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unstably housed

Nick Kerman, John Sylvestre, Tim Aubry, Jino Distasio
BACKGROUND: Housing First is an effective intervention to stably house and alter service use patterns in a large proportion of homeless people with mental illness. However, it is unknown whether there are differences in the patterns of service use over time among those who do or do not become stably housed and what effect, if any, Housing First has on these differing service use patterns. This study explored changes in the service use of people with mental illness who received Housing First compared to standard care, and how patterns of use differed among people who did and did not become stably housed...
March 20, 2018: BMC Health Services Research
Amanda D Castel, Arpi Terzian, Jenevieve Opoku, Lindsey Powers Happ, Naji Younes, Michael Kharfen, Alan Greenberg
BACKGROUND: Triangulation of data from multiple sources such as clinical cohort and surveillance data can help improve our ability to describe care patterns, service utilization, comorbidities, and ultimately measure and monitor clinical outcomes among persons living with HIV infection. OBJECTIVES: The objective of this study was to determine whether linkage of clinical cohort data and routinely collected HIV surveillance data would enhance the completeness and accuracy of each database and improve the understanding of care patterns and clinical outcomes...
March 16, 2018: JMIR Public Health and Surveillance
Renae Furl, Shinobu Watanabe-Galloway, Elizabeth Lyden, Susan Swindells
BACKGROUND: The introduction of the Affordable Care Act (ACA) has provided unprecedented opportunities for uninsured people with HIV infection to access health insurance, and to examine the impact of this change in access. AIDS Drug Assistance Programs (ADAPs) have been directed to pursue uninsured individuals to enroll in the ACA as both a cost-saving strategy and to increase patient access to care. We evaluated the impact of ADAP-facilitated health insurance enrollment on health outcomes, and demographic and clinical factors that influenced whether or not eligible patients enrolled...
March 16, 2018: BMC Infectious Diseases
Sungwoo Lim, Tejinder P Singh, Gerod Hall, Sarah Walters, L Hannah Gould
OBJECTIVE: To assess the impact of a New York City supportive housing program on housing stability and preventable emergency department (ED) visits/hospitalizations among heads of homeless families with mental and physical health conditions or substance use disorders. DATA SOURCES: Multiple administrative data from New York City and New York State for 966 heads of families eligible for the program during 2007-12. STUDY DESIGN: We captured housing events and health care service utilization during 2 years prior to the first program eligibility date (baseline) and 2 years postbaseline...
March 12, 2018: Health Services Research
Lei Zhang, Taiyuan Guan, Ji Qi, Shaoqun Zhang, Xin Zhou, Yang Liu, Shijie Fu
The anterior cruciate ligament (ACL) is an important structure that maintains the stability of knee joints. Animal models of ACL injury are helpful to explore its underlying mechanisms, and strategies for prevention, treatment and rehabilitation. Therefore, the aim of the present study was to develop an efficient model of ACL injury in cynomolgus monkeys via arthroscopic techniques. In the present study, 18 cynomolgus monkeys were randomly divided into a model group (n=6), a sham operation group (n=6) and a blank control group (n=6)...
March 2018: Experimental and Therapeutic Medicine
Christopher J Poronsky, Jingfang Qian Cutrone
In drug discovery research, residual solvent measurement is an integral part of purity analysis for synthesis of a drug candidate before it is used for toxicity testing. This is usually carried out using gas chromatography (GC) with direct injection sample introduction. This method requires testing compounds to be soluble at high concentrations (>50 mg/mL, usually in DMSO) to achieve acceptable sensitivity, a hurdle which is not always achievable for some samples such as cyclic peptides and oligonucleotides...
August 2017: Journal of Pharmaceutical Analysis
Laura Amendolagine, Tad Schoffner, Lynn Koscielny, Mandi Schook, Debra Copeland, James Casteel, Brianna Duff, Diana Koester
Although numbers of giant anteaters within North American facilities have been steadily increasing for the last 15 years, the population now exhibits an unstable age distribution with genetically valuable individuals nearing reproductive senescence. Contributing to this issue is the Association of Zoos and Aquariums (AZA) described lack of standardization of breeding introduction practices and high risk of female injury occurring during such pairings. This report describes the development of a successful breeding protocol at Cleveland Metroparks Zoo based on hormone monitoring and efficient communication between science and animal management teams that minimizes risk of female injury...
