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https://www.readbyqxmd.com/read/28110460/ability-of-rf5-and-rf6-to-restore-fertility-of-chinsurah-boro-ii-type-cytoplasmic-male-sterile-oryza-sativa-ssp-japonica-lines
#1
Honggen Zhang, Jianlan Che, Yongshen Ge, Yan Pei, Lijia Zhang, Qiaoquan Liu, Minghong Gu, Shuzhu Tang
BACKGROUND: Three-line Oryza sativa (ssp. japonica) hybrids have been developed mainly using Chinsurah Boro II (BT)-type cytoplasmic male sterility (CMS). The Rf1 gene restores the fertility of BT-type CMS lines, and is the only fertility restorer gene (Rf) that has been used to produce three-line japonica hybrids. Using more Rf genes to breed BT-type restorer lines may broaden the genetic diversity of the restorer lines, and represents a viable approach to improve the heterosis level of BT-type japonica hybrids...
December 2017: Rice
https://www.readbyqxmd.com/read/28110430/ontological-issues-and-the-possible-development-of-cultural-psychology
#2
Gilberto Pérez-Campos
Ontological issues have a bad reputation within mainstream psychology. This paper, however, is an attempt to argue that ontological reflection may play an important role in the development of cultural psychology. A cross-reading of two recent papers on the subject (Mammen & Mironenko, Integrative Psychological and Behavioral Science, 49(4), 681-713, 2015; Simão Integrative Psychological and Behavioral Science, 50, 568-585, 2016), aimed at characterizing their respective approaches to ontological issues, sets the stage for a presentation of Cornelius Castoriadis' ontological reflections...
January 21, 2017: Integrative Psychological & Behavioral Science
https://www.readbyqxmd.com/read/28110406/simultaneous-spatio-temporal-matching-pursuit-decomposition-of-evoked-brain-responses-in-meg
#3
Paweł Kordowski, Artur Matysiak, Reinhard König, Cezary Sielużycki
We present a novel approach to the spatio-temporal decomposition of evoked brain responses in magnetoencephalography (MEG) aiming at a sparse representation of the underlying brain activity in terms of spatio-temporal atoms. Our approach is characterized by three attributes which constitute significant improvements with respect to existing approaches: (1) the spatial and temporal decomposition is addressed simultaneously rather than sequentially, with the benefit that source loci and corresponding waveforms can be unequivocally allocated to each other, and, hence, allow a plausible physiological interpretation of the parametrized data; (2) it is free from severe a priori assumptions about the solution space; (3) it comprises an optimization technique for the use of very large spatial and temporal subdirectories to greatly reduce the otherwise enormous computational cost by making use of the Cauchy-Schwarz inequality...
January 21, 2017: Biological Cybernetics
https://www.readbyqxmd.com/read/28110394/chimeric-antigen-receptor-car-t-cells-lessons-learned-from-targeting-of-cd19-in-b-cell-malignancies
#4
Kevin A Hay, Cameron J Turtle
Adoptive immunotherapy with chimeric antigen receptor-modified (CAR)-T cells is a rapidly growing therapeutic approach to treating patients with refractory cancer, with over 100 clinical trials in various malignancies in progress. The enthusiasm for CAR-T cells has been driven by the clinical success of CD19-targeted CAR-T cell therapy in B-cell acute lymphoblastic leukemia, and the promising data in B-cell non-Hodgkin's lymphoma and chronic lymphocytic leukemia. Despite the success of targeting CD19 with CAR-T cells in early clinical studies, many challenges remain to improve outcomes, reduce toxicity, and determine the appropriate settings for CAR-T cell immunotherapy...
January 21, 2017: Drugs
https://www.readbyqxmd.com/read/28110390/operative-treatment-of-lateral-ligament-instability
#5
REVIEW
Rachel J Shakked, Sydney Karnovsky, Mark C Drakos
PURPOSE OF REVIEW: Ankle sprains, which account for 40% of sports injuries in the USA, can lead to chronic ankle instability. Chronic ankle instability can be classified as functional, mechanical, or a combination of both and is diagnosed using a combination of a physical exam, an MRI, and stress radiographs. This review focuses on different approaches to treatment, including non-operative and operative techniques, of chronic ankle instability, including reviewing traditional procedures as well as more novel and newer techniques...
