keyword
https://read.qxmd.com/read/38422168/identifying-metabolic-adaptations-characteristic-of-cardiotoxicity-using-paired-transcriptomics-and-metabolomics-data-integrated-with-a-computational-model-of-heart-metabolism
#21
JOURNAL ARTICLE
Bonnie V Dougherty, Connor J Moore, Kristopher D Rawls, Matthew L Jenior, Bryan Chun, Sarbajeet Nagdas, Jeffrey J Saucerman, Glynis L Kolling, Anders Wallqvist, Jason A Papin
Improvements in the diagnosis and treatment of cancer have revealed long-term side effects of chemotherapeutics, particularly cardiotoxicity. Here, we present paired transcriptomics and metabolomics data characterizing in vitro cardiotoxicity to three compounds: 5-fluorouracil, acetaminophen, and doxorubicin. Standard gene enrichment and metabolomics approaches identify some commonly affected pathways and metabolites but are not able to readily identify metabolic adaptations in response to cardiotoxicity. The paired data was integrated with a genome-scale metabolic network reconstruction of the heart to identify shifted metabolic functions, unique metabolic reactions, and changes in flux in metabolic reactions in response to these compounds...
February 29, 2024: PLoS Computational Biology
https://read.qxmd.com/read/38419006/interaction-models-matter-an-efficient-flexible-computational-framework-for-model-specific-investigation-of-epistasis
#22
JOURNAL ARTICLE
Sandra Batista, Vered Senderovich Madar, Philip J Freda, Priyanka Bhandary, Attri Ghosh, Nicholas Matsumoto, Apurva S Chitre, Abraham A Palmer, Jason H Moore
PURPOSE: Epistasis, the interaction between two or more genes, is integral to the study of genetics and is present throughout nature. Yet, it is seldom fully explored as most approaches primarily focus on single-locus effects, partly because analyzing all pairwise and higher-order interactions requires significant computational resources. Furthermore, existing methods for epistasis detection only consider a Cartesian (multiplicative) model for interaction terms. This is likely limiting as epistatic interactions can evolve to produce varied relationships between genetic loci, some complex and not linearly separable...
February 28, 2024: BioData Mining
https://read.qxmd.com/read/38412228/general-versus-nongeneral-anesthesia-for-middle-meningeal-artery-embolization-for-chronic-subdural-hematomas-multicenter-propensity-score-matched-study
#23
JOURNAL ARTICLE
Mohamed M Salem, Georgios S Sioutas, Jane Khalife, Okkes Kuybu, Kate Caroll, Alex Nguyen Hoang, Ammad A Baig, Mira Salih, Mirhojjat Khorasanizadeh, Cordell Baker, Aldo A Mendez, Gustavo Cortez, Zachary A Abecassis, Juan F Ruiz Rodriguez, Jason M Davies, Sandra Narayanan, C Michael Cawley, Howard A Riina, Justin M Moore, Alejandro M Spiotta, Alexander A Khalessi, Brian M Howard, Ricardo Hanel, Omar Tanweer, Daniel A Tonetti, Adnan H Siddiqui, Michael J Lang, Elad I Levy, Peter Kan, Tudor Jovin, Ramesh Grandhi, Visish M Srinivasan, Christopher S Ogilvy, Bradley A Gross, Brian T Jankowitz, Ajith J Thomas, Michael R Levitt, Jan-Karl Burkhardt
BACKGROUND AND OBJECTIVES: The choice of anesthesia type (general anesthesia [GA] vs nongeneral anesthesia [non-GA]) in middle meningeal artery embolization (MMAE) procedures for chronic subdural hematomas (cSDH) differs between institutions and left to care team discretion given lack of standard guidelines. We compare the outcomes of GA vs non-GA in MMAE. METHODS: Consecutive patients receiving MMAE for cSDH at 14 North American centers (2018-2023) were included...
February 27, 2024: Neurosurgery
https://read.qxmd.com/read/38352349/focused-ultrasound-blood-brain-barrier-opening-arrests-the-growth-and-formation-of-cerebral-cavernous-malformations
#24
Delaney G Fisher, Khadijeh A Sharifi, Ishaan M Shah, Catherine M Gorick, Victoria R Breza, Anna C Debski, Matthew R Hoch, Tanya Cruz, Joshua D Samuels, Jason P Sheehan, David Schlesinger, David Moore, John R Lukens, G Wilson Miller, Petr Tvrdik, Richard J Price
BACKGROUND: Cerebral cavernous malformations (CCM) are vascular lesions within the central nervous system, consisting of dilated and hemorrhage-prone capillaries. CCMs can cause debilitating neurological symptoms, and surgical excision or stereotactic radiosurgery are the only current treatment options. Meanwhile, transient blood-brain barrier opening (BBBO) with focused ultrasound (FUS) and microbubbles is now understood to exert potentially beneficial bioeffects, such as stimulation of neurogenesis and clearance of amyloid-β...
