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https://www.readbyqxmd.com/read/27900297/effects-of-lymphatic-drainage-and-local-cryo-exposition-regeneration-after-high-intensive-exercises
#1
Michael Behringer, Diana Jedlicka, Molly McCourt, Matthias Ring, Joachim Mester
BACKGROUND: Recovery from exercise and competition is important in sports medicine, particularly when rest periods are short. The objective is to determine the efficacy of cryo exposition (CRY) and manual lymphatic drainage (MLD) to hasten short term recovery of muscle performance after eccentric contractions. METHODS: In a randomized controlled trial, 30 healthy sport students (21 males, 9 females; age: 25.7±2.8 years) performed 4×20 eccentric contractions of knee extensors, followed by 30 min MLD, CRY, or rest (RST) under controlled laboratory environment...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27869319/the-ca-2-sensitizer-ck-2066260-increases-myofibrillar-ca-2-sensitivity-and-submaximal-force-selectively-in-fast-skeletal-muscle
#2
Darren T Hwee, Arthur J Cheng, James J Hartman, Aaron C Hinken, Ken Lee, Nickie Durham, Alan J Russell, Fady I Malik, Håkan Westerblad, Jeffrey R Jasper
Skeletal muscle dysfunction occurs in many diseases and can lead to muscle weakness and premature muscle fatigue. Here we show that the fast skeletal troponin activator, CK-2066260, counteracts muscle weakness by increasing troponin Ca(2+) affinity, thereby increasing myofibrillar Ca(2+) sensitivity. Exposure to CK-2066260 resulted in a concentration-dependent increase in the Ca(2+) sensitivity of ATPase activity in isolated myofibrils and reconstituted hybrid sarcomeres containing fast skeletal muscle troponin C...
November 21, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27822928/factors-contributing-to-discordance-between-the-2011-acr-eular-criteria-and-physician-clinical-judgment-for-the-identification-of-remission-in-patients-with-rheumatoid-arthritis
#3
Yoon Kyoung Sung, Soo Kyung Cho, Dam Kim, Bo Young Yoon, Chan Bum Choi, Hoon Suk Cha, Jung Yoon Choe, Won Tae Chung, Seung Jae Hong, Jae Bum Jun, Young Mo Kang, Jinseok Kim, Tae Hwan Kim, Tae Jong Kim, Eunmi Koh, Choong Ki Lee, Jisoo Lee, Shin Seok Lee, Sung Won Lee, Hye Soon Lee, Yeon Ah Lee, Sung Hoon Park, Dae Hyun Yoo, Wan Hee Yoo, Sang Cheol Bae
Remission is a primary end point of in clinical practice and trials of treatments for rheumatoid arthritis (RA). The 2011 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) remission criteria were developed to provide a consensus definition of remission. This study aimed to assess the concordance between the new remission criteria and the physician's clinical judgment of remission and also to identify factors that affect the discordance between these two approaches. A total of 3,209 patients with RA were included from the KORean Observational Study Network for Arthritis (KORONA) database...
December 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27810980/wavelet-coherence-analysis-of-cerebral-oxygenation-signals-measured-by-near-infrared-spectroscopy-in-sailors-an-exploratory-experimental-study
#4
Lingguo Bu, Jianfeng Li, Fangyi Li, Heshan Liu, Zengyong Li
OBJECTIVE: The objective of this study was to assess the effects of long-term offshore work on cerebral oxygenation oscillations in sailors based on the wavelet phase coherence (WPCO) of near-infrared spectroscopy (NIRS) signals. METHODS: The fatigue severity scale (FSS) was first applied to assess the fatigue level of sailors and age-matched controls. Continuous recordings of NIRS signals were then obtained from the prefrontal lobes in 30 healthy sailors and 30 age-matched controls during the resting state...
