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nano pillar

Frances J Harding, Salvatore Surdo, Bahman Delalat, Chiara Cozzi, Roey Elnathan, Stan Gronthos, Nicolas H Voelcker, Giuseppe Barillaro
Ordered arrays of silicon nano- to microscale pillars are used to enable biomolecular trafficking into primary human cells, consistently demonstrating high transfection efficiency can be achieved with broader and taller pillars that reported to date. Cell morphology on the pillar arrays is often strikingly elongated. Investigation of the cellular interaction with the pillar reveals that cells are suspended on pillar tips and do not interact with the substrate between the pillars. While cells remain suspended on pillar tips, acute local deformation of the cell membrane was noted, allowing pillar tips to penetrate the cell interior, while retaining cell viability...
October 17, 2016: ACS Applied Materials & Interfaces
Zhenggang Zhang, Xiaoyue Xu, Shuwei Wang, Zhe Peng, Meng Liu, Jingjing Zhou, Cai Shen, Deyu Wang
A nanostructured protective structure, pillared by the copper nanoclusters and in situ filled with lithium oxide in the interspace, is constructed to efficiently improve the cyclic stability and lifetime of lithium metal electrodes. The porous structure of copper nanoclusters enables high specific surface area, locally reduced current density, and dendrite suppressing, while the filled lithium oxide leads to the structural stability and largely extends the electrode lifespan. As a result of the synergetic protection of the proposed structure, lithium metal could be fully discharged with efficiency ∼97% for more than 150 cycles in corrosive alkyl carbonate electrolytes, without dendrite formation...
October 12, 2016: ACS Applied Materials & Interfaces
Zeinab Jahed, Ramin Zareian, Yeung Yeung Chau, Brandon B Seo, Mary West, Ting Y Tsui, Weijia Wen, Mohammad R K Mofrad
Three-dimensional vertically aligned nano- and micropillars have emerged as promising tools for a variety of biological applications. Despite their increasing usage, the interaction mechanisms of cells with these rigid structures and their effect on single- and collective-cell behaviors are not well understood for different cell types. In the present study, we examine the response of glioma cells to micropillar arrays using a new microfabricated platform consisting of rigid silicon micropillar arrays of various shapes, sizes, and configurations fabricated on a single platform...
September 14, 2016: ACS Applied Materials & Interfaces
Benjamin H Wunsch, Joshua T Smith, Stacey M Gifford, Chao Wang, Markus Brink, Robert L Bruce, Robert H Austin, Gustavo Stolovitzky, Yann Astier
Deterministic lateral displacement (DLD) pillar arrays are an efficient technology to sort, separate and enrich micrometre-scale particles, which include parasites, bacteria, blood cells and circulating tumour cells in blood. However, this technology has not been translated to the true nanoscale, where it could function on biocolloids, such as exosomes. Exosomes, a key target of 'liquid biopsies', are secreted by cells and contain nucleic acid and protein information about their originating tissue. One challenge in the study of exosome biology is to sort exosomes by size and surface markers...
August 1, 2016: Nature Nanotechnology
Dinesh Kumar, K Konishi, Nikhil Kumar, S Miwa, A Fukushima, K Yakushiji, S Yuasa, H Kubota, C V Tomy, A Prabhakar, Y Suzuki, A Tulapurkar
The transfer of spin angular momentum to a nanomagnet from a spin polarized current provides an efficient means of controlling the magnetization direction in nanomagnets. A unique consequence of this spin torque is that the spontaneous oscillations of the magnetization can be induced by applying a combination of a dc bias current and a magnetic field. Here we experimentally demonstrate a different effect, which can drive a nanomagnet into spontaneous oscillations without any need of spin torque. For the demonstration of this effect, we use a nano-pillar of magnetic tunnel junction (MTJ) powered by a dc current and connected to a coplanar waveguide (CPW) lying above the free layer of the MTJ...
2016: Scientific Reports
Shuguang Wang, Tong Zhou, Dehui Li, Zhenyang Zhong
The scalable array of ordered nano-pillars with precisely controllable quantum nanostructures (QNs) are ideal candidates for the exploration of the fundamental features of cavity quantum electrodynamics. It also has a great potential in the applications of innovative nano-optoelectronic devices for the future quantum communication and integrated photon circuits. Here, we present a synthesis of such hybrid system in combination of the nanosphere lithography and the self-assembly during heteroepitaxy. The precise positioning and controllable evolution of self-assembled Ge QNs, including quantum dot necklace(QDN), QD molecule(QDM) and quantum ring(QR), on Si nano-pillars are readily achieved...
