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https://www.readbyqxmd.com/read/29457477/enabling-choice-recovery-and-participation-evidence-based-early-intervention-support-for-psychosocial-disability-in-the-national-disability-insurance-scheme
#1
Laura Hayes, Lisa Brophy, Carol Harvey, Juan Jose Tellez, Helen Herrman, Eoin Killackey
OBJECTIVES: The aim of this study was to identify the most effective interventions for early intervention in psychosocial disability in the National Disability Insurance Scheme (NDIS) through an evidence review. METHODS: A series of rapid reviews were undertaken to establish possible interventions for psychosocial disability, to develop our understanding of early intervention criteria for the NDIS and to determine which interventions would meet these criteria. RESULTS: Three interventions (social skills training, supported employment and supported housing) have a strong evidence base for effectiveness in early intervention in people with psychosocial disability, with the potential for adoption by the NDIS...
February 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29457248/duty-hours-restriction-for-our-surgical-trainees-an-ethical-obligation-or-a-bad-idea
#2
REVIEW
Christopher A Adin, Callie A Fogle, Steven L Marks
To ensure patient safety and protect the well-being of interns and residents, the Accreditation Council for Graduate Medical Education (ACGME) issued guidelines in 2003 limiting the working hours of physician trainees. Although many supported the goals of the ACGME, institutions struggled to restructure their programs and hire staff required by this unfunded mandate. Numerous studies have analyzed the effects of duty hours restrictions on patient outcomes and physician training over the past 15 years. Most agree that duty hours restrictions improved well-being of house officers, but these improvements came at the expense of continuity, and patient hand-offs led to medical errors...
February 19, 2018: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29453107/body-fluid-identification-using-a-targeted-mrna-massively-parallel-sequencing-approach-results-of-a-euroforgen-ednap-collaborative-exercise
#3
S Ingold, G Dørum, E Hanson, A Berti, W Branicki, P Brito, P Elsmore, K B Gettings, F Giangasparo, T E Gross, S Hansen, E N Hanssen, M-L Kampmann, M Kayser, F-X Laurent, N Morling, A Mosquera-Miguel, W Parson, C Phillips, M J Porto, E Pośpiech, A D Roeder, P M Schneider, K Schulze Johann, C R Steffen, D Syndercombe-Court, M Trautmann, M van den Berge, K J van der Gaag, J Vannier, V Verdoliva, A Vidaki, C Xavier, J Ballantyne, C Haas
In a previous study we presented an assay for targeted mRNA sequencing for the identification of human body fluids, optimised for the Illumina MiSeq/FGx MPS platform. This assay, together with an additional in-house designed assay for the Ion Torrent PGM/S5 platform, was the basis for a collaborative exercise within 17 EUROFORGEN and EDNAP laboratories, in order to test the efficacy of targeted mRNA sequencing to identify body fluids. The task was to analyse the supplied dried body fluid stains and, optionally, participants' own bona fide or mock casework samples of human origin, according to specified protocols...
January 31, 2018: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29451326/evaluation-of-factors-contributing-to-the-decline-in-exclusive-breastfeeding-at-6-months-postpartum-the-2011-2016-national-surveys-in-taiwan
#4
Alexander Waits, Chao-Yu Guo, Li-Yin Chien
BACKGROUND: Since 1992, breastfeeding promotion in Taiwan considerably raised the breastfeeding rates; however, more recent surveillance showed that breastfeeding indicators stagnated or even decreased. METHODS: We analyzed 6 cross-sectional national surveys of 69 159 postpartum women to examine the breastfeeding trends at 6 months postpartum during 2011-2016 in Taiwan and the contributing role of maternal and environmental factors. Data were collected through telephone interviews, using structured questionnaires with randomly selected mothers, who gave birth in those years...
