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aortic distensibility

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https://www.readbyqxmd.com/read/28210489/arterial-ventricular-coupling-and-parameters-of-vascular-stiffness-in-hypertensive-patients-role-of-gender
#1
Luca Faconti, Rosa Maria Bruno, Simona Buralli, Marta Barzacchi, Elisa Dal Canto, Lorenzo Ghiadoni, Stefano Taddei
OBJECTIVE: Non-invasive estimation of arterial-ventricular coupling has been extensively used for the evaluation of cardiovascular performance, however, a relative small amount of data is available regarding arterial-ventricular coupling and its components in hypertension. The present study was designed to investigate the relationship between left ventricular elastance, arterial elastance, parameters of vascular stiffness and the influence of gender in a population of hypertensive individuals...
January 2017: JRSM Cardiovascular Disease
https://www.readbyqxmd.com/read/28196483/aortic-stiffening-precedes-onset-of-heart-failure-with-preserved-ejection-fraction-in-patients-with-asymptomatic-diastolic-dysfunction
#2
Ilya Karagodin, Omer Aba-Omer, Rodney Sparapani, Jennifer L Strande
BACKGROUND: Identifying which patients with diastolic dysfunction will progress to heart failure with preserved ejection fraction (HFpEF) remains challenging. The goal of this study is to determine whether increased vascular stiffness as identified on 2D transthoracic echocardiography (TTE) serves as a biomarker for the development of HFpEF in patients with diastolic dysfunction. METHODS: The study design is a matched retrospective case-control study. Subjects with diastolic dysfunction were divided into two groups based on whether they had a clinical diagnosis of HFpEF...
February 14, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28193613/apparent-aortic-stiffness-in-children-with-pulmonary-arterial-hypertension-existence-of-vascular-interdependency
#3
Michal Schäfer, D Dunbar Ivy, Steven H Abman, Alex J Barker, Lorna P Browne, Brian Fonseca, Vitaly Kheyfets, Kendall S Hunter, Uyen Truong
BACKGROUND: Left ventricular dysfunction, mediated by ventricular interdependence, has been associated with negative outcomes in children with pulmonary arterial hypertension (PAH). Considering the dilation of the pulmonary arteries as a paramount sign of PAH, we hypothesized that the ascending aorta will present signs of apparent stiffness in children with PAH and that this effect may be because of mechanical interaction with the dilated main pulmonary artery (MPA). METHODS AND RESULTS: Forty-two children with PAH and 26 age- and size-matched controls underwent comprehensive cardiac magnetic resonance evaluation...
February 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28133167/-a-case-of-t1a-early-gastric-cancer-that-metastasized-to-the-right-femoral-muscles-six-years-and-seven-months-after-radical-surgery
#4
Chikara Ebisui, Rie Hamano, Yoichiro Nushijima, Tetsu Yanagisawa, Shu Okamura, Nariaki Fukuchi, Kohei Murata, Hideoki Yokouchi, Masakatsu Kinuta, Kazuhito Ohishi
A 49-year-old woman presented to our hospital complaining of abdominal distension and right thigh edema 6 years and 7 months after undergoing total gastrectomy for early gastric cancer in December 2008. The histopathological type of the tumor was poorly differentiated adenocarcinoma. The pathological findings led to a diagnosis of T1aN2M0, Stage II A disease. In August 2015, abdominal CT and MRI revealed para-aortic lymph node swelling, ascites, and a tumor on the right femoral muscles. We performed a needle biopsy of the femoral muscle, and the final diagnosis was intramuscular metastasis from the primary gastric cancer...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28116919/morning-blood-pressure-surge-and-arterial-stiffness-in-newly-diagnosed-hypertensive-patients
#5
Ali Kıvrak, Süleyman Özbiçer, Gülhan Yüksel Kalkan, Mustafa Gür
OBJECTIVE: We aimed to investigate the relationship between the morning blood pressure (BP) surge and arterial stiffness in patients with newly diagnosed hypertension. SUBJECTS AND METHODS: Three hundred and twenty four (mean age 51.7 ± 11.4 years) patients who had newly diagnosed hypertension with 24 h ambulatory BP monitoring were enrolled. Parameters of arterial stiffness, pulse wave velocity and augmentation index (Aix) were measured by applanation tonometry and aortic distensibility was calculated by echocardiography...