February 4, 2024: bioRxiv
https://read.qxmd.com/read/38347552/molecular-guided-therapy-for-the-treatment-of-patients-with-relapsed-and-refractory-childhood-cancers-a-beat-childhood-cancer-research-consortium-trial
#25
JOURNAL ARTICLE
Giselle L Saulnier Sholler, Genevieve Bergendahl, Elizabeth C Lewis, Jacqueline Kraveka, William Ferguson, Abhinav B Nagulapally, Karl Dykema, Valerie I Brown, Michael S Isakoff, Joseph Junewick, Deanna Mitchell, Jawhar Rawwas, William Roberts, Don Eslin, Javier Oesterheld, Randal K Wada, Devang Pastakia, Virginia Harrod, Kevin Ginn, Raya Saab, Kevin Bielamowicz, Jason Glover, Eugenia Chang, Gina K Hanna, Daniel Enriquez, Tyler Izatt, Rebecca F Halperin, Abigail Moore, Sara A Byron, William P D Hendricks, Jeffrey M Trent
BACKGROUND: Children with relapsed central nervous system (CNS tumors), neuroblastoma, sarcomas, and other rare solid tumors face poor outcomes. This prospective clinical trial examined the feasibility of combining genomic and transcriptomic profiling of tumor samples with a molecular tumor board (MTB) approach to make real‑time treatment decisions for children with relapsed/refractory solid tumors. METHODS: Subjects were divided into three strata: stratum 1-relapsed/refractory neuroblastoma; stratum 2-relapsed/refractory CNS tumors; and stratum 3-relapsed/refractory rare solid tumors...
February 12, 2024: Genome Medicine
https://read.qxmd.com/read/38346970/the-bii4africa-dataset-of-faunal-and-floral-population-intactness-estimates-across-africa-s-major-land-uses
#26
JOURNAL ARTICLE
Hayley S Clements, Emmanuel Do Linh San, Gareth Hempson, Birthe Linden, Bryan Maritz, Ara Monadjem, Chevonne Reynolds, Frances Siebert, Nicola Stevens, Reinette Biggs, Alta De Vos, Ryan Blanchard, Matthew Child, Karen J Esler, Maike Hamann, Ty Loft, Belinda Reyers, Odirilwe Selomane, Andrew L Skowno, Tshegofatso Tshoke, Diarrassouba Abdoulaye, Thierry Aebischer, Jesús Aguirre-Gutiérrez, Graham J Alexander, Abdullahi H Ali, David G Allan, Esther E Amoako, Samuel Angedakin, Edward Aruna, Nico L Avenant, Gabriel Badjedjea, Adama Bakayoko, Abraham Bamba-Kaya, Michael F Bates, Paul J J Bates, Steven R Belmain, Emily Bennitt, James Bradley, Chris A Brewster, Michael B Brown, Michelle Brown, Josef Bryja, Thomas M Butynski, Filipe Carvalho, Alan Channing, Colin A Chapman, Callan Cohen, Marina Cords, Jennifer D Cramer, Nadine Cronk, Pamela M K Cunneyworth, Fredrik Dalerum, Emmanuel Danquah, Harriet T Davies-Mostert, Andrew D de Blocq, Yvonne A De Jong, Terrence C Demos, Christiane Denys, Chabi A M S Djagoun, Thomas M Doherty-Bone, Marine Drouilly, Johan T du Toit, David A Ehlers Smith, Yvette C Ehlers Smith, Seth J Eiseb, Peter J Fashing, Adam W Ferguson, José M Fernández-García, Manfred Finckh, Claude Fischer, Edson Gandiwa, Philippe Gaubert, Jerome Y Gaugris, Dalton J Gibbs, Jason S Gilchrist, Jose M Gil-Sánchez, Anthony N Githitho, Peter S Goodman, Laurent Granjon, J Paul Grobler, Bonginkosi C Gumbi, Vaclav Gvozdik, James Harvey, Morgan Hauptfleisch, Firas Hayder, Emmanuel M Hema, Marna Herbst, Mariano Houngbédji, Brian J Huntley, Rainer Hutterer, Samuel T Ivande, Kate Jackson, Gregory F M Jongsma, Javier Juste, Blaise Kadjo, Prince K Kaleme, Edwin Kamugisha, Beth A Kaplin, Humphrey N Kato, Christian Kiffner, Duncan M Kimuyu, Robert M Kityo, N'goran G Kouamé, Marcel Kouete T, Aliza le Roux, Alan T K Lee, Mervyn C Lötter, Anne Mette Lykke, Duncan N MacFadyen, Gacheru P Macharia, Zimkitha J K Madikiza, Themb'alilahlwa