January 21, 2017: Current Reviews in Musculoskeletal Medicine
https://www.readbyqxmd.com/read/28110373/experiences-with-surgically-treated-primary-or-secondary-hepatic-sarcoma
#6
René Fahrner, Sandra G C Dennler, Felix Dondorf, Michael Ardelt, Falk Rauchfuss, Utz Settmacher
PURPOSE: Liver resection in hepatic sarcoma is rare, but other alternative treatment options are scarce. Surgery offers the only aggressive approach to achieve a tumour-free state. The aim of this investigation was to evaluate the outcome and survival of these patients at a single hepato-biliary university hospital. METHODS: Between January 2004 and July 2013, 896 anatomical liver resections were performed. Eleven liver resections (1.2%) were performed due to primary hepatic sarcoma or hepatic sarcoma metastases...
January 21, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28110204/new-classification-of-epilepsy-related-neoplasms-the-clinical-perspective
#7
REVIEW
Burkhard S Kasper, Ekkehard M Kasper
Neoplastic CNS lesions are a common cause of focal epilepsy refractory to anticonvulsant treatment, i.e. long-term epilepsy-associated tumors (LEATs). Epileptogenic tumors encompass a variety of intriguing lesions, e.g. dysembryoplastic neuroepithelial tumors or gangliogliomas, which differ from more common CNS neoplasms in their clinical context as well as on histopathology. Long-term epilepsy-associated tumor classification is a rapidly evolving issue in surgical neuropathology, with new entities still being elucidated...
January 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28110121/s100a12-friend-or-foe-in-pulmonary-tuberculosis
#8
Vahid Bagheri
In humans, S100A12 (also named Calgranulin C and EN-RAGE) is mainly expressed and secreted by neutrophil granulocytes. Extracellular S100A12 is involved in innate immune responses against microorganisms and parasites. S100A12 is a ligand for the receptor for advanced glycation end products (RAGE), which is a cell surface receptor on macrophages, endothelium, and lymphocytes. In a recent study, Realegeno et al. showed that S100A12 exerts antimicrobial activity against Mycobacterium leprae in infected human macrophages...
January 18, 2017: Cytokine
https://www.readbyqxmd.com/read/28110071/living-nano-micro-fibrous-woven-fabric-hydrogel-composite-scaffolds-for-heart-valve-engineering
#9
Shaohua Wu, Bin Duan, Xiaohong Qin, Jonathan T Butcher
: Regeneration and repair of injured or diseased heart valves remains a clinical challenge. Tissue engineering provides a promising treatment approach to facilitate living heart valve repair and regeneration. Three-dimensional (3D) biomimetic scaffolds that possess heterogeneous and anisotropic features that approximate those of native heart valve tissue are beneficial to the successful in vitro development of tissue engineered heart valves (TEHV). Here we report the development and characterization of a novel composite scaffold consisting of nano- and micro-scale fibrous woven fabrics and 3D hydrogels by using textile techniques combined with bioactive hydrogel formation...
January 18, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28110065/stochasticity-heterogeneity-and-variance-in-longevity-in-human-populations
#10
Nienke Hartemink, Trifon I Missov, Hal Caswell
Inter-individual variance in longevity (or any other demographic outcome) may arise from heterogeneity or from individual stochasticity. Heterogeneity refers to differences among individuals in the demographic rates experienced at a given age or stage. Stochasticity refers to variation due to the random outcome of demographic rates applied to individuals with the same properties. The variance due to individual stochasticity can be calculated from a Markov chain description of the life cycle. The variance due to heterogeneity can be calculated from a multistate model that incorporates the heterogeneity...
