keyword
https://read.qxmd.com/read/38344580/critical-case-of-a-preterm-infant-infected-with-respiratory-syncytial-virus-managed-in-the-pediatric-intensive-care-unit-a-case-report
#1
Amaal F Alshihabi, Saleh A Alnass, Fatimah S Alsammak, Muhammad S Al Abdrabalnabi
We describe a critical case of a respiratory syncytial virus (RSV) infection in a preterm infant resulting in respiratory failure with advanced respiratory interventions and discharge from our hospital without the requirement for home oxygen therapy or tube feeding. The infant, delivered at 35 weeks gestation due to a premature rupture of the membranes with a birth weight of 2 kg, initially demonstrated a stable postnatal course. The baby required no resuscitation, with Apgar scores of 8 and 9 at one and five minutes, respectively...
January 2024: Curēus
https://read.qxmd.com/read/37773858/the-value-of-hematocrit-for-predicting-bronchopulmonary-dysplasia-in-very-low-birth-weight-preterm-infants
#2
JOURNAL ARTICLE
Xuesong Wang, Shushu Wang, Mingwu Chen, Yong Lv, Xueyu Chen, Chuanzhong Yang
To determine hematocrit (HCT) and to identify independent risk factors for predicting bronchopulmonary dysplasia (BPD) in preterm infants with very low birth weight (VLBW) infants. This retrospective study included 296 premature infants with VLBW in the neonatal intensive care unit of the First Affiliated Hospital of the University of Science and Technology of China between January 2015 and December 2019. Maternal pregnant information and clinical information as well as hematological parameters of preterm babies were collected and compared...
September 29, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37661670/outcomes-of-newborns-with-tracheostomy-single-center-experience
#3
JOURNAL ARTICLE
Ümit Ayşe Tandırcıoğlu, Özge Doğan, R Önder Günaydın, Şule Yiğit, H Tolga Çelik
BACKGROUND: Babies with severe bronchopulmonary dysplasia (BPD) are discharged with the support of a home-type mechanical ventilator, after opening a tracheostomy. In addition, although rare, tracheostomy is required in the neonatal period in congenital airway malformations. Early tracheostomy is appropriate to prevent complications due to prolonged intubation. We aimed to find the appropriate time for tracheostomy by examining the tracheostomy opening and closing times, complications and demographic characteristics of the patients, who were hospitalized and underwent tracheostomy in our neonatal intensive care unit...
2023: Turkish Journal of Pediatrics
https://read.qxmd.com/read/37593258/colostrum-and-preterm-babies-a-systematic-review
#4
REVIEW
Ethan Slouha, Zoe S Anderson, Nana Mansa N Ankrah, Amy E Kalloo, Vasavi Rakesh Gorantla
Colostrum from mothers is rich in immunomodulating bio-factors such as immunoglobulins (IgA), lactoferrin, and oligosaccharides and supports gut microbial and inflammatory processes. The support in these processes may provide some relief for infants who are born pre-term. Pre-term infants are more likely to develop necrotizing enterocolitis (NEC), late-onset sepsis (LOS), and ventilator-acquired/associated pneumonia (VAP). Due to the components of colostrum, there may be incentives towards early administration for preterm infants...
July 2023: Curēus
https://read.qxmd.com/read/37362106/an-innovative-single-staged-surgical-repair-of-benign-tracheoesophageal-fistula-a-case-report
#5
JOURNAL ARTICLE
Anand Velusamy, Aishwarya Anand, Sridurga Janarthanan, Baby Sasna
UNLABELLED: Tracheo-oesophageal fistula (TOF) is defined as a pathological connection between the trachea and the oesophagus, leading to a spillover of oral and gastric secretions into the respiratory tract causing aspiration. The cause of TOF may be congenital or acquired. In this case report, a 48 years old female with acquired TOF, has been reported. The patient was on ventilator support for COVID-associated pneumonia and its complication with endotracheal tube for 3 weeks and then tracheostomy was done...
