo, Lourenço Correr-Sobrinho, Rafael L X Consani
This study verified the effect of surface treatments of the zirconia-reinforced lithium disilicate ceramic bonded to resin cement. Ceramic blocks were divided according to treatments (n=10): FA+SRX (Fluoric acid + silane RX), FA+MDP (Fluoric acid + MDP), FA+SCF+MDP (Fluoric acid + silane CF + MDP), FA+MEP (Fluoric acid + MEP), and MEP (Self-etch primer). Resin cement cylinders were made in the ceramic blocks, photoactivated with 1,200 mW/cm² for 40s, stored in water at 37°C for 24h, and evaluated by the microshear strength test, optical failure descriptive analysis (%), surface characterization (SEM) and contact angle (Goniometer)...
2024: Brazilian Dental Journal
https://read.qxmd.com/read/38536479/applying-machine-learning-in-the-investigation-of-the-link-between-the-high-velocity-streams-of-charged-solar-particles-and-precipitation-induced-floods
#2
JOURNAL ARTICLE
Slavica Malinović-Milićević, Yaroslav Vyklyuk, Milan M Radovanović, Milan Milenković, Ana Milanović Pešić, Boško Milovanović, Teodora Popović, Petro Sydor, Marko D Petrović
This study explores a possible link between solar activity and floods caused by precipitation. For this purpose, discrete blocks of data for 89 separate flood events in Europe in the period 2009-2018 were used. Solar activity parameters with a time lag of 0-11 days were used as input data of the model, while precipitation data in the 12 days preceding the flood were used as output data. The level of randomness of the input and output time series was determined by correlation analysis, while the potential causal relationship was established by applying machine learning classification predictive modeling...
March 27, 2024: Environmental Monitoring and Assessment
https://read.qxmd.com/read/38536037/effects-of-follicle-stimulating-hormone-on-energy-balance-and-tissue-metabolic-health-after-loss-of-ovarian-function
#3
JOURNAL ARTICLE
Andrew E Libby, Claudia Solt, Matthew Jackman, Vanessa Sherk, Rebecca M Foright, Ginger C Johnson, Thi-Tina Nguyen, Matthew Breit, Nicholas Hulett, Michael Rudolph, Paul A Roberson, Elizabeth Wellberg, Purevsuren Jambal, Rebecca L Scalzo, Janine Higgins, T Rajendra Kumar, Margaret E Wierman, Zhaoxing Pan, Kartik Shankar, Dwight J Klemm, Kerrie L Moreau, Wendy M Kohrt, Paul S MacLean
Loss of ovarian function imparts increased susceptibility to obesity and metabolic disease. These effects are largely attributed to decreased estradiol (E2 ), but the role of increased follicle stimulating hormone (FSH) in modulating energy balance has not been fully investigated. Previous work that blocked FSH binding to its receptor in mice suggested this hormone may play a part in modulating body weight and energy expenditure after ovariectomy. We used an alternate approach to isolate the individual and combined contributions of FSH and E2 in mediating energy imbalance and changes in tissue-level metabolic health...
March 27, 2024: American Journal of Physiology. Endocrinology and Metabolism
https://read.qxmd.com/read/38535243/enhancing-the-antifouling-properties-of-alumina-nanoporous-membranes-by-go-mof-impregnated-polymer-coatings-in-vitro-studies
#4
JOURNAL ARTICLE
Mona Moaness, Sara A M El-Sayed, Hanan H Beherei, Mostafa Mabrouk
Nanoporous membranes (NPMBs) have been the focus of interest of many scientists in the last decade. However, the fouling phenomenon that takes place during the implantation period blocks pores and causes failure in the local implant. In this study, alumina NPMBs were developed using electrochemical anodization through two steps. Furthermore, graphene oxide (GO), free and impregnated with ZIF-8 MOF, was synthesized and loaded in a mixture of PVDF/PVP polymer matrix at different ratios, and was applied to the produced NPMBs using spin-coater...
February 20, 2024: Journal of Functional Biomaterials
https://read.qxmd.com/read/38534273/mandibular-endochondral-growth-is-specifically-augmented-by-nutritional-supplementation-with-myo-inositol-even-in-rabbits
#5
JOURNAL ARTICLE
Miho Shimoyama, Hiroyuki Kanzaki, Syunnosuke Tohyama, Tomomi Ida, Misao Ishikawa, Yuta Katsumata, Chihiro Arai, Satoshi Wada, Shugo Manase, Hiroshi Tomonari
Mandibular retrognathism occurs by insufficient mandibular growth and causes several issues, such as respiratory difficulty and diminished masticatory function. At present, functional orthodontic appliances are used for stimulating mandibular growth in pediatric cases. However, the effectiveness of functional appliances is not always stable in daily practices. A more effective, reliable, and safer therapeutic method for mandibular growth promotion would be helpful for growing mandibular retrognathism patients...
