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https://www.readbyqxmd.com/read/28087436/functional-connectivity-analysis-using-fnirs-in-healthy-subjects-during-prolonged-simulated-driving
#1
Liwei Xu, Bitian Wang, Gongcheng Xu, Wei Wang, Zhian Liu, Zengyong Li
Noninvasive and accurate assessment of driving fatigue in relation to brain activity during long-term driving can contribute to traffic safety and accident prevention. This study evaluated functional connectivity (FC) in relevant brain regions. Synergistic mechanisms in different brain regions were detected by a novel simulator, which combined semi-immersive virtual reality technology and functional near-infrared spectroscopy. Each subject was instructed to complete driving tasks coupled with a mental calculation task...
January 10, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28060906/steady-state-motion-visual-evoked-potential-ssmvep-based-on-equal-luminance-colored-enhancement
#2
Wenqiang Yan, Guanghua Xu, Min Li, Jun Xie, Chengcheng Han, Sicong Zhang, Ailing Luo, Chaoyang Chen
Steady-state visual evoked potential (SSVEP) is one of the typical stimulation paradigms of brain-computer interface (BCI). It has become a research approach to improve the performance of human-computer interaction, because of its advantages including multiple objectives, less recording electrodes for electroencephalogram (EEG) signals, and strong anti-interference capacity. Traditional SSVEP using light flicker stimulation may cause visual fatigue with a consequent reduction of recognition accuracy. To avoid the negative impacts on the brain response caused by prolonged strong visual stimulation for SSVEP, steady-state motion visual evoked potential (SSMVEP) stimulation method was used in this study by an equal-luminance colored ring-shaped checkerboard paradigm...
2017: PloS One
https://www.readbyqxmd.com/read/28044431/abnormal-resting-state-neural-activity-and-connectivity-of-fatigue-in-parkinson-s-disease
#3
Jie-Jin Zhang, Jian Ding, Jun-Yi Li, Min Wang, Yong-Sheng Yuan, Li Zhang, Si-Ming Jiang, Xi-Xi Wang, Lin Zhu, Ke-Zhong Zhang
AIMS: Fatigue is a common burdensome problem in patients with Parkinson's disease (PD), but its pathophysiological mechanisms are poorly understood. This study aimed at investigating the neural substrates of fatigue in patients with PD. METHODS: A total of 17 PD patients with fatigue, 32 PD patients without fatigue, and 25 matched healthy controls were recruited. The 9-item fatigue severity scale (FSS) was used for fatigue screening and severity rating. Resting-state functional magnetic resonance imaging (RS-fMRI) data were obtained from all subjects...
January 3, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/28033533/fatigue-responses-of-the-human-cervical-spine-intervertebral-discs
#4
Narayan Yoganandan, Sagar Umale, Brain Stemper, Bryan Snyder
Numerous studies have been conducted since more than fifty years to understand the behavior of the human lumbar spine under fatigue loading. Applications have been largely driven by low back pain and human body vibration problems. The human neck also sustains fatigue loading in certain type of civilian occupational and military operational activities, and research is very limited in this area. Being a visco-elastic structure, it is important to determine the stress-relaxation properties of the human cervical spine intervertebral discs to enable accurate simulations of these structures in stress-analysis models...
December 15, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28032007/cognition-depression-fatigue-and-quality-of-life-in-primary-sj%C3%A3-gren-s-syndrome-correlations
#5
Belgin Koçer, Mehmet Engin Tezcan, Hale Zeynep Batur, Şeminur Haznedaroğlu, Berna Göker, Ceyla İrkeç, Rümeysa Çetinkaya
OBJECTIVE: The aim of the present study was to investigate the prevalence and pattern of cognitive dysfunction observed in primary Sjögren's syndrome (PSS) and to examine the relationships between cognitive abilities, depression, fatigue, and quality of life. MATERIALS AND METHODS: Thirty-two subjects with PSS were compared with 19 healthy controls on comprehensive neuropsychological, depression, fatigue, health state, and daily-life activities tests. RESULTS: There was low performance in Clock Drawing, COWAT, Paced Auditory Serial Addition Test (PASAT), Colorless Word Reading (Stroop1) and Recognizing Colors (Stroop2) Patterns of STROOP test, SDLT, Auditory-Verbal Learning Test (AVLT), immediate and long-term verbal memory, Benton Judgment of Line Orientation Test (BJLOT), and in all the patterns of RCFT in PSS patients compared to the healthy control group (p < ...