November 3, 2016: BMJ Open
https://www.readbyqxmd.com/read/27798178/differential-expression-of-munc13-2-produces-unique-synaptic-phenotypes-in-the-basolateral-amygdala-of-c57bl-6j-and-dba-2j-mice
#5
Dominic A Gioia, Nancy J Alexander, Brian A McCool
: C57BL/6J (B6) and DBA/2J (D2) mice are well known to differentially express a number of behavioral phenotypes, including anxiety-like behavior, fear conditioning, and drug self-administration. However, the cellular mechanisms contributing to these differences remain unclear. Given the basolateral amygdala (BLA) contributes to these behaviors, we characterized strain-dependent differences in presynaptic and postsynaptic function in BLA neurons by integrating electrophysiological, biochemical, and genetic approaches to identify specific molecular mechanisms...
October 26, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27798141/fatigue-in-rapsyn-deficient-zebrafish-reflects-defective-transmitter-release
#6
Hua Wen, Jeffrey Michael Hubbard, Wei-Chun Wang, Paul Brehm
: Rapsyn-deficient myasthenic syndrome is characterized by a weakness in voluntary muscle contraction, a direct consequence of greatly reduced synaptic responses that result from poorly clustered acetylcholine receptors. As with other myasthenic syndromes, the general muscle weakness is also accompanied by use-dependent fatigue. Here, we used paired motor neuron target muscle patch-clamp recordings from a rapsyn-deficient mutant line of zebrafish to explore for the first time the mechanisms causal to fatigue...
October 19, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27772773/predictors-of-health-related-quality-of-life-in-people-with-amyotrophic-lateral-sclerosis
#7
Petter Sandstedt, Sverker Johansson, Charlotte Ytterberg, Caroline Ingre, Lotta Widén Holmqvist, Marie Kierkegaard
BACKGROUND: Knowledge of factors influencing health-related quality of life (HRQL) in people with amyotrophic lateral sclerosis (ALS) is important because some factors might be amenable to intervention. OBJECTIVES: The aim was to describe and explore the effects of disease severity, fatigue, anxiety, depression, frequency of social and lifestyle activities, coping capacity and mechanical ventilator use on HRQL in people with ALS. METHODS: Sixty people with ALS were enrolled in this cross-sectional study...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27771595/using-a-chewing-simulator-for-fatigue-testing-of-metal-ceramic-crowns
#8
S D Heintze, A Eser, D Monreal, V Rousson
OBJECTIVE: Dynamic loading is a more important predictor for the clinical longevity of ceramic crowns than static loading. However, dynamic loading machines are costly and mostly have only one test station. The SD Mechatronik Chewing Simulator (formerly Willytec) may be a cost-effective alternative to evaluate the fatigue resistance of metal ceramic crowns. METHOD: Four metal ceramic materials were tested on lower first molar crowns: GC InitiaI, Creation (Willy Geller), IPS InLine (Ivoclar Vivadent) and the new low-fusion IPS Style Ceram (Ivoclar Vivadent)...
September 14, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27766128/the-effect-of-skinfold-on-the-assessment-of-the-mean-power-frequency-at-the-fatigue-threshold
#9
Alyssandra N Baniqued, Jorge M Zuniga, Thomas C Strunc, Katie M Keenan, Agrini K Boken, Jeffrey J Anderson
The purpose of this study was to determine if the amount of subcutaneous tissue over the quadriceps affects the assessment of mean power frequency at the fatigue threshold (MPFFT). It was hypothesized that greater skinfold values will result in lower power outputs associated to the MPFFT. Fourteen adults (Mean ± SD age = 20.7 ± 0.99; body weight = 72.8 ± 12.6 kg) performed an incremental cycle ergometry test to exhaustion while surface electromyographic (EMG) signals were measured from the vastus lateralis...
2016: International Journal of Exercise Science
https://www.readbyqxmd.com/read/27756049/cyclic-loading-of-human-articular-cartilage-the-transition-from-compaction-to-fatigue
#10
Jonathan T Kaplan, Corey P Neu, Hicham Drissi, Nancy C Emery, David M Pierce
Osteoarthritis and articular cartilage injuries are common conditions in human joints and a frequent cause of pain and disability. Unfortunately, cartilage is avascular and has limited capabilities for self-repair. Despite the societal impact, there is little information on the dynamic process of cartilage degeneration. We performed a series of cyclic unconfined compression tests motivated by in vivo loading conditions and designed to generate mechanical fatigue. We examined the functional (both stress-stretch and creep) responses of the tissue after recovery from a specified number of loading cycles, as well as histology and second harmonic generation microscopy images...