A M Mahlaba, David Mallon, Mnqobi L Mamba, Claude Mande, Rob A Marchant, Robin A Maritz, Wanda Markotter, Trevor McIntyre, John Measey, Addisu Mekonnen, Paulina Meller, Haemish I Melville, Kevin Z Mganga, Michael G L Mills, Liaan Minnie, Alain Didier Missoup, Abubakr Mohammad, Nancy N Moinde, Bakwo Fils E Moise, Pedro Monterroso, Jennifer F Moore, Simon Musila, Sedjro Gilles A Nago, Maganizo W Namoto, Fatimata Niang, Violaine Nicolas, Jerry B Nkenku, Evans E Nkrumah, Gonwouo L Nono, Mulavwa M Norbert, Katarzyna Nowak, Benneth C Obitte, Arnold D Okoni-Williams, Jonathan Onongo, M Justin O'Riain, Samuel T Osinubi, Daniel M Parker, Francesca Parrini, Mike J S Peel, Johannes Penner, Darren W Pietersen, Andrew J Plumptre, Damian W Ponsonby, Stefan Porembski, R John Power, Frans G T Radloff, Ramugondo V Rambau, Tharmalingam Ramesh, Leigh R Richards, Mark-Oliver Rödel, Dominic P Rollinson, Francesco Rovero, Mostafa A Saleh, Ute Schmiedel, M Corrie Schoeman, Paul Scholte, Thomas L Serfass, Julie Teresa Shapiro, Sidney Shema, Stefan J Siebert, Jasper A Slingsby, Alexander Sliwa, Hanneline A Smit-Robinson, Etotepe A Sogbohossou, Michael J Somers, Stephen Spawls, Jarryd P Streicher, Lourens Swanepoel, Iroro Tanshi, Peter J Taylor, William A Taylor, Mariska Te Beest, Paul T Telfer, Dave I Thompson, Elie Tobi, Krystal A Tolley, Andrew A Turner, Wayne Twine, Victor Van Cakenberghe, Frederik Van de Perre, Helga van der Merwe, Chris J G van Niekerk, Pieter C V van Wyk, Jan A Venter, Luke Verburgt, Geraldine Veron, Susanne Vetter, Maria S Vorontsova, Thomas C Wagner, Paul W Webala, Natalie Weber, Sina M Weier, Paula A White, Melissa A Whitecross, Benjamin J Wigley, Frank J Willems, Christiaan W Winterbach, Galena M Woodhouse
Sub-Saharan Africa is under-represented in global biodiversity datasets, particularly regarding the impact of land use on species' population abundances. Drawing on recent advances in expert elicitation to ensure data consistency, 200 experts were convened using a modified-Delphi process to estimate 'intactness scores': the remaining proportion of an 'intact' reference population of a species group in a particular land use, on a scale from 0 (no remaining individuals) to 1 (same abundance as the reference) and, in rare cases, to 2 (populations that thrive in human-modified landscapes)...
February 12, 2024: Scientific Data
https://read.qxmd.com/read/38324244/artificial-intelligence-and-technology-collaboratories-innovating-aging-research-and-alzheimer-s-care
#27
JOURNAL ARTICLE
Peter Abadir, Esther Oh, Rama Chellappa, Niteesh Choudhry, George Demiris, Deepak Ganesan, Jason Karlawish, Benjamin Marlin, Rose M Li, Najim Dehak, Alicia Arbaje, Mathias Unberath, Thomas Cudjoe, Christopher Chute, Jason H Moore, Phillip Phan, Quincy Samus, Nancy L Schoenborn, Alexis Battle, Jeremy D Walston
This perspective outlines the Artificial Intelligence and Technology Collaboratories (AITC) at Johns Hopkins University, University of Pennsylvania, and University of Massachusetts, highlighting their roles in developing AI-based technologies for older adult care, particularly targeting Alzheimer's disease (AD). These National Institute on Aging (NIA) centers foster collaboration among clinicians, gerontologists, ethicists, business professionals, and engineers to create AI solutions. Key activities include identifying technology needs, stakeholder engagement, training, mentoring, data integration, and navigating ethical challenges...
