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https://www.readbyqxmd.com/read/29764962/canadian-rheumatology-association-meeting-february-21-24-2018-introduction-abstracts-author-index
#1
(no author information available yet)
The 73rd Annual Meeting of The Canadian Rheumatology Association (CRA) was held at the JW Marriott Parq Vancouver, Vancouver, British Columbia, Canada, February 21-24, 2018. The program consisted of presentations covering original research, symposia, awards, and lectures.
May 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29762444/efficacy-of-autologous-platelet-concentrates-as-adjuvant-therapy-to-surgical-excision-in-the-treatment-of-keloid-scars-refractory-to-conventional-treatments-a-pilot-prospective-study
#2
Barbara Hersant, Mounia SidAhmed-Mezi, Frédéric Picard, Oana Hermeziu, Anne-Marie Rodriguez, Khaled Ezzedine, Jean Paul Meningaud
BACKGROUND: After conventional treatments, keloid scars show varying degrees of recurrence. The aim of this study was to assess the efficacy and safety of platelet-rich plasma in the treatment of postoperative keloid scars refractory to conventional treatments. METHODS: This pilot prospective study was conducted in 17 patients with keloid scars who did not respond to 4 injections of cortisone or radiotherapy after extralesional resection of keloid. Platelet-rich plasma was injected intraoperatively and then 3 times with a 1-month interval...
May 14, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29757934/comparison-of-synthetic-media-designed-for-expansion-of-adipose-derived-mesenchymal-stromal-cells
#3
Michelle Lensch, Angela Muise, Lisa White, Michael Badowski, David Harris
Mesenchymal stromal cells (MSCs) are multipotent cells that can differentiate into various cell types, such as osteoblasts, myocytes, and adipocytes. This characteristic makes the cells a useful tool in developing new therapies for a number of common maladies and diseases. The utilization of animal-derived growth serum, such as fetal bovine serum (FBS), for the expansion of MSCs has traditionally been used for cell culture. However, in clinical applications, animal-derived products present limitations and safety concerns for the recipient, as exposure to animal (xeno-) antigens and infectious agents is possible...
May 14, 2018: Biomedicines
https://www.readbyqxmd.com/read/29757022/clinical-outcome-of-1064-nm-picosecond-neodymium-doped-yttrium-aluminium-garnet-laser-for-the-treatment-of-hypertrophic-scars
#4
Young-Jun Choi, Jung Yup Kim, Jae-Hui Nam, Ga-Young Lee, Won-Serk Kim
BACKGROUND: Currently no study has evaluated the effect of the novel 1064-nm picosecond neodymium-doped:yttrium aluminium garnet laser (ps-Nd:YAG) for reducing Hypertrophic scarring (HS). OBJECTIVE: The aim of this study was to verify the efficacy and safety of a 1064-nm ps-Nd:YAG in the management of HS. MATERIALS AND METHODS: A retrospective chart review and photographic analysis were conducted on patients treated with a low-fluence 1064-nm ps-Nd:YAG for HS improvement...
May 14, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29743500/clinical-evaluation-of-silicone-gel-in-the-treatment-of-cleft-lip-scars
#5
Chun-Shin Chang, Christopher Glenn Wallace, Yen-Chang Hsiao, Jung-Ju Huang, Zung-Chung Chen, Chee-Jen Chang, Lun-Jou Lo, Philip Kuo-Ting Chen, Jyh-Ping Chen, Yu-Ray Chen
Upper lip scars are at risk of hypertrophy. Our center therefore uses microporous tape and silicone sheeting for postoperative scar care following cleft lip repair. However, some babies have previously ingested their silicone sheeting, which has the potential for respiratory compromise or gastrointestinal obstruction. Self-dry silicone gel is reportedly also effective for preventing hypertrophic scars. Hence, we sought to test whether silicone gel, which cannot be ingested whole, might be non-inferior to silicone sheeting for controlling against upper lip scar hypertrophy...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29739463/trade-offs-fairness-and-funding-for-cancer-drugs-key-findings-from-a-deliberative-public-engagement-event-in-british-columbia-canada
#6
Colene Bentley, Sarah Costa, Michael M Burgess, Dean Regier, Helen McTaggart-Cowan, Stuart J Peacock
BACKGROUND: Spending on cancer drugs has risen dramatically in recent years compared to other areas of health care, due in part to higher prices associated with newly approved drugs and increased demand for these drugs. Addressing this situation requires making difficult trade-offs between cost, harms, and ability to benefit when using public resources, making it important for policy makers to have input from many people affected by the issue, including citizens. METHODS: In September 2014, a deliberative public engagement event was conducted in Vancouver, British Columbia (BC), on the topic of priority setting and costly cancer drugs...
