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https://www.readbyqxmd.com/read/27900970/clinical-features-and-histological-patterns-of-lupus-nephritis-in-a-single-center-of-south-india
#1
Clement Wilfred Devadass, Vijaya Viswanath Mysorekar, Mahesh Eshwarappa, Lakshminarayanan Mekala, M Gireesh Siddaiah, K Gurudev Channabasappa
Renal involvement occurs in up to 60% of patients with systemic lupus erythematosus (SLE) and signifies a poor prognosis. The class of lupus nephritis (LN), determined on renal biopsy evaluation, guides the therapeutic management and has prognostic connotations. Our aim is to determine the clinicolaboratory features and histopathological patterns of LN at presentation in our local (South Indian) population. The study was conducted in a tertiary care hospital in South India between 2009 and 2014 on SLE patients with clinical evidence of LN...
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27859683/s2k-guideline-for-treatment-of-cutaneous-lupus-erythematosus
#2
Annegret Kuhn, Elisabeth Aberer, Zsuzsanna Bata-Csörgő, Marzia Caproni, Andreas Dreher, Camille Frances, Regine Gläser, Hans-Wilhelm Klötgen, Aysche Landmann, Branka Marinovic, Filippa Nyberg, Rodica Olteanu, Annamari Ranki, Jacek C Szepietowski, Beatrix Volc-Platzer
Cutaneous lupus erythematosus (CLE) is a rare inflammatory autoimmune disease with heterogeneous subtypes. To date, no therapeutic agents have been licensed specifically for patients with this disease entity and topical and systemic drugs are mostly used "off-label". The aim of the present guideline was to achieve a broad consensus on treatment strategies for patients with CLE by a European subcommittee, guided by the European Dermatology Forum (EDF) and supported by the European Academy of Dermatology and Venereology (EADV)...
November 15, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27790692/shared-decision-making-and-patient-decision-aids-in-dermatology
#3
J Tan, E Linos, M A Sendelweck, E J van Zuuren, S Ersser, R P Dellavalle, H Williams
Shared decision making combines individual patient interests and values with clinical best evidence under the guiding principle of patient autonomy. Patient decision aids can support shared decision making and facilitate decisions that have multiple options with varying outcomes for which patients may attribute different values. Given the variable psychosocial impact of skin disease on individuals and relative uncertainty regarding best treatments and their adherence in many dermatological conditions, informed shared decision making, supported by patient decision aids, should constitute a central component of dermatological care...
November 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27785707/medical-malpractice-in-dermatology-part-ii-%C3%A2-what-to-do-once-you-have-been-served-with-a-lawsuit
#4
Vidhi V Shah, Marshall B Kapp, Stephen E Wolverton
Facing a malpractice lawsuit can be a daunting and traumatic experience for healthcare practitioners, with most clinicians naïve to the legal landscape. It is crucial for physicians to know and understand the malpractice system and his or her role once challenged with litigation. We present part II of a two-part series addressing the most common medicolegal questions that cause a great deal of anxiety. Part I focused upon risk-management strategies and prevention of malpractice lawsuits, whereas part II provides helpful suggestions and guidance for the physician who has been served with a lawsuit complaint...
December 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27768177/addressing-practice-gaps-in-cutaneous-surgery-advances-in-diagnosis-and-treatment
#5
Kathryn L Kreicher, Jeremy S Bordeaux
Importance: Cutaneous surgery is performed by otolaryngologists, plastic surgeons, oculoplastic surgeons, dermatologic surgeons, and some primary care physicians. Practice gaps exist among cutaneous surgeons, as do differences in how different physicians approach preoperative, intraoperative, and postoperative decision-making. Objective: To present the newest and best evidence to close common practice gaps in cutaneous surgery. Evidence Review: We performed a detailed search of peer-reviewed publications that were identified through a search of PubMed/MEDLINE (January 1, 2000, through June 30, 2016) using the literature search terms "cutaneous surgery," "Mohs micrographic surgery," "plastic surgery," in combination with "safety," "cost," "anesthesia," "anti-coagulation," "bleeding," "pain," "analgesia," "anxiety," or "infection," among others...