2016: Scientific Reports
Hadi Nazaripoor, Charles R Koch, Mohtada Sadrzadeh, Subir Bhattacharjee
To improve the electrically assisted patterning process and create smaller sized features with the higher active surface area, the combined thermocapillary-electrohydrodynamic (TC-EHD) instability of liquid nanofilms is considered. First, the 3-D thin film equation is rederived for nonisothermal films and then the influential factors on the dynamics and stability of thin liquid film are found using linear stability (LS) analysis. Nonlinear studies are also conducted to investigate the long-time evolution of the interface using an in-house developed Fortran code employing high order finite difference and adaptive time step solver for the spatial and time derivatives...
June 14, 2016: Langmuir: the ACS Journal of Surfaces and Colloids
Xin Yan, Pradeep Sharma
Conventional molecular dynamics simulations enable the elucidation of an astonishing array of phenomena inherent in the mechanical and chemical behavior of materials. Unfortunately, current computational limitations preclude accounting for processes whose transition times exceed, at best, microseconds. This limitation severely impacts, among others, a realistic assessment of slow-strain-rate mechanical behavior. In this work, using a simple paradigmatical model of a metallic nanopillar that is often the subject of experimental works, we attempt to circumvent the time-scale bottleneck of conventional molecular dynamics and provide novel physical insights into the rate-dependence of mechanical behavior of nanostructures...
June 8, 2016: Nano Letters
Jinxi Huang, Hao Hu, Zhewei Wang, Wenyuan Li, Ji Cang, Jianqi Shen, Hui Ye
In this paper, a nano-pillar array integrated near quantum dots (QDs), which serves as a Purcell cavity as well as a column antenna, is studied in order to enhance the spontaneous emission (SE) rate of low emission efficiency QDs. A systematic analysis for treating the isolated nano-pillar and loose ordered pillar is demonstrated by solving the electromagnetic field equations. As an illustrative example of potential applications, we proposed a new structure that Germanium (Ge) QDs are located in close proximity to the isolated Indium Tin Oxide (ITO) nano-pillar to raise its efficiency...
April 18, 2016: Optics Express
Cholho Lee, Kyung-Hoon Han, Kwon-Hyeon Kim, Jang-Joo Kim
We have demonstrated a simple and efficient method to fabricate OLEDs with enhanced out-coupling efficiencies and with low pixel blurring by inserting nano-pillar arrays prepared through the lateral phase separation of two immiscible polymers in a blend film. By selecting a proper solvent for the polymer and controlling the composition of the polymer blend, the nano-pillar arrays were formed directly after spin-coating of the polymer blend and selective removal of one phase, needing no complicated processes such as nano-imprint lithography...
March 21, 2016: Optics Express
Xuan Wu, Lei Gao, Xiao-Yu Hu, Leyong Wang
Supramolecular drug delivery systems (SDDSs), including various kinds of nanostructures that are assembled by reversible noncovalent interactions, have attracted considerable attention as ideal drug carriers owing to their fascinating ability to undergo dynamic switching of structure, morphology, and function in response to various external stimuli, which provides a flexible and robust platform for designing and developing functional and smart supramolecular nano-drug carriers. Pillar[n]arenes represent a new generation of macrocyclic hosts, which have unique structures and excellent properties in host-guest chemistry...
June 2016: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
Pawan K Kanaujia, G Vijaya Prakash
Non-contact bi-directional micropatterning of two-dimensional (2D) layered inorganic-organic (IO) perovskite [(R-NH3)2PbI4, R = organic moiety] thin films by direct laser writing (DLW) has been reported. These 2D materials are in the form of natural multiple quantum well (MQW) structures and show excitonic luminescence at room temperature because of quantum and dielectric confinement effects. Systematic optical and structural analyses of these laser processed hybrid systems provide an insight into laser-matter interaction and a pathway to develop technology to define complex 2D material based devices with new functionalities...
April 14, 2016: Physical Chemistry Chemical Physics: PCCP
Nichole A Crane, Nickolay V Lavrik, Michael J Sepaniak
An advantage of separation platforms based on deterministic micro- and nano-fabrications, relative to traditional systems based on packed beds of particles, is the exquisite control of all morphological parameters. For example, with planar platforms based on lithographically-prepared pillar arrays, the size, shape, height, geometric arrangement, and inter pillar gaps can be independently adjusted. Since the inter pillar gap is expected to be important in determining resistance to mass transfer in the mobile phase as well as the flow rate, which influences the mass transfer effect and axial diffusion, we herein study the effect of reducing inter pillar gaps on capillary action-based flow and band dispersion...