January 18, 2017: Theoretical Population Biology
https://www.readbyqxmd.com/read/28110056/current-knowledge-and-management-of-hypersensitivity-reactions-to-monoclonal-antibodies
#11
Matthieu Picard, Violeta Régnier Galvão
Hypersensitivity reactions (HSRs) to monoclonal antibodies (mAbs) are increasingly frequent as this class of therapeutic agents is rapidly expanding. Immediate and nonimmediate HSRs have been reported with mAbs. Immediate HSRs can be explained by 3 main mechanisms: cytokine release syndrome, IgE-mediated, and IgG-mediated reactions. Importantly, IgE-mediated reactions can occur on first exposure due to preformed specific IgEs, as shown for cetuximab. Almost all patients with an immediate HSR can be safely re-exposed either through desensitization or challenge depending on the severity and mechanism of the initial reaction...
January 18, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28110032/first-experience-open-small-incision-rectus-sheath-approach-renal-transplant-a-case-series
#12
Stephen H Phillips, Sharon K Hill, Lorie D Lipscomb, Joseph B Africa
BACKGROUND: Prevention of wound complications is an important goal in surgery, and reduction of modifiable risks factors are an important step towards protecting patients from further complications. Renal transplantation has sought to be more inclusive giving access to transplantation to complex patient populations, many of which have an increased risk of complications. Surgical techniques continue to advance and may contribute to reducing complications. We hypothesized that the Anterior Rectus Sheath (ARS) Approach would provide an open transplant with minimal damage and less wound complications, including fluid collections such as lymphoceles, when compared to the conventional technique (CON) with equivocal graft function and survival...
January 18, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28110025/do-the-complications-increased-in-the-anterolateral-right-side-approach-to-treat-the-cervical-degenerative-disorders
#13
Zhaoyu Ba, Fumin Pan, Xiaoming Liu, Jianguang Zhu, Desheng Wu
The dysphagia and recurrent laryngeal nerve (RLN) palsy are the most common complications of the patients who underwent anterior cervical surgery in the current literature. These morbidities have led to the study of the impact of sidedness in anterior cervical spine surgery. However, many reports documented the left-side was more effective and safe than right-side based on the anatomy. So the right-side approach is more challenging. We retrospectively study 503 patients with cervical degenerative diseases who underwent cervical spinal surgery using anterolateral right-side approach in our spine center from September 1999 to December 2012 and evaluate the efficient and safety of the anterolateral right-side approach to treat the cervical degenerative diseases...
January 18, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28110007/human-health-and-ecological-assessment-programs-for-hebei-spirit-oil-spill-accident-of-2007-status-lessons-and-future-challenges
#14
Dawoon Jung, Jung-Ah Kim, Myung-Sook Park, Un Hyuk Yim, Kyungho Choi
Hebei Spirit oil spill (HSOS) of December 2007 is one of the worst oil spill accidents that occurred in Yellow Sea. The affected coastline along the west coast of Korean Peninsula hosts one of the largest tidal flats worldwide, and is home to tens of thousands of human residents. Based on nation-wide concerns on ecosystem damages and adverse human health effects, two separate surveillance programs on ecosystem and human health were initiated: a 10-year follow-up program by Ministry of Oceans and Fisheries to assess ecological impacts of the oil spill, and an exposure and health effect assessment program by Ministry of Environment for the residents of Taean and its vicinity...
January 2, 2017: Chemosphere
https://www.readbyqxmd.com/read/28109758/the-use-of-electronic-sensor-device-to-augment-ligament-balancing-leads-to-a-lower-rate-of-arthrofibrosis-after-total-knee-arthroplasty
#15
Jeffrey A Geller, Akshay Lakra, Taylor Murtaugh
BACKGROUND: Total knee arthroplasty (TKA) is a highly successful surgery shown to improve quality of life. One of the more common known complications of TKA is early arthrofibrosis requiring manipulation under anesthesia (MUA). This investigation evaluates the incidence of arthrofibrosis before and after the implementation of an electronic sensor device used to assist with ligament balancing. METHODS: Six hundred ninety TKAs performed without sensor use were compared to a cohort of 252 TKAs performed with sensor usage...