February 16, 2018: Birth
https://www.readbyqxmd.com/read/29450789/control-by-association-transfer-of-implicitly-primed-attentional-states-across-linked-stimuli
#5
Christina Bejjani, Ziwei Zhang, Tobias Egner
Although cognitive control has traditionally been viewed in opposition to associative learning, recent studies show that people can learn to link particular stimuli with specific cognitive control states (e.g., high attentional selectivity). Here, we tested whether such learned stimulus-control associations can transfer across paired-associates. In the Stimulus-Stimulus (S-S) Association phase, specific face or house images repeatedly preceded the presentation of particular scene stimuli, creating paired face/house-scene associates in memory...
February 15, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29449545/transcriptional-repression-of-dna-repair-genes-is-a-hallmark-and-a-cause-of-cellular-senescence
#6
Guillaume Collin, Anda Huna, Marine Warnier, Jean-Michel Flaman, David Bernard
Cellular senescence response is (i) activated by numerous stresses, (ii) is characterized by a stable proliferation arrest, and (iii) by a set of specific features. Timely regulated senescence is thought to be beneficial, whereas chronic senescence such as during normal or premature aging is deleterious as it favors most, if not all, age-related diseases. In this study, using in-house or publicly available microarray analyses of transcriptomes of senescent cells, as well as analyses of the level of expression of several DNA repair genes by RT-qPCR and immunoblot, we show that repression of DNA repair gene expression is associated with cellular senescence...
February 15, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29444154/associations-between-owner-personality-and-psychological-status-and-the-prevalence-of-canine-behavior-problems
#7
Nicholas H Dodman, Dorothy C Brown, James A Serpell
Behavioral problems are a major source of poor welfare and premature mortality in companion dogs. Previous studies have demonstrated associations between owners' personality and psychological status and the prevalence and/or severity of their dogs' behavior problems. However, the mechanisms responsible for these associations are currently unknown. Other studies have detected links between the tendency of dogs to display behavior problems and their owners' use of aversive or confrontational training methods...
2018: PloS One
https://www.readbyqxmd.com/read/29444118/demographic-and-genetic-viability-of-a-medium-sized-ground-dwelling-mammal-in-a-fire-prone-rapidly-urbanizing-landscape
#8
Cristina E Ramalho, Kym M Ottewell, Brian K Chambers, Colin J Yates, Barbara A Wilson, Roberta Bencini, Geoff Barrett
The rapid and large-scale urbanization of peri-urban areas poses major and complex challenges for wildlife conservation. We used population viability analysis (PVA) to evaluate the influence of urban encroachment, fire, and fauna crossing structures, with and without accounting for inbreeding effects, on the metapopulation viability of a medium-sized ground-dwelling mammal, the southern brown bandicoot (Isoodon obesulus), in the rapidly expanding city of Perth, Australia. We surveyed two metapopulations over one and a half years, and parameterized the PVA models using largely field-collected data...
2018: PloS One
https://www.readbyqxmd.com/read/29444092/the-impact-of-early-life-nutrition-and-housing-on-growth-and-reproduction-in-dairy-cattle
#9
G Curtis, C McGregor Argo, D Jones, D Grove-White
Contentious issues in calf rearing include milk feeding practices and single versus group housing. The current study was performed on a high producing 170 Holstein cow dairy farm, to investigate the impact of nutrition and housing on growth and reproduction. Heifer calves (n = 100) were allocated in birth order to one of two commonly used management strategies. All calves received 3-4 litres of dam specific colostrum within 6 hours of birth. Group A calves were group housed from birth and fed milk replacer (MR) ad libitum via a computerised machine utilising a single teat, with weaning commencing at 63 days of age...
2018: PloS One
https://www.readbyqxmd.com/read/29443948/shared-housing-arrangements-in-germany-an-equitable-alternative-to-long-term-care-services-beyond-homes-and-institutions
#10
Lorraine Frisina Doetter, Achim Schmid
Given the saliency of socio-demographic pressures, the highly restrictive definition of "need for care" characterizing the German long-term care system at its foundations in 1994 has since been subject to various expansionary reforms. This has translated into greater interest in innovative care models that provide more choice and flexibility to beneficiaries. One such model is 'shared housing arrangements' ("ambulant betreute Wohngemeinschaften"), where a small group of people rent private rooms, while sharing a common space, domestic support, and nursing care...