May 8, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29734617/blood-mercury-lead-and-cadmium-levels-and-determinants-of-exposure-among-newcomer-south-and-east-asian-women-of-reproductive-age-living-in-vancouver-canada
#7
Linda Dix-Cooper, Tom Kosatsky
BACKGROUND: Biomarkers of the reproductive and neuro-developmental toxicants mercury (Hg), lead (Pb) and cadmium (Cd) have been found at higher concentrations in women born outside Canada than in Canadian-born women. We measured blood Hg, Pb and Cd in women ages 19 to 45years living in greater Vancouver (Canada) within five years of their arrival from South Asia (India) or East Asia (mainland China, Hong Kong and Taiwan) and related their biomarker concentration levels with exposures and behaviors since their coming to Canada...
April 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29730939/quantifying-patient-reported-disability-and-health-while-waiting-for-bunion-surgery
#8
Jason M Sutherland, Kevin Wing, Murray Penner, Alastair Younger, Guiping Liu, Andrea Veljkovic, Trafford Crump
BACKGROUND: Many patients with hallux valgus progress to experiencing pain and loss of function that requires corrective surgery when nonoperative treatments fail. The primary goal of this study was to measure changes in participants' health while patients waited for their operative correction. METHODS: Patients were prospectively recruited to complete a number of patient-reported outcome measures preoperatively. Baseline data collection was initiated in October 2014, and participants' second surveys were returned by August 2017...
May 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29730777/closed-incision-negative-pressure-therapy-cinpt-reduces-minor-local-complications-in-post-bariatric-abdominoplasty-body-contouring-a-retrospective-case-control-series
#9
Silvio Abatangelo, Elisabetta Saporiti, Giorgio Giatsidis
BACKGROUND: Over 30% of the US population is obese and nearly 300,000 patients undergo bariatric surgery every year. Patients seeking body-contouring procedures face a staggering rate of surgical complications caused by obesity-associated systemic and local factors impairing wound healing. Closed incision negative-pressure therapy (ciNPT) systems could improve surgical outcomes in these patients. Here, we tested this hypothesis in a retrospective case-control series of post-bariatric patients undergoing an abdominoplasty...
May 5, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29728690/publisher-correction-oncolytic-viruses-as-engineering-platforms-for-combination-immunotherapy
#10
Kwame Twumasi-Boateng, Jessica L Pettigrew, Y Y Eunice Kwok, John C Bell, Brad H Nelson
In the online html version of this article, the affiliations for Jessica L. Pettigrew and John C. Bell were not correct. Jessica L. Pettigrew is at the Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada and John C. Bell is at the Center for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. This is correct in the print and PDF versions of the article and has been corrected in the html version.