October 20, 2016: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27741336/bensal-hp-for-second-intention-healing-following-mohs-micrographic-surgery-or-shave-skin-biopsy-an-open-label-pilot-study
#6
Breanne Mordorski, Adam J Friedman, Leon H Kircik
Dermatologists frequently create cutaneous defects that heal by second intention, yet there is no universal protocol for wound care in this setting. Several ointments commonly used for wound healing are not cost effective as they contain known contact allergens, contribute to antimicrobial resistance, and do not enhance the healing process. Recent studies indicate that Bensal HP, a commercially available ointment used for a variety of dermatologic conditions, may be useful for wound healing; although clinical data is currently limited...
October 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/27690471/clinical-practice-guideline-for-diagnosis-and-management-of-urticaria
#7
Kanokvalai Kulthanan, Papapit Tuchinda, Leena Chularojanamontri, Pattriya Chanyachailert, Wiwat Korkij, Amornsri Chunharas, Siriwan Wananukul, Wanida Limpongsanurak, Suwat Benjaponpitak, Wanee Wisuthsarewong, Kobkul Aunhachoke, Vesarat Wessagowit, Pantipa Chatchatee, Penpun Wattanakrai, Orathai Jirapongsananuruk, Jettanong Klaewsongkram, Nopadon Noppakun, Pakit Vichyanond, Puan Suthipinittharm, Kiat Ruxrungtham, Srisupalak Singalavanija, Jarungchit Ngamphaiboon
Urticaria is a common skin condition that can compromise quality of life and may affect individual performance at work or school. Remission is common in majority of patients with acute spontaneous urticaria (ASU); however, in chronic cases, less than 50% had remission. Angioedema either alone or with urticaria is associated with a much lower remission rate. Proper investigation and treatment is thus required. This guideline, a joint development of the Dermatological Society of Thailand, the Allergy, Asthma, and Immunology Association of Thailand and the Pediatric Dermatological Society of Thailand, is graded and recommended based on published evidence and expert opinion...
September 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27623742/laser-thermal-therapy-monitoring-using-complex-differential-variance-in-optical-coherence-tomography
#8
William C Y Lo, Néstor Uribe-Patarroyo, Ahhyun S Nam, Martin Villiger, Benjamin J Vakoc, Brett E Bouma
Conventional thermal therapy monitoring techniques based on temperature are often invasive, limited by point sampling, and are indirect measures of tissue injury, while techniques such as magnetic resonance and ultrasound thermometry are limited by their spatial resolution.  The visualization of the thermal coagulation zone at high spatial resolution is particularly critical to the precise delivery of thermal energy to epithelial lesions. In this work, an integrated thulium laser thermal therapy monitoring system was developed based on complex differential variance (CDV), which enables the 2D visualization of the dynamics of the thermal coagulation process at high spatial and temporal resolution with an optical frequency domain imaging system...
September 14, 2016: Journal of Biophotonics
https://www.readbyqxmd.com/read/27612905/evaluation-of-hepatitis-b-vaccination-among-lichen-planus-patients
#9
K Balighi, M Daneshpazhooh, M Nasimi, S Loloee, A Asadi, A Azizpour
Lichen planus (LP) is an idiopathic chronic inflammatory mucocutaneous disease. Many reports in the literature have described hepatitis B vaccine as a predisposing factor for LP. This study was performed to determine the rate of previous vaccination against hepatitis B in LP patients. This was a cross sectional study on LP patients. Diagnosis of LP was confirmed by histological examination. Data were gathered by dermatology residents based on a checklist designed to guide their interview. Blood samples were tested for HBsAB titer, HBsAg, HCV Ab and liver function tests...
