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https://www.readbyqxmd.com/read/29053439/factors-influencing-indonesian-women-s-use-of-maternal-health-care-services
#1
Anna Kurniati, Ching-Min Chen, Ferry Efendi, Sarni Maniar Berliana
Employing the 2012 Indonesia Demographic and Health Survey data, we aimed to examine factors influencing married women to use maternity services. Data of married women who had given birth in the last five years before the survey were included in the analysis (n = 14,672). Factors of education, employment, women's age at first marriage, age at first birth, spousal education difference, contraceptive use, place of residence, and woman's attitude toward wife beating were associated with the use of antenatal care, institutional delivery, and postnatal care services...
October 20, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/29039548/-corrigendum-farnesoid-x-receptor-deletion-improves-cardiac-function-structure-and-remodeling-following-myocardial-infarction-in-mice
#2
Jianshu Gao, Xiaoqiang Liu, Bingjian Wang, Haiyan Xu, Qiang Xia, Tianfei Lu, Fang Wang
Following the publication of this article, an interested reader drew to our attention that we had incorrectly reported (in the Materials and methods section, 'Western blot analysis', on p. 674) that the anti-farnesoid X receptor (FXR) antibody of Cell Signalling Technology, Inc., cat. no. #12295, had been used in this study to probe for FXR. In fact, the antibodies used in the above-mentioned study were a gift from the group of Dr Xin-Liang Ma at Thomas Jefferson University (Philadelphia, PA, USA), as referenced in the following article: [Pul J, Yuan A, Shan P, Gao E, Wang X, Wang Y, Lau WB, Koch W, Xin-Ma XL and He B: Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury...
October 3, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29039522/-retracted-atorvastatin-protects-cardiomyocytes-against-ogd-r%C3%A2-induced-apoptosis-by-inhibiting-mir%C3%A2-199a%C3%A2-5p
#3
Yong Li, Ting Jiang, Xingli Fu, Hao Xu, Jianguo Ji
Following the publication of this article, the authors find that they are not able to reproduce certain of the results presented in this paper. Consequently, the authors have decided to retract this paper from the publication. All of the authors agree to this retraction. The authors sincerely regret this decision, and apologize to the Editor and to the readership of the Journal for any inconvenience caused. [The original article was published in Molecular Medicine Reports 16: 3807-3816, 2017; DOI: 10.3892/mmr...
September 28, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29037574/county-level-assessment-of-united-states-kindergarten-vaccination-rates-for-measles-mumps-rubella-mmr-for-the-2014-2015-school-year
#4
Sheryl A Kluberg, Denise P McGinnis, Yulin Hswen, Maimuna S Majumder, Mauricio Santillana, John S Brownstein
United States kindergarten measles-mumps-rubella (MMR) vaccination rates are typically reported at the state level by the Centers for Disease Control and Prevention (CDC). The lack of local MMR data prevents identification of areas with low vaccination rates that would be vulnerable to the spread of disease. We collected county-level vaccination rates for the 2014-2015 school year with the objective of identifying these regions. We requested county-level kindergarten vaccination data from state health departments, and mapped these data to visualize geographic patterns in achievement of the 95% MMR vaccination target...
October 13, 2017: Vaccine
https://www.readbyqxmd.com/read/29036392/update-from-the-advisory-committee-on-immunization-practices
#5
Sean T O'Leary, David W Kimberlin
The Advisory Committee on Immunization Practices (ACIP), a group of medical and public health experts, meets 3 times per year to develop recommendations for vaccine use in the United States. The group has 15 voting members, and each member's term is 4 years. ACIP members and Centers for Disease Control and Prevention (CDC) staff discuss the epidemiology of vaccine-preventable diseases and vaccine research, effectiveness, safety data, and clinical trial results. Representatives from the American Academy of Pediatrics (Carrie L...
September 25, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29033428/the-efficacy-of-reduced-dose-dasatinib-as-a-subsequent-therapy-in-patients-with-chronic-myeloid-leukemia-in-the-chronic-phase-the-ld-cml-study-of-the-kanto-cml-study-group
#6
Noriyoshi Iriyama, Ohashi Kazuteru, Satoshi Hashino, Shinya Kimura, Chiaki Nakaseko, Hina Takano, Masayuki Hino, Michihiro Uchiyama, Satoshi Morita, Junichi Sakamoto, Hisashi Sakamaki, Koiti Inokuchi
Objective The aim of this study was to prospectively investigate the efficacy and safety profiles of low-dose dasatinib therapy (50 mg once daily). Methods Patients with chronic myeloid leukemia in the chronic phase (CML-CP) who were being treated with low-dose imatinib (≤200 mg/day), but were resistant to this agent were enrolled in the current study (referred to as the LD-CML study). Results There subjects included 9 patients (4 men and 5 women); all were treated with dasatinib at a dose of 50 mg once daily...