May 3, 2023: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/36477637/closed-versus-open-endotracheal-tube-suction-in-mechanically-ventilated-neonates-a-randomized-controlled-trial
#6
RANDOMIZED CONTROLLED TRIAL
Ajaya Kumar Gahan, Suksham Jain, Supreet Khurana, Deepak Chawla
UNLABELLED: This study aimed to evaluate the effect of closed versus open endotracheal tube suction in reducing ventilator-associated pneumonia in mechanically ventilated neonates. In this open-label, parallel-group, randomized controlled trial with allocation concealment, ventilated neonates (≥ 28 weeks and ≥ 800 g) were either allocated to the closed-suction group (n = 41) or open-suction group (n = 39). The ventilator circuit of the babies enrolled in the closed-suction group was attached to the closed-suction catheter on the requirement of their first suction, and it was changed after every 48 h or earlier if visibly soiled whereas babies enrolled in the open-suction group were suctioned with a new suction catheter each time they require suction...
February 2023: European Journal of Pediatrics
https://read.qxmd.com/read/36281089/how-to-survive-a-periviable-birth-baby-with-birth-weight-of-450g-a-case-report
#7
JOURNAL ARTICLE
Binzhi Tang, Qiying Ling, Qian Yang, Maojun Li, Wei Shi, Qing Wu
RATIONALE: An increasing number of periviable birth newborns (PVBs) have emerged with concurrent growing high-risk pregnancy. To date, postnatal management of PVBs remains one of the most challenging issues and limited studies have been reported. PATIENT CONCERNS: A female baby born at 230/7 weeks of gestation with birth weight of 450g. DIAGNOSIS: PVB baby, respiratory distress syndrome (RDS), ventilator associated pneumonia (VAP), intraventricular hemorrhage (IVH), metabolic bone disease of prematurity (MBDP), transient hypothyroxinemia of prematurity (THOP), bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP)...
October 21, 2022: Medicine (Baltimore)
https://read.qxmd.com/read/35935164/management-of-neonatal-sepsis-with-covid-19-infection-in-a-premature-newborn-a-case-report
#8
Mahbod Kaveh, Seyyed Mohsen Sadatinejad
INTRODUCTION: Neonates appear to be less affected by COVID-19 than adults, yet COVID-19 has been a challenge for all medical specialties, including neonatal intensive care unit (NICU) specialists. Unfortunately, current knowledge about the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is limited. This case report explains how COVID-19 neonatal sepsis was treated with immunomodulatory agents. CASE PRESENTATION: In this case, we present a premature male newborn who was ill...
August 2, 2022: Journal of Neonatal Nursing: JNN
https://read.qxmd.com/read/35685096/complicated-covid-19-in-pregnancy-maternal-and-neonatal-outcomes-a-case-report
#9
Mouna Gara, Eya Sahraoui, Wafa Dhouib, Dhekra Toumi, Olfa Zoukar, Meriem Mehdi, Ali Jlali, Raja Faleh, Lotfi Grati
The novel coronavirus disease 2019 (COVID-19) has exposed vulnerable populations, including pregnant women, to an unprecedented public health crisis. According to recent data, pregnancy in COVID-19 patients is associated with increased hospitalization, admission to the intensive care unit (ICU) and intubation. It has been suggested that pregnancy induced immune responses and cardiorespiratory changes can exaggerate the course of the COVID-19. The present is a case of a pregnant woman who presented with critical respiratory failure secondary to COVID-19 resulted in her admission to the ICU and mechanical ventilator support...
2022: Pan African Medical Journal
https://read.qxmd.com/read/35626436/pneumonia-classification-from-x-ray-images-with-inception-v3-and-convolutional-neural-network
#10
JOURNAL ARTICLE
Muhammad Mujahid, Furqan Rustam, Roberto Álvarez, Juan Luis Vidal Mazón, Isabel de la Torre Díez, Imran Ashraf
Pneumonia is one of the leading causes of death in both infants and elderly people, with approximately 4 million deaths each year. It may be a virus, bacterial, or fungal, depending on the contagious pathogen that damages the lung's tiny air sacs (alveoli). Patients with underlying disorders such as asthma, a weakened immune system, hospitalized babies, and older persons on ventilators are all at risk, particularly if pneumonia is not detected early. Despite the existing approaches for its diagnosis, low accuracy and efficiency require further research for more accurate systems...
