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https://www.readbyqxmd.com/read/29747156/maternal-areola-ph-a-chemical-basis-for-mother-infant-recognition
#1
Vincenzo Zanardo, Francesca Volpe, Matteo Parotto, Lara Giliberti, Alphonse Simbi, Lorenzo Severino, Gianluca Straface
BACKGROUND: The human female's areolar region is the point of arrival of a natural progression from birth to breastfeeding continuum, supported by numerous functional features. AIMS: The aim of this study was to look more closely into the areola' skin chemical signals that are uniquely important for mother-infant chemoemission, chemoreception, and breastfeeding continuum. STUDY DESIGN: A dermatological study of the areolae and corresponding breast quadrants was undertaken on 71 healthy, at-term women...
May 7, 2018: Early Human Development
https://www.readbyqxmd.com/read/29716801/eruptive-xanthoma-in-the-setting-of-hypertriglyceridemia-and-pancreatitis
#2
Matthew Stark, Jonathan Stuart
BACKGROUND: Undifferentiated dermatologic complaints are often encountered in the emergency department. While a patient's exposures, risk factors, and comorbidities may help guide emergency department evaluation, the accurate diagnosis of dermatologic findings is critical to allowing rapid identification and treatment of disease. CASE: In this vignette we discuss a case of eruptive xanthoma in a 33-year-old male with diabetic ketoacidosis and pancreatitis. DISCUSSION: Dermatologic complaints pose a unique challenge to the emergency physician...
April 25, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29667792/habit-reversal-training-for-body-focused-repetitive-behaviors-a-practical-guide-for-the-dermatologist
#3
Amber B Dunbar, Michelle Magid, Jason S Reichenberg
Habit reversal training (HRT) is a clinically effective treatment for body-focused repetitive disorders (BFRDs) such as trichotillomania, onychophagia, and dermatillomania. Despite many dermatology providers knowing the term HRT, very few understand what HRT is and how it actually works. In this article, we give a detailed explanation of HRT and walk the reader through a six-session HRT protocol. We will briefly discuss adjunct interventions for BFRDs, including pharmacological approaches. We aim to make dermatologists more comfortable in offering basic HRT within their clinics and to close the gap that currently exists between patients who are HRT candidates and those who receive HRT treatment...
April 18, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29571521/outpatient-dermatological-diagnoses-in-spain-results-from-the-national-diaderm-random-sampling-project
#4
A Buendía-Eisman, S Arias-Santiago, A Molina-Leyva, Y Gilaberte, P Fernández-Crehuet, H Husein-ElAhmed, A Viera-Ramírez, P Fernández-Peñas, R Taberner, M Á Descalzo, I García-Doval
INTRODUCTION: Dermatologists perform most of their work in outpatient or private clinics. Data on the diagnoses made by dermatologists in these settings are lacking, however, as outpatient activity, unlike hospital activity, is difficult to code. The aim of this study was to analyze the diagnoses made by members of the Spanish Academy of Dermatology and Venereology (AEDV) at dermatology clinics in Spain. METHODODOLY: We selected a random sample of AEDV dermatologists drawn from the AEDV list and stratified by geographic area...
March 20, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29532244/toxican-a-guide-for-grading-dermatological-adverse-events-of-cancer-treatments
#5
L Peuvrel, J Cassecuel, C Bernier, G Quéreux, M Saint-Jean, M Le Moigne, C Frénard, A Khammari, B Dréno
PURPOSE: The dermatological toxicity of cancer treatments is frequent and sometimes debilitating. Its reference classification, the NCI-CTCAE (National Cancer Institute-Common Terminology Criteria for Adverse Events), is sometimes difficult to use and does not include yet the newest toxicities. Our objective was to create a guide, TOXICAN, based on the CTCAE, which is easy to use in everyday practice and which facilitates the recognition and grading of these dermatological toxicities...
March 12, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29502346/past-present-and-future-of-in-vitro-3d-reconstructed-inflammatory-skin-models-to-study-psoriasis
#6
REVIEW
Hanna Niehues, Ellen H van den Bogaard
Psoriasis is a common chronic inflammatory skin disease with a significant socio-economic impact that can greatly affect the patients' quality of life. The prevailing dogma in the aetiology and pathophysiology of this complex disease is that skin cells, immune cells and environmental factors contribute to psoriatic skin inflammation. For a better understanding of the disease pathogenesis, models are required that mimic the disease and which can be used to develop therapeutics. Over the last decades, in vitro human reconstructed skin models have been widely used in dermatological research and have also been developed to mimic psoriatic skin...
