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hypertensive disorder of pregnancy

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https://www.readbyqxmd.com/read/28742216/the-fetuses-at-risk-approach-survival-analysis-from-a