July 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27607323/the-clinical-spectrum-of-kaposiform-hemangioendothelioma-and-tufted-angioma
#10
Stacy E Croteau, Deepti Gupta
Kasposiform hemoangioendothelioma (KHE) and tufted angioma (TA) are classifed as vascular tumors with locally aggressive and benign growth potential, respectively, within the classification schema proposed by the International Society for the Study of Vascular Anomalies. A unique feature of these vascular tumors is the risk of Kasabach-Merritt phenomenon (KMP), a severe thrombocytopenia with mild to moderate coagulopathy resulting from intralesional platelet trapping. As with many vascular anomalies, accurate description of clinical course, responses to therapy, and long-term outcomes have been hindered by lesion misidentification, imprecise nomenclature, and lack of prospective, randomized clinical trials to assess therapeutic efficacy...
September 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27579792/european-consensus-based-s2k-guideline-on-the-management-of-herpes-zoster-guided-by-the-european-dermatology-forum-edf-in-cooperation-with-the-european-academy-of-dermatology-and-venereology-eadv-part-2-treatment
#11
R N Werner, A F Nikkels, B Marinović, M Schäfer, M Czarnecka-Operacz, A M Agius, Z Bata-Csörgő, J Breuer, G Girolomoni, G E Gross, S Langan, R Lapid-Gortzak, T H Lesser, U Pleyer, J Sellner, G M Verjans, P Wutzler, C Dressler, R Erdmann, S Rosumeck, A Nast
BACKGROUND: Herpes zoster (HZ, shingles) is a frequent medical condition which may severely impact the quality of life of affected patients. Different therapeutic approaches to treat acute HZ are available. OBJECTIVE: The aim of this European project was the elaboration of a consensus-based guideline on the management of patients who present with HZ, considering different patient populations and different localisations. This interdisciplinary guideline aims at an improvement of the outcomes of the acute HZ management concerning disease duration, acute pain and quality of life of the affected patients and at a reduction of the incidence of PHN and other complications...
August 31, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27536503/what-are-your-patients-reading-online-about-soft-tissue-fillers-an-analysis-of-internet-information
#12
Mona T Al-Taha, Sarah A Al Youha, Courtney E Bull, Michael B Butler, Jason G Williams
BACKGROUND: Soft-tissue fillers are increasingly being used for noninvasive facial rejuvenation. They generally offer minimal downtime and reliable results. However, significant complications are reported and patients need to be aware of these as part of informed consent. The Internet serves as a vital resource to inform patients of the risks and benefits of this procedure. METHODS: Three independent reviewers performed a structured analysis of 65 Websites providing information on soft-tissue fillers...
July 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27531645/koilonychia-an-update-on-pathophysiology-differential-diagnosis-and-clinical-relevance
#13
J Walker, R Baran, N Vélez, N Jellinek
Koilonychia, a concave nail dystrophy, has multiple aetiologies and may be hereditary, acquired or idiopathic. Within dermatology, koilonychia is often a manifestation of an inflammatory dermatosis such as psoriasis or lichen planus, or a sign of onychomycosis. Other disease associations include iron store abnormalities, Plummer-Vinson Syndrome, nutritional deficiencies and occupational or traumatic aetiologies. In young children, koilonychia of the toenails is commonly transient and idiopathic, although familial and syndromic cases are reported...
August 17, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27472234/practical-strategies-to-improve-the-clinical-utility-of-the-dermatopathology-report
#14
Martin J Trotter, Sheila Au, Karen A Naert
CONTEXT: -Dermatologists and subspecialty dermatopathologists, working together over many years, develop a common understanding of clinical information provided on the requisition and of terminology used in the pathology report. Challenges arise for pathologists without additional subspecialty training in dermatology/dermatopathology, and for any pathologist reporting skin biopsies for nondermatologists such as general practitioners or surgeons. OBJECTIVE: -To provide practical strategies to improve efficiency of dermatopathology sign-out, at the same time providing the clinician with clear diagnostic and prognostic information to guide patient management...
