keyword
MENU ▼
Read by QxMD icon Read
search

Graphic medicine

keyword
https://www.readbyqxmd.com/read/28929446/new-imaging-tools-in-cardiovascular-medicine-computational-fluid-dynamics-and-4d-flow-mri
#1
Keiichi Itatani, Shohei Miyazaki, Tokoki Furusawa, Satoshi Numata, Sachiko Yamazaki, Kazuki Morimoto, Rina Makino, Hiroko Morichi, Teruyasu Nishino, Hitoshi Yaku
Blood flow imaging is a novel technology in cardiovascular medicine and surgery. Today, two types of blood flow imaging tools are available: measurement-based flow visualization including 4D flow MRI (or 3D cine phase-contrast magnetic resonance imaging), or echocardiography flow visualization software, and computer flow simulation modeling based on computational fluid dynamics (CFD). MRI and echocardiography flow visualization provide measured blood flow but have limitations in temporal and spatial resolution, whereas CFD flow calculates the flow according to assumptions instead of flow measurement, and it has sufficiently fine resolution up to the computer memory limit, and it enables even virtual surgery when combined with computer graphics...
September 19, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28916961/practical-computational-toolkits-for-dendrimers-and-dendrons-structure-design
#2
Nuno Martinho, Liana C Silva, Helena F Florindo, Steve Brocchini, Teresa Barata, Mire Zloh
Dendrimers and dendrons offer an excellent platform for developing novel drug delivery systems and medicines. The rational design and further development of these repetitively branched systems are restricted by difficulties in scalable synthesis and structural determination, which can be overcome by judicious use of molecular modelling and molecular simulations. A major difficulty to utilise in silico studies to design dendrimers lies in the laborious generation of their structures. Current modelling tools utilise automated assembly of simpler dendrimers or the inefficient manual assembly of monomer precursors to generate more complicated dendrimer structures...
September 15, 2017: Journal of Computer-aided Molecular Design
https://www.readbyqxmd.com/read/28914377/the-permeability-enhancing-mechanism-of-menthol-on-skin-lipids-a-molecular-dynamics-simulation-study
#3
Huanjie Wang, Fancui Meng
The stratum corneum (SC), the outermost layer of skin, represents the primary barrier to molecules penetrating the skin. Menthol is widely used in clinical medicine as a penetration enhancer due to its high efficiency and relative safety. In this study, molecular dynamics simulations have been performed to investigate the effect of menthol molecules on the structural and permeability of both single component and ternary mixed bilayers. The lipid matrix is modeled as pure ceramide (CER2) or as a 2:2:1 mixture of CER2, cholesterol (CHOL), and free fatty acid (FFA)...
September 15, 2017: Journal of Molecular Modeling
https://www.readbyqxmd.com/read/28874736/genfire-a-generalized-fourier-iterative-reconstruction-algorithm-for-high-resolution-3d-imaging
#4
Alan Pryor, Yongsoo Yang, Arjun Rana, Marcus Gallagher-Jones, Jihan Zhou, Yuan Hung Lo, Georgian Melinte, Wah Chiu, Jose A Rodriguez, Jianwei Miao
Tomography has made a radical impact on diverse fields ranging from the study of 3D atomic arrangements in matter to the study of human health in medicine. Despite its very diverse applications, the core of tomography remains the same, that is, a mathematical method must be implemented to reconstruct the 3D structure of an object from a number of 2D projections. Here, we present the mathematical implementation of a tomographic algorithm, termed GENeralized Fourier Iterative REconstruction (GENFIRE), for high-resolution 3D reconstruction from a limited number of 2D projections...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28869978/annals-graphic-medicine-dear-doctor-i
#5
K C Councilor
No abstract text is available yet for this article.
September 5, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28776063/challenges-and-perspectives-in-nucleic-acid-enzyme-engineering
#6
Darko Balke, Robert Hieronymus, Sabine Müller
Engineering of nucleic acids has been a goal in research for many years. Since the discovery of catalytic nucleic acids (ribozymes and DNAzymes), this field has attracted even more attention. One reason for the increased interest is that a large number of ribozymes have been engineered that catalyze a broad range of reactions of relevance to the origin of life. Another reason is that the structures of ribozymes or DNAzymes have been modulated such that activity is dependent on allosteric regulation by an external cofactor...