February 21, 2016: Analyst
Yu-Min Chen, Shih-Ming He, Chi-Hsien Huang, Cheng-Chun Huang, Wen-Pin Shih, Chun-Lin Chu, Jing Kong, Ju Li, Ching-Yuan Su
In this work, we fabricate ultra-large suspended graphene membranes, where stacks of a few layers of graphene could be suspended over a circular hole with a diameter of up to 1.5 mm, with a diameter to thickness aspect ratio of 3 × 10(5), which is the record for free-standing graphene membranes. The process is based on large crystalline graphene (∼55 μm) obtained using a chemical vapor deposition (CVD) method, followed by a gradual solvent replacement technique. Combining a hydrogen bubbling transfer approach with thermal annealing to reduce polymer residue results in an extremely clean surface, where the ultra-large suspended graphene retains the intrinsic features of graphene, including phonon response and an enhanced carrier mobility (200% higher than that of graphene on a substrate)...
February 14, 2016: Nanoscale
Eric Moyen, Adel Hama, Esma Ismailova, Loic Assaud, George Malliaras, Margrit Hanbücken, Roisin M Owens
UNLABELLED: We propose a facile and reproducible method, based on ultra thin porous alumina membranes, to produce cm(2) ordered arrays of nano-pores and nano-pillars on any kind of substrates. In particular our method enables the fabrication of conducting polymers nano-structures, such as poly[3,4-ethylenedioxythiophene]:poly[styrene sulfonate] ( PEDOT: PSS). Here, we demonstrate the potential interest of those templates with controlled cell adhesion studies. The triggering of the eventual fate of the cell (proliferation, death, differentiation or migration) is mediated through chemical cues from the adsorbed proteins and physical cues such as surface energy, stiffness and topography...
February 19, 2016: Nanotechnology
Francesco Gentile, Lorenzo Ferrara, Marco Villani, Manuele Bettelli, Salvatore Iannotta, Andrea Zappettini, Mario Cesarelli, Enzo Di Fabrizio, Nicola Coppedè
PEDOT: PSS is a conductive polymer that can be integrated into last generation Organic Electrochemical Transistor (OECT) devices for biological inspection, identification and analysis. While a variety of reports in literature demonstrated the chemical and biological sensitivity of these devices, still their ability in resolving complex mixtures remains controversial. Similar OECT devices display good time dynamics behavior but lack spatial resolution. In this work, we integrated PEDOT: PSS with patterns of super-hydrophobic pillars in which a finite number of those pillars is independently controlled for site-selective measurement of a solution...
2016: Scientific Reports
FengChao Wang, HengAn Wu
Understanding and controlling the motion of the contact line is of critical importance for surface science studies as well as many industrial engineering applications. In this work, we elucidate the molecular origin of contact line stick-slip motion during the evaporation of liquid droplets on flexible nano-pillared surfaces using molecular dynamics simulations. We demonstrate that the evaporation-induced stick-slip motion of the contact line is a consequence of competition between pinning and depinning forces...
2015: Scientific Reports
Sean M Gibbons, Jack A Gilbert
Microorganisms are the pillars of life on Earth. Over billions of years, they have evolved into every conceivable niche on the planet. Microbes reshaped the oceans and atmosphere and gave rise to conditions conducive to multicellular organisms. Only in the past decade have we started to peer deeply into the microbial cosmos, and what we have found is amazing. Microbial ecosystems behave, in many ways, like large-scale ecosystems, although there are important exceptions. We review recent advances in our understanding of how microbial diversity is distributed across environments, how microbes influence the ecosystems in which they live, and how these nano-machines might be harnessed to advance our understanding of the natural world...
December 2015: Current Opinion in Genetics & Development
Yixiao Cai, Fredrik Edin, Zhe Jin, Andrei Alexsson, Olafur Gudjonsson, Wei Liu, Helge Rask-Andersen, Mikael Karlsson, Hao Li
UNLABELLED: Cochlear implants (CI) have been used for several decades to treat patients with profound hearing loss. Nevertheless, results vary between individuals, and fine hearing is generally poor due to the lack of discrete neural stimulation from the individual receptor hair cells. A major problem is the deliverance of independent stimulation signals to individual auditory neurons. Fine hearing requires significantly more stimulation contacts with intimate neuron/electrode interphases from ordered axonal re-growth, something current CI technology cannot provide...
February 2016: Acta Biomaterialia
H S Grewal, Shuxue Piao, Il-Joo Cho, Kyung-Young Jhang, Eui-Sung Yoon
Surface modification is a promising method to solve the tribological problems in microsystems. To modify the surface, we fabricated hierarchical patterns with different pitches of nano-scale features and different surface chemistries. Micro- and nano-patterns with similar geometrical configurations were also fabricated for comparison. The nano-tribological behavior of the patterns was investigated using an atomic force microscope at different relative humidity levels (5% to 80%) and applied normal loads (40 nN to 120 nN) under a constant sliding velocity...
January 21, 2016: Soft Matter
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