Obiageli Nnodu, Hezekiah Isa, Maxwell Nwegbu, Chinatu Ohiaeri, Samuel Adegoke, Reuben Chianumba, Ngozi Ugwu, Biobele Brown, John Olaniyi, Emmanuel Okocha, Juliet Lawson, Abdul-Aziz Hassan, Ijeoma Diaku-Akinwumi, Anazoeze Madu, Osita Ezenwosu, Yohanna Tanko, Umar Kangiwa, Ahmed Girei, Yetunde Israel-Aina, Adama Ladu, Perpetua Egbuzu, Usman Abjah, Angela Okolo, Nagihan Akbulut-Jeradi, Maria Fernandez, Frédéric B Piel, Adekunle Adekile
BACKGROUND: Sickle cell disease (SCD) is a neglected burden of growing importance. >312,000 births are affected annually by sickle cell anaemia (SCA). Early interventions such as newborn screening, penicillin prophylaxis and hydroxyurea can substantially reduce the mortality and morbidity associated with SCD. Nevertheless, their implementation in African countries has been mostly limited to pilot projects. Recent development of low-cost point-of-care testing (POCT) devices for sickle haemoglobin (HbS) could greatly facilitate the diagnosis of those affected...
September 2019: Blood Cells, Molecules & Diseases