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https://www.readbyqxmd.com/read/27897013/harnessing-big-data-for-precision-medicine-infrastructures-and-applications
#1
Kun-Hsing Yu, Steven N Hart, Rachel Goldfeder, Qiangfeng Cliff Zhang, Stephen C J Parker, Michael Snyder
Precision medicine is a health management approach that accounts for individual differences in genetic backgrounds and environmental exposures. With the recent advancements in high-throughput omics profiling technologies, collections of large study cohorts, and the developments of data mining algorithms, big data in biomedicine is expected to provide novel insights into health and disease states, which can be translated into personalized disease prevention and treatment plans. However, petabytes of biomedical data generated by multiple measurement modalities poses a significant challenge for data analysis, integration, storage, and result interpretation...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/27867450/preserving-patient-privacy-when-sharing-same-disease-data
#2
Xiaoping Liu, Xiao-Bai Li, Luvai Motiwalla, Wenjun Li, Hua Zheng, Patricia D Franklin
Medical and health data are often collected for studying a specific disease. For such same-disease microdata, a privacy disclosure occurs as long as an individual is known to be in the microdata. Individuals in same-disease microdata are thus subject to higher disclosure risk than those in microdata with different diseases. This important problem has been overlooked in data-privacy research and practice, and no prior study has addressed this problem. In this study, we analyze the disclosure risk for the individuals in same-disease microdata and propose a new metric that is appropriate for measuring disclosure risk in this situation...
October 2016: ACM Journal of Data and Information Quality
https://www.readbyqxmd.com/read/27806923/it-s-time-for-innovation-in-the-health-insurance-portability-and-accountability-act-hipaa
#3
Karen Colorafi, Bryan Bailey
Whether it is the result of a tragic news story, a thoughtful commentary, or a segment on the entertainment networks, patient privacy rights are never far from the top of our minds. The Privacy and Security Rules contained in the Health Insurance Portability and Accountability Act of 1996 (HIPAA) represent a concerted effort to protect the privacy and security of the volumes of patient data generated by the health care system. However, the last twenty years has seen innovations and advancements in health information technology that were unimaginable at that time...
November 2, 2016: JMIR Medical Informatics
https://www.readbyqxmd.com/read/27787295/examination-of-an-electronic-patient-record-display-method-to-protect-patient-information-privacy
#4
Yukari Niimi, Katsumasa Ota
Electronic patient records facilitate the provision of safe, high-quality medical care. However, because personnel can view almost all stored information, this study designed a display method using a mosaic blur (pixelation) to temporarily conceal information patients do not want shared. This study developed an electronic patient records display method for patient information that balanced the patient's desire for personal information protection against the need for information sharing among medical personnel...
October 25, 2016: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/27781485/big-data-in-radiation-therapy-challenges-and-opportunities
#5
Tim Lustberg, Johan van Soest, Arthur Jochems, Timo Deist, Yvonka van Wijk, Sean Walsh, Philippe Lambin, Andre Dekker
Data collected and generated by radiation oncology can be classified by the 4Vs of Big Data (Volume, Variety, Velocity, and Veracity) because it is spread across different care providers and not easily shared due to patient privacy protection. The magnitude of the 4Vs is substantial in oncology, especially due to imaging modalities and unclear data definitions. To create useful models ideally all data of all care providers is understood and learned from, however this presents challenges in the guise of poor data quality, patient privacy concerns, geographical spread, interoperability, and the large volume...
October 26, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27763999/electronic-health-e-health-emerging-role-in-asthma
#6
Matteo Bonini
PURPOSE OF REVIEW: Asthma is the most prevalent chronic respiratory disease and represents a relevant socioeconomic burden. e-Health has the potential to improve disease control and adherence to treatment in asthmatic patients. Available data are, however, scarce and inconsistent limiting the use of e-health in clinical practice. This article aims to provide a systematic review of the literature published in the last year regarding the real place and impact of e-health in the management of asthma...
January 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/27722981/access-control-and-privilege-management-in-electronic-health-record-a-systematic-literature-review
#7
Manoj Jayabalan, Thomas O'Daniel
This study presents a systematic literature review of access control for electronic health record systems to protect patient's privacy. Articles from 2006 to 2016 were extracted from the ACM Digital Library, IEEE Xplore Digital Library, Science Direct, MEDLINE, and MetaPress using broad eligibility criteria, and chosen for inclusion based on analysis of ISO22600. Cryptographic standards and methods were left outside the scope of this review. Three broad classes of models are being actively investigated and developed: access control for electronic health records, access control for interoperability, and access control for risk analysis...