December 2016: Brain and Behavior
https://www.readbyqxmd.com/read/28010813/changes-in-systolic-arterial-pressure-variability-are-associated-with-the-decreased-aerobic-performance-of-rats-subjected-to-physical-exercise-in-the-heat
#6
Flávia C Müller-Ribeiro, Samuel P Wanner, Weslley H M Santos, Milene R Malheiros-Lima, Ivana A T Fonseca, Cândido C Coimbra, Washington Pires
Enhanced cardiovascular strain is one of the factors that explains degraded aerobic capacity in hot environments. The cardiovascular system is regulated by the autonomic nervous system, whose activity can be indirectly evaluated by analyzing heart rate variability (HRV) and systolic arterial pressure (SAP) variability. However, no study has addressed whether HRV or SAP variability can predict aerobic performance during a single bout of exercise. Therefore, this study aimed to investigate whether there is an association between cardiovascular variability and performance in rats subjected to treadmill running at two ambient temperatures...
January 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/27990242/effect-of-stochastic-modulation-of-inter-pulse-interval-during-stimulated-isokinetic-leg-extension
#7
Efe Anil Aksöz, Marco Laubacher, Stuart Binder-Macleod, Kenneth J Hunt
Recumbent cycling exercise achieved by functional electrical stimulation (FES) of the paralyzed leg muscles is effective for cardiopulmonary and musculoskeletal conditioning after spinal cord injury, but its full potential has not yet been realized. Mechanical power output and efficiency is very low and endurance is limited due to early onset of muscle fatigue. The aim of this work was to compare stochastic modulation of the inter-pulse interval (IPI) to constant-frequency stimulation during an isokinetic leg extension task similar to FES-cycling...
June 13, 2016: European Journal of Translational Myology
https://www.readbyqxmd.com/read/27939350/quantifying-the-history-dependency-of-muscle-recovery-from-a-fatiguing-intermittent-task
#8
Ehsan Rashedi, Maury A Nussbaum
Muscle fatigue and recovery are complex processes influencing muscle force generation capacity. While fatigue reduces this capacity, recovery acts to restore the unfatigued muscle state. Many factors can potentially affect muscle recovery, and among these may be a task dependency of recovery following an exercise. However, little has been reported regarding the history dependency of recovery after fatiguing contractions. We examined the dependency of muscle recovery subsequent to four different histories of fatiguing muscle contractions, imposed using two cycle times (30 and 60s) during low to moderate levels (15% and 25% of maximum voluntary contraction (MVC)) of intermittent static exertions involving index finger abduction...
January 25, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/27928216/low-frequency-fatigue-assessed-as-double-to-single-twitch-ratio-after-two-bouts-of-eccentric-exercise-of-the-elbow-flexors
#9
Damian Janecki, Anna Jaskólska, Jarosław Marusiak, Artur Jaskólski
The aim of this study was to assess low-frequency fatigue as a double to single twitch ratio after repeated eccentric exercise of the elbow flexors. Maximal isometric torque, single and double twitch responses and low-frequency fatigue were assessed on the elbow flexors in 16 untrained male volunteers before, immediately after, 24 and 48 hours following two bouts of eccentric exercise consisted of 30 repetitions of lowering a dumbbell adjusted to ~75% of each individual's maximal isometric torque. Maximal isometric torque and electrically evoked responses decreased significantly in all measurements after the first bout of eccentric exercise (p < 0...
December 2016: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/27919265/fatigue-in-patients-with-juvenile-idiopathic-arthritis-relationship-to-perceived-health-physical-health-self-efficacy-and-participation
#10
Wineke Armbrust, Otto H T M Lelieveld, Jolanda Tuinstra, Nico M Wulffraat, G J F Joyce Bos, Jeannette Cappon, Marion A J van Rossum, Pieter J J Sauer, Mariët Hagedoorn
BACKGROUND: Fatigue is common in patients with JIA and affects daily life negatively. We assessed the presence and severity of fatigue in patients with JIA, including factors presumed associated with fatigue (e.g., disease activity, disability, pain, physical activity, exercise capacity, and self-efficacy), and whether fatigue is related to participation in physical education classes, school attendance, and sports frequency. METHODS: The current study used baseline data of 80 patients with JIA (age 8-13) who participated in an intervention aimed at promoting physical activity...