October 16, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29032513/sudden-blast-phase-in-chronic-myeloid-leukemia-developed-during-nilotinib-therapy-after-major-molecular-response-was-achieved
#7
Yosuke Okada, Ken Sato, Shinichi Kobayashi, Shigeki Nagao, Kosuke Takano, Masahiro Teramoto, Noriaki Tachi, Toshikuni Kawamura, Toshikatsu Horiuchi, Shoichiro Kato, Reina Saga, Takaaki Maekawa, Takeshi Yamamura, Junichi Watanabe, Ayako Kobayashi, Fumihiko Kimura
Sudden blast phase (SBP) is a rare event in which patients with chronic myeloid leukemia (CML) in complete cytogenetic response (CCyR) rapidly progress to the blast phase. Few patients on second-generation tyrosine kinase inhibitors (2nd TKIs) have been reported to develop SBP. Here, we report a 45-year-old man diagnosed with CML in the chronic phase in April 2008 and immediately started on imatinib therapy. He achieved CCyR 12 months after starting imatinib therapy. Imatinib was followed by treatment with the 2nd TKIs nilotinib and dasatinib from January 2011 to yield a better response...
October 14, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/29031695/-hesitant-compliers-qualitative-analysis-of-concerned-fully-vaccinating-parents
#8
Stephanie L Enkel, Katie Attwell, Thomas L Snelling, Hayley E Christian
OBJECTIVE: Some parents are hesitant about vaccines and yet still vaccinate their children. Vaccine behaviours are not fixed and parents who are concerned but nonetheless adherent to standard schedules could switch to an unconventional schedule, delaying or cherry-picking vaccines. There is a need to better understand vaccine hesitancy in specific contexts, acknowledging cultural and geographical variation, to ensure interventions targeting hesitancy are well directed and received. METHODS: To identify the behaviours, knowledge and attitudes of 'hesitant compliers' in Perth, Western Australia, nine one-on-one in-depth interviews were conducted with vaccinating parents of children (<5 years) who were identified as being hesitant...
October 11, 2017: Vaccine
https://www.readbyqxmd.com/read/29029941/timeliness-of-childhood-vaccination-in-the-federated-states-of-micronesia
#9
Ashley Tippins, Andrew J Leidner, Mehreen Meghani, Aja Griffin, Louisa Helgenberger, Mawuli Nyaku, J Michael Underwood
BACKGROUND: Vaccination coverage is typically measured as the proportion of individuals who have received recommended vaccine doses by the date of assessment. This approach does not provide information about receipt of vaccines by the recommended age, which is critical for ensuring optimal protection from vaccine-preventable diseases (VPDs). OBJECTIVE: To assess vaccination timeliness in the Federated States of Micronesia (FSM), and the projected impact of suboptimal vaccination in the event of an outbreak...
October 10, 2017: Vaccine
https://www.readbyqxmd.com/read/29028959/effectiveness-of-measles-vaccination-and-immune-globulin-post-exposure-prophylaxis-in-an-outbreak-setting-new-york-city-2013
#10
Robert J Arciuolo, Rachel R Jablonski, Jane R Zucker, Jennifer B Rosen
Background: Measles, mumps, and rubella vaccine (MMR) or immune globulin (IG) are routinely used for measles post-exposure prophylaxis (PEP). However, current literature on the effectiveness of measles PEP is limited and variable. Here, we examined the effectiveness of MMR and IG PEP among children exposed to measles during an outbreak in New York City (NYC) in 2013. Methods: Contacts were identified by the NYC Department of Health and Mental Hygiene between 13 March 2013 and 30 June 2013...
