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https://www.readbyqxmd.com/read/28210455/morphea-en-coup-de-sabre-an-unusual-oral-presentation
#1
Sven Niklander, Constanza Marín, René Martínez, Alfredo Esguep
Morphea, or localized scleroderma, is an inflammatory disease that leads to sclerosis of the skin and underlying tissues due to excessive collagen deposition. Oral involvement is unusual and it may produce white linear fibrotic areas with a scar-like appearance, atrophy of tongue papillae, gingival recession and alveolar bone resorption. We report a case of a 13-year-old girl who consulted for progressive recession on the attached gingiva of her upper left incisors. She also presented a hypopigmented line on the left side skin of her upper lip, which continued through the vermilion and the lip mucosa, including the gingiva of the affected teeth...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28209456/the-role-of-stereotactic-ablative-body-radiotherapy-in-gynaecological-cancers-a-systematic-review
#2
L C Mendez, E Leung, P Cheung, L Barbera
AIMS: To summarise and evaluate the current literature in gynaecological tumours treated with stereotactic ablative body radiotherapy (SABR) through a systematic review using the Preferred Reported Items for Systematic Reviews and Meta-analysis (PRISMA) guideline. MATERIALS AND METHODS: A literature search through Medline, EMBASE and Cochrane databases resulted in 22 pertinent manuscripts. Selected studies evaluated the locoregional role of SABR in gynaecological tumours, regardless of SABR clinical indication...
February 13, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28188682/stereotactic-ablative-body-radiotherapy-for-inoperable-primary-kidney-cancer-a-prospective-clinical-trial
#3
Shankar Siva, Daniel Pham, Tomas Kron, Mathias Bressel, Jacqueline Lam, Tan Teng Han, Brent Chesson, Mark Shaw, Sarat Chander, Suki Gill, Nicholas R Brook, Nathan Lawrentschuck, Declan G Murphy, Farshad Foroudi
OBJECTIVE: To assess the feasibility and safety of stereotactic ablative body radiotherapy (SABR) for RCC in patients unsuitable for surgery. Secondary objectives were to assess oncologic and functional outcomes. MATERIALS AND METHODS: This was a prospective interventional clinical trial with institutional ethics board approval. Inoperable patients were enrolled after multidisciplinary consensus for intervention and informed consent. Tumor response was defined using RECIST 1...
February 10, 2017: BJU International
https://www.readbyqxmd.com/read/28183024/high-field-hyperpolarization-exsy-experiment-for-fast-determination-of-dissociation-rates-in-sabre-complexes
#4
Niels K J Hermkens, Martin C Feiters, Floris P J T Rutjes, Sybren S Wijmenga, Marco Tessari
SABRE (Signal Amplification By Reversible Exchange) is a nuclear spin hyperpolarization technique based on the reversible concurrent binding of small molecules and para-hydrogen (p-H2) to an iridium metal complex in solution. At low magnetic field, spontaneous conversion of p-H2 spin order to enhanced longitudinal magnetization of the nuclear spins of the other ligands occurs. Subsequent complex dissociation results in hyperpolarized substrate molecules in solution. The lifetime of this complex plays a crucial role in attained SABRE NMR signal enhancements...
January 21, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28165752/mechanism-of-me-re-bond-addition-to-platinum-ii-and-dioxygen-activation-by-the-resulting-pt-re-bimetallic-center
#5
Kothanda Rama Pichaandi, Lara Kabalan, Hashem Amini, Guanghui Zhang, Hanyu Zhu, Hilkka I Kenttämaa, Phillip E Fanwick, Jeffrey T Miller, Sabre Kais, S Masoud Nabavizadeh, Mehdi Rashdi, Mahdi M Abu-Omar
Unusual cis-oxidative addition of methyltrioxorhenium (MTO) to [PtMe2(bpy)], (bpy = 2,2'-bipyridine) (1) is described. Addition of MTO to 1 first gives the Lewis acid-base adduct [(bpy)Me2Pt-Re(Me)(O)3] (2) and subsequently affords the oxidative addition product [(bpy)Me3PtReO3] (3). All complexes 1, MTO, 2, and 3 are in equilibrium in solution. The structure of 2 was confirmed by X-ray crystallography, and its dissociation constant in solution is 0.87 M. The structure of 3 was confirmed by extended X-ray absorption fine structure and X-ray absorption near-edge structure in tandem with one- and two-dimensional NMR spectroscopy augmented by deuterium and (13)C isotope-labeling studies...