December 24, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28109659/fighting-for-the-web-competition-between-female-feather-legged-spiders-uloborus-plumipes
#16
Anna-Christin Joel, Anne Habedank, Jonas Hausen, Jörg Mey
Most spider species are solitary, and among the few social interactions among them, resource competition between females has received little attention. We discovered that females of the feather-legged spider Uloborus plumipes invade the orb webs of conspecifics and compete for webs. Following observations in the wild, intruder-defender interactions were studied in a terrarium and in controlled laboratory experiments. We found that contests for orb webs occurred spontaneously between adult females. Competitive interactions in U...
December 14, 2016: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/28109540/what-will-donald-trump-s-presidency-mean-for-health-a-scorecard
#17
Martin McKee, Scott L Greer, David Stuckler
US Presidents make their mark on health, for better or worse. Donald Trump campaigned on a populist platform to "make America great again". While the actual policies his administration will pursue-and the priority he will place on each of them-remain in many ways uncertain, both his statements and his nominations for key government posts suggest that his presidency could have profound implications for health. His proposal to repeal and replace the Affordable Care Act with a "better reform", his stance on reproductive rights, and his approaches to other areas, such as science policy and climate change, coupled with his stated intention to put "America first" are creating anxiety and uncertainty about America's domestic health policies and its global leadership role in areas such as security and development...
January 18, 2017: Lancet
https://www.readbyqxmd.com/read/28109403/total-antioxidant-capacity-in-beta-thalassemia-a-systematic-review-and-meta-analysis-of-case-control-studies
#18
REVIEW
Husseen Manafikhi, Gregor Drummen, Maura Palmery, Ilaria Peluso
Total Antioxidant Capacity (TAC), a biomarker measuring the antioxidant potential of body fluids, including redox synergistic interactions, is influenced by the presence of products of catabolism such as bilirubin (BR) and uric acid (UA). Hyperuricaemia and increased BR levels were observed in thalassemia. In order to evaluate the differences in TAC values between thalassemic patients and healthy subjects, we performed a systematic review and meta-analysis of case-control studies. After the exclusion of data deemed unsuitable for meta-analysis inclusion and a study imputed of bias by Trim-and-fill analysis, mean difference (MD) and confidence intervals 95% (CI 95%) were calculated by the random effect model for beta-thalassemia major (BTM) (1351 subjects: 770 thalassemic and 581 controls, from 15 studies) and Trait (BTT) or Hemoglobin E (BTE) (475 subjects: 165 thalassemic and 310 controls, from 5 studies)...
February 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28109334/searching-for-the-second-r-in-sexual-and-reproductive-health-and%C3%A2-%C3%A2-rights
#19
Luisa Orza, Tyler Crone, Julie Mellin, Nienke Westerhof, Lucy Stackpool-Moore, Enrique Restoy, Greg Gray, Jacqui Stevenson
Sexual and reproductive health and rights have gained prominence in the HIV response. The role of sexual and reproductive health in underpinning a successful approach to HIV prevention, treatment, care, and services has increasingly been recognized. However, the "second R," referring to sexual and reproductive rights, is often neglected. This leads to policies and programs which both fail to uphold and fulfill these rights and which fail to meet the needs of those most affected by HIV by neglecting to take account of the human right-based barriers and challenges they face...
February 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28109275/insights-of-health-district-managers-on-the-implementation-of-primary-health-care-outreach-teams-in-johannesburg-south-africa-a-descriptive-study-with-focus-group-discussions
#20
Shabir Moosa, Anselme Derese, Wim Peersman
BACKGROUND: Primary health care (PHC) outreach teams are part of a policy of PHC re-engineering in South Africa. It attempts to move the deployment of community health workers (CHWs) from vertical programmes into an integrated generalised team-based approach to care for defined populations in municipal wards. There has little evaluation of PHC outreach teams. Managers' insights are anecdotal. METHODS: This is descriptive qualitative study with focus group discussions with health district managers of Johannesburg, the largest city in South Africa...
January 21, 2017: Human Resources for Health
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