May 4, 2018: Nature Reviews. Cancer
https://www.readbyqxmd.com/read/29726344/effectiveness-of-theta-burst-versus-high-frequency-repetitive-transcranial-magnetic-stimulation-in-patients-with-depression-three-d-a-randomised-non-inferiority-trial
#11
Daniel M Blumberger, Fidel Vila-Rodriguez, Kevin E Thorpe, Kfir Feffer, Yoshihiro Noda, Peter Giacobbe, Yuliya Knyahnytska, Sidney H Kennedy, Raymond W Lam, Zafiris J Daskalakis, Jonathan Downar
BACKGROUND: Treatment-resistant major depressive disorder is common; repetitive transcranial magnetic stimulation (rTMS) by use of high-frequency (10 Hz) left-side dorsolateral prefrontal cortex stimulation is an evidence-based treatment for this disorder. Intermittent theta burst stimulation (iTBS) is a newer form of rTMS that can be delivered in 3 min, versus 37·5 min for a standard 10 Hz treatment session. We aimed to establish the clinical effectiveness, safety, and tolerability of iTBS compared with standard 10 Hz rTMS in adults with treatment-resistant depression...
April 28, 2018: Lancet
https://www.readbyqxmd.com/read/29724622/improved-outcomes-of-scar-revision-with-the-use-of-polydioxanone-suture-in-comparison-to-polyglactin-910-a-randomized-controlled-trial
#12
Deepti Gupta, Upendra Sharma, Shashank Chauhan, Shamendra Anand Sahu
Scars have multiple cosmetic and functional sequelae, and revision surgeries are an attempt to ameliorate these effects. Reduction of spread of the revised scar is one of the main objectives of revision procedures. Provision of prolonged dermal support to wound can theoretically reduce spread of the scar. We carried out a randomized controlled trial and objectively evaluated the impact of two commonly used absorbable sutures, Polyglactin 910 and Polydioxanone, on scar spread and quality. Sixty patients with post-traumatic scars of 1 year in duration were enrolled in the study and randomly divided into two groups of 30 each...
April 16, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29716387/outcomes-of-vancouver-b2-and-b3-periprosthetic-femoral-fractures-after-total-hip-arthroplasty-in-elderly-patients
#13
Jesús Moreta, Iker Uriarte, Amaia Ormaza, Javier Mosquera, Kattalin Iza, Urko Aguirre, María José Legarreta, José Luis Martínez-De Los Mozos
INTRODUCTION: The objective was to evaluate clinical and radiological outcomes of Vancouver B2 and B3 periprosthetic femoral fractures in patients older than 65 years treated at our institution from 2000 to 2014. We compared the most common methods of fixation: a modular tapered rectangular titanium stem versus a monoblock tapered stem. METHODS: A retrospective review was performed with a minimum follow-up time of 2 years. Patient mobility in the period prior to the fracture and after fracture healing and functional results was assessed according to the Harris Hip Score...
April 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29706256/primary-total-hip-arthroplasty-for-charcot-arthropathy-is-associated-with-high-complications-but-improved-clinical-outcomes
#14
Brian P Chalmers, Meagan E Tibbo, Robert T Trousdale, David G Lewallen, Daniel J Berry, Matthew P Abdel
BACKGROUND: Neuropathic (Charcot) arthropathy of the hip is rare but can lead to joint destruction, bone loss, and dysfunction. While total hip arthroplasty (THA) may be considered a treatment option, only very limited data in the form of case reports are available on the results of THA. The goal of this study was to analyze the outcomes of primary THA for Charcot arthropathy with emphasis on implant survivorship, complications, and clinical outcomes. METHODS: Eleven patients undergoing 12 primary THAs for Charcot arthropathy from 2007 to 2014 were retrospectively reviewed...
April 10, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29701192/-therapeutic-effect-of-mucopolysaccharide-polysulfate-cream-in-prevention-of-postoperative-scars
#15
Qing Zhang, Yixin Zhou, Lina Chen, Yan Xu
To assess the therapeutic effect of mucopolysaccharide polysulfate cream in prevention of postoperative scars.
 Methods: One hundred postoperative patients were divided into an experimental group and a control group (each n=50). After stitch removal, the experimental group wiped mucopolysaccharide polysulfate cream, and the control group wiped urea cream. The scars of the two groups were evaluated by Vancouver Scar Scale (VSS) on the day of stitch removal and in the 4th, 8th, 12th, 16th, 20th, 24th, 28th, and 32th weeks during the treat process...