February 7, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://read.qxmd.com/read/38297180/prescribing-practices-of-inhaled-corticosteroids-for-premature-infants-in-the-neonatal-intensive-care-unit
#28
JOURNAL ARTICLE
Monica Tang, Anna Ibrahim, Christopher Laughon, Kaila Moore, Angibel Tejada, Dean Tran, Ryan Kilpatrick, Rachel G Greenberg, Christoph P Hornik, Kanecia Zimmerman, Matthew M Laughon, Reese H Clark, Jason E Lang
OBJECTIVE: Despite limited safety and efficacy data, inhaled corticosteroids (ICS) are prescribed to premature infants in the neonatal intensive care unit (NICU). We examined contemporary use and risk factors for ICS use in the NICU. STUDY DESIGN: Infants <33 weeks gestational age and <1500 gm birth weight discharged from Pediatrix Medical Group NICUs between 2010 and 2020 were included. We evaluated the association between ICS prescription and clinical characteristics using univariable and multivariable logistic regression...
January 31, 2024: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/38278722/clinical-outcomes-of-standardized-central-venous-catheterization-simulation-training-a-comparative-analysis
#29
JOURNAL ARTICLE
Jessica M Gonzalez-Vargas, Elizabeth Sinz, Jason Z Moore, Scarlett R Miller
OBJECTIVE: A standardized ultrasound-guided Internal Jugular Central Venous Catheterization (US-IJCVC) using online- and simulation-based training was first designed and then large-scale deployed at a teaching hospital institution to improve CVC surgical education. To understand the impact that the standardized training might have on patient complications, this study focuses on identifying the impact of the integration of an iteratively designed US-IJCVC training on clinical complications at a teaching hospital...
January 25, 2024: Journal of Surgical Education
https://read.qxmd.com/read/38271507/machine-learning-predicts-which-rivers-streams-and-wetlands-the-clean-water-act-regulates
#30
JOURNAL ARTICLE
Simon Greenhill, Hannah Druckenmiller, Sherrie Wang, David A Keiser, Manuela Girotto, Jason K Moore, Nobuhiro Yamaguchi, Alberto Todeschini, Joseph S Shapiro
We assess which waters the Clean Water Act protects and how Supreme Court and White House rules change this regulation. We train a deep learning model using aerial imagery and geophysical data to predict 150,000 jurisdictional determinations from the Army Corps of Engineers, each deciding regulation for one water resource. Under a 2006 Supreme Court ruling, the Clean Water Act protects two-thirds of US streams and more than half of wetlands; under a 2020 White House rule, it protects less than half of streams and a fourth of wetlands, implying deregulation of 690,000 stream miles, 35 million wetland acres, and 30% of waters around drinking-water sources...
January 26, 2024: Science
https://read.qxmd.com/read/38270128/prevalence-of-sars-cov-2-infection-among-children-and-adults-in-15-us-communities-2021-1
#31
JOURNAL ARTICLE
Jessica Justman, Timothy Skalland, Ayana Moore, Christopher I Amos, Mark A Marzinke, Sahar Z Zangeneh, Colleen F Kelley, Rebecca Singer, Stockton Mayer, Yael Hirsch-Moverman, Susanne Doblecki-Lewis, David Metzger, Elizabeth Barranco, Ken Ho, Ernesto T A Marques, Margaret Powers-Fletcher, Patricia J Kissinger, Jason E Farley, Carrie Knowlton, Magdalena E Sobieszczyk, Shobha Swaminathan, Domonique Reed, Jean De Dieu Tapsoba, Lynda Emel, Ian Bell, Krista Yuhas, Leah Schrumpf, Laura Mkumba, Jontraye Davis, Jonathan Lucas, Estelle Piwowar-Manning, Shahnaz Ahmed
During January-August 2021, the Community Prevalence of SARS-CoV-2 Study used time/location sampling to recruit a cross-sectional, population-based cohort to estimate SARS-CoV-2 seroprevalence and nasal swab sample PCR positivity across 15 US communities. Survey-weighted estimates of SARS-CoV-2 infection and vaccine willingness among participants at each site were compared within demographic groups by using linear regression models with inverse variance weighting. Among 22,284 persons >2 months of age and older, median prevalence of infection (prior, active, or both) was 12...