February 26, 2024: Dentistry Journal
https://read.qxmd.com/read/38534191/patient-access-of-their-radiology-reports-before-and-after-implementation-of-21st-century-cures-act-information-blocking-provisions-at-a-large-multicampus-health-system
#6
JOURNAL ARTICLE
Jordan R Pollock, Skye A Buckner Petty, John J Schmitz, Jacob Varner, Allie M Metcalfe, Nelly Tan
Background: To implement provisions of the 21st Century Cures Act addressing information blocking, federal regulations mandated that health systems provide patients with immediate access to elements of their electronic health information, including imaging results. Objective: To compare patient access of radiology reports before and after implementation of the information-blocking provisions of the 21st Century Cures Act. Method: This retrospective study included patients who underwent outpatient imaging examinations from January 1, 2021, to December 31, 2022 at three campuses within a large health system...
March 27, 2024: AJR. American Journal of Roentgenology
https://read.qxmd.com/read/38533639/cardiac-gr-mediates-the-diurnal-rhythm-in-ventricular-arrhythmia-susceptibility
#7
JOURNAL ARTICLE
Roman Tikhomirov, Robert H Oakley, Cali Anderson, Yirong Xiang, Sami Al Othman, Matthew Smith, Sana Yaar, Eleonora Torre, Jianying Li, Leslie R Wilson, David R Goulding, Ian Donaldson, Erika Harno, Luca Soattin, Holly A Shiels, Gwilym M Morris, Henggui Zhang, Mark R Boyett, John A Cidlowski, Pietro Mesirca, Matteo E Mangoni, Alicia D'Souza
RATIONALE: Ventricular arrhythmias (VAs) demonstrate a prominent day-night rhythm, commonly presenting in the early morning. Transcriptional rhythms in cardiac ion channels accompany this phenomenon, but their role in the morning vulnerability to VAs and the underlying mechanisms are not understood. OBJECTIVE: The objectives are to investigate the recruitment of transcription factors to time-of-day differentially accessible chromatin that underpins day-night ion channel rhythms and to assess the significance of this for the heart's day-night rhythm in VA susceptibility...
March 27, 2024: Circulation Research
https://read.qxmd.com/read/38531283/quadratus-lumborum-block-vs-transversus-abdominis-plane-block-for-postoperative-pain-control-in-patients-with-nephrectomy-a-systematic-review-and-network-meta-analysis
#8
REVIEW
Tianyu Gao, Yigang Wang, Yuxin Zheng, Yonghao Yu, Qing Li, Linlin Zhang
STUDY OBJECTIVE: This systematic review and network meta-analysis aimed to compare the analgesic efficacy of transversus abdominis plane block (TAPB) and quadratus lumborum block (QLB) on nephrectomy. DESIGN: Systematic review and network meta-analysis. PATIENTS: Patients undergoing nephrectomy. INTERVENTIONS: TAPB and QLB for postoperative analgesia. MEASUREMENTS: The primary outcome was 24 h morphine-equivalent consumptions after surgery...
March 25, 2024: Journal of Clinical Anesthesia
https://read.qxmd.com/read/38530780/effects-of-interleukin-6-signal-inhibition-on-treg-subpopulations-and-association-of-tregs-with-clinical-outcomes-in-rheumatoid-arthritis
#9
JOURNAL ARTICLE
Hiroto Yoshida, Mayu Magi, Hiroya Tamai, Jun Kikuchi, Keiko Yoshimoto, Kotaro Otomo, Yoshihiro Matsumoto, Mariko Noguchi-Sasaki, Tsutomu Takeuchi, Yuko Kaneko
OBJECTIVES: Anti-IL-6 receptor antibodies are clinically efficacious in the management of rheumatoid arthritis (RA) with an associated increase in regulatory T cells (Tregs); however, the role of functional Treg subsets has yet to be clarified. This study aimed to evaluate how functional Treg subsets are altered by IL-6 receptor blockade and to analyze the relationship between these Treg subsets and the clinical outcome of RA. METHODS: We collected frozen peripheral blood mononuclear cells (PBMCs) from 40 patients with RA who started tocilizumab (TCZ) with or without MTX and 11 healthy controls (HCs)...
March 26, 2024: Rheumatology
https://read.qxmd.com/read/38530238/the-human-mif-polymorphism-catt-7-enhances-pro-inflammatory-macrophage-polarization-in-a-clinically-relevant-model-of-allergic-airway-inflammation
#10
JOURNAL ARTICLE
Hazel Dunbar, Ian J Hawthorne, Eóin N McNamee, Michelle E Armstrong, Seamas C Donnelly, Karen English
High level expression of the pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) has been associated with severe asthma. The role of MIF and its functional promotor polymorphism in innate immune training is currently unknown. Using novel humanized CATT7 MIF mice, this study is the first to investigate the effect of MIF on bone marrow-derived macrophage (BMDM) memory after house dust mite (HDM) challenge. CATT7 BMDMs demonstrated a significant primed increase in M1 markers following HDM and LPS stimulation, compared to naive mice...