February 6, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28164800/measurement-equivalence-a-non-technical-primer-on-categorical-multi-group-confirmatory-factor-analysis-in-school-psychology
#6
Laura L Pendergast, Nathaniel von der Embse, Stephen P Kilgus, Katie R Eklund
Evidence-based interventions (EBIs) have become a central component of school psychology research and practice, but EBIs are dependent upon the availability and use of evidence-based assessments (EBAs) with diverse student populations. Multi-group confirmatory factor analysis (MG-CFA) is an analytical tool that can be used to examine the validity and measurement equivalence/invariance of scores across diverse groups. The objective of this article is to provide a conceptual and procedural overview of categorical MG-CFA, as well as an illustrated example based on data from the Social and Academic Behavior Risk Screener (SABRS) - a tool designed for use in school-based interventions...
February 2017: Journal of School Psychology
https://www.readbyqxmd.com/read/28164465/solar-cells-materials-by-design-hybrid-pyroxene-corner-sharing-vo4-tetrahedral-chains
#7
Fedwa El-Mellouhi, Akinlolu Akande, Carlo Motta, Sergey Rashkeev, Golibjon Berdiyorov, Mohamed El-Amine El Amine Madjet, Asma Marzouk, El Tayeb Bentria, Stefano Sanvito, Sabre Kais, Fahhad Hussain Al Harbi
Hybrid organic-inorganic frameworks provide numerous combinations of materials with a wide range of structural and electronic properties, which enable their use in various applications. In recent years, some of these hybrid materials (especially lead-based halide perovskites) have been successfully used for the development of highly ecient solar cells. The large variety of possible hybrid materials inspired us into the search of other organic-inorganic frameworks, which may exhibit enhanced performance when compared to conventional lead-halide perovskites...
February 5, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28149896/is-it-time-for-sabr-to-overtake-surgery-as-the-treatment-of-choice-for-stage-i-non-small-cell-lung-cancer
#8
COMMENT
Susannah M Love, Gillian Hardman, Ruchir Mashar, Rajesh D Shah
No abstract text is available yet for this article.
December 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28148511/injuries-in-elite-korean-fencers-an-epidemiological-study
#9
Ki Jun Park, Song Brian Byung
PURPOSE: We aimed to assess the risk of injury associated with training activities in a population of elite Korean fencers training for the Olympic games. METHODS: We analysed the incidence of sports injuries, based on data prospectively collected over an 8-year period (January 2008 to December 2015) at the National Training Center in Seoul, Korea. The population of elite fencing athletes was stratified according to fencing category (sabre, epee and foil), sex, injury location (body region and site) and injury severity (mild or level I injury, requiring treatment for 1-3 days; moderate or level II injury, requiring treatment for 4-7 days; and severe or level III injury, requiring treatment for ≥8 days)...
February 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28142293/a-case-report-of-coup-de-sabre-patient-with-hair-transplantation
#10
Yeqin Dai, Ai-E Xu, Junhua He
BACKGROUND: Treatment of coup de sabre must remain conservative until the disease is no longer in an active state. When activity has ceased, some operative intervention is safe and effective for the correction of deformity. While hair transplantation showed high survival rates for the correction of cicatricial alopecia, it has rarely reported to be performed for the correction of coup de sabre. OBJECTIVE: To assess the therapeutic possibility of hair transplantation for the correction of coup de sabre...