February 2024: Emerging Infectious Diseases
https://read.qxmd.com/read/38260403/mixwas-an-efficient-distributed-algorithm-for-mixed-outcomes-genome-wide-association-studies
#32
Ruowang Li, Luke Benz, Rui Duan, Joshua C Denny, Hakon Hakonarson, Jonathan D Mosley, Jordan W Smoller, Wei-Qi Wei, Marylyn D Ritchie, Jason H Moore, Yong Chen
Genome-wide association studies (GWAS) have been instrumental in identifying genetic associations for various diseases and traits. However, uncovering genetic underpinnings among traits beyond univariate phenotype associations remains a challenge. Multi-phenotype associations (MPA), or genetic pleiotropy, offer important insights into shared genes and pathways among traits, enhancing our understanding of genetic architectures of complex diseases. GWAS of biobank-linked electronic health record (EHR) data are increasingly being utilized to identify MPA among various traits and diseases...
January 10, 2024: medRxiv
https://read.qxmd.com/read/38253803/the-molecular-twin-artificial-intelligence-platform-integrates-multi-omic-data-to-predict-outcomes-for-pancreatic-adenocarcinoma-patients
#33
JOURNAL ARTICLE
Arsen Osipov, Ognjen Nikolic, Arkadiusz Gertych, Sarah Parker, Andrew Hendifar, Pranav Singh, Darya Filippova, Grant Dagliyan, Cristina R Ferrone, Lei Zheng, Jason H Moore, Warren Tourtellotte, Jennifer E Van Eyk, Dan Theodorescu
Contemporary analyses focused on a limited number of clinical and molecular biomarkers have been unable to accurately predict clinical outcomes in pancreatic ductal adenocarcinoma. Here we describe a precision medicine platform known as the Molecular Twin consisting of advanced machine-learning models and use it to analyze a dataset of 6,363 clinical and multi-omic molecular features from patients with resected pancreatic ductal adenocarcinoma to accurately predict disease survival (DS). We show that a full multi-omic model predicts DS with the highest accuracy and that plasma protein is the top single-omic predictor of DS...
January 22, 2024: Nature Cancer
https://read.qxmd.com/read/38249839/toward-a-common-standard-for-data-and-specimen-provenance-in-life-sciences
#34
JOURNAL ARTICLE
Rudolf Wittner, Petr Holub, Cecilia Mascia, Francesca Frexia, Heimo Müller, Markus Plass, Clare Allocca, Fay Betsou, Tony Burdett, Ibon Cancio, Adriane Chapman, Martin Chapman, Mélanie Courtot, Vasa Curcin, Johann Eder, Mark Elliot, Katrina Exter, Carole Goble, Martin Golebiewski, Bron Kisler, Andreas Kremer, Simone Leo, Sheng Lin-Gibson, Anna Marsano, Marco Mattavelli, Josh Moore, Hiroki Nakae, Isabelle Perseil, Ayat Salman, James Sluka, Stian Soiland-Reyes, Caterina Strambio-De-Castillia, Michael Sussman, Jason R Swedlow, Kurt Zatloukal, Jörg Geiger
Open and practical exchange, dissemination, and reuse of specimens and data have become a fundamental requirement for life sciences research. The quality of the data obtained and thus the findings and knowledge derived is thus significantly influenced by the quality of the samples, the experimental methods, and the data analysis. Therefore, a comprehensive and precise documentation of the pre-analytical conditions, the analytical procedures, and the data processing are essential to be able to assess the validity of the research results...
January 2024: Learning Health Systems
https://read.qxmd.com/read/38234779/a-dynamic-subset-of-network-interactions-underlies-tuning-to-natural-movements-in-marmoset-sensorimotor-cortex
#35
Nicholas Hatsopoulos, Dalton Moore, Jason MacLean, Jeffrey Walker
Mechanisms of computation in sensorimotor cortex must be flexible and robust to support skilled motor behavior. Patterns of neuronal coactivity emerge as a result of computational processes. Pairwise spike-time statistical relationships, across the population, can be summarized as a functional network (FN) which retains single-unit properties. We record populations of single-unit neural activity in forelimb sensorimotor cortex during prey-capture and spontaneous behavior and use an encoding model incorporating kinematic trajectories and network features to predict single-unit activity during forelimb movements...
December 27, 2023: Research Square
https://read.qxmd.com/read/38232376/laser-induced-thermal-decomposition-of-uranium-coordination-compounds-with-non-oxidic-ligands-to-produce-nitride-and-carbide-materials
#36
JOURNAL ARTICLE
Maryline G Ferrier, Bradley C Childs, Chinthaka M Silva, Michelle M Greenough, Emily E Moore, Karla A Erickson, Marisa J Monreal, Christopher A Colla, Maxwell A T Marple, Logan D Winston, Janae N Burks, Aiden A Martin, Jason R Jeffries, Kiel S Holliday
The production of ceramics from uranium coordination compounds can be achieved through thermal processing if an excess amount of the desired atoms (i.e., C or N), or reactive gaseous products (e.g., methane or nitrogen oxide) is made available to the reactive uranium metal core via decomposition/fragmentation of the surrounding ligand groups. Here, computational thermodynamic approaches were utilized to identify the temperatures necessary to produce uranium metal from some starting compounds─UI4 (TMEDA)2 , UCl4 (TMEDA)2 , UCl3 (pyridine) x , and UI3 (pyridine)4 ...
