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https://www.readbyqxmd.com/read/29148413/variable-impacts-of-different-remission-states-on-health-related-quality-of-life-in-rheumatoid-arthritis
#1
Margaret H Y Ma, Fowzia Ibrahim, Gabrielle H Kingsley, Andrew Cope, David L Scott
OBJECTIVES: Targeting remission in rheumatoid arthritis (RA) improves health-related quality of life (HRQoL) and disability. However, the impacts of different remission criteria and durations and their frequencies are uncertain. Our observational study assessed these factors. METHODS: We recruited RA patients with disease durations <10 years, stable suppressive therapies and stable disease activity scores for 28 joints using ESR (DAS28-ESR) ≤3.2. Intermittent and sustained remisisons were classified using DAS28ESR, simple disease activity index (SDAI) and ACR/EULAR Boolean criteria...
October 23, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29129663/compensation-strategies-in-voice-production-with-glottal-insufficiency
#2
Zhaoyan Zhang
OBJECTIVES: This study evaluates potential compensation strategies under conditions of glottal insufficiency. METHODS: Using a numerical respiratory-laryngeal model of voice production, voice production under conditions of glottal insufficiency is investigated across a large range of voice conditions, and compared with normal voice production. RESULTS: This study shows that glottal insufficiency leads to increased noise production, reduced fundamental frequency range, and inability to produce very low-intensity voice...
November 9, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29122618/effects-of-tai-chi-exercise-on-cancer-related-fatigue-in-patients-with-nasopharyngeal-carcinoma-undergoing-chemoradiotherapy-a-randomized-controlled-trial
#3
Wei Zhou, Yong-Hui Wan, Qian Chen, Yan-Ru Qiu, Xiao-Min Luo
CONTEXT: Tai Chi exercise has been shown to improve cancer-related fatigue (CRF) and autonomic nervous system (ANS) balance in some cancer patients or survivors, however, such effects are yet to be verified in nasopharyngeal carcinoma (NPC) patients undergoing chemoradiotherapy. OBJECTIVES: To explore the effects of Tai Chi exercise on CRF in NPC patients undergoing chemoradiotherapy and then to evaluate ANS information indicated by heart rate variability (HRV) parameters and their association with CRF...
November 6, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29116645/the-impact-of-physical-activity-on-fatigue-and-quality-of-life-during-and-after-adjuvant-treatment-for-breast-cancer
#4
Florian Manneville, Christine Rotonda, Thierry Conroy, Franck Bonnetain, Francis Guillemin, Abdou Y Omorou
BACKGROUND: Although physical activity (PA) can alleviate fatigue and improve quality of life (QoL) in patients with breast cancer (BC), not all domains of PA may have equal impact. The objective of the current study was to examine the longitudinal impact of PA components on the evolution of fatigue and QoL during and after adjuvant treatment for BC. METHODS: The women included in the study were participants in the 2-year longitudinal FATSEIN ("Fatigue dans le cancer du Sein") study...
November 8, 2017: Cancer
https://www.readbyqxmd.com/read/29112627/impact-of-blood-flow-restriction-exercise-on-muscle-fatigue-development-and-recovery
#5
Florian Husmann, Thomas Mittlmeier, Sven Bruhn, Volker Zschorlich, Martin Behrens
PURPOSE: The present study was designed to provide mechanistic insight into the time-course and etiology of muscle fatigue development and recovery during and after low-intensity exercise when it is combined with blood flow restriction (BFR). METHODS: Seventeen resistance-trained males completed four sets of low-intensity isotonic resistance exercise under two experimental conditions: knee extension exercise combined with (i) BFR and (ii) without BFR (CON). Neuromuscular tests were performed before, during (immediately after each set of knee extension exercise) and 1, 2, 4, and 8 min after each experimental condition...