January 2018: Zoo Biology
Sofia Salsi, Yara Awadallah, Aurélie B Leclair, Marie-Lyse Breault, Dan-Tam Duong, Laurence Roy
BACKGROUND: Women in unstable housing or who are homeless experience disruptions of occupational engagement and performance. Little is known about their perspective on their occupational needs and priorities. PURPOSE: This study aimed to determine how patterns of occupational engagement and performance are facilitated or hindered by personal factors and resources available to sheltered women. METHOD: A participatory, descriptive mixed-methods study design was used...
October 2017: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
Megan Sandel, Richard Sheward, Stephanie Ettinger de Cuba, Sharon M Coleman, Deborah A Frank, Mariana Chilton, Maureen Black, Timothy Heeren, Justin Pasquariello, Patrick Casey, Eduardo Ochoa, Diana Cutts
OBJECTIVES: To evaluate how 3 forms of housing instability relate to caregiver and child health among low-income renter households. METHODS: Caregivers of children 0 to 48 months of age were interviewed in 5 urban medical centers from May 2009 to December 2015. Caregivers reported on the following: caregiver health, maternal depressive symptoms, child's health, lifetime hospitalizations, developmental risk, and 3 housing circumstances, which were categorized as being behind on rent in the past 12 months, multiple moves (≥ 2 in past 12 months), and child's lifetime history of homelessness...
January 22, 2018: Pediatrics
Barbara L Brush, Laura E Gultekin, Elizabeth B Dowdell, Denise M Saint Arnault, Katherine Satterfield
Although trauma-informed approaches guide services to families experiencing homelessness, more emphasis is placed on securing housing than addressing underlying trauma contributing to housing instability. Examining the stories of 29 homeless and/or unstably housed mothers within the broader literature on family trauma and violence, chronic illness, and cultural aspects of family functioning, we define the process of trauma normativeness and normalization that may occur with repeated trauma experiences and argue that rehousing efforts must include concomitant attention to trauma and to understanding how individual, family, community, and cultural factors influence help-seeking behaviors in this vulnerable and growing population...
November 1, 2017: Violence Against Women
Rebekah A Erickson, Tim Stockwell, Bernadette Pauly, Clifton Chow, Audra Roemer, Jinhui Zhao, Kate Vallance, Ashley Wettlaufer
INTRODUCTION AND AIMS: We investigated coping strategies used by alcohol-dependent and unstably housed people when they could not afford alcohol, and how managed alcohol program (MAP) participation influenced these. The aim of this study was to investigate potential negative unintended consequences of alcohol being unaffordable. DESIGN AND METHODS: A total of 175 MAP residents in five Canadian cities and 189 control participants from nearby shelters were interviewed about the frequency they used 10 coping strategies when unable to afford alcohol...
January 4, 2018: Drug and Alcohol Review
Melissa R Koch, Nealia C M House, Casey M Cosetta, Robyn M Jong, Christelle G Salomon, Cailin E Joyce, Elliot A Philips, Xiaofeng A Su, Catherine H Freudenreich
CAG/CTG trinucleotide repeats are unstable sequences that are difficult to replicate, repair, and transcribe due to their structure-forming nature. CAG repeats strongly position nucleosomes; however, little is known about the chromatin remodeling needed to prevent repeat instability. In a Saccharomyces cerevisiae model system with CAG repeats carried on a YAC, we discovered that the chromatin remodeler Isw1 is required to prevent CAG repeat expansions during transcription. CAG repeat expansions in the absence of Isw1 were dependent on both transcription-coupled repair (TCR) and base-excision repair (BER)...
March 2018: Genetics
Seth A Berkowitz, Sara Kalkhoran, Samuel T Edwards, Utibe R Essien, Travis P Baggett
OBJECTIVE: Homelessness is associated with worse diabetes outcomes, but the relationship between other forms of unstable housing and diabetes is not well studied. We assessed whether unstable housing was associated with increased risk for diabetes-related emergency department use or hospitalization. RESEARCH DESIGN AND METHODS: We used data from the 2014 Health Center Patient Survey, a cross-sectional, nationally representative survey of patients who receive care at federally funded safety-net health centers...
January 4, 2018: Diabetes Care
Kimberly M Nelson, David W Pantalone, Kristi E Gamarel, Michael P Carey, Jane M Simoni
In the United States, gay, bisexual, and other men who have sex with men (GBMSM) are disproportionately affected by the HIV/AIDS epidemic. Despite great strides in HIV prevention, including biobehavioral HIV prevention strategies such as pre-exposure prophylaxis and treatment as prevention, there has been relatively low uptake of these strategies. The success of biobehavioral prevention strategies requires HIV testing but a subset of GBMSM have never been tested. To optimize prevention efforts, we sought to understand the characteristics of GBMSM who report never testing for HIV...