December 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/27702792/how-can-hospitals-better-protect-the-privacy-of-electronic-medical-records-perspectives-from-staff-members-of-health-information-management-departments
#8
Ming-Ling Sher, Paul C Talley, Tain-Junn Cheng, Kuang-Ming Kuo
PURPOSE: The adoption of electronic medical records (EMR) is expected to better improve overall healthcare quality and to offset the financial pressure of excessive administrative burden. However, safeguarding EMR against potentially hostile security breaches from both inside and outside healthcare facilities has created increased patients' privacy concerns from all sides. The aim of our study was to examine the influencing factors of privacy protection for EMR by healthcare professionals...
October 4, 2016: HIM Journal
https://www.readbyqxmd.com/read/27614610/how-well-are-we-respecting-patient-privacy-in-medical-imaging-lessons-learnt-from-a-departmental-audit
#9
Marc Dilauro, Rebecca Thornhill, Najla Fasih
RATIONALE AND OBJECTIVES: Preservation of patient privacy and dignity are basic requirements for all patients visiting a hospital. The purpose of this study was to perform an audit of patients' satisfaction with privacy whilst in the Department of Medical Imaging (MI) at the Civic Campus of the Ottawa Hospital. MATERIALS AND METHODS: Outpatients who underwent magnetic resonance imaging (MRI), computed tomography (CT), ultrasonography (US), and plain film (XR) examinations were provided with a survey on patient privacy...
September 7, 2016: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/27613791/implementation-of-technology-based-patient-engagement-strategies-within-practice-based-research-networks
#10
Beth Careyva, Kyle Shaak, Geoffrey Mills, Melanie Johnson, Samantha Goodrich, Brian Stello, Lorraine S Wallace
BACKGROUND: Technology-based patient engagement strategies (such as patient portals) are increasingly available, yet little is known about current use and barriers within practice-based research networks (PBRNs). PBRN directors have unique opportunities to inform the implementation of patient-facing technology and to translate these findings into practice. METHODS: PBRN directors were queried regarding technology-based patient engagement strategies as part of the 2015 CAFM Educational Research Alliance (CERA) survey of PBRN directors...
September 2016: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/27593185/quantifying-disease-activity-in-fatty-infiltrated-skeletal-muscle-by-ideal-cpmg-in-duchenne-muscular-dystrophy
#11
Ami Mankodi, Courtney A Bishop, Sungyoung Auh, Rexford D Newbould, Kenneth H Fischbeck, Robert L Janiczek
The purpose of this study was to explore the use of iterative decomposition of water and fat with echo asymmetry and least-squares estimation Carr-Purcell-Meiboom-Gill (IDEAL-CPMG) to simultaneously measure skeletal muscle apparent fat fraction and water T2 (T2,w) in patients with Duchenne muscular dystrophy (DMD). In twenty healthy volunteer boys and thirteen subjects with DMD, thigh muscle apparent fat fraction was measured by Dixon and IDEAL-CPMG, with the IDEAL-CPMG also providing T2,w as a measure of muscle inflammatory activity...
October 2016: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/27577394/a-generic-method-for-assessing-the-quality-of-de-identified-health-data
#12
Fabian Prasser, Raffael Bild, Klaus A Kuhn
Data sharing plays an important role in modern biomedical research. Due to the inherent sensitivity of health data, patient privacy must be protected. De-identification means to transform a dataset in such a way that it becomes extremely difficult for an attacker to link its records to identified individuals. This can be achieved with different types of data transformations. As transformation impacts the information content of a dataset, it is important to balance an increase in privacy with a decrease in data quality...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/27577361/evaluation-of-secure-computation-in-a-distributed-healthcare-setting
#13
Eizen Kimura, Koki Hamada, Ryo Kikuchi, Koji Chida, Kazuya Okamoto, Shirou Manabe, Tomohiko Kuroda, Yasushi Matsumura, Toshihiro Takeda, Naoki Mihara
Issues related to ensuring patient privacy and data ownership in clinical repositories prevent the growth of translational research. Previous studies have used an aggregator agent to obscure clinical repositories from the data user, and to ensure the privacy of output using statistical disclosure control. However, there remain several issues that must be considered. One such issue is that a data breach may occur when multiple nodes conspire. Another is that the agent may eavesdrop on or leak a user's queries and their results...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/27565509/healthcare-data-gateways-found-healthcare-intelligence-on-blockchain-with-novel-privacy-risk-control
#14
Xiao Yue, Huiju Wang, Dawei Jin, Mingqiang Li, Wei Jiang
Healthcare data are a valuable source of healthcare intelligence. Sharing of healthcare data is one essential step to make healthcare system smarter and improve the quality of healthcare service. Healthcare data, one personal asset of patient, should be owned and controlled by patient, instead of being scattered in different healthcare systems, which prevents data sharing and puts patient privacy at risks. Blockchain is demonstrated in the financial field that trusted, auditable computing is possible using a decentralized network of peers accompanied by a public ledger...