May 21, 2022: Diagnostics
https://read.qxmd.com/read/35096527/post-covid-pneumonia-pulmonary-fibrosis-and-encephalitis-in-a-term-neonate-with-prenatal-exposure-to-sars-cov-2-a-case-report
#11
Vaanathi Hementha Kumar, Chandrakumar Natarajan, S Shivabalan, C Gopinath, D Dhanalakshmi, Siddharth, Shyam, Ahalya, Maria, Jean, Rajashree
9 day old term baby girl was referred at day 9 of illness to our tertiary Covid neonatal intensive care unit with prenatal exposure to SARS Cov2 infection. She had progressive respiratory distress and hypoxia needing invasive ventilation and developed features of severe pneumonia needing steroids and intravenous immunoglobulin. Baby also developed pulmonary fibrosis at 5 weeks following the pneumonia and features of encephalitis. Both were self resolving and responded to inhaled steroids and immunomodulators...
January 22, 2022: IDCases
https://read.qxmd.com/read/35006378/same-baby-different-care-variations-in-practice-between-neonatologists-and-pediatric-intensivists
#12
JOURNAL ARTICLE
Liron Borenstein-Levin, Ori Hochwald, Josef Ben-Ari, Gil Dinur, Yoav Littner, Danny Eytan, Amir Kugelman, Michael Halberthal
UNLABELLED: The aim of the study was to identify and explore areas in neonatal care in which significant differences in clinical care exist, among neonatal intensive care (NICU) and pediatric intensive care (PICU) physicians. A questionnaire presenting three common scenarios in neonatal critical care-severe pneumonia, post-cardiac-surgery care, and congenital diaphragmatic hernia (CDH) was electronically sent to all PICU and NICU physicians in Israel. The survey was completed by 110 physicians...
April 2022: European Journal of Pediatrics
https://read.qxmd.com/read/34768118/treatment-of-covid-19-in-pregnant-women-a-systematic-review-and-meta-analysis
#13
REVIEW
Steven Giesbers, Edwina Goh, Tania Kew, John Allotey, Vanessa Brizuela, Edna Kara, Heinke Kunst, Mercedes Bonet, Shakila Thangaratinam
OBJECTIVE: Clinical trials evaluating pharmacological and non-pharmacological treatment of COVID-19, either excluded pregnant women or included very few women. Unlike the numerous systematic reviews on prevalence, symptoms and adverse outcomes of COVID-19 in pregnancy, there are very few on the effects of treatment on maternal and neonatal outcomes in pregnancy. We undertook a systematic review of all published and unpublished studies on the effects of pharmacological and non-pharmacological interventions for COVID-19 on maternal and neonatal pregnancy outcomes...
December 2021: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://read.qxmd.com/read/34726511/improving-early-colostrum-feeding-in-a-tertiary-neonatal-intensive-care-unit-a-quality-improvement-initiative
#14
JOURNAL ARTICLE
Swati Manerkar, Pavan Kalamdani, Saikat Patra, Thaslima Kalathingal, Jayashree Mondkar
Background and Objective: Colostrum feeding is known for its immune benefits for reduction in nosocomial sepsis, necrotizing enterocolitis, and ventilator-associated pneumonias. Colostrum feeding also helps in improving breastfeeding rates and early discharge of vulnerable neonatal intensive care unit (NICU) babies. The objective of this study was to improve early colostrum feeding/oropharyngeal colostrum administration in a busy tertiary NICU in India. Methods: Multiple plan-do-study-act (PDSA) cycles were conducted from January 2020 to September 2020 to improve early colostrum feeding rates in NICU babies to >60%...