March 4, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29480875/evidence-supports-blind-screening-for-internal-malignancy-in-dermatomyositis-data-from-2-large-us-dermatology-cohorts
#7
MULTICENTER STUDY
Hayley Leatham, Courtney Schadt, Sarah Chisolm, Deborah Fretwell, Lorinda Chung, Jeffrey P Callen, David Fiorentino
The association between dermatomyositis and internal malignancy is well established, but there is little consensus about the methods of cancer screening that should be utilized.We wished to analyze the prevalence and yield of selected cancer screening modalities in patients with dermatomyositis.We performed a retrospective analysis of 2 large US dermatomyositis cohorts comprising 400 patients.We measured the frequency of selected screening tests used to search for malignancy. Patients with a biopsy-confirmed malignancy were identified...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29449018/-guide-to-university-hospital-careers-in-dermatology-the-grent-graines-engrais-tuteurs-seed-fertilizer-plant-stick-program
#8
C Gaudy-Marqueste, M Samimi, A Soria, S Aractingi, C Bodemer, O Chosidow, B Cribier, J P Lacour, C Paul, M A Richard, M Beylot-Barry, B Dreno
No abstract text is available yet for this article.
March 2018: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29429551/dermatology-and-immunoglobulin-therapy-who-to-treat-and-how-to-administer-immunoglobulins
#9
F J Navarro-Triviño, I Pérez-López, R Ruíz-Villaverde
Intravenous immunoglobulin (IVIG) replacement therapy has been used in immune deficiency diseases for more than 50 years. The indications for this treatment have evolved, however, and IVIG therapy is now used in various diseases in which the immune system plays a prominent role. IVIG therapy has carved out a niche in dermatology for the treatment of such conditions as dermatomyositis, autoimmune bullous diseases, and toxic epidermal necrolysis. Special attention has been paid to this therapy in recent years...
February 8, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29406058/cutaneous-lesions-of-the-external-genitalia
#10
REVIEW
Emily Yura, Sarah Flury
Individuals with cutaneous diseases of the external genitalia often initially present to their primary care provider. When present, these conditions may be associated with considerable physical symptoms and psychological distress. Dermatoses affecting the genitals may be of infectious, inflammatory, or neoplastic cause, and can be processes confined to the genitalia or a manifestation of a more widespread dermatologic condition. This article provides a guide to recognizing and managing common genital dermatoses and when to refer for specialist opinion...
March 2018: Medical Clinics of North America
https://www.readbyqxmd.com/read/29399266/a-retrospective-analysis-of-surveillance-adherence-of-patients-after-treatment-of-primary-cutaneous-melanoma
#11
Jeave Reserva, Monica Janeczek, Cara Joyce, Amanda Goslawski, Hwala Hong, Feng-Ning Yuan, Neelam Balasubramanian, Laura Winterfield, James Swan, Rebecca Tung
BACKGROUND: Melanoma surveillance serves to identify new primary melanomas and curable locoregional or early distant recurrences. Although an optimal melanoma surveillance strategy has not been determined, several clinical guidelines exist. OBJECTIVE: The aim of this study was to identify demographic and clinico-pathologic variables associated with poor adherence to National Comprehensive Cancer Network (NCCN) melanoma surveillance guidelines. DESIGN: We retrospectively reviewed the initial five-year dermatology follow-up visit frequencies of melanoma patients and extracted basic demographic and clinical data from their medical records...
December 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/29389330/research-techniques-made-simple-pharmacoepidemiology-research-methods-in-dermatology
#12
Megan H Noe, Joel M Gelfand
Clinical trials have several important limitations for evaluating the safety of new medications, leading to many adverse events not being identified until the postmarketing period. Descriptive studies, including case reports, case series, cross-sectional, and ecologic studies, help identify potential safety signals and generate hypotheses. Further research using analytic study methods, including case-control studies and cohort studies, are necessary to determine if an association truly exists and to better understand the potential for causation...
February 2018: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29371535/molecular-identification-and-antifungal-susceptibility-patterns-of-clinical-dermatophytes-following-clsi-and-eucast-guidelines
#13
Yubhisha Dabas, Immaculata Xess, Gagandeep Singh, Mragnayani Pandey, Suneeta Meena
Dermatophytes are associated with superficial infections in humans worldwide. The aim of the present study was to determine the species distribution and susceptibility patterns of clinical dermatophytes. Samples received for routine mycological processing from 124 suspected cases attending a dermatologic clinic in a tertiary care hospital were included in the study. On direct microscopy, 74.1% (92/124) were positive and 53.2% (66/124) grew on culture. The isolates were comprised of Trichophyton interdigitale (56%) followed by Trichophyton tonsurans (25...
March 23, 2017: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29362629/primary-solitary-melanoma-of-the-lymphatic-nodes-or-a-single-metastasis-of-unknown-melanoma-do-we-need-a-new-staging-system
#14
Georgi Tchernev, Anastasiya Chokoeva, Lyubomira Victor Popova
BACKGROUND: Malignant melanoma is a disease which has a cutaneous origin in 90% of the patients, but in rare cases, it could be discovered as secondary deposits with unknown primary site. Metastatic Malignant Melanoma occurs without a primary site in about 3% of all melanoma patients, and it could be divided into two main groups: metastatic lymph nodes' involvement or non-lymph nodes disease. The lack of unified classification and staging system, provided by AJCC (2009), as well as the lack for curtain diagnostic and therapeutic protocol, prompt us to raise the question what is the right way to precede in cases of metastasis of the lymph nodes, without evidence of a primary tumour? CASE REPORT: We report a case of 67-years- old woman who presented in the dermatology clinic after a surgical removal of an enlarged lymph node in her left femoral area, verified histologically as a metastasis of melanoma...