January 31, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28129789/short-report-interim-safety-results-for-a-phase-ii-trial-measuring-the-integration-of-stereotactic-ablative-radiotherapy-sabr-plus-surgery-for-early-stage-non-small-cell-lung-cancer-missile-nsclc
#11
David A Palma, Timothy K Nguyen, Keith Kwan, Stewart Gaede, Mark Landis, Richard Malthaner, Dalilah Fortin, Alexander V Louie, Eric Frechette, George B Rodrigues, Brian Yaremko, Edward Yu, A Rashid Dar, Ting-Yim Lee, Al Gratton, Andrew Warner, Aaron Ward, Richard Inculet
: A phase II trial was launched to evaluate if neoadjuvant stereotactic ablative radiotherapy (SABR) before surgery improves oncologic outcomes in patients with stage I non-small cell lung cancer (NSCLC). We report a mandated interim safety analysis for the first 10 patients who completed protocol treatment. Operable patients with biopsy-proven T1-2 N0 NSCLC were eligible. SABR was delivered using a risk-adapted fractionation (54Gy/3 fractions, 55/5 or 60/8). Surgical resection was planned 10 weeks later at a high-volume center (>200 lung cancer resections annually)...
January 27, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28126325/stereotactic-ablative-radiation-therapy-for-lung-oligometastases-predictive-parameters-of-early-response-by-18-fdg-pet-ct
#12
Rosario Mazzola, Alba Fiorentino, Gioacchino Di Paola, Niccolò Giaj Levra, Francesco Ricchetti, Sergio Fersino, Umberto Tebano, Stefano Pasetto, Ruggero Ruggieri, Matteo Salgarello, Filippo Alongi
OBJECTIVES: The objective of this study was to investigate fludeoxyglucose F 18 positron emission tomography/computed tomography ((18)FDG-PET/CT) parameters as predictive of response after stereotactic ablative radiotherapy (SABR) for lung oligometastases. METHODS: The inclusion criteria of the current retrospective study were as follows: (1) lung oligometastases treated by SABR, (2) presence of (18)FDG-PET/CT before and after SABR for at least two subsequent evaluations, (3) Karnofsky performance status higher than 80, and (4) life expectancy longer than 6 months...
January 24, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28122893/clinical-outcomes-of-stereotactic-ablative-radiotherapy-in-patients-with-pulmonary-metastasis
#13
Bum-Sup Jang, Hak Jae Kim, Byoung Hyuck Kim, Dong-Wan Kim, Young Tae Kim, Young Whan Kim, Myoung-Jin Jang, Hong-Gyun Wu
BACKGROUNDS: In addition to its curative use for early stage lung cancer, stereotactic ablative radiotherapy is also indicated for pulmonary metastatic disease. Aims of this study were to retrospectively analyze treatment outcomes and to find prognostic factors for survivals. METHODS: Treatment outcomes and toxicities of 85 cases of SABR in 72 patients were retrospectively reviewed from September 2012 to April 2015. Prognostic factors were analyzed using Cox proportional hazards regression...
January 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28117079/a-national-dosimetry-audit-for-stereotactic-ablative-radiotherapy-in-lung
#14
Gail Distefano, Jonny Lee, Shakardokht Jafari, Clare Gouldstone, Colin Baker, Helen Mayles, Catharine H Clark
BACKGROUND AND PURPOSE: A UK national dosimetry audit was carried out to assess the accuracy of Stereotactic Ablative Body Radiotherapy (SABR) lung treatment delivery. METHODS AND MATERIALS: This mail-based audit used an anthropomorphic thorax phantom containing nine alanine pellets positioned in the lung region for dosimetry, as well as EBT3 film in the axial plane for isodose comparison. Centres used their local planning protocol/technique, creating 27 SABR plans...