August 4, 2017: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/28766114/rapid-characterization-of-constituents-in-tribulus-terrestris-from-different-habitats-by-uhplc-q-tof-ms
#7
Wei Zheng, Fangxu Wang, Yang Zhao, Xinguang Sun, Liping Kang, Ziquan Fan, Lirui Qiao, Renyi Yan, Shuchen Liu, Baiping Ma
A strategy for rapid identification of the chemical constituents from crude extracts of Tribulus terrestris was proposed using an informatics platform for the UHPLC/Q-TOF MS(E) data analyses. This strategy mainly utilizes neutral losses, characteristic fragments, and in-house library to rapidly identify the structure of the compounds. With this strategy, rapid characterization of the chemical components of T. terrestris from Beijing, China was successfully achieved. A total of 82 steroidal saponins and nine flavonoids were identified or tentatively identified from T...
August 1, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28762049/biogenic-synthesis-of-gold-nanoparticles-from-terminalia-arjuna-bark-extract-assessment-of-safety-aspects-and-neuroprotective-potential-via-antioxidant-anticholinesterase-and-antiamyloidogenic-effects
#8
Natarajan Suganthy, Vijayan Sri Ramkumar, Arivalagan Pugazhendhi, Giovanni Benelli, Govindaraju Archunan
The development of neuroprotective drugs through eco-friendly production routes is a major challenge for current pharmacology. The present study was carried out to synthesize gold nanoparticles (AuNPs) through biogenic route using ethanolic bark extract of Terminalia arjuna, a plant of high interest in Asian traditional medicine, and to evaluate its neuroprotective effects. The synthesized AuNPs were characterized by UV-Vis spectroscopy, FTIR spectroscopy, XRD, FESEM, EDX, HRTEM, DLS, and zeta potential analyses...
July 31, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28761950/annals-graphic-medicine-american-doctors
#9
Kartik A Valluri
No abstract text is available yet for this article.
August 1, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28756735/ethical-issues-in-the-use-of-animal-models-for-tissue-engineering-reflections-on-legal-aspects-moral-theory-three-rs-strategies-and-harm-benefit-analysis
#10
Gabriel R Liguori, Bertus F Jeronimus, Tácia T de Aquinas Liguori, Luiz Felipe P Moreira, Martin C Harmsen
Animal experimentation requires a solid and rational moral foundation. Objective and emphatic decision-making and protocol evaluation by researchers and ethics committees remain a difficult and sensitive matter. This article presents three perspectives that facilitate a consideration of the minimally acceptable standard for animal experiments, in particular, in tissue engineering (TE) and regenerative medicine. First, we review the boundaries provided by law and public opinion in America and Europe. Second, we review contemporary moral theory to introduce the Neo-Rawlsian contractarian theory to objectively evaluate the ethics of animal experiments...
September 5, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28753264/lipidhunter-identifies-phospholipids-by-high-throughput-processing-of-lc-ms-and-shotgun-lipidomics-datasets
#11
Zhixu Ni, Georgia Angelidou, Mike Lange, Ralf Hoffmann, Maria Fedorova
Lipids are dynamic constituents of biological systems, rapidly responding to any changes in physiological conditions. Thus, there is a large interest in lipid-derived markers for diagnostic and prognostic applications, especially in translational and systems medicine research. As lipid identification remains a bottleneck of modern untargeted lipidomics, we developed LipidHunter, a new open source software for the high-throughput identification of phospholipids in data acquired by LC-MS and shotgun experiments...
September 5, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28740539/identifying-chinese-herbal-medicine-network-for-endometriosis-implications-from-a-population-based-database-in-taiwan
#12
Pei-Ju Tsai, Yi-Hsuan Lin, Jiun-Liang Chen, Sien-Hung Yang, Yu-Chun Chen, Hsing-Yu Chen
BACKGROUND: Endometriosis is a common but bothersome gynecological disease, and Chinese herbal medicine (CHM) is used for treating endometriosis. The aim of this study is to explore CHM network and core treatments for endometriosis by analyzing nationwide CHM prescription database. METHODS: From 1998 to 2013, the CHM prescriptions made primarily for endometriosis among women diagnosed with endometriosis (ICD-9-CM code: 671) by gynecologists during their reproductive age were collected...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28730309/a-simple-and-rapid-infrared-assisted-self-enzymolysis-extraction-method-for-total-flavonoid-aglycones-extraction-from-scutellariae-radix-and-mechanism-exploration
#13
Liping Wang, Haotian Duan, Jiebing Jiang, Jiakun Long, Yingjia Yu, Guiliang Chen, Gengli Duan
A new, simple, and fast infrared-assisted self enzymolysis extraction (IRASEE) approach for the extraction of total flavonoid aglycones (TFA) mainly including baicalein, wogonin, and oroxylin A from Scutellariae Radix is presented to enhance extraction yield. Extraction enzymolysis temperature, enzymolysis liquid-to-solid ratio, enzymolysis pH, enzymolysis time and infrared power, the factors affecting IRASEE procedure, were investigated in a newly designed, temperature-controlled infrared-assisted extraction (TC-IRAE) system to acquire the optimum analysis conditions...