January 2018: AIDS Patient Care and STDs
Meredith C Meacham, Danielle E Ramo, Alex H Kral, Elise D Riley
BACKGROUND: Several studies suggest that U.S. state-level legalization of cannabis for medical purposes may be associated with reductions in opioid use; yet its relationship with stimulant use, particularly in high-risk populations like unstably housed women, has received less attention. The purpose of this study was to estimate independent associations between medical and non-medical use of cannabis and use of stimulants and opioids among unstably housed women. METHODS: Cross-sectional data were analyzed from 245 women in the SHADOW study, a community based cohort in San Francisco, CA, in which HIV+ women were oversampled (126 HIV+ and 119 HIV-)...
February 2018: International Journal on Drug Policy
Aaron Sibley, Kathryn A Dong, Brian H Rowe
Introduction Learners in the emergency department (ED) frequently encounter individuals who are homeless. We sought to evaluate the effect of an inner city emergency medicine rotation at the Royal Alexandra Hospital (RAH) on the attitudes of medical students and residents towards this population. Methods Data were collected both pre- and post-rotation using an electronic survey. Data collected included demographic information and as well as scores on the Health Professionals' Attitudes Towards the Homeless Inventory (HPATHI)...
October 5, 2017: Curēus
Timothy R Ramadhar, Shao-Liang Zheng, Yu-Sheng Chen, Jon Clardy
A strategy that leverages solvent effects to noncovalently trap solid and unstable liquid organic compounds within a crystalline sponge ({[(ZnI2 )3 (tris(4-pyridyl)-1,3,5-triazine)2 ]· x (CHCl3 )}n ) in a simple, mild, and efficient fashion for target molecule structure determination via X-ray diffraction is disclosed. Host-guest structures were obtained using third-generation synchrotron radiation, and new beamline hardware allowed rapid data collection in ~5-24 minutes. This is 40-90% faster than previously reported crystalline sponge synchrotron datasets collected by us, and approximately a 150-720-fold decrease in time versus using a typical in-house diffractometer, effectively enabling the potential for high-throughput analysis...
August 21, 2017: CrystEngComm
Herzl Chai, Adam J Mieleszko, Stephen J Chu, Yu Zhang
OBJECTIVE: Porcelain fused to zirconia (PFZ) restorations are widely used in prosthetic dentistry. However, their tendency to delaminate along the P/Z interface remains a practical problem so that assessing and improving the interfacial strength are important design aspects. This work examines the effect of modifying the zirconia veneering surface with an in-house felspathic glass on the interfacial fracture resistance of fused P/Z. METHODS: Three material systems are studied: porcelain fused to zirconia (control) and porcelain fused to glass-graded zirconia with and without the presence of a glass interlayer...
January 2018: Dental Materials: Official Publication of the Academy of Dental Materials
Sara Nelson Glick, Richard Burt, Kim Kummer, Joe Tinsley, Caleb J Banta-Green, Matthew R Golden
BACKGROUND: In King County, Washington, the HIV prevalence among men who have sex with men (MSM) who inject methamphetamine is high, while it is low among other people who inject drugs (PWID). Local drug problem indicators suggest that methamphetamine use is increasing. The extent to which this increase affects MSM and non-MSM, and whether MSM and non-MSM networks are connected through injection equipment sharing, is unknown. METHODS: We used data from two serial cross-sectional surveys of PWID including five biannual surveys of Public Health-Seattle and King County Needle and Syringe Exchange Program clients (NSEP, N=2135, 2009-2017) and three National HIV Behavioral Surveillance IDU surveys (NHBS, N=1709, 2009-2015)...
January 1, 2018: Drug and Alcohol Dependence
Carla S Ginn, Muhammad Kashif Mughal, Hafsa Syed, Amanda Rae Storteboom, Karen M Benzies
The aim of this mixed-methods study was to investigate attrition at the age 10-year follow-up in a study of vulnerable children and their families living with low income following a two-generation preschool program in Calgary, Alberta, Canada. Quantitative factors associated with attrition included: (a) food bank use; (b) unstable housing; (c) child welfare involvement; (d) unpartnered status; and (e) caregiver noncompletion of high school. Qualitative themes related to attrition included: (a) income and employment; (b) health; (c) unstable housing; (d) change of guardianship; (e) domestic violence; (f) work and time management challenges; and (g) negative caregiver-child relationships...
November 2017: Journal of Family Nursing
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