January 17, 2024: Inorganic Chemistry
https://read.qxmd.com/read/38227445/adverse-childhood-experiences-cognitive-functioning-depression-and-anxiety-in-adulthood
#37
JOURNAL ARTICLE
Hanaan Bing-Canar, Jane K Stocks, Humza Khan, Andrew A Rauch, Maximillian A Obolsky, Franchezka Lapitan-Moore, Matthew S Phillips, Jason R Soble, Neil H Pliskin, Woojin Song, Zachary J Resch
BACKGROUND: Evidence suggests that adverse childhood experiences (ACEs) predict cognitive dysfunction, possibly through direct (e.g., brain structure/function changes) and indirect (e.g., increased psychopathology risk) pathways. However, extant studies have focused on young and older adults, with limited understanding of how ACEs affect cognitive health in midadulthood. OBJECTIVE: This study compared psychiatric and cognitive differences between adults at high- and low-risk of adverse health outcomes based on the ACE risk classification scheme...
January 15, 2024: Psychological Trauma: Theory, Research, Practice and Policy
https://read.qxmd.com/read/38220743/balclutha-jafara-hemiptera-cicadellidae-integrative-identification-of-a-species-introduced-in-the-western-hemisphere-and-notes-on-other-balclutha
#38
JOURNAL ARTICLE
James N Zahniser, Susan E Halbert, Matthew R Moore, Jason L Mottern, Julien M Beuzelin
Leafhopper specimens of the genus Balclutha Kirkaldy, found in southern Florida (Palm Beach and Collier Counties), United States, beginning in 2020, and in shipments of plant products originating from Colombia and entering the United States beginning in 2019, are identified as B. jafara Webb. This species was previously known only from the Seychelles and Aldabra Islands, which are parts of the Seychelles archipelago in the Indian Ocean east of mainland Africa. Identifications were made by comparison with type specimens, both morphologically and through molecular analysis...
November 3, 2023: Zootaxa
https://read.qxmd.com/read/38200314/consistent-patterns-of-common-species-across-tropical-tree-communities
#39
JOURNAL ARTICLE
Declan L M Cooper, Simon L Lewis, Martin J P Sullivan, Paulo I Prado, Hans Ter Steege, Nicolas Barbier, Ferry Slik, Bonaventure Sonké, Corneille E N Ewango, Stephen Adu-Bredu, Kofi Affum-Baffoe, Daniel P P de Aguiar, Manuel Augusto Ahuite Reategui, Shin-Ichiro Aiba, Bianca Weiss Albuquerque, Francisca Dionízia de Almeida Matos, Alfonso Alonso, Christian A Amani, Dário Dantas do Amaral, Iêda Leão do Amaral, Ana Andrade, Ires Paula de Andrade Miranda, Ilondea B Angoboy, Alejandro Araujo-Murakami, Nicolás Castaño Arboleda, Luzmila Arroyo, Peter Ashton, Gerardo A Aymard C, Cláudia Baider, Timothy R Baker, Michael Philippe Bessike Balinga, Henrik Balslev, Lindsay F Banin, Olaf S Bánki, Chris Baraloto, Edelcilio Marques Barbosa, Flávia Rodrigues Barbosa, Jos Barlow, Jean-Francois Bastin, Hans Beeckman, Serge Begne, Natacha Nssi Bengone, Erika Berenguer, Nicholas Berry, Robert Bitariho, Pascal Boeckx, Jan Bogaert, Bernard Bonyoma, Patrick Boundja, Nils Bourland, Faustin Boyemba Bosela, Fabian Brambach, Roel Brienen, David F R P Burslem, José Luís Camargo, Wegliane Campelo, Angela Cano, Sasha Cárdenas, Dairon Cárdenas López, Rainiellen de Sá Carpanedo, Yrma Andreina Carrero Márquez, Fernanda Antunes Carvalho, Luisa Fernanda Casas, Hernán Castellanos, Carolina V Castilho, Carlos Cerón, Colin A Chapman, Jerome Chave, Phourin Chhang, Wanlop Chutipong, George B Chuyong, Bruno Barçante Ladvocat Cintra, Connie J Clark, Fernanda Coelho de Souza, James A Comiskey, David A Coomes, Fernando Cornejo Valverde, Diego F