March 28, 2018: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/29698019/group-based-physical-activity-for-older-adults-goal-randomized-controlled-trial-exercise-adherence-outcomes
#16
Mark R Beauchamp, Geralyn R Ruissen, William L Dunlop, Paul A Estabrooks, Samantha M Harden, Svenja A Wolf, Yan Liu, Toni Schmader, Eli Puterman, A William Sheel, Ryan E Rhodes
BACKGROUND: Despite the health benefits of regular physical activity, across the globe older adults represent the least active section of society. PURPOSE: The GrOup-based physical Activity for oLder adults (GOAL) trial was a three-arm parallel randomized controlled trial (RCT) that was designed to test the efficacy of two group-based exercise programs for older adults, informed by self-categorization theory (SCT), in comparison to a standard group-based exercise program...
May 2018: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/29696168/recruitment-and-retention-of-homeless-individuals-with-mental-illness-in-a-housing-first-intervention-study
#17
Verena Strehlau, Iris Torchalla, Michelle Patterson, Akm Moniruzzaman, Allison Laing, Sindi Addorisio, Jim Frankish, Michael Krausz, Julian Somers
Background: Homeless individuals with mental illness are challenging to recruit and retain in longitudinal research studies. The present study uses information from the Vancouver site of a Canadian multi-city longitudinal randomized controlled trial on housing first interventions for homeless individuals. We were able to recruit 500 participants and retain large number of homeless individuals with mental illness; 92% of the participants completed the 6-month follow up interview, 84% the 24-month follow up, while 80% completed all follow-up visits of the study...
September 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29681159/bullous-pemphigoid-a-10-year-study-of-discordant-results-on-direct-immunofluorescence
#18
Jessica G Fudge, Richard I Crawford
BACKGROUND: Bullous pemphigoid (BP) is the most common subepidermal autoimmune disorder characterized by tense bullae. It is associated with circulating autoantibodies against BP antigen-1 and BP antigen-2. Diagnosis is based upon clinical, histopathologic, and immunopathologic examination. Direct immunofluorescence (DIF) of perilesional skin highlights C3 with or without IgG in a linear pattern along the basement membrane. OBJECTIVES: We hypothesized that repeat biopsies may be required for a definitive DIF diagnosis of BP, as initial DIF evaluation may result in a false-negative result...
April 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29678374/feasibility-of-a-new-v-shaped-incision-for-parotidectomy-a-preliminary-report
#19
D Ahn, J H Sohn, G J Lee
We report the design of a new V-shaped incision for parotidectomy that involves only preauricular and postauricular incisions and no hairline or upper cervical incision. It can be used to approach almost all the superficial parotid region, including the superior and anterior divisions, with minimal scarring. To evaluate its technical feasibility, safety, and cosmetic results, we prospectively enrolled 15 patients (between September 2015 and September 2016) who had partial parotidectomy as the primary treatment for benign parotid tumours...
April 17, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29673814/assessment-of-hair-cortisol-as-a-potential-biomarker-for-possible-adrenal-suppression-due-to-inhaled-corticosteroid-use-in-children-with-asthma-a-retrospective-observational-study
#20
Laura Smy, Kaitlyn Shaw, Ursula Amstutz, Michelle Staub, Shahnaz Chaudhry, Anne Smith, Bruce Carleton, Gideon Koren
BACKGROUND: Inhaled corticosteroids (ICS) are the recommended long-term control therapy for asthma in children. However, concern exists regarding potential adrenal suppression with chronic ICS use. Our pilot study reported that hair cortisol in children was 50% lower during ICS therapy than prior to therapy, suggestive of adrenal suppression. OBJECTIVE: To evaluate hair cortisol concentration (HCC) as a potential biomarker for possible adrenal suppression from ICS use in children with asthma...
April 16, 2018: Clinical Biochemistry
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