September 23, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29027647/dasatinib-associated-reversible-demyelinating-peripheral-polyneuropathy-in-a-case-of-chronic-myeloid-leukemia
#11
Takashi Ishida, Naoyuki Akagawa, Tomomi Miyata, Naomi Tominaga, Takahiro Iizuka, Masaaki Higashihara, Takahiro Suzuki, Koji Miyazaki
Tyrosine kinase inhibitors (TKIs) are essential for the treatment of chronic myeloid leukemia (CML). Adverse effects of dasatinib have been reported; however, few reports have highlighted the association between dasatinib and demyelinating peripheral neuropathy (DPN). We report a patient with CML who developed acute onset of DPN associated with dasatinib therapy. A 46-year-old Japanese woman was treated with dasatinib for 7 months after the diagnosis of CML and she achieved a major molecular response (MMR)...
October 13, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/29027261/prognostic-significance-of-additional-chromosomal-abnormalities-at-the-time-of-diagnosis-in-patients-with-chronic-myeloid-leukemia-treated-with-frontline-tyrosine-kinase-inhibitors
#12
Ahmad Alhuraiji, Hagop Kantarjian, Prajwal Boddu, Farhad Ravandi, Gautam Borthakur, Courtney DiNardo, Naval Daver, Tapan Kadia, Naveen Pemmaraju, Sherry Pierce, Guillermo Garcia-Manero, William Wierda, Srdan Verstovsek, Elias Jabbour, Jorge Cortes
Additional cytogenetic abnormalities (ACA) are considered a high risk feature in chronic myeloid leukemia (CML). However, its prognostic significance at the time of diagnosis in the setting of new tyrosine kinase inhibitors (TKIs) is less well understood. Patients with CML in CP with or without ACA at diagnosis treated with frontline TKIs in prospective clinical trials were analyzed for outcomes. Among 603 patients treated, 29 (5%) had ACA. Patients with ACA included 2 of 72 (2.8%) treated with imatinib 400 mg, 9 of 207 (4...
October 13, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/29025581/clonal-chromosomal-aberrations-in-philadelphia-negative-cells-such-as-monosomy-7-and-trisomy-8-may-persist-for-years-with-no-impact-on-the-long-term-outcome-in-patients-with-chronic-myeloid-leukemia
#13
Ewa M Wasilewska, Barbara Panasiuk, Michał Gniot, Anna Sawicka, Katarzyna Kozłowska, Krzysztof Lewandowski, Janusz Kłoczko, Alina T Midro
The appearance of clonal chromosomal aberrations in Philadelphia negative cells (CCA/Ph-) during the treatment of chronic myeloid leukemia (CML) was recently confirmed. Importance of these findings has not been clearly defined. We present data on the time of appearance, persistence, size of the CCA/Ph- clone in terms of drugs used and hematological, cytogenetic and molecular response rates. The focus was on the peripheral blood cytopenias and myelodysplastic changes in the bone marrow microscopic evaluation...
October 2017: Cancer Genetics
https://www.readbyqxmd.com/read/29023430/vaccination-coverage-for-selected-vaccines-exemption-rates-and-provisional-enrollment-among-children-in-kindergarten-united-states-2016-17-school-year
#14
Ranee Seither, Kayla Calhoun, Erica J Street, Jenelle Mellerson, Cynthia L Knighton, Ashley Tippins, J Michael Underwood
State and local school vaccination requirements help protect students and communities against vaccine-preventable diseases (1). CDC reports vaccination coverage and exemption data for children attending kindergarten (kindergartners) collected by federally funded immunization programs in the United States.* The typical age range for kindergartners is 4-6 years. Although vaccination requirements vary by state (the District of Columbia [DC] is counted as a state in this report.), the Advisory Committee on Immunization Practices recommends that children in this age range have received, among other vaccinations, 5 doses of diphtheria, tetanus, and acellular pertussis vaccine (DTaP), 2 doses of measles, mumps, and rubella vaccine (MMR), and 2 doses of varicella vaccine (2)...
October 13, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29020502/persistence-of-dna-adducts-hypermutation-and-acquisition-of-cellular-resistance-to-alkylating-agents-in-glioblastoma
#15
R J Head, M F Fay, L Cosgrove, K Y C Fung, D Rundle-Thiele, J H Martin
Glioblastoma is a lethal form of brain tumour usually treated by surgical resection followed by radiotherapy and an alkylating chemotherapeutic agent. Key to the success of this multimodal approach is maintaining apoptotic sensitivity of tumour cells to the alkylating agent. This initial treatment likely establishes conditions contributing to development of drug resistance as alkylating agents form the O(6)-methylguanine adduct. This activates the mismatch repair (MMR) process inducing apoptosis and mutagenesis...
