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nano pillar

Marina Scharin-Mehlmann, Aaron Häring, Mathias Rommel, Tobias Dirnecker, Oliver Friedrich, Lothar Frey, Daniel F Gilbert
Polydimethylsiloxane (PDMS) is a promising biomaterial for generating artificial extracellular matrix (ECM) like patterned topographies, yet its hydrophobic nature limits its applicability to cell-based approaches. Although plasma treatment can enhance the wettability of PDMS, the surface is known to recover its hydrophobicity within a few hours after exposure to air. To investigate the capability of a novel PDMS-type (X-PDMS) for in vitro based assessment of physiological cell properties, we designed and fabricated plane as well as nano- and micrometer-scaled pillar-patterned growth substrates using the elastomer types S-, H- and X-PDMS, which were fabricated from commercially available components...
2018: Frontiers in Bioengineering and Biotechnology
Reza Abazari, Ghazal Salehi, Ali Reza Mahjoub
Using a green and simple route with ultrasound illumination under atmospheric pressure and at room temperature, the nanosized preparation of a Zn(II) metal-organic framework, [Zn(ATA)(BPD)]∞ (ATA = 2-aminoterephthalic acid), BPD = 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene), having nano-plate shape and 3D channel framework, was considered and the product was named as compound 1. The X-ray diffraction (XRD), scanning electron microscopy (SEM), IR spectroscopy, Brunauer-Emmett-Teller (BET), and thermogravimetric analysis (TGA) were used for characterization of the synthesized micro/nano-structures...
September 2018: Ultrasonics Sonochemistry
Sajad Moradi, Salar Khaledian, Mohadese Abdoli, Mohsen Shahlaei, Danial Kahrizi
Detection and quantification of various biological and non-biological species today is one of the most important pillars of all experimental sciences, especially sciences related to human health. This may apply to a chemical in the factory wastewater or to identify a cancer cell in a person's body, it may be apply to trace a useful industrial microorganism or human or plant pathogenic microorganisms. In this regard, scientists from various sciences have always striven to design and provide tools and techniques for identifying and quantifying as accurately as possible to trace various analyte types with greater precision and specificity...
April 30, 2018: Cellular and Molecular Biology
Kaito Yamada, Michihiro Yamada, Hideyuki Maki, Kohei M Itoh
Fabrication of a 2D square lattice array of intentionally tapered micro-/nano- silicon pillars by metal-assisted chemical etching (MACE) of silicon wafers is reported. The pillars are square rod shaped with the cross-sections in the range 0.2×0.2 - 0.9×0.9 µm<sup>2</sup> and heights 3-7 µm. The spacing between pillars in the 2D square lattice was controlled between 0.5 and 3.0 µm. While the pillars after MACE had the high aspect ratio ~1:5, subsequent anisotropic wet etching in potassium hydroxide solution led to 80-89...
April 26, 2018: Nanotechnology
Marouane Mastari, Matthew Charles, Yann Bogumilowicz, Quang Minh Thai, Patricia Pimenta Barros, Maxime Argoud, Anne-Marie Papon, Patrice Gergaud, Didier Landru, Youngpil Kim, Jean Michel Hartmann
In this paper, SiGe nano-heteroepitaxy on Si and SiGe nano-pillars was investigated in a 300 mm industrial Reduced Pressure-Chemical Vapour Deposition tool. An integration scheme based on diblock copolymer patterning was used to fabricate nanometer-sized templates for the epitaxy of Si and SiGe nano-pillars. Results showed highly selective and uniform processes for the epitaxial growth of Si and SiGe nano-pillars. 200 nm thick SiGe layers were grown on Si and SiGe nano-pillars and characterized by AFM, XRD and TEM...
April 12, 2018: Nanotechnology
Siqi Ying, Lifeng Ma, Tan Sui, Chrysanthi Papadaki, Enrico Salvati, Leon Romano Brandt, Hongjia Zhang, Alexander M Korsunsky
Nickel superalloys play a pivotal role in enabling power-generation devices on land, sea, and in the air. They derive their strength from coherent cuboidal precipitates of the ordered γ' phase that is different from the γ matrix in composition, structure and properties. In order to reveal the correlation between elemental distribution, dislocation glide and the plastic deformation of micro- and nano-sized volumes of a nickel superalloy, a combined in situ nanoindentation compression study was carried out with a scanning electron microscope (SEM) on micro- and nano-pillars fabricated by focused ion beam (FIB) milling of Ni-base superalloy CMSX4...