December 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29351371/implementation-of-standardized-clinical-processes-for-tpmt-testing-in-a-diverse-multidisciplinary-population-challenges-and-lessons-learned
#15
Kristin W Weitzel, D Max Smith, Amanda R Elsey, Benjamin Q Duong, Benjamin Burkley, Michael Clare-Salzler, Yan Gong, Tara A Higgins, Benjamin Kong, Taimour Langaee, Caitrin W McDonough, Benjamin J Staley, Teresa T Vo, Dyson T Wake, Larisa H Cavallari, Julie A Johnson
Although thiopurine S-methyltransferase (TPMT) genotyping to guide thiopurine dosing is common in the pediatric cancer population, limited data exist on TPMT testing implementation in diverse, multidisciplinary settings. We established TPMT testing (genotype and enzyme) with clinical decision support, provider/patient education, and pharmacist consultations in a tertiary medical center and collected data over 3 years. During this time, 834 patients underwent 873 TPMT tests (147 (17%) genotype, 726 (83%) enzyme)...
March 2018: Clinical and Translational Science
https://www.readbyqxmd.com/read/29331035/noninvasive-optical-spectroscopy-for-identification-of-non-melanoma-skin-cancer-pilot-study
#16
David J Carpenter, Mirabelle B Sajisevi, Nikita Chapurin, Clifford Scott Brown, Tracy Cheng, Gregory M Palmer, Daniel S Stevenson, Caroline L Rao, Russell P Hall, Charles R Woodard
OBJECTIVE: Optical spectroscopy offers a noninvasive alternative to biopsy as a first-line screening tool for suspicious skin lesions. This study sought to define several optical parameters across malignant and benign tissue types. STUDY DESIGN: Prospective pilot trial utilizing the Zenalux IM1 optical spectroscopy device from April 2016 to February 2017. For each skin lesion, provider pre-biopsy probability of malignancy was compared to histolopathologic diagnosis...
March 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29231446/-the-indications-of-acupuncture-moxibustion-in-china-state-compiled-textbooks
#17
Weijuan Gang, Xiaodong Wu, Fang Wang, Xin Wang
The Acupuncture-moxibustion and Acupuncture-moxibustion therapy have been the state-compiled textbooks of acupuncture-moxibustion in colleges and universities of TCM for nearly more than half a century, which play a regulating and guiding role for acupuncture education and to a certain extent represent the development status of this discipline. The indications included in Acupuncture-moxibustion from 1th edition to 7th edition and Acupuncture-moxibustion therapy from 1th edition to 3rd edition were analyzed in this study, which was aimed to basically reflect the current situation of acupuncture indications...
March 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29202605/toxic-epidermal-necrolysis-spectrum-management-at-sunnybrook-health-sciences-centre-our-multidisciplinary-approach-after-review-of-the-current-evidence
#18
Alexandra Mereniuk, Alejandra Jaque, Marc G Jeschke, Neil H Shear
Toxic epidermal necrolysis spectrum (TENS) is a rare yet severe adverse drug reaction associated with a high mortality rate. Beyond supportive care, there is still no established therapy for TENS, although recent meta-analyses and UK guideline recommendations have attempted to offer a review of relevant literature on this difficult topic. As most directed treatments lack clear consensual evidence, care centres often resort to establishing their own strategies. As Canada's largest adult burn centre and the provincial reference centre for most burn patients in Ontario, our team at the Ross Tilley Burn Centre, in collaboration with the Department of Dermatology at Sunnybrook Health Sciences Centre, Toronto, Canada, has managed over 60 confirmed cases of TENS over the past 2 decades...
March 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29197467/diagnostic-tools-to-use-when-we-suspect-an-allergic-reaction-to-a-tattoo-a-proposal-based-on-cases-at-our-hospital
#19
I González-Villanueva, J F Silvestre Salvador
INTRODUCTION: Tattooing has become a popular practice in western countries, particularly among younger populations. Tattoos, however, can cause complications, such as infections, allergic or foreign-body reactions, and even systemic inflammatory responses. PATIENTS AND METHODS: We conducted a retrospective study of all patients seen for tattoo-related complications at our skin allergy unit between January 2002 and December 2016. RESULTS: We studied 23 patients...
March 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29186267/incidence-of-skin-diseases-diagnosed-in-a-public-institution-comparison-between-2003-and-2014
#20
COMPARATIVE STUDY
Livia Maria Zanardi Miguel, Marilia Formentini Scotton Jorge, Bruna Rocha, Hélio Amante Miot
Epidemiology of diseases is influenced by population socio-demographic circumstances. Therefore it can be modified along the time. There are no studies exploring epidemiological transition in dermatology. This study investigated the incidence of dermatoses in new patients from a Brazilian country town public service in 2003 and 2014. There was a significant increase in the incidence of sexually transmitted diseases, leprosy, melasma, pruritus and hidradenitis suppurativa. However, a prominent reduction in scheduling of appointments for surgeries of benign lesions, drug reactions, urticaria and superficial mycoses was detected...
May 2017: Anais Brasileiros de Dermatologia
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