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Simeon Grazio, Branimir Anić
After the withdrawall of rofecoxib from worldwide market, there is ongoing debate whether gastrointestinal safety of COX-2 inhibition compared to non-selective NSAID-s may come at the cost of increased cardiovascular events. In this paper the relevant data regarding mechanisms, effects and side effects of selected COX-2 inhibitors are presented. Possible class effect is disscused and proposed alternative therapies.
2005: Reumatizam
P Miciński, A Wackermann-Ramos, M Manowska, P Buchacz, R Poreba, I Sirko
Acantosis Nigricans (AN) is a skin disease with rough or velvet areas present on neck or as hyperpigmented and wrinkled skin. AN often forms HAIR-AN syndrome consisted of hyperandrogenizm, insulin resistance and AN. We present AN and PCO syndrome in 13 yrs old girl treated by laparoscopic wedge resection. We concluded that laparoscopic procedure is a diagnostic measure and mode of PCO treatment. Decreased hyperandrogenizm resulted in AN appearance withdrawall.
May 1999: Ginekologia Polska
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