October 1, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27753740/correlated-emg-oscillations-between-antagonists-during-co-contraction-in-men
#11
Yasuhide Yoshitake, Hiroaki Kanehisa, Minoru Shinohara
PURPOSE: The purpose of this study was to determine the modulation of common low-frequency oscillations in pools of motor units across antagonistic muscles due to the difference in the activation level of pools of spinal motor neurons and the presence of neuromuscular fatigue during intended co-contraction. METHODS: Ten healthy young men (21.8 ± 1.5 yr) performed intended steady co-contractions of elbow flexors and extensors at maximal and a submaximal (10% of maximal electromyogram, EMG) effort...
October 6, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27751859/abnormal-dynamics-of-cortical-resting-state-functional-connectivity-in-chronic-headache-patients
#12
Zewei Wang, Qing Yang, Li Min Chen
The goals of this study are to characterize the temporal dynamics of inter-regional connectivity of the brain in chronic headache (CH) patients versus their age/gender matched controls (CONCH, n=28 pairs), and to determine whether dynamic measures reveal additional features to static functional connectivity and correlate with psychometric scores. Cortical thickness and inter-regional resting state fMRI connectivity were quantified and compared between CH and CONCH groups. Six cortical regions of interest (ROI) pairs that exhibited correlated cortical thickness and static functional connectivity abnormalities were selected for temporal dynamic analysis...
October 14, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27684480/responsive-upper-limb-and-cognitive-fatigue-measures-during-light-precision-work-an-8-hour-simulated-micro-pipetting-study
#13
Marcus Yung, Richard P Wells
Many contemporary occupations are characterised by long periods of low loads. These lower force levels, which are relevant to the development of work-related musculoskeletal disorders, are usually not the focus of fatigue studies. In studies that did measure fatigue in light manual or precision work, within and between measurement responses were inconsistent. The aim of this study was to identify fatigue measures that were responsive at lower force levels (<10% MVC) over the course of an 8-h period. A complementary set of fatigue measures, reflecting both neuromuscular and cognitive mechanisms, was measured during a light precision micro-pipetting task performed by 11 participants...
October 14, 2016: Ergonomics
https://www.readbyqxmd.com/read/27673320/synaptic-reliability-and-temporal-precision-are-achieved-via-high-quantal-content-and-effective-replenishment-auditory-brainstem-versus-hippocampus
#14
Elisa G Krächan, Alexander U Fischer, Jürgen Franke, Eckhard Friauf
KEY POINTS: Auditory brainstem neurons involved in sound source localization are equipped with several morphological and molecular features that enable them to compute interaural level and time differences. As sound source localization works continually, synaptic transmission between these neurons should be reliable and temporally precise, even during sustained periods of high-frequency activity. Using patch-clamp recordings in acute brain slices, we compared synaptic reliability and temporal precision in the seconds-minute range between auditory and two types of hippocampal synapses; the latter are less confronted with temporally precise high-frequency transmission than the auditory ones...
September 26, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27661280/-iron-deficiency-anemia-as-a-factor-of-development-of-asthenia-syndrome
#15
G Muldaeva, N Rukaber, L Arystan, L Haydargalieva, Z Kenzhetaeva
The aim of this research was to determine the frequency and degree of severity of asthenic syndrome (AS) and estimation of physical health of women with iron-deficiency anemia (IDA) and without it. 30 women were inspected with the set diagnosis of IDA and 20 nearly were healthy. All participants were assessed according objective status. AS was determined by the scale of estimation of asthenia - Scale Asthenic Conditions (SAC) of LD Malkova, the scale of subjective evaluation of asthenia (MFI-20). Level of somatic health was appraised by methodology of LG Apanasenko...