November 6, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29084357/adverse-events-associated-with-medium-and-long-term-use-of-opioids-for-chronic-non-cancer-pain-an-overview-of-cochrane-reviews
#6
REVIEW
Charl Els, Tanya D Jackson, Diane Kunyk, Vernon G Lappi, Barend Sonnenberg, Reidar Hagtvedt, Sangita Sharma, Fariba Kolahdooz, Sebastian Straube
BACKGROUND: Chronic pain is common and can be challenging to manage. Despite increased utilisation of opioids, the safety and efficacy of long-term use of these compounds for chronic non-cancer pain (CNCP) remains controversial. This overview of Cochrane Reviews complements the overview entitled 'High-dose opioids for chronic non-cancer pain: an overview of Cochrane Reviews'. OBJECTIVES: To provide an overview of the occurrence and nature of adverse events associated with any opioid agent (any dose, frequency, or route of administration) used on a medium- or long-term basis for the treatment of CNCP in adults...
October 30, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29079651/frequency-duration-and-cause-of-ventilator-alarms-on-a-neonatal-intensive-care-unit
#7
Gusztav Belteki, Colin J Morley
OBJECTIVE: To investigate the frequency and cause of neonatal ventilator alarms. Neonatal ventilators frequently alarm and also disturb babies, parents and nurses. If frequent they may cause alarm fatigue and be ignored. The number, frequency and details of neonatal ventilator alarms are unreported. METHODS: We developed programs for retrieving and analysing ventilator data each second on alarms and ventilation parameters from 46 babies ventilated with Dräger Babylog VN500 ventilators using various modes...
October 27, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29072728/lead-free-bnt-based-composite-materials-enhanced-depolarization-temperature-and-electromechanical-behavior
#8
Wangfeng Bai, Peng Zheng, Fei Wen, Jingji Zhang, Daqin Chen, Jiwei Zhai, Zhenguo Ji
The development of (Bi0.5Na0.5)TiO3-based solid solutions with both high depolarization temperature Td and excellent piezoelectric and electromechanical properties for practical application is intractable because improved thermal stability is usually accompanied by a deterioration in piezoelectric and electromechanical performance. Herein, we report a 0-3 type 0.93(Bi0.5Na0.5)TiO3-0.07BaTiO3 : 30 mol%ZnO composite (BNT-7BT : 0.3ZnO), in which the ZnO nanoparticles exist in two forms, to resolve the abovementioned long-standing obstacle...
November 14, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29058083/exercise-program-design-considerations-for-head-and-neck-cancer-survivors
#9
Adrian W Midgley, Derek Lowe, Andrew R Levy, Vishal Mepani, Simon N Rogers
The present study aimed to establish exercise preferences, barriers, and perceived benefits among head and neck cancer survivors, as well as their level of interest in participating in an exercise program. Patients treated for primary squamous cell carcinoma of the head and neck between 2010 and 2014 were identified from the hospital database and sent a postal questionnaire pack to establish exercise preferences, barriers, perceived benefits, current physical activity levels, and quality of life. A postal reminder was sent to non-responders 4 weeks later...
October 20, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29045954/-pulmonary-arterial-hypertension-as-leading-manifestation-of-methylmalonic-aciduria-clinical-characteristics-and-gene-testing-in-15-cases
#10
X Q Liu, H Yan, J X Qiu, C Y Zhang, J G Qi, X Zhang, H J Xiao, Y L Yang, Y H Chen, J B DU
OBJECTIVE: To deepen our understanding of Methylmalonic aciduria (MMA) associated pulmonary hypertension (PH) by analyzing the characteristics of clinical presentation, pulmonary high resolusion CT(HRCT), treatment response and gene mutation. METHODS: This study includes 15 cases of pediatric patients with MMA associated PH diagnosed and treated in Peking University First Hospital pediatric department between May 2012 and May 2016 with symptoms of PH as their leading presentation...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045021/reduced-dietary-intake-of-micronutrients-with-antioxidant-properties-negatively-impacts-muscle-health-in-aged-mice
#11
Miriam van Dijk, Francina J Dijk, Anita Hartog, Klaske van Norren, Sjors Verlaan, Ardy van Helvoort, Richard T Jaspers, Yvette Luiking
BACKGROUND: Inadequate intake of micronutrients with antioxidant properties is common among older adults and has been associated with higher risk of frailty, adverse functional outcome, and impaired muscle health. However, a causal relationship is less well known. The aim was to determine in old mice the impact of reduced dietary intake of vitamins A/E/B6/B12/folate, selenium, and zinc on muscle mass, oxidative capacity, strength, and physical activity (PA) over time. METHODS: Twenty-one-month-old male mice were fed either AIN-93-M (control) or a diet low in micronutrients with antioxidant properties (=LOWOX-B: 50% of mouse recommended daily intake of vitamins A, E, B6, and B12, folate, selenium, and zinc) for 4 months...