January 24, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28115806/a-novel-marker-of-impaired-aortic-elasticity-in-never-treated-hypertensive-patients-monocyte-high-density-lipoprotein-cholesterol-ratio
#6
Kadriye Gayretli Yayla, Uğur Canpolat, Çagri Yayla, Mehmet Kadri Akboğa, Ahmet Akyel, Ahmet Akdi, Gökhan Çiçek, Firat Ozcan, Osman Turak, Sinan Aydoğdu
BACKGROUND: Monocyte to high density lipoprotein cholesterol ratio (MHR) is generally understood to be a candidate marker of inflammation and oxidative stress. Therefore, we aimed to assess the association between MHR and aortic elastic properties in hypertensive patients. METHODS: A total of 114 newly-diagnosed untreated patients with hypertension and 71 healthy subjects were enrolled. Aortic stiffness index, aortic strain and aortic distensibility were measured by using echocardiography...
January 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/28114900/the-reverse-remodeling-of-the-aorta-in-patients-after-renal-transplantation-the-value-of-aortic-stiffness-index-prospective-echocardiographic-study
#7
Tomasz Zapolski, Jacek Furmaga, Andrzej Jaroszyński, Anna Wysocka, Sławomir Rudzki, Andrzej P Wysokiński
BACKGROUND: Atherosclerosis is regarded as a combination of two major separate diseases: atherosis and sclerosis. Sclerotic component depends on deterioration of elastic properties of the aortic wall and is called aortic stiffness. The most valuable, non-invasive method of aortic stiffness assessment is echocardiography, which allows to calculate the aortic stiffness index (ASI). ASI is an independent predictor of all-cause and cardiovascular mortality in different groups of patients...
January 23, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28102614/expression-of-cd4-cd28-null-t-lymphocytes-in-children-and-adolescents-with-type-1-diabetes-mellitus-relation-to-microvascular-complications-aortic-elastic-properties-and-carotid-intima-media-thickness
#8
Mona H El-Samahy, Azza A G Tantawy, Amira A M Adly, Nevin M Habeeb, Eman A R Ismail, Gehan M Hamed, Rasha Eladawy
BACKGROUND: Cardiovascular risk in type 1 diabetes mellitus (T1DM) is associated with endothelial dysfunction, inflammation, and altered immunity. CD4(+) CD28(null) T-cells are a subset of long-lived cytotoxic CD4(+) T-lymphocytes with proatherogenic and plaque-destabilizing properties. We hypothesized that the frequency of CD4(+) CD28(null) T-cells may be altered in T1DM and related to vascular complications. AIM: To assess the percentage of CD4(+) CD28(null) T-lymphocytes in children and adolescents with T1DM and their relation to vascular structure and glycemic control...
January 19, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28086801/two-dimensional-speckle-tracking-echocardiography-for-evaluation-of-dilative-ascending-aorta-biomechanics
#9
Monika Bieseviciene, Jolanta Justina Vaskelyte, Vaida Mizariene, Rasa Karaliute, Vaiva Lesauskaite, Raimonda Verseckaite
BACKGROUND: Two-dimensional (2D) echocardiography is one of the most feasible, noninvasive methods for assessing the aortic diameter and biomechanical changes. We studied possible interfaces between noninvasive biomechanical and speckle-tracking (ST) echocardiographic data from dilated aortas. METHODS: Altogether, 44 patients with dilative pathology of ascending aorta (DPAA) were compared with subjects without ascending aortic dilation (diameter <40 mm). DPAA patients formed two groups based on diameter size: group 1, ≤45 mm diameter; group 2, >45 mm...
January 13, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28045414/evaluation-of-left-atrial-mechanical-function-and-atrial-conduction-abnormalities-in-patients-with-isolated-bicuspid-aortic-valve
#10
Arif Arısoy, Kadriye Memiç, Selami Demirelli, Kayıhan Karaman, Fatih Altunkaş, Metin Karayakalı, Yusuf Karavelioğlu, Ataç Çelik
OBJECTIVE: Present study is an evaluation of left atrial (LA) mechanical and conduction function in patients with bicuspid aortic valve (BAV) without significant valve dysfunction, and an investigation of relationship between LA function and aortic elasticity. METHODS: Study population consisted of 34 isolated BAV patients (mean age: 34±13 years) and 29 healthy, age- and sex-matched volunteers (mean age: 30±10 years). LA volume was measured using biplane area-length method and LA active and passive emptying volume and fraction was calculated...