Correa, Flávia R C Costa, Janaina Barbosa Pedrosa Costa, Pierre Couteron, Heike Culmsee, Aida Cuni-Sanchez, Francisco Dallmeier, Gabriel Damasco, Gilles Dauby, Nállarett Dávila, Hilda Paulette Dávila Doza, Jose Don T De Alban, Rafael L de Assis, Charles De Canniere, Thales De Haulleville, Marcelo de Jesus Veiga Carim, Layon O Demarchi, Kyle G Dexter, Anthony Di Fiore, Hazimah Haji Mohammad Din, Mathias I Disney, Brice Yannick Djiofack, Marie-Noël K Djuikouo, Tran Van Do, Jean-Louis Doucet, Freddie C Draper, Vincent Droissart, Joost F Duivenvoorden, Julien Engel, Vittoria Estienne, William Farfan-Rios, Sophie Fauset, Kenneth J Feeley, Yuri Oliveira Feitosa, Ted R Feldpausch, Cid Ferreira, Joice Ferreira, Leandro Valle Ferreira, Christine D Fletcher, Bernardo Monteiro Flores, Alusine Fofanah, Ernest G Foli, Émile Fonty, Gabriella M Fredriksson, Alfredo Fuentes, David Galbraith, George Pepe Gallardo Gonzales, Karina Garcia-Cabrera, Roosevelt García-Villacorta, Vitor H F Gomes, Ricardo Zárate Gómez, Therany Gonzales, Rogerio Gribel, Marcelino Carneiro Guedes, Juan Ernesto Guevara, Khalid Rehman Hakeem, Jefferson S Hall, Keith C Hamer, Alan C Hamilton, David J Harris, Rhett D Harrison, Terese B Hart, Andy Hector, Terry W Henkel, John Herbohn, Mireille B N Hockemba, Bruce Hoffman, Milena Holmgren, Euridice N Honorio Coronado, Isau Huamantupa-Chuquimaco, Wannes Hubau, Nobuo Imai, Mariana Victória Irume, Patrick A Jansen, Kathryn J Jeffery, Eliana M Jimenez, Tommaso Jucker, André Braga Junqueira, Michelle Kalamandeen, Narcisse G Kamdem, Kuswata Kartawinata, Emmanuel Kasongo Yakusu, John M Katembo, Elizabeth Kearsley, David Kenfack, Michael Kessler, Thiri Toe Khaing, Timothy J Killeen, Kanehiro Kitayama, Bente Klitgaard, Nicolas Labrière, Yves Laumonier, Susan G W Laurance, William F Laurance, Félix Laurent, Tinh Cong Le, Trai Trong Le, Miguel E Leal, Evlyn Márcia Leão de Moraes Novo, Aurora Levesley, Moses B Libalah, Juan Carlos Licona, Diógenes de Andrade Lima Filho, Jeremy A Lindsell, Aline Lopes, Maria Aparecida Lopes, Jon C Lovett, Richard Lowe, José Rafael Lozada, Xinghui Lu, Nestor K Luambua, Bruno Garcia Luize, Paul Maas, José Leonardo Lima Magalhães, William E Magnusson, Ni Putu Diana Mahayani, Jean-Remy Makana, Yadvinder Malhi, Lorena Maniguaje Rincón, Asyraf Mansor, Angelo Gilberto Manzatto, Beatriz S Marimon, Ben Hur Marimon-Junior, Andrew R Marshall, Maria Pires Martins, Faustin M Mbayu, Marcelo Brilhante de Medeiros, Italo Mesones, Faizah Metali, Vianet Mihindou, Jerome Millet, William Milliken, Hugo F Mogollón, Jean-François Molino, Mohd Nizam Mohd Said, Abel Monteagudo Mendoza, Juan Carlos Montero, Sam Moore, Bonifacio Mostacedo, Linder Felipe Mozombite Pinto, Sharif Ahmed Mukul, Pantaleo K T Munishi, Hidetoshi Nagamasu, Henrique Eduardo Mendonça Nascimento, Marcelo Trindade Nascimento, David Neill, Reuben Nilus, Janaína Costa Noronha, Laurent Nsenga, Percy Núñez Vargas, Lucas Ojo, Alexandre A Oliveira, Edmar Almeida de Oliveira, Fidèle Evouna Ondo, Walter Palacios Cuenca, Susamar Pansini, Marcelo Petratti Pansonato, Marcos Ríos Paredes, Ekananda Paudel, Daniela Pauletto, Richard G Pearson, José Luis Marcelo Pena, R Toby Pennington, Carlos A Peres, Andrea Permana, Pascal Petronelli, Maria Cristina Peñuela Mora, Juan Fernando Phillips, Oliver L Phillips, Georgia Pickavance, Maria Teresa Fernandez Piedade, Nigel C A Pitman, Pierre Ploton, Andreas Popelier, John R Poulsen, Adriana Prieto, Richard B Primack, Hari Priyadi, Lan Qie, Adriano Costa Quaresma, Helder Lima de Queiroz, Hirma