December 6, 2016: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/27918667/neuromuscular-fatigue-aetiology-after-repeated-sprints-depends-on-exercise-modality
#11
Katja Tomazin, Jean-Benoit Morin, Guillaume Y Millet
PURPOSE: The aim of the study was to compare neuromuscular fatigue induced by repeated sprint running vs cycling. METHODS: Eleven active male participants performed two repeated maximal sprint protocol (5×6 s, 24-s rest periods, 4 sets, 3-min between sets), one in running (treadmill) and one in cycling (cycle ergometer). Neuromuscular function, evaluated before (PRE), 30 s after the first (S1), the second (S2), and the last set (LAST), and 5 min after the last set (POST5), consisted in determining knee extensors maximal voluntary torque (MVC), voluntary activation (VA), single twitch (Tw), high- (Db100) and low- (Db10) frequency torque, and maximal muscle compound action potential (M-wave) amplitude and duration of vastus lateralis...
December 5, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27900297/effects-of-lymphatic-drainage-and-local-cryo-exposition-regeneration-after-high-intensive-exercises
#12
Michael Behringer, Diana Jedlicka, Molly McCourt, Matthias Ring, Joachim Mester
BACKGROUND: Recovery from exercise and competition is important in sports medicine, particularly when rest periods are short. The objective is to determine the efficacy of cryo exposition (CRY) and manual lymphatic drainage (MLD) to hasten short term recovery of muscle performance after eccentric contractions. METHODS: In a randomized controlled trial, 30 healthy sport students (21 males, 9 females; age: 25.7±2.8 years) performed 4×20 eccentric contractions of knee extensors, followed by 30 min MLD, CRY, or rest (RST) under controlled laboratory environment...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27869319/the-ca-2-sensitizer-ck-2066260-increases-myofibrillar-ca-2-sensitivity-and-submaximal-force-selectively-in-fast-skeletal-muscle
#13
Darren T Hwee, Arthur J Cheng, James J Hartman, Aaron C Hinken, Ken Lee, Nickie Durham, Alan J Russell, Fady I Malik, Håkan Westerblad, Jeffrey R Jasper
Skeletal muscle dysfunction occurs in many diseases and can lead to muscle weakness and premature muscle fatigue. Here we show that the fast skeletal troponin activator, CK-2066260, counteracts muscle weakness by increasing troponin Ca(2+) affinity, thereby increasing myofibrillar Ca(2+) sensitivity. Exposure to CK-2066260 resulted in a concentration-dependent increase in the Ca(2+) sensitivity of ATPase activity in isolated myofibrils and reconstituted hybrid sarcomeres containing fast skeletal muscle troponin C...
November 21, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27822928/factors-contributing-to-discordance-between-the-2011-acr-eular-criteria-and-physician-clinical-judgment-for-the-identification-of-remission-in-patients-with-rheumatoid-arthritis
#14
Yoon Kyoung Sung, Soo Kyung Cho, Dam Kim, Bo Young Yoon, Chan Bum Choi, Hoon Suk Cha, Jung Yoon Choe, Won Tae Chung, Seung Jae Hong, Jae Bum Jun, Young Mo Kang, Jinseok Kim, Tae Hwan Kim, Tae Jong Kim, Eunmi Koh, Choong Ki Lee, Jisoo Lee, Shin Seok Lee, Sung Won Lee, Hye Soon Lee, Yeon Ah Lee, Sung Hoon Park, Dae Hyun Yoo, Wan Hee Yoo, Sang Cheol Bae
Remission is a primary end point of in clinical practice and trials of treatments for rheumatoid arthritis (RA). The 2011 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) remission criteria were developed to provide a consensus definition of remission. This study aimed to assess the concordance between the new remission criteria and the physician's clinical judgment of remission and also to identify factors that affect the discordance between these two approaches. A total of 3,209 patients with RA were included from the KORean Observational Study Network for Arthritis (KORONA) database...