March 31, 2024: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://read.qxmd.com/read/38530201/revealing-the-kinetic-phase-behavior-of-block-copolymer-complexes-using-solvent-vapor-absorption-desorption-isotherms
#11
JOURNAL ARTICLE
Nayanathara Hendeniya, Caden Chittick, Kaitlyn Hillery, Shaghayegh Abtahi, Curtis Mosher, Boyce Chang
Controlling the self-assembled morphologies in block copolymers heavily depends on their molecular architecture and processing conditions. Solvent vapor annealing is a versatile processive pathway to obtain highly periodic self-assemblies from high chi (χ) block copolymers (BCPs) and supramolecular BCP complexes. Despite the importance of navigating the energy landscape, controlled solvent vapor annealing (SVA) has not been investigated in BCP complexes, partly due to its intricate multicomponent nature...
March 26, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38529872/-neuropathy-in-n-hexane-poisoning
#12
JOURNAL ARTICLE
E S Druzhinina, A A Kozyreva, R T Bembeeva, A S Kozlovsky, V E Sokolova, I V Isaev, A G Narbutov, N N Zavadenko, O A Tikhonova
N-Hexane is a solvent widely used in manufacturing as a cleaner, degreaser and component of rubber cement. Chronic exposure to n -hexane either through contact with unprotected skin or inhalation can lead to the development of clinical symptoms and electrophysiological changes similar to those of inflammatory demyelinating polyneuropathy which requires careful differential diagnosis. This article presents three cases of severe predominantly motor polyneuropathy with demyelinating features in 15- and 16-year-old adolescents...
2024: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://read.qxmd.com/read/38527808/pp2b-dependent-cerebellar-plasticity-sets-the-amplitude-of-the-vestibulo-ocular-reflex-during-juvenile-development
#13
JOURNAL ARTICLE
Bin Wu, Laura Post, Zhanmin Lin, Martijn Schonewille
Throughout life, the cerebellum plays a central role in the coordination and optimization of movements, using cellular plasticity to adapt a range of behaviors. Whether these plasticity processes establish a fixed setpoint during development, or continuously adjust behaviors throughout life, is currently unclear. Here, by spatiotemporally manipulating the activity of protein phosphatase 2B (PP2B), an enzyme critical for cerebellar plasticity, in male and female mice, we examined the consequences of disrupted plasticity on the performance and adaptation of the vestibulo-ocular reflex (VOR)...
March 25, 2024: Journal of Neuroscience
https://read.qxmd.com/read/38527630/enhancing-walking-performance-in-patients-with-peripheral-arterial-disease-an-intervention-with-ankle-foot-orthosis
#14
JOURNAL ARTICLE
Farahnaz Fallahtafti, Kaeli Samson, Zahra Salamifar, Jason Johanning, Iraklis Pipinos, Sara A Myers
Lower extremity peripheral artery disease (PAD) is a cardiovascular condition manifesting from narrowed or blocked arteries supplying the legs. Gait is impaired in patients with PAD. Recent evidence suggests that walking with carbon fiber ankle foot orthoses (AFOs) can improve patient mobility and delay claudication time. This study aimed to employ advanced biomechanical gait analysis to evaluate the impact of AFO intervention on gait performance among patients with PAD. Patients with claudication had hip, knee, and ankle joint kinetics and kinematics assessed using a cross-over intervention design...
March 23, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38527508/-diagnosis-and-treatment-of-arrhythmogenic-cardiomyopathy-in-children
#15
JOURNAL ARTICLE
W Q Ye, Y Y Xiao, X K Jiang, M Jin, X F Wang, W W Ding
Objective: To summarize the clinical manifestations, experiences in diagnosis and treatment of arrhythmogenic cardiomyopathy (ACM) in children. Methods: A retrospective analysis of the clinical manifestations, laboratory tests, radiological features, treatment and follow-up results was conducted in 11 children diagnosed with ACM at the center of congenital heart disease, Beijing anzhen hospital from May 2010 to March 2022. Results: A total of 11 patients aged 2 to 16 years, including 5 males and 6 females were diagnosed with ACM...
