Alexander Hof, Henning Guthoff, Maysam Ahdab, Max Landerer, Jasper Schäkel, Jana Niehues, Maximilian Schorscher, Oscar Zimmermann, Holger Winkels, Philipp von Stein, Simon Geißen, Stephan Baldus, Matti Adam, Martin Mollenhauer, Dennis Mehrkens
Vascular diseases like atherosclerosis and abdominal aortic aneurysm (AAA) are common pathologies in the western world, promoting various potentially fatal conditions. Here, we evaluate high-resolution (HR) ultrasound in mouse models of atherosclerosis and AAA as a useful tool for noninvasive monitoring of early vascular changes in vivo. We used Apolipoprotein E-deficient ( ApoE -/- ) mice as an atherosclerosis model and induced AAA development by the implementation of Angiotensin II-releasing osmotic minipumps...
October 17, 2023: International Journal of Molecular Sciences