December 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28029670/evaluation-of-distensibility-and-stiffness-of-ascending-aortic-aneurysm-using-magnetic-resonance-imaging
#11
K K Tiwari, S Bevilacqua, G Aquaro, P Festa, L Ait-Ali, M Solinas
INTRODUCTION: Magnetic resonance imaging emerging as a new tool for the diagnosis and evaluation of ascending aortic aneurysm. The aim of our study is to evaluate in vivo distensibility and pulse wave velocity of the aortic wall using functional magnetic resonance imaging technique. METHODS: We enrolled 25 patients undergoing surgery for ascending aortic aneurysm and or aortic valve replacement for a period of 8 months. Preoperatively, all the patients underwent functional MRI study of the aorta...
October 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/28027889/extensibility-and-distensibility-of-the-thoracic-aorta-in-patients-with-aneurysm
#12
H W L de Beaufort, F J H Nauta, M Conti, E Cellitti, C Trentin, E Faggiano, G H W van Bogerijen, C A Figueroa, F L Moll, J A van Herwaarden, F Auricchio, S Trimarchi
OBJECTIVES: Reference values of aortic deformation during the cardiac cycle can be valuable for the pre-operative planning of thoracic endovascular aortic repair (TEVAR) and for facilitating computational fluid dynamics. This study aimed to quantify normal aortic extensibility (longitudinal extension) and distensibility (radial expansion), as well as pulsatile strain, in a group of 10 (>60 years) individuals with abdominal or thoracic aortic aneurysms. METHODS: ECG gated CT images of the thoracic aorta were reconstructed into virtual 3D models of aortic geometry...
February 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28005132/biomechanical-phenotyping-of-the-murine-aorta-what-is-the-best-control
#13
Chiara Bellini, Alexander/W Caulk, Guangxin Li, George Tellides, Jay Humphrey
The availability of diverse mouse models is revealing increasingly greater information on arterial mechanics, including homeostatic adaptations and pathologic maladaptations to genetic, pharmacological, and surgical manipulations. Fundamental to understanding such biomechanical changes, however, is reliable information on appropriate control vessels. In this paper, we contrast 15 different geometrical and mechanical metrics of biaxial ascending aortic mechanics across 7 different types of possible control mice...
December 22, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27964736/feasibility-of-cardiovascular-magnetic-resonance-derived-coronary-wave-intensity-analysis
#14
Claire E Raphael, Jennifer Keegan, Kim H Parker, Robin Simpson, Julian Collinson, Vass Vassiliou, Ricardo Wage, Peter Drivas, Stephen Strain, Robert Cooper, Ranil de Silva, Rod H Stables, Carlo Di Mario, Michael Frenneaux, Dudley J Pennell, Justin E Davies, Alun D Hughes, David Firmin, Sanjay K Prasad
BACKGROUND: Wave intensity analysis (WIA) of the coronary arteries allows description of the predominant mechanisms influencing coronary flow over the cardiac cycle. The data are traditionally derived from pressure and velocity changes measured invasively in the coronary artery. Cardiovascular magnetic resonance (CMR) allows measurement of coronary velocities using phase velocity mapping and derivation of central aortic pressure from aortic distension. We assessed the feasibility of WIA of the coronary arteries using CMR and compared this to invasive data...
December 9, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27934625/ultrasonographic-findings-in-two-sheep-with-enzootic-calcinosis
#15
U Braun, K Mitchell, S Schramm, S Nogler, J Hatt, A Malbon
This report describes 2 sheep with enzootic calcinosis characterized by abnormal cardiovascular and respiratory findings and ascites causing abdominal distension. Both sheep were anorexic and listless and had increased heart and respiratory rates. Auscultation of the heart revealed a gallop rhythm in sheep 1 and a loud systolic heart murmur in sheep 2. The activities of liver enzymes were severely increased in both sheep. Abdominal ultrasonography showed severe ascites and congestion of the liver and caudal vena cava...
December 2016: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/27928151/evaluation-of-arterial-stiffness-and-cardiac-function-in-patients-with-vascular-erectile-dysfunction-acute-effects-of-phosphodiesterase-5-inhibitor-tadalafil
#16
O Özdabakoğlu, S Güllülü, S Sağ, T Şentürk, H Kiliçarslan, A Tütüncü, M Keçebaş, I Baran, A Aydinlar
This study aimed to detect endothelial dysfunction in erectile dysfunction (ED) patients free from cardiovascular diseases or atherosclerotic risk factors and to evaluate acute effects of phosphodiesterase-5 inhibitor tadalafil on endothelial dysfunction and cardiac function. Thirty ED patients and 20 healthy male subjects (mean ages: 48.7±11.7 and 48.3±8.7 years, respectively) were enrolled. Endothelium functions were assessed by applanation tonometry. Aortic stiffness and cardiac function were evaluated by transthoracic echocardiography...