February 2022: Breastfeeding Medicine
https://read.qxmd.com/read/34358491/hypothermia-for-moderate-or-severe-neonatal-encephalopathy-in-low-income-and-middle-income-countries-helix-a-randomised-controlled-trial-in-india-sri-lanka-and-bangladesh
#15
RANDOMIZED CONTROLLED TRIAL
Sudhin Thayyil, Stuti Pant, Paolo Montaldo, Deepika Shukla, Vania Oliveira, Phoebe Ivain, Paul Bassett, Ravi Swamy, Josephine Mendoza, Maria Moreno-Morales, Peter J Lally, Naveen Benakappa, Prathik Bandiya, Indramma Shivarudhrappa, Jagadish Somanna, Usha B Kantharajanna, Ankur Rajvanshi, Sowmya Krishnappa, Poovathumkal K Joby, Kumutha Jayaraman, Rema Chandramohan, Chinnathambi N Kamalarathnam, Monica Sebastian, Indumathi A Tamilselvam, Usha D Rajendran, Radhakrishnan Soundrarajan, Vignesh Kumar, Harish Sudarsanan, Padmesh Vadakepat, Kavitha Gopalan, Mangalabharathi Sundaram, Arasar Seeralar, Prakash Vinayagam, Mohamed Sajjid, Mythili Baburaj, Kanchana D Murugan, Babu P Sathyanathan, Elumalai S Kumaran, Jayashree Mondkar, Swati Manerkar, Anagha R Joshi, Kapil Dewang, Swapnil M Bhisikar, Pavan Kalamdani, Vrushali Bichkar, Saikat Patra, Kapil Jiwnani, Mohammod Shahidullah, Sadeka C Moni, Ismat Jahan, Mohammad A Mannan, Sanjoy K Dey, Mst N Nahar, Mohammad N Islam, Kamrul H Shabuj, Ranmali Rodrigo, Samanmali Sumanasena, Thilini Abayabandara-Herath, Gayani K Chathurangika, Jithangi Wanigasinghe, Radhika Sujatha, Sobhakumar Saraswathy, Aswathy Rahul, Saritha J Radha, Manoj K Sarojam, Vaisakh Krishnan, Mohandas K Nair, Sahana Devadas, Savitha Chandriah, Harini Venkateswaran, Constance Burgod, Manigandan Chandrasekaran, Gaurav Atreja, Pallavi Muraleedharan, Jethro A Herberg, W K Kling Chong, Neil J Sebire, Ronit Pressler, Siddarth Ramji, Seetha Shankaran
BACKGROUND: Although therapeutic hypothermia reduces death or disability after neonatal encephalopathy in high-income countries, its safety and efficacy in low-income and middle-income countries is unclear. We aimed to examine whether therapeutic hypothermia alongside optimal supportive intensive care reduces death or moderate or severe disability after neonatal encephalopathy in south Asia. METHODS: We did a multicountry open-label, randomised controlled trial in seven tertiary neonatal intensive care units in India, Sri Lanka, and Bangladesh...
September 2021: Lancet Global Health
https://read.qxmd.com/read/34185807/covid-19-and-pregnancy-an-umbrella-review-of-clinical-presentation-vertical-transmission-and-maternal-and-perinatal-outcomes
#16
JOURNAL ARTICLE
Agustín Ciapponi, Ariel Bardach, Daniel Comandé, Mabel Berrueta, Fernando J Argento, Federico Rodriguez Cairoli, Natalia Zamora, Victoria Santa María, Xu Xiong, Sabra Zaraa, Agustina Mazzoni, Pierre Buekens
BACKGROUND: We conducted an overview of systematic reviews (SRs) summarizing the best evidence regarding the effect of COVID-19 on maternal and child health following Cochrane methods and PRISMA statement for reporting (PROSPERO-CRD42020208783). METHODS: We searched literature databases and COVID-19 research websites from January to October 2020. We selected relevant SRs reporting adequate search strategy, data synthesis, risk of bias assessment, and/or individual description of included studies describing COVID-19 and pregnancy outcomes...