October 2016: Journal of Medical Systems
https://www.readbyqxmd.com/read/27550566/pathology-image-sharing-on-social-media-recommendations-for-protecting-privacy-while-motivating-education
#15
Genevieve M Crane, Jerad M Gardner
There is a rising interest in the use of social media by pathologists. However, the use of pathology images on social media has been debated, particularly gross examination, autopsy, and dermatologic condition photographs. The immediacy of the interactions, increased interest from patients and patient groups, and fewer barriers to public discussion raise additional considerations to ensure patient privacy is protected. Yet these very features all add to the power of social media for educating other physicians and the nonmedical public about disease and for creating better understanding of the important role of pathologists in patient care...
2016: AMA Journal of Ethics
https://www.readbyqxmd.com/read/27538685/ethical-considerations-surrounding-the-response-to-ebola-the-spanish-experience
#16
Miguel Ángel Royo-Bordonada, Fernando J García López
BACKGROUND: The recent Ebola virus disease (EVD) outbreak, with 28,646 reported cases and 11,323 deaths, was declared a public health emergency of international interest by the World Health Organisation. In Spain, a single reported case triggered a public health crisis of a markedly media-centred nature. The approach to the first EVD epidemic has given rise to various ethical considerations around the world. We address the most relevant ethical considerations emanating from the management of EVD in Spain...
2016: BMC Medical Ethics
https://www.readbyqxmd.com/read/27535360/the-biorepository-portal-toolkit-an-honest-brokered-modular-service-oriented-software-tool-set-for-biospecimen-driven-translational-research
#17
Alex S Felmeister, Aaron J Masino, Tyler J Rivera, Adam C Resnick, Jeffrey W Pennington
BACKGROUND: High throughput molecular sequencing and increased biospecimen variety have introduced significant informatics challenges for research biorepository infrastructures. We applied a modular system integration approach to develop an operational biorepository management system. This method enables aggregation of the clinical, specimen and genomic data collected for biorepository resources. METHODS: We introduce an electronic Honest Broker (eHB) and Biorepository Portal (BRP) open source project that, in tandem, allow for data integration while protecting patient privacy...
2016: BMC Genomics
https://www.readbyqxmd.com/read/27518659/sharing-data-from-cardiovascular-clinical-trials-a-proposal
#18
Manesh R Patel, Paul W Armstrong, Deepak L Bhatt, Eugene Braunwald, A John Camm, Keith A A Fox, Robert A Harrington, William R Hiatt, Stefan K James, Ajay J Kirtane, Martin B Leon, A Michael Lincoff, Kenneth W Mahaffey, Laura Mauri, Roxana Mehran, Shamir R Mehta, Gilles Montalescot, Stephen J Nicholls, Vlado Perkovic, Eric D Peterson, Stuart J Pocock, Matthew T Roe, Marc S Sabatine, Mikkael Sekeres, Scott D Solomon, Gabriel Steg, Gregg W Stone, Frans Van de Werf, Lars Wallentin, Harvey D White, Michael Gibson
Participants in clinical research volunteer in order to support the development of scientific knowledge and help future patients. Inherent in their commitment is the belief that research will lead to new insights that will be disseminated. As clinical researchers, we fully support the concept of..
August 4, 2016: New England Journal of Medicine
https://www.readbyqxmd.com/read/27509732/-security-management-in-clinical-laboratory-departments-and-facilities-current-status-and-issues
#19
Haku Ishida, Junji Nakamura, Hiroshi Yoshida, Masaru Koike, Yuji Inoue
We conducted a questionnaire survey regarding the current activities for protecting patients' privacy and the security of information systems (IS) related to the clinical laboratory departments of university hospitals, certified training facilities for clinical laboratories, and general hospitals in Yamaguchi Prefecture. The response rate was 47% from 215 medical institutions, including three commercial clinical laboratory centers. The results showed that there were some differences in management activities among facilities with respect to continuing education, the documentation or regulation of operational management for paper records, electronic information, remaining samples, genetic testing, and laboratory information for secondary use...
November 2014: Rinsho Byori. the Japanese Journal of Clinical Pathology
https://www.readbyqxmd.com/read/27477933/survival-probability-in-patients-with-liver-trauma
#20
Skender Buci, Agim Kukeli
Purpose - The purpose of this paper is to assess the survival probability among patients with liver trauma injury using the anatomical and psychological scores of conditions, characteristics and treatment modes. Design/methodology/approach - A logistic model is used to estimate 173 patients' survival probability. Data are taken from patient records. Only emergency room patients admitted to University Hospital of Trauma (former Military Hospital) in Tirana are included. Data are recorded anonymously, preserving the patients' privacy...
August 8, 2016: International Journal of Health Care Quality Assurance
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