April 5, 2018: Materials
Kerwin Kwek Zeming, Thoriq Salafi, Swati Shikha, Yong Zhang
Disease diagnostics requires detection and quantification of nano-sized bioparticles including DNA, proteins, viruses, and exosomes. Here, a fluorescent label-free method for sensitive detection of bioparticles is explored using a pillar array with micrometer-sized features in a deterministic lateral displacement (DLD) device. The method relies on measuring changes in size and/or electrostatic charges of 1 µm polymer beads due to the capture of target bioparticles on the surface. These changes can be sensitively detected through the lateral displacement of the beads in the DLD array, wherein the lateral shifts in the output translates to a quantitative measurement of bioparticles bound to the bead...
March 28, 2018: Nature Communications
Shan Zhang, Baojin Ma, Feng Liu, Jiazhi Duan, Shicai Wang, Jichuan Qiu, Dong Li, Yuanhua Sang, Chao Liu, Duo Liu, Hong Liu
Numerous studies have determined that physical cues, especially the nanotopography of materials, play key roles in directing stem cell differentiation. However, most research on nanoarrays for stem cell fate regulation is based on nonbiodegradable materials, such as silicon wafers, TiO2 , and poly(methyl methacrylate), which are rarely used as tissue engineering biomaterials. In this study, we prepared biodegradable polylactic acid (PLA) nanopillar arrays with different diameters but the same center-to-center distance using a series of anodic aluminum oxide nanowell arrays as templates...
April 11, 2018: Nano Letters
Songmei Wu, Flavia Zuber, Katharina Maniura-Weber, Juergen Brugger, Qun Ren
BACKGROUND: Due to the increased emergence of antimicrobial resistance, alternatives to minimize the usage of antibiotics become attractive solutions. Biophysical manipulation of material surface topography to prevent bacterial adhesion is one promising approach. To this end, it is essential to understand the relationship between surface topographical features and bactericidal properties in order to develop antibacterial surfaces. RESULTS: In this work a systematic study of topographical effects on bactericidal activity of nanostructured surfaces is presented...
February 28, 2018: Journal of Nanobiotechnology
Pierre Champigneux, Cyril Renault-Sentenac, David Bourrier, Carole Rossi, Marie-Line Delia, Alain Bergel
Smooth and nano-rough flat gold electrodes were manufactured with controlled Ra of 0.8 and 4.5nm, respectively. Further nano-rough surfaces (Ra 4.5nm) were patterned with arrays of micro-pillars 500μm high. All these electrodes were implemented in pure cultures of Geobacter sulfurreducens, under a constant potential of 0.1V/SCE and with a single addition of acetate 10mM to check the early formation of microbial anodes. The flat smooth electrodes produced an average current density of 0.9A·m-2 . The flat nano-rough electrodes reached 2...
June 2018: Bioelectrochemistry
Dianzhong Chen, Xiaowei Liu, Haifeng Zhang, Hai Li, Rui Weng, Ling Li, Wanting Rong, Zhongzhao Zhang
Stable rotor levitation is a challenge for rotational gyroscopes (magnetically suspended gyroscopes (MSG) and electrostatically suspended gyroscopes (ESG)) with a ring- or disk-shaped rotor, which restricts further improvement of gyroscope performance. In addition, complicated pick-up circuits and feedback control electronics propose high requirement on fabrication technology. In the proposed gyroscope, a ball-disk shaped rotor is supported by a water-film bearing, formed by centrifugal force to deionized water at the cavity of the lower supporting pillar...
January 31, 2018: Sensors
Yang Yang, Yong Gang Li, Michael P Short, Chung-Soo Kim, Karl K Berggren, Ju Li
Full three dimensional (3D) simulations of ion implantation are necessary in a wide range of nanoscience and nanotechnology applications to capture the increasing effect of ion leakage out of surfaces. Using a recently developed 3D Monte Carlo simulation code IM3D, we first quantify the relative error of the 1D approach in three applications of nano-scale ion implantation: (1) nano-beam for nitrogen-vacancy (NV) center creation, (2) implantation of nanowires to fabricate p-n junctions, and (3) irradiation of nano-pillars for small-scale mechanical testing of irradiated materials...
January 25, 2018: Nanoscale
Peng Huang, Qian Yu
"Smaller is stronger" has been commonly observed in cubic structured and hexagonal close-packed (HCP) structured materials. Dislocation starvation phenomenon is highly responsible for the increase of strength at smaller scale in cubic materials. However, by using quantitative in situ transmission electron microscope (TEM) nano-mechanical testing on cylindrical titanium nano-pillars with diameters of ~150 nm but varied orientations and three dimensional dislocation tomography, we found that dislocation nucleation and multiplication dominate the plastic deformation of the nano-pillars with no sign of dislocation starvation, resulting in much better ability of dislocation storage and plastic stability of HCP structured materials at extremely small scale...