October 16, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29044670/the-effect-of-blue-light-blocking-spectacle-lenses-on-visual-performance-macular-health-and-the-sleep-wake-cycle-a%C3%A2-systematic-review-of-the-literature
#12
REVIEW
John G Lawrenson, Christopher C Hull, Laura E Downie
PURPOSE: Blue-blocking (BB) spectacle lenses, which attenuate short-wavelength light, are being marketed to alleviate eyestrain and discomfort when using digital devices, improve sleep quality and potentially confer protection from retinal phototoxicity. The aim of this review was to investigate the relative benefits and potential harms of these lenses. METHODS: We included randomised controlled trials (RCTs), recruiting adults from the general population, which investigated the effect of BB spectacle lenses on visual performance, symptoms of eyestrain or eye fatigue, changes to macular integrity and subjective sleep quality...
November 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/29023327/sodium-bicarbonate-supplementation-delays-neuromuscular-fatigue-without-changes-in-performance-outcomes-during-a-basketball-match-simulation-protocol
#13
Paul Ansdell, Jeanne Dekerle
PURPOSE: To investigate the development of neuromuscular fatigue during a basketball game simulation and ascertain whether sodium bicarbonate (NaHCO3) supplementation attenuates any neuromuscular fatigue that persists. METHODS: Ten participants ingested 0.2 g.kg of NaHCO3 (or an equimolar placebo dosage of sodium chloride [NaCl]) 90 and 60 minutes prior to commencing a basketball game simulation (ALK-T vs PLA-T). Isometric maximal voluntary contractions of the knee extensors (MVIC) and potentiated high (100 Hz) and low (10 Hz) frequency doublet twitches were recorded before and after each match quarter for both trials...
October 10, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29020729/diagnosing-and-managing-androgen-deficiency-in-men
#14
REVIEW
Raveen Kaur Sandher, Jonathan Aning
Androgens play a crucial role in bone, muscle and fat metabolism, erythropoiesis and cognitive health. In men aged 40-79 years the incidence of biochemical deficiency and symptomatic hypogonadism is 2.1-5.7%. Decreased libido or reduced frequency and quality of erections, fatigue, irritability, infertility or a diminished feeling of wellbeing may be presenting complaints. However, a significant proportion of men with androgen deficiency will be identified when they present for unrelated concerns. Important factors to elicit from the history in addition to the presenting complaint include: a medical history of obesity, type 2 diabetes, systemic diseases or metabolic syndrome which all impact on testosterone physiology...
April 2017: Practitioner
https://www.readbyqxmd.com/read/28991429/drastically-enhancing-moduli-of-graphene-coated-carbon-nanotube-aerogels-via-densification-while-retaining-temperature-invariant-superelasticity-and-ultrahigh-efficiency
#15
Michelle N Tsui, Kyu Hun Kim, Mohammad F Islam
Lightweight open-cell foams that are simultaneously superelastic, possess exceptionally high Young's moduli (Y), exhibit ultrahigh efficiency, and resist fatigue as well as creep are particularly desirable as structural frameworks. Unfortunately, many of these features are orthogonal in foams of metals, ceramics, and polymers, particularly under large temperature variations. In contrast, foams of carbon allotropes including carbon nanotubes and graphene developed over the past few years exhibit these desired properties but have low Y due to low density, ρ = 0...