February 14, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29441596/responding-to-intimate-partner-violence-healthcare-providers-current-practices-and-views-on-integrating-a-safety-decision-aid-into-primary-care-settings
#11
Carmen Alvarez, Katrina Debnam, Amber Clough, Kamila Alexander, Nancy E Glass
Supportive care for survivors of intimate partner violence (IPV) remains limited in primary care settings. Low-income and Spanish-speaking survivors of IPV are even more disadvantaged, given the dearth of linguistically and culturally appropriate interventions for IPV. We conducted semi-structured individual interviews with 17 healthcare workers, including physicians, nurses, and social workers, to describe how healthcare workers serving primarily low-income, Latina populations are currently screening and responding to IPV disclosure, and to explore the acceptability of integrating an interactive, personalized safety decision aid application-myPlan app-into the clinic setting...
February 14, 2018: Research in Nursing & Health
https://www.readbyqxmd.com/read/29439368/systemic-administration-of-donepezil-attenuates-the-efficacy-of-environmental-enrichment-on-neurobehavioral-outcome-after-experimental-traumatic-brain-injury
#12
Corina O Bondi, Narayana K Yelleswarapu, Julian Day-Cooney, Kimiya Memarzadeh, Kaitlin A Folweiler, Carine E Bou-Abboud, Jacob B Leary, Jeffrey P Cheng, Roya Tehranian-DePasquale, Anthony E Kline
BACKGROUND: The acetylcholinesterase inhibitor (AChEI) donepezil (DON) is recommended as a potential treatment for cognition after clinical traumatic brain injury (TBI) and therefore may be prescribed as an adjunct therapy during rehabilitation. However, a dose-response study evaluating DON after a controlled cortical impact (CCI) injury in rats did not reveal cognitive benefits. OBJECTIVE: The aim of this study was to determine the effect of DON on behavioral and histological outcome when combined with environmental enrichment (EE), a preclinical model of neurorehabilitation...
2018: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/29439325/prediction-and-early-detection-of-alzheimer-s-dementia-professional-disclosure-practices-and-ethical-attitudes
#13
Mark Schweda, Anna Kögel, Claudia Bartels, Jens Wiltfang, Anja Schneider, Silke Schicktanz
BACKGROUND: Biomarker-supported testing for preclinical and prodromal Alzheimer's disease (AD) finds its way into clinical practice. Professional attitudes and practices regarding disclosure and ethical issues are controversial in many countries. OBJECTIVES: Against this background, the objective was to survey the actual practice and the attitudes of physicians in German hospitals and memory clinics in order to explore possible practical insecurities and ethical concerns...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29432786/oleic-acid-induces-the-novel-apolipoprotein-o-and-reduces-mitochondrial-membrane-potential-in-chicken-and-human-hepatoma-cells
#14
Anna M Weijler, Barbara Schmidinger, Stylianos Kapiotis, Hilde Laggner, Marcela Hermann
Non-alcoholic fatty liver disease (NAFLD) is marked by hepatic fat accumulation and reflects a spectrum of chronic liver diseases associated with obesity, impaired insulin sensitivity and dyslipidemia. Apolipoprotein O (ApoO) is a new member of the plasma apolipoprotein family that may play a role in lipid metabolism and electron transport activity of the mitochondrium. However, its physiological functions have not been elucidated yet. Based on our previous data in a non-mammalian experimental system [1], we hypothesized that hepatic expression of ApoO is tightly linked not only to diet-induced hepatosteatosis, but also to increased lipoprotein-production induced by, e...
February 9, 2018: Biochimie
https://www.readbyqxmd.com/read/29431729/development-of-in-house-lattice-boltzmann-simulator-of-bioreactors-for-wastewater-treatment-basic-concepts-and-initial-results
#15
V A Fortunato, F L Caneppele, R Ribeiro, J A Rabi
While computational modelling has increasingly supported wastewater bioreactor engineering, novel numerical techniques have been developed such as the lattice-Boltzmann method (LBM). With vinasse treatment as case study, this work is a first step towards a comprehensive LBM simulator of a continuous-flow anaerobic packed-bed reactor. Extensions from typical models comprise one-dimensional (besides time) dependence, species transport via convection and diffusion, and imposition of either Dirichlet or Danckwerts condition at inlet...