November 21, 2017: Scientific Reports
Sayed Ali Akbar Razavi, Mohammad Yaser Masoomi, Ali Morsali
A pillared MOF, [Zn(OBA)(H2 DPT)0.5 ].DMF (TMU-34), based on dihydro tetrazine functionalized pillar spacer (H2 DPT=3,6-di(pyridin-4-yl)-1,4-dihydro-1,2,4,5-tetrazine) and V-shape dicarboxylate linker (H2 OBA=4,4'-oxybis(benzoic acid)) was synthesized by reflux and ultrasonic methods. The effects of sonication time, initial concentration of reagents and sonication power on size and morphology have been optimized. This MOF has been characterized by scanning electron microscopy, FT-IR spectra, X-ray powder diffraction and N2 adsorption at 77K...
March 2018: Ultrasonics Sonochemistry
Qun Wang, Menghao Wang, Xiong Lu, Kefeng Wang, Liming Fang, Fuzeng Ren, Guoming Lu
Hydroxyapatite (HA) is the principal inorganic component of bones and teeth and has been widely used as a bone repair material because of its good biocompatibility and bioactivity. Understanding the interactions between proteins and HA is crucial for designing biomaterials for bone regeneration. In this study, we evaluated the effects of atomic-level nano-structured HA (110) surfaces on the adsorption of bone morphogenetic protein-7 (BMP-7) and its derived peptide (KQLNALSVLYFDD) using molecular dynamics and density functional theory methods...
November 9, 2017: Scientific Reports
Shasha Qiao, Shen Li, Qunyang Li, Bo Li, Kesong Liu, Xi-Qiao Feng
Liquid transport is a fundamental process relevant to a wide range of applications, for example, heat transfer, anti-icing, self-cleaning, drag reduction, and microfluidic systems. For these applications, a deeper understanding of the sliding behavior of water droplets on solid surfaces is of particular importance. In this study, the frictional behavior of water droplets sliding on superhydrophobic surfaces decorated with micropillar arrays was studied using a nanotribometer. Our experiments show that surfaces with a higher solid area fraction generally exhibited larger friction, although friction might drop when the solid area fraction was close to unity...
November 28, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
Guillaume Raffy, Robin Bofinger, Arnaud Tron, André Del Guerzo, Nathan D McClenaghan, Jean-Marc Vincent
An innovative photopatterning process is described that allows, in a single laser-promoted operation, the covalent attachment of a molecule on a surface (2D patterning - xy dimensions) and its photopolymerization to grow micro-/nanostructures with spatial control in a third z-dimension. The surface patterning process, based on nitrene reactivity, was harnessed using the highly fluorescent azide-substituted boron difluoride dipyrromethene (BODIPY) 1 that was prepared in a single synthetic step from the parent pentafluorophenyl BODIPY on reacting with NaN3...
November 9, 2017: Nanoscale
Loïc Berthod, Olga Shavdina, Isabelle Verrier, Thomas Kämpfe, Olivier Dellea, Francis Vocanson, Maxime Bichotte, Damien Jamon, Yves Jourlin
This paper presents substantial improvements of the colloidal photolithography technique (also called microsphere lithography) with the goal of better controlling the geometry of the fabricated nano-scale structures-in this case, hexagonally arranged nanopillars-printed in a layer of directly photopatternable sol-gel TiO₂. Firstly, to increase the achievable structure height the photosensitive layer underneath the microspheres is deposited on a reflective layer instead of the usual transparent substrate. Secondly, an increased width of the pillars is achieved by tilting the incident wave and using multiple exposures or substrate rotation, additionally allowing to better control the shape of the pillar's cross section...
October 12, 2017: Nanomaterials
Shan Gao, Quanwen Liao, Wei Liu, Zhichun Liu
Recently, numerous studies focused on the wetting process of droplets on various surfaces at a microscale level. However, there are a limited number of studies about the mechanism of condensation on patterned surfaces. The present study performed the dynamic wetting behavior of water droplets and condensation process of water molecules on substrates with different pillar structure parameters, through molecular dynamic simulation. The dynamic wetting results indicated that droplets exhibit Cassie state, PW state, and Wenzel state successively on textured surfaces with decreasing solid fraction...
October 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
Jon Ashley, Kaiyu Wu, Mikkel Fougt Hansen, Michael Stenbæk Schmidt, Anja Boisen, Yi Sun
There is an increasing demand for rapid, sensitive, and low cost analytical methods to routinely screen antibiotic residues in food products. Conventional detection of antibiotics involves sample preparation by liquid-liquid or solid-phase extraction, followed by analysis using liquid chromatography-mass spectrometry (LC-MS), capillary electrophoresis (CE), or gas chromatography (GC). The process is labor-intensive, time-consuming, and expensive. In this study, we developed a new analytical method that combines magnetic molecularly imprinted polymer (MMIP)-based sample preparation with surface-enhanced Raman spectroscopy (SERS)-based detection for quantitative analysis of cloxacillin in pig serum...
November 7, 2017: Analytical Chemistry
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