July 20, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28725642/medicaid-adult-dental-benefit-impact-on-dental-utilization-a-university-clinic-setting
#14
Lynn Doan, Tamanna Tiwari, Diane Brunson, Clifton M Carey
INTRODUCTION: In 2014, the state of Colorado initiated new dental coverage benefits for adults in the Colorado Medicaid program. The goal of this study was to investigate the utilization and impact of this new dental coverage at the University of Colorado School of Dental Medicine. The utilization of dental services delivered and the numbers of patients in this program were compared before and after the implementation of the benefit. MATERIALS AND METHODS: This retrospective study compared the utilization of services provided 2 years prior and 2 years after the Medicaid adult benefit was made available...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28713914/systematic-identification-of-human-housekeeping-genes-possibly-useful-as-references-in-gene-expression-studies
#15
Maria Caracausi, Allison Piovesan, Francesca Antonaros, Pierluigi Strippoli, Lorenza Vitale, Maria Chiara Pelleri
The ideal reference, or control, gene for the study of gene expression in a given organism should be expressed at a medium‑high level for easy detection, should be expressed at a constant/stable level throughout different cell types and within the same cell type undergoing different treatments, and should maintain these features through as many different tissues of the organism. From a biological point of view, these theoretical requirements of an ideal reference gene appear to be best suited to housekeeping (HK) genes...
September 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28710713/a-consensus-for-the-development-of-a-vector-model-to-assess-clinical-complexity
#16
Gino Roberto Corazza, Catherine Klersy, Pietro Formagnana, Marco Vincenzo Lenti, Donatella Padula
The progressive rise in multimorbidity has made management of complex patients one of the most topical and challenging issues in medicine, both in clinical practice and for healthcare organizations. To make this easier, a score of clinical complexity (CC) would be useful. A vector model to evaluate biological and extra-biological (socio-economic, cultural, behavioural, environmental) domains of CC was proposed a few years ago. However, given that the variables that grade each domain had never been defined, this model has never been used in clinical practice...
July 14, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28682461/influence-of-decision-aids-on-oral-anticoagulant-prescribing-among-physicians-a-randomised-trial
#17
Cristian Baicus, Caterina Delcea, Alina Dima, Emilia Oprisan, Ciprian Jurcut, Gheorghe Andrei Dan
BACKGROUND: Oral anticoagulants (OAC) are underused in treatment of atrial fibrillation (AF), with differences in patient and physician preferences. For risk communication, the graphic showing risks on treatment contains all the information, therefore, the graphic showing risks without treatment may not be necessary. Here, our objective was to assess whether decision aids require information of risks without treatment and specifically whether presentation of 5-year stroke risk in patients with AF increases use of OACs compared with presentation of 1-year risk and whether decisions on treatment are different when physicians decide their own treatment vs...
July 6, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28681360/intact-protein-analysis-at-21-tesla-and-x-ray-crystallography-define-structural-differences-in-single-amino-acid-variants-of-human-mitochondrial-branched-chain-amino-acid-aminotransferase-2-bcat2
#18
Lissa C Anderson, Maria Håkansson, Björn Walse, Carol L Nilsson
Structural technologies are an essential component in the design of precision therapeutics. Precision medicine entails the development of therapeutics directed toward a designated target protein, with the goal to deliver the right drug to the right patient at the right time. In the field of oncology, protein structural variants are often associated with oncogenic potential. In a previous proteogenomic screen of patient-derived glioblastoma (GBM) tumor materials, we identified a sequence variant of human mitochondrial branched-chain amino acid aminotransferase 2 as a putative factor of resistance of GBM to standard-of-care-treatments...
July 5, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28672381/annals-graphic-medicine-july-plunge
#19
Michael Natter
No abstract text is available yet for this article.
July 4, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28672380/annals-graphic-medicine-internship
#20
Jason Bitterman
No abstract text is available yet for this article.
July 4, 2017: Annals of Internal Medicine
keyword
keyword
11429
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"