February 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29431216/mast-cell-neural-interactions-contribute-to-pain-and-itch
#16
REVIEW
Kalpna Gupta, Ilkka T Harvima
Mast cells are best recognized for their role in allergy and anaphylaxis, but increasing evidence supports their role in neurogenic inflammation leading to pain and itch. Mast cells act as a "power house" by releasing algogenic and pruritogenic mediators, which initiate a reciprocal communication with specific nociceptors on sensory nerve fibers. Consequently, nerve fibers release inflammatory and vasoactive neuropeptides, which in turn activate mast cells in a feedback mechanism, thus promoting a vicious cycle of mast cell and nociceptor activation leading to neurogenic inflammation and pain/pruritus...
March 2018: Immunological Reviews
https://www.readbyqxmd.com/read/29430136/a-comparative-evaluation-of-fatigue-resistance-of-two-different-implant-overdenture-stud-attachments-with-two-different-denture-base-materials-an-in-vitro-study
#17
Namrata Agrawal, Sumeet Jain, Deepak Agrawal
Introduction: The two implant-supported overdentures have overcome the retention and stability-related problems of conventional mandibular denture. Stud attachments are widely available, less expensive, and easy to use. Aims and Objectives: To determine fatigue resistance of two different stud attachments with two denture base materials - autopolymerizing and heat cure acrylic resin till 4320 cycles simulating 03 years of service. Materials and Methods: Stud implant overdenture attachments, i...
January 2018: Journal of Indian Prosthodontic Society
https://www.readbyqxmd.com/read/29427064/diagnostic-and-prognostic-value-of-amyloid-pet-textural-and-shape-features-comparison-with-classical-semi-quantitative-rating-in-760-patients-from-the-adni-2-database
#18
Fayçal Ben Bouallègue, Fabien Vauchot, Denis Mariano-Goulart, Pierre Payoux
We evaluated the performance of amyloid PET textural and shape features in discriminating normal and Alzheimer's disease (AD) subjects, and in predicting conversion to AD in subjects with mild cognitive impairment (MCI) or significant memory concern (SMC). Subjects from the Alzheimer's Disease Neuroimaging Initiative with available baseline 18F-florbetapir and T1-MRI scans were included. The cross-sectional cohort consisted of 181 controls and 148 AD subjects. The longitudinal cohort consisted of 431 SMC/MCI subjects, 85 of whom converted to AD during follow-up...
February 9, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29426308/quality-of-social-and-emotional-wellbeing-services-for-families-of-young-indigenous-children-attending-primary-care-centers-a-cross-sectional-analysis
#19
Karen M Edmond, Kimberley McAuley, Daniel McAullay, Veronica Matthews, Natalie Strobel, Rhonda Marriott, Ross Bailie
BACKGROUND: The quality of social and emotional wellbeing services for Indigenous families of young children is not known, in many settings especially services provided by primary care centers. METHODS: Our primary objective was to assess delivery of social and emotional wellbeing services to the families of young (3-11 months) and older (12-59 months) Indigenous children attending primary care centers. Our secondary objective was to assess if delivery differed by geographic location...
February 9, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29425378/government-cloud-computing-policies-potential-opportunities-for-advancing-military-biomedical-research
#20
Frank J Lebeda, Jeffrey J Zalatoris, Julia B Scheerer
Introduction: This position paper summarizes the development and the present status of Department of Defense (DoD) and other government policies and guidances regarding cloud computing services. Due to the heterogeneous and growing biomedical big datasets, cloud computing services offer an opportunity to mitigate the associated storage and analysis requirements. Having on-demand network access to a shared pool of flexible computing resources creates a consolidated system that should reduce potential duplications of effort in military biomedical research...
February 7, 2018: Military Medicine
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