Yann Le Teurnier, Bertrand Rozec, Cecile Degryse, François Levy, Youcef Miliani, Gilles Godet, George Daccache, Cyrille Truc, Eric Steinmetz, Alexandre Ouattara, Bernard Cholley, Jean-Marc Malinovsky, Denis Portier, Gregory Dupont, Darius Liutkus, Pierre Viard, Morgane Pere, Benjamin Daumas-Duport, Pierre-Aubin Magras, Mickael Vourc'h
BACKGROUND: Whether the optimization of cerebral oxygenation based on regional cerebral oxygen saturation (rSO2 ) monitoring reduces the occurrence of cerebral ischemic lesions is unknown. METHODS: This multicenter, randomized, controlled trial recruited adults admitted for scheduled carotid endarterectomy. Patients were randomized between the standard of care or optimization of cerebral oxygenation based on rSO2 monitoring using near-infrared spectroscopy. In the intervention group, in case of a decrease in rSO2 in the intervention, the following treatments were sequentially recommended: (1) increasing oxygenotherapy, (2) reducing the tidal volume, (3) legs up-raising, (4) performing a fluid challenge and (5) initiating vasopressor support...
May 4, 2024: Anaesthesia, Critical Care & Pain Medicine