March 25, 2024: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/38525114/six-week-postoperative-opioid-use-and-pain-following-a-randomized-controlled-trial-evaluating-multimodal-analgesia-for-head-and-neck-free-flap-patients
#16
JOURNAL ARTICLE
Sarah F Wagoner, Amelia S Lawrence, Rahul Alapati, Bryan Renslo, Chelsea S Hamill, Antonio Bon Nieves, Maraya Baumanis, Andrés M Bur, Kiran Kakarala, Kevin J Sykes, Yelizaveta Shnayder
INTRODUCTION: Head and neck malignancy treatment often involves invasive surgeries, necessitating effective postoperative pain control. However, chronic reliance on opioid medications remains a challenge for many patients after surgery. Multimodal analgesia (MMA) within enhanced recovery after surgery protocols has shown success in limiting narcotic pain medications for other cancer types. In a prior study, MMA comprising acetaminophen, ketorolac, gabapentin, and a neurogenic block reduced opioid use in the 7-day postoperative period for major head and neck reconstructive surgery...
April 2024: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/38524702/minimally-invasive-tibiotalocalcaneal-arthrodesis-with-blocked-retrograde-intramedullary-nail-report-of-three-cases
#17
JOURNAL ARTICLE
Fernando Delmonte Moreira, Jorge Eduardo de Schoucair Jambeiro, Antero Tavares Cordeiro, José Augusto Oliveira, Felipe Fernandes Leão, Alex Guedes
Ankle osteoarthritis (AOA) is associated with pain and variable functional limitation, demanding clinical treatment and possible surgical indication when conservative measures are ineffective - arthrodesis has been the procedure of choice, because it reduces pain, restores joint alignment and makes the segment stable, preserving gait. The present study reports 3 cases (3 ankles) of male patients between 49 and 63 years old, with secondary AOA, preoperative American Orthopaedic Foot and Ankle Society Ankle-Hindfoot Scale (AOFAS AHS) of 27 to 39 points, treated by minimally invasive tibiotalocalcaneal arthrodesis using blocked retrograde intramedullary nail...
February 2024: Revista Brasileira de Ortopedia
https://read.qxmd.com/read/38524689/thoracoscopic-intercostal-nerve-block-with-cocktail-analgesics-for-pain-control-after-video-assisted-thoracoscopic-surgery-a-prospective-cohort-study
#18
JOURNAL ARTICLE
Jue Li, Yingxian Dong, Jiawei Guo, Lei Wang, Jie Tian, Li Wang, Guowei Che
OBJECTIVE: To evaluate whether using a cocktail of intercostal nerve blocks (TINB) during thoracoscopic surgery results in better clinical outcomes than patient-controlled analgesia (PCIA). METHODS: Patients in two medical groups undergoing video-assisted thoracoscopic surgery (VATS) for pulmonary nodules in West China Hospital of Sichuan University were collected consecutively between March 2022 and December 2022. The groups were divided into two subgroups based on their analgesic program, which were TINB group and PCIA group...
2024: Journal of Pain Research
https://read.qxmd.com/read/38521301/poly-lactic-acid-composite-films-comprising-carvacrol-and-cellulose-nanocrystal-zinc-oxide-with-synergistic-antibacterial-effects
#19
JOURNAL ARTICLE
Hao Zheng, Lei Chen, Tianhao Liu, Mengyao Liu, Yueqiang Yang, Guoying Liu, Hangqi Zhao, Pengrui Chen, Shaotong Fu, Yanhua Zhang, Jun Shen
Herein, carvacrol (CRV) and modified cellulose nanocrystal-zinc oxide (CNC-ZnO) were incorporated into a poly (lactic acid) (PLA) matrix to prepare a PLA-based composite film using a simple solution casting method to achieve antimicrobial effects for application in antimicrobial food packaging. Compared with films obtained from neat PLA, the PLA@CRV20% @CNC-ZnO3% composite film shows better performance in terms of mechanical properties, ultraviolet (UV) blocking, and antimicrobial effects. The PLA composites containing CRV and 3 wt% CNC-ZnO blends exhibit improved tensile strength (21...
March 21, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38519888/the-effect-of-paracetamol-on-care-dependency-and-daily-functioning-in-persons-with-advanced-dementia-living-in-long-term-care-facilities
#20
RANDOMIZED CONTROLLED TRIAL
Paulien H van Dam, Wilco P Achterberg, Bettina S Husebo, Monique Aa Caljouw
BACKGROUND: Pain medication may have an impact on the quality of life (QoL) in persons with dementia, but may also influence care dependency and daily functioning. The aim of this study is to investigate the effect of regularly scheduled paracetamol on care dependency and daily functioning in persons with advanced dementia with low QoL living in long-term care facilities. METHODS: The Quality of life and Paracetamol In advanced Dementia (Q-PID) study was a (block) randomized double-blind placebo-controlled crossover trial with paracetamol and placebo across seventeen long-term care facilities across 9 care organizations in the western region of the Netherlands...
March 22, 2024: BMC Geriatrics
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