October 11, 2017: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/29020324/mumps-outbreak-in-a-highly-vaccinated-university-affiliated-setting-before-and-after-a-measles-mumps-rubella-mmr-vaccination-campaign-iowa-july-2015-may-2016
#16
Minesh Shah, Patricia Quinlisk, Andrew Weigel, Jacob Riley, Lisa James, James Patterson, Carole Hickman, Paul A Rota, Rebekah Schicker, Nakia Clemmons, Nicholas Kalas, Cristina Cardemil
Background: In response to a mumps outbreak at the University of Iowa and surrounding community, university, state, and local health officials implemented a vaccination campaign targeting students <25 years of age with an additional dose of measles-mumps-rubella (MMR) vaccine. Over 4,700 vaccine campaign doses were administered; 97% were documented third doses. We describe the epidemiology of the outbreak before and after the campaign, focusing on cases in university students. Methods: Mumps cases were identified from reportable disease databases and university health system records...
August 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28989591/familial-colorectal-cancer-type-x-in-central-iran-a-new-clinicopathologic-description
#17
Mehrdad Zeinalian, Mahdi Hadian, Morteza Hashemzadeh-Chaleshtori, Rasoul Salehi, Mohammad Hassan Emami
Background: Familial colorectal cancer type X (FCCX) is a subtype of mismatch repair (MMR)-proficient colorectal cancerin which the patients are clinically at risk for Lynch syndrome (LS), a common hereditary cancer predisposing syndrome. In this study, we described a new clinicopathological feature of the condition in central Iran. Materials and Methods: We designed a descriptive, retrospective study to screenat-risk colorectal cancer (CRC) patients, using Amsterdam II criteria and Molecular analysis in Isfahan (central Iran) throughout 2000-2013 period...
July 1, 2017: International Journal of Hematology-oncology and Stem Cell Research
https://www.readbyqxmd.com/read/28988047/the-identification-of-lynch-syndrome-in-congolese-colorectal-cancer-patients
#18
Henriette Poaty, Chandra Aba Gandzion, Isabelle Soubeyran, Déby Gassaye, Jean Félix Peko, Jean Bernard Nkoua Bon, Charles Gombé Mbalawa
BACKGROUND: We aimed to investigate the prevalence of Lynch syndrome as one of hereditary causes of colorectal cancer (CRC) among young Congolese individuals affected by the CRC, and to define methods for diagnosis in Congo Brazzaville. METHODS: We conducted a transversal cohort study of 34 patients having a CRC with a family history for a period of eight years. They were selected among 89 CRCs of any type from the Bethesda guidelines criteria combined with pedigrees...
October 5, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28987974/post-boosting-of-classification-boundary-for-imbalanced-data-using-geometric-mean
#19
Jie Du, Chi-Man Vong, Chi-Man Pun, Pak-Kin Wong, Weng-Fai Ip
In this paper, a novel imbalance learning method for binary classes is proposed, named as Post-Boosting of classification boundary for Imbalanced data (PBI), which can significantly improve the performance of any trained neural networks (NN) classification boundary. The procedure of PBI simply consists of two steps: an (imbalanced) NN learning method is first applied to produce a classification boundary, which is then adjusted by PBI under the geometric mean (G-mean). For data imbalance, the geometric mean of the accuracies of both minority and majority classes is considered, that is statistically more suitable than the common metric accuracy...
September 14, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/28987677/quantification-accuracy-of-neuro-oncology-pet-data-as-a-function-of-emission-scan-duration-in-pet-mr-compared-to-pet-ct
#20
Stefan Wampl, Ivo Rausch, Tatjana Traub-Weidinger, Thomas Beyer, Martin Gröschl, Jacobo Cal-González
OBJECTIVES: To evaluate and compare the effect of reduced acquisition time, as a surrogate of injected activity, on the PET quantification accuracy in PET/CT and PET/MR imaging. METHODS: Twenty min (18)F-FDG phantom measurements and 10min (18)F-FET brain scans were acquired in a Biograph-True-Point-True-View PET/CT (n=8) and a Biograph mMR PET/MR (n=16). Listmode data were repeatedly split into frames of 1min to 10min length and reconstructed using two different reconstruction settings of a 3D-OSEM algorithm: with post-filtering ("OSEM"), and without post-filtering but with resolution recovery ("PSF")...
October 2017: European Journal of Radiology
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