December 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27810980/wavelet-coherence-analysis-of-cerebral-oxygenation-signals-measured-by-near-infrared-spectroscopy-in-sailors-an-exploratory-experimental-study
#15
Lingguo Bu, Jianfeng Li, Fangyi Li, Heshan Liu, Zengyong Li
OBJECTIVE: The objective of this study was to assess the effects of long-term offshore work on cerebral oxygenation oscillations in sailors based on the wavelet phase coherence (WPCO) of near-infrared spectroscopy (NIRS) signals. METHODS: The fatigue severity scale (FSS) was first applied to assess the fatigue level of sailors and age-matched controls. Continuous recordings of NIRS signals were then obtained from the prefrontal lobes in 30 healthy sailors and 30 age-matched controls during the resting state...
November 3, 2016: BMJ Open
https://www.readbyqxmd.com/read/27798178/differential-expression-of-munc13-2-produces-unique-synaptic-phenotypes-in-the-basolateral-amygdala-of-c57bl-6j-and-dba-2j-mice
#16
Dominic A Gioia, Nancy J Alexander, Brian A McCool
: C57BL/6J (B6) and DBA/2J (D2) mice are well known to differentially express a number of behavioral phenotypes, including anxiety-like behavior, fear conditioning, and drug self-administration. However, the cellular mechanisms contributing to these differences remain unclear. Given the basolateral amygdala (BLA) contributes to these behaviors, we characterized strain-dependent differences in presynaptic and postsynaptic function in BLA neurons by integrating electrophysiological, biochemical, and genetic approaches to identify specific molecular mechanisms...
October 26, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27798141/fatigue-in-rapsyn-deficient-zebrafish-reflects-defective-transmitter-release
#17
Hua Wen, Jeffrey Michael Hubbard, Wei-Chun Wang, Paul Brehm
: Rapsyn-deficient myasthenic syndrome is characterized by a weakness in voluntary muscle contraction, a direct consequence of greatly reduced synaptic responses that result from poorly clustered acetylcholine receptors. As with other myasthenic syndromes, the general muscle weakness is also accompanied by use-dependent fatigue. Here, we used paired motor neuron target muscle patch-clamp recordings from a rapsyn-deficient mutant line of zebrafish to explore for the first time the mechanisms causal to fatigue...
October 19, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27772773/predictors-of-health-related-quality-of-life-in-people-with-amyotrophic-lateral-sclerosis
#18
Petter Sandstedt, Sverker Johansson, Charlotte Ytterberg, Caroline Ingre, Lotta Widén Holmqvist, Marie Kierkegaard
BACKGROUND: Knowledge of factors influencing health-related quality of life (HRQL) in people with amyotrophic lateral sclerosis (ALS) is important because some factors might be amenable to intervention. OBJECTIVES: The aim was to describe and explore the effects of disease severity, fatigue, anxiety, depression, frequency of social and lifestyle activities, coping capacity and mechanical ventilator use on HRQL in people with ALS. METHODS: Sixty people with ALS were enrolled in this cross-sectional study...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27771595/using-a-chewing-simulator-for-fatigue-testing-of-metal-ceramic-crowns
#19
S D Heintze, A Eser, D Monreal, V Rousson
OBJECTIVE: Dynamic loading is a more important predictor for the clinical longevity of ceramic crowns than static loading. However, dynamic loading machines are costly and mostly have only one test station. The SD Mechatronik Chewing Simulator (formerly Willytec) may be a cost-effective alternative to evaluate the fatigue resistance of metal ceramic crowns. METHOD: Four metal ceramic materials were tested on lower first molar crowns: GC InitiaI, Creation (Willy Geller), IPS InLine (Ivoclar Vivadent) and the new low-fusion IPS Style Ceram (Ivoclar Vivadent)...
January 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27766128/the-effect-of-skinfold-on-the-assessment-of-the-mean-power-frequency-at-the-fatigue-threshold
#20
Alyssandra N Baniqued, Jorge M Zuniga, Thomas C Strunc, Katie M Keenan, Agrini K Boken, Jeffrey J Anderson
The purpose of this study was to determine if the amount of subcutaneous tissue over the quadriceps affects the assessment of mean power frequency at the fatigue threshold (MPFFT). It was hypothesized that greater skinfold values will result in lower power outputs associated to the MPFFT. Fourteen adults (Mean ± SD age = 20.7 ± 0.99; body weight = 72.8 ± 12.6 kg) performed an incremental cycle ergometry test to exhaustion while surface electromyographic (EMG) signals were measured from the vastus lateralis...
2016: International Journal of Exercise Science
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