December 8, 2016: International Journal of Impotence Research
https://www.readbyqxmd.com/read/27923782/comparing-arterial-function-parameters-for-the-prediction-of-coronary-heart-disease-events-the-multi-ethnic-study-of-atherosclerosis-mesa
#17
Elizabeth K Hom, Daniel A Duprez, David R Jacobs, David A Bluemke, Lyndia C Brumback, Joseph F Polak, Carmen A Peralta, Philip Greenland, Sheryl L Magzamen, João A C Lima, Alban Redheuil, David M Herrington, James H Stein, Dhananjay Vaidya, Pamela Ouyang, Joel D Kaufman
Arterial dysfunction has been linked to decline in cardiac function and increased risk of cardiovascular disease events. We calculated the value of arterial function, measured at baseline (2000-2002), in predicting time to first coronary heart disease (CHD) event (median follow-up, 10.2 years) among participants in the Multi-Ethnic Study of Atherosclerosis (MESA). Measures included the following: C1 and C2, derived from diastolic pulse contour analysis from the radial artery blood pressure waveform obtained by tonometry (n = 6,336); carotid distensibility and Young's elastic modulus at the carotid artery, derived from carotid artery ultrasonography (n = 6,531 and 6,528); and aortic distensibility, measured using cardiac magnetic resonance imaging (n = 3,677)...
December 15, 2016: American Journal of Epidemiology
https://www.readbyqxmd.com/read/27905124/assessment-of-early-atherosclerosis-and-left-ventricular-dysfunction-in-children-with-21-hydroxylase-deficiency
#18
Rahmi Özdemir, Hüseyin Anil Korkmaz, Mehmet Küçük, Cem Karadeniz, Timur Meşe, Behzat Özkan
AIM: We analysed 25 children with 21-hydroxylase deficiency who received glucocorticoid and/or mineralocorticoid treatment for at least 12 months to determine the effects of the disease and its treatment on vascular structures and ventricular function. METHODS: Twenty-five patients with 21-hydroxylase-deficient congenital adrenal hyperplasia (CAH) and 25 control subjects were enrolled into this observational, cross-sectional study. The patients were investigated in terms of fasting blood glucose and insulin; fasting serum lipid profile; serum 17-hydroxyprogesterone; dehydroepiandrosterone sulphate; androstenedione; and adrenocorticotropic hormone...
November 7, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27884238/the-pressure-of-aging
#19
REVIEW
Majd AlGhatrif, Mingyi Wang, Olga V Fedorova, Alexei Y Bagrov, Edward G Lakatta
Significant hemodynamic changes ensue with aging, leading to an ever-growing epidemic of hypertension. Alterations in central arterial properties play a major role in these hemodynamic changes. These alterations are characterized by an initial decline in aortic distensibility and an increase of diastolic blood pressure, followed by a sharp increase in pulse wave velocity (PWV), and an increase in pulse pressure (PP) beyond the sixth decade. However, the trajectories of PWV and PP diverge with advancing age...
January 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/27856475/assessment-of-cardiovascular-remodelling-following-endovascular-aortic-repair-through-imaging-and-computation-the-core-prospective-observational-cohort-study-protocol
#20
Foeke J H Nauta, Arnoud V Kamman, El-Sayed H Ibrahim, Prachi P Agarwal, Bo Yang, Karen Kim, David M Williams, Joost A van Herwaarden, Frans L Moll, Kim A Eagle, Santi Trimarchi, Himanshu J Patel, C Alberto Figueroa
INTRODUCTION: Thoracic aortic stent grafts are orders of magnitude stiffer than the native aorta. These devices have been associated with acute hypertension, elevated pulse pressure, cardiac remodelling and reduced coronary perfusion. However, a systematic assessment of such cardiovascular effects of thoracic endovascular aortic repair (TEVAR) is missing. The CardiOvascular Remodelling following Endovascular aortic repair (CORE) study aims to (1) quantify cardiovascular remodelling following TEVAR and compare echocardiography against MRI, the reference method; (2) validate computational modelling of cardiovascular haemodynamics following TEVAR using clinical measurements, and virtually assess the impact of more compliant stent grafts on cardiovascular haemodynamics; and (3) investigate diagnostic accuracy of ECG and serum biomarkers for cardiac remodelling compared to MRI...
November 17, 2016: BMJ Open
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