August 2016: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27424050/-differential-diagnosis-of-basal-cell-carcinoma-of-the-face-dermatologist-advice-may-avoid-surgery
#15
E Combes, J-M Foletti, J Villeret, L Guyot, P Berbis
INTRODUCTION: Basal cell carcinoma (BCC) is the most common skin cancer in France. It is commonly diagnosed in front of a papule or nodule of the face. The surgeon should be able to question the diagnosis of BCC when nodular lesions are untypical, keeping in mind that some differential diagnoses require only medical treatment. OBSERVATIONS: The authors successively describe three non infectious entities mimicking BCC of the face, requiring purely medical treatment: facial granuloma described by Lever, cutaneous pseudolymphoma, sarcoidosis...
July 13, 2016: Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale
https://www.readbyqxmd.com/read/27420914/splinter-hemorrhages-of-the-nails-a-systematic-review-of-clinical-features-and-associated-conditions
#16
Roger Haber, Rana Khoury, Elio Kechichian, Roland Tomb
Splinter hemorrhages (SHs) of the nails represent a frequent although not specific clinical finding that has been associated with conditions of varying severity. However, to date, there is no single report of their characteristics and etiologies. The aim of this study is to guide clinical practice by reviewing all of the data concerning SH of the nails that have become available since the first description of this condition was published in 1923, with particular reference to all clinical features, associated medical conditions, pathogenesis, and necessary workup...
July 15, 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27375320/irritant-dermatitis-to-staphylinid-beetle-in-indian-troops-in-congo
#17
B Vasudevan, D C Joshi
BACKGROUND: Contact dermatitis to Staphylinid beetle is a well known entity worldwide. Paederus sabaeus (Econda) species of this insect was responsible for a widespread occurrence of this dermatitis in United Nations (UN) troops posted in Congo. This study was undertaken to observe the various aspects of this unique dermatitis in the mission area. METHODS: All clinically diagnosed cases of contact dermatitis to Econda occurring in Indian troops posted to UN mission in Congo during the study period were included...
April 2010: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/27348356/topically-applied-lipid-and-surfactant-based-nanoparticles-in-the-treatment-of-skin-disorders
#18
Eline Desmet, Mireille Van Gele, Jo Lambert
INTRODUCTION: In the treatment of dermatological disorders, topical drug administration is a mainstay. However, nanoparticle-based carrier systems could improve and expand the current therapeutic range via localized delivery of active ingredients. AREAS COVERED: This review gives a detailed description of lipid- and surfactant-based drug delivery systems which have been explored for topical drug administration. To guide researchers in their choice of delivery system, an informative decision tree is included...
June 27, 2016: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/27348182/image-guided-automatic-triggering-of-a-fractional-co2-laser-in-aesthetic-procedures
#19
Sławomir Wilczyński, Robert Koprowski, Barbara K Wiernek, Barbara Błońska-Fajfrowska
BACKGROUND: Laser procedures in dermatology and aesthetic medicine are associated with the need for manual laser triggering. This leads to pulse overlapping and side effects. METHODS: Automatic laser triggering based on image analysis can provide a secure fit to each successive doses of radiation. A fractional CO2 laser was used in the study. 500 images of the human skin of healthy subjects were acquired. Automatic triggering was initiated by an application together with a camera which tracks and analyses the skin in visible light...
September 1, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27347633/assessing-surgical-training-and-deliberate-practice-methods-in-dermatology-residency-a-survey-of-dermatology-program-directors
#20
Julia Dai, Jeremy S Bordeaux, Christopher J Miller, Joseph F Sobanko
BACKGROUND: Resident surgical education and technical skills may be enhanced with deliberate practice-based learning. Deliberate practice methods, such as simulation-based training and formal skills-based assessments, allow for trainees to repeatedly practice a defined task with expert supervision and feedback. OBJECTIVE: The authors sought to characterize how surgical skills are taught and assessed in dermatology residency, with an emphasis on whether deliberate practice methods are incorporated in the surgical curriculum...
August 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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