January 20, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28116853/utility-of-68-ga-prostate-specific-membrane-antigen-positron-emission-tomography-in-diagnosis-and-response-assessment-of-recurrent-renal-cell-carcinoma
#15
Shankar Siva, Jason Callahan, David Pryor, Jarad Martin, Nathan Lawrentschuk, Michael S Hofman
INTRODUCTION: Prostate specific membrane antigen (PSMA) positron emission tomography (PET) is an emerging imaging modality in prostate cancer. However, (68) Ga-PSMA-PET may also have diagnostic utility in the setting of renal cell carcinoma (RCC). We investigate the differential role of (18) F-fluorodeoxyglucose (FDG) and PSMA-PET/CT scanning in patients with oligometastatic RCC. In particular, we focus on the utility of PSMA-PET for diagnostic evaluation of isolated or limited metastases planned for local surgery or radiation, as well as the potential utility of PSMA-PET for therapeutic response assessment in patients receiving stereotactic ablative body radiotherapy (SABR)...
January 24, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28095769/pcm-sabre-a-platform-for-benchmarking-and-comparing-outcome-prediction-methods-in-precision-cancer-medicine
#16
Noah Eyal-Altman, Mark Last, Eitan Rubin
BACKGROUND: Numerous publications attempt to predict cancer survival outcome from gene expression data using machine-learning methods. A direct comparison of these works is challenging for the following reasons: (1) inconsistent measures used to evaluate the performance of different models, and (2) incomplete specification of critical stages in the process of knowledge discovery. There is a need for a platform that would allow researchers to replicate previous works and to test the impact of changes in the knowledge discovery process on the accuracy of the induced models...
January 17, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28093143/re-predictive-parameters-of-symptomatic-hematochezia-following-5-fraction-gantry-based-sabr-in-prostate-cancer
#17
Samir S Taneja
No abstract text is available yet for this article.
February 2017: Journal of Urology
https://www.readbyqxmd.com/read/28073251/interfaces-select-specific-stereochemical-conformations-the-isomerization-of-glyoxal-at-the-liquid-water-interface
#18
Chongqin Zhu, Sabre Kais, Xiao Cheng Zeng, Joseph S Francisco, Ivan Gladich
Interfacial chemistry involving glyoxal at aerosol surfaces is postulated to catalyze aerosol growth. This chemistry remains speculative due to a lack of detailed information concerning the physicochemical behavior of glyoxal at the interface of atmospheric aerosols. Here, we report results from high-level electronic structure calculations as well as both classical and Born-Oppenheimer ab initio molecular dynamics simulations of glyoxal solvation at the air/liquid water interface. When compared to the gas phase, the trans to cis isomerization of glyoxal at the liquid water interface is found to be catalyzed; additionally, the trans conformation is selectively solvated within the bulk to a greater degree than is the cis conformation...
January 11, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28058710/stereotactic-ablative-radiotherapy-for-patients-with-unresectable-or-medically-inoperable-cholangiocarcinoma
#19
Ming-Yueh Liu, Cheng-Hsiang Lo, Chun-Shu Lin, Hsing-Lung Chao, Jen-Fu Yang, Kuen-Tze Lin, Chao-Yueh Fan, Yu-Fu Su, Wen-Yen Huang
PURPOSE: The role of stereotactic ablative radiotherapy (SABR) in patients with unresectable or medically inoperable cholangiocarcinoma remains unclear. We examined the efficacy and safety of SABR in this group of patients. METHODS: From January 2008 to December 2014, 15 patients with 17 lesions were included in this study. The lesions included 14 intrahepatic, 1 hilar, and 2 distal bile duct tumors. Three patients were classified as medically inoperable because of old age or multiple comorbidities...
January 5, 2017: Tumori
https://www.readbyqxmd.com/read/28055252/the-role-of-technology-in-clinical-trials-using-stereotactic-body-radiotherapy
#20
Marianne Camille Aznar, Alejandra Méndez Romero, Ben Jm Heijmen
Stereotactic body radiotherapy is a highly technology-driven treatment modality. The wider availability of in-room imaging and advanced radiotherapy delivery techniques has led to more and more institutions offering SABR. While some technological challenges remain, the crucial point for the next generation of SABR clinical trials is that today's technology is used correctly and close to its optimal potential for accuracy. The credentialing procedure of SABR needs to be extensive, but this investment will benefit the trial itself, the patients, and the professionals involved...
January 5, 2017: British Journal of Radiology
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