2021: PloS One
https://read.qxmd.com/read/34092858/incidence-of-device-associated-healthcare-associated-infections-from-a-neurosurgical-intensive-care-unit-of-a-tertiary-care-center-a-retrospective-analysis
#17
JOURNAL ARTICLE
Gokuldas Menon, Avanthi Subramanian, Poornima Baby, Nimesh Daniel, R Radhika, Mathew George, Sajesh Menon
Background: Deviceassociated infections (DAIs) increase the morbidity and mortality in the intensive care unit (ICU). Studies from the neurosurgical ICU in developing countries are sparse. Aims: The aim of this study was to assess the incidence of device-associated healthcare associated infections, pathogens isolated, antibiotic resistance, and mortality in neurosurgical ICU. Settings and Design: A retrospective study was conducted in the neurosurgical ICU of a tertiary care center...
July 2020: Anesthesia, Essays and Researches
https://read.qxmd.com/read/33944814/pneumococcal-septic-shock-after-neonatal-respiratory-syncytial-virus-bronchiolitis-a-case-report-and-literature-review
#18
JOURNAL ARTICLE
Antonella Di Caprio, Elena Coccolini, Paola Zagni, Eleonora Vaccina, Laura Lucaccioni, Licia Lugli, Lorenzo Iughetti, Alberto Berardi
BACKGROUND: Bronchiolitis is a common cause of hospitalisation of infants less than a year old, with most infants recovering without complications. Respiratory syncytial virus (RSV) is a leading cause of bronchiolitis. Antimicrobial stewardship programmes do not recommend antibiotics for viral infections in neonates unless documented evidence of secondary bacterial infection is present. CASE REPORT: We present the case of a 7-day-old infant admitted to hospital with chest retractions and fever...
April 30, 2021: Acta Bio-medica: Atenei Parmensis
https://read.qxmd.com/read/33851733/severe-herpes-virus-6-interstitial-pneumonia-in-an-infant-with-three-variants-in-genes-predisposing-to-lung-disease
#19
JOURNAL ARTICLE
Domenico Umberto De Rose, Cinzia Auriti, Simona Lozzi, Luana Coltella, Livia Piccioni, Sabrina Rossi, Antonio Novelli, Rossella Iannotta, Teresa Pianini, Simonetta Picone, Piermichele Paolillo, Ferdinando Savignoni, Irma Capolupo, Maria Cristina Digilio, Renato Cutrera, Andrea Dotta
Infections due to human herpesvirus 6 (HHV-6) are frequent during early childhood. Usually, they have a favorable clinical course. Conversely, HHV-6 congenital infections occur in about 1% of neonates and may present with more severe clinical pictures. HHV-6 can be found in lung tissues and bronchoalveolar lavage (BAL) samples from patients with pneumonia and in immunocompromised patients can cause mild to severe pneumonia. In neonates, the role of HHV-6 in the genesis of severe pneumonia is poorly defined still now...
August 2021: Journal of Medical Virology
https://read.qxmd.com/read/33661873/perinatal-covid-19-a-case-report-literature-review-and-proposal-of-a-national-system-for-case-record
#20
REVIEW
Victoria Lima-Rogel, Raúl Villegas-Silva, Alejandra Coronado-Zarco, Isaac Estrada-Ruelas, Alma R Sánchez-De la Vega, Raúl H Muro-Flores, Mónica Villa-Guillén
BACKGROUND: On March 11, 2020, the World Health Organization declared the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, and on February 28, Mexico reported its first case. Internationally, cases in newborns are few and the outcomes, in general, are good. There is no certainty of possible vertical transmission, and the presence of the virus in human milk is improbable. The gold standard for diagnosis is the reverse transcription-polymerase chain reaction (RT-PCR) test...
2021: Boletín Médico del Hospital Infantil de México
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