October 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28979212/muscle-shear-moduli-changes-and-frequency-of-alternate-muscle-activity-of-plantar-flexor-synergists-induced-by-prolonged-low-level-contraction
#16
Ryota Akagi, Takahito Fukui, Masato Kubota, Masashi Nakamura, Ryoichi Ema
During prolonged low-level contractions, synergist muscles are activated in an alternating pattern of activity and silence called as alternate muscle activity. Resting muscle stiffness is considered to increase due to muscle fatigue. Thus, we investigated whether the difference in the extent of fatigue of each plantar flexor synergist corresponded to the difference in the frequency of alternate muscle activity between the synergists using muscle shear modulus as an index of muscle stiffness. Nineteen young men voluntarily participated in this study...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28972685/effects-of-manipulating-tetanic-calcium-on-the-curvature-of-the-force-velocity-relationship-in-isolated-rat-soleus-muscles
#17
A M Kristensen, O B Nielsen, K Overgaard
AIM: In dynamically contracting muscles, increased curvature of the force-velocity relationship contributes to the loss of power during fatigue. It has been proposed that fatigue-induced reduction in [Ca(++) ]i causes this increased curvature. However, earlier studies on single fibers have been conducted at low temperatures. Here, we investigated the hypothesis that curvature is increased by reductions in tetanic [Ca(++) ]i in isolated skeletal muscle at near-physiological temperatures...
October 3, 2017: Acta Physiologica
https://www.readbyqxmd.com/read/28951860/vocal-symptoms-and-acoustic-findings-in-menopausal-women-in-comparison-to-pre-menopause-women-with-body-mass-index-as-a-confounding-variable
#18
Abdul-Latif Hamdan, Georges Ziade, Georges Tabet, Rachel Btaiche, Ghina Fakhri, Firas Yatim, Doja Sarieddine, Muhieddine Seoud
OBJECTIVES: To compare the prevalence of phonatory symptoms in menopausal women compared to pre-menopause women with body mass index (BMI) as a confounding variable. METHODS: A total of 69 women, 34 menopausal and 35 pre-menopausal were invited to participate in this study. Demographic variables included age, smoking, and BMI. All subjects were asked about the presence hoarseness, loss of high or low frequencies, pitch breaks, throat clearing, dryness in the throat and vocal fatigue...
August 2017: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/28942714/myoelectric-manifestation-of-muscle-fatigue-in-repetitive-work-detected-by-means-of-miniaturized-semg-sensors
#19
Alberto Ranavolo, Giorgia Chini, Alessio Silvetti, Silvia Mari, Mariano Serrao, Francesco Draicchio
Upper limb work-related musculoskeletal disorders have a 12-month prevalence ranging from 12 to 41% worldwide and can be partly caused by handling low loads at high frequency. The association between the myoelectric manifestation of elbow flexor muscle fatigue and occupational physical demand has never been investigated. It was hypothesized that an elbow flexor muscle fatigue index could be a valid risk indicator in handling low loads at high frequency. This study aims to measure the myoelectric manifestation of muscle fatigue of the three elbow flexor muscles during the execution of the work tasks in different risk conditions...
September 25, 2017: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/28936572/spa-therapy-balneotherapy-relieves-mental-stress-sleep-disorder-and-general-health-problems-in-sub-healthy-people
#20
Bei Yang, Qi-Zhong Qin, Ling-Li Han, Jing Lin, Yu Chen
To investigate the relieving effects of hot spring balneotherapy on mental stress, sleep disorder, general health problems, and women's health problems in sub-healthy people, we recruited 500 volunteers in sub-health in Chongqing, and 362 volunteers completed the project, including 223 in the intervention group and 139 in the control group. The intervention group underwent hot spring balneotherapy for 5 months, while the control group did not. The two groups took questionnaire investigation (general data, mental stress, emotional status, sleep quality, general health problems, as well as some women's health problems) and physical examination (height, weight, waist circumference, blood pressure, blood lipid, blood sugar) 5 months before and after the intervention, respectively...
September 21, 2017: International Journal of Biometeorology
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