July 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27645350/low-fat-plant-based-diet-in-multiple-sclerosis-a-randomized-controlled-trial
#16
Vijayshree Yadav, Gail Marracci, Edward Kim, Rebecca Spain, Michelle Cameron, Shannon Overs, Andrew Riddehough, David K B Li, John McDougall, Jesus Lovera, Charles Murchison, Dennis Bourdette
BACKGROUND: The role that dietary interventions can play in multiple sclerosis (MS) management is of huge interest amongst patients and researchers but data evaluating this is limited. Possible effects of a very-low-fat, plant-based dietary intervention on MS related progression and disease activity as measured by brain imaging and MS related symptoms have not been evaluated in a randomized-controlled trial. Despite use of disease modifying therapies (DMT), poor quality of life (QOL) in MS patients can be a significant problem with fatigue being one of the common disabling symptoms...
September 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27638148/low-level-laser-therapy-reduces-the-fatigue-index-in-the-ankle-plantar-flexors-of-healthy-subjects
#17
Clécio Gabriel de Souza, Daniel Tezoni Borges, Liane de Brito Macedo, Jamilson Simões Brasileiro
Low-level laser therapy (LLLT) has been suggested as a resource capable of increasing resistance to fatigue and enhancing muscle performance through its metabolic and photochemical effects. This study evaluated the immediate effects of the application of LLLT on neuromuscular performance of the plantar ankle flexors in healthy subjects through a fatigue-induced protocol. This is a randomized controlled clinical trial, attended by 60 young and physically active volunteers of both genders. The subjects were randomly assigned into three groups, control, placebo, and laser, and underwent a preliminary evaluation of the isokinetic performance of plantar flexors and electromyographic activity of the soleus muscle to ensure homogeneity between groups...
December 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27632884/prolonged-achilles-tendon-vibration-does-not-alter-the-neuromuscular-performance-of-plantar-flexor-muscles
#18
Thomas Cattagni, Clément Billet, Christophe Cornu, Marc Jubeau
CONTEXT: The prolonged tendon vibration may induce muscle fatigue, as assessed by a decrease in maximal force production. It remains however unknown whether the decrease in muscle strength after prolonged Achilles tendon vibration is related to the vibration frequency. OBJECTIVE: This study aimed to assess the maximal capacity of plantar flexor neuromuscular function before and after prolonged Achilles tendon vibration at low and high frequencies generated using a portable device...
August 24, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27632038/research-association-of-low-amplitude-qrss-with-false-positive-asystole-alarms
#19
Michele M Pelter, Richard Fidler, Xiao Hu
BACKGROUND: Although electrocardiographic monitoring is valuable for continuous surveillance of intensive care unit (ICU) patients, false alarms are common and have been cited as a cause of alarm fatigue. ANSI/AAMI EC12:2002 states that electrocardiograms (ECGs) should not detect a QRS if the waveform is less than 0.15 mV (1.5 mm) for adult patients, in order to avoid mislabeling P waves or baseline noise as QRSs during complete heart block or asystole. However, ECG software algorithms often use more conservative QRS thresholds, which may result in false-positive asystole alarms in patients with low-amplitude QRS complexes...
September 2016: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/27623756/effects-of-plyometric-exercise-training-with-external-weights-on-punching-ability-of-experienced-amateur-boxers
#20
Vidas Bruzas, Sigitas Kamandulis, Tomas Venckunas, Audrius Snieckus, Pranas Mockus
BACKGROUND: During competition, a boxer must continue to deliver high-impact punches despite increasing fatigue. It is unclear whether the effects of plyometric training using external weights are transferred to sport-specific movements such as punching. The aim of the study was to investigate the effects of a 4-week cycle of plyometric training with external weights on punching ability. METHODS: The study involved eight male amateur boxers aged 22.3±2.5 years with at least 7 years of competitive experience...
September 13, 2016: Journal of Sports Medicine and Physical Fitness
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