Ramirez-Angulo, José Ferreira Ramos, Neidiane Farias Costa Reis, Jan Reitsma, Juan David Cardenas Revilla, Terhi Riutta, Gonzalo Rivas-Torres, Iyan Robiansyah, Maira Rocha, Domingos de Jesus Rodrigues, M Elizabeth Rodriguez-Ronderos, Francesco Rovero, Andes H Rozak, Agustín Rudas, Ervan Rutishauser, Daniel Sabatier, Le Bienfaiteur Sagang, Adeilza Felipe Sampaio, Ismayadi Samsoedin, Manichanh Satdichanh, Juliana Schietti, Jochen Schöngart, Veridiana Vizoni Scudeller, Naret Seuaturien, Douglas Sheil, Rodrigo Sierra, Miles R Silman, Thiago Sanna Freire Silva, José Renan da Silva Guimarães, Murielle Simo-Droissart, Marcelo Fragomeni Simon, Plinio Sist, Thaiane R Sousa, Emanuelle de Sousa Farias, Luiz de Souza Coelho, Dominick V Spracklen, Suzanne M Stas, Robert Steinmetz, Pablo R Stevenson, Juliana Stropp, Rahayu S Sukri, Terry C H Sunderland, Eizi Suzuki, Michael D Swaine, Jianwei Tang, James Taplin, David M Taylor, J Sebastián Tello, John Terborgh, Nicolas Texier, Ida Theilade, Duncan W Thomas, Raquel Thomas, Sean C Thomas, Milton Tirado, Benjamin Toirambe, José Julio de Toledo, Kyle W Tomlinson, Armando Torres-Lezama, Hieu Dang Tran, John Tshibamba Mukendi, Roven D Tumaneng, Maria Natalia Umaña, Peter M Umunay, Ligia Estela Urrego Giraldo, Elvis H Valderrama Sandoval, Luis Valenzuela Gamarra, Tinde R Van Andel, Martin van de Bult, Jaqueline van de Pol, Geertje van der Heijden, Rodolfo Vasquez, César I A Vela, Eduardo Martins Venticinque, Hans Verbeeck, Rizza Karen A Veridiano, Alberto Vicentini, Ima Célia Guimarães Vieira, Emilio Vilanova Torre, Daniel Villarroel, Boris Eduardo Villa Zegarra, Jason Vleminckx, Patricio von Hildebrand, Vincent Antoine Vos, Corine Vriesendorp, Edward L Webb, Lee J T White, Serge Wich, Florian Wittmann, Roderick Zagt, Runguo Zang, Charles Eugene Zartman, Lise Zemagho, Egleé L Zent, Stanford Zent
Trees structure the Earth's most biodiverse ecosystem, tropical forests. The vast number of tree species presents a formidable challenge to understanding these forests, including their response to environmental change, as very little is known about most tropical tree species. A focus on the common species may circumvent this challenge. Here we investigate abundance patterns of common tree species using inventory data on 1,003,805 trees with trunk diameters of at least 10 cm across 1,568 locations1-6 in closed-canopy, structurally intact old-growth tropical forests in Africa, Amazonia and Southeast Asia...
January 10, 2024: Nature
https://read.qxmd.com/read/38199824/the-burden-of-recurrence-acute-pancreatitis-and-annual-event-rates-are-underestimated-because-of-high-rates-of-home-self-management
#40
JOURNAL ARTICLE
Phil J Greer, Jessica M Gibson, Jason Swoger, Tory Moore, David C Whitcomb
BACKGROUND/OBJECTIVES: The event-rate of recurrent acute pancreatitis (RAP) in patient populations is critical for powering research studies. We hypothesize that some patients manage RAP attacks at home, reducing event rate estimations based on counting emergency department (ED) visits and hospitalizations only. The aim of this study was to determine the rates of home self-management of recurrent acute pancreatitis compared to ED visits and hospitalizations. METHODS: An anonymous 8-question survey was sent to 1825 individuals on an email list of individuals with a history of acute pancreatitis (AP) or chronic pancreatitis or interest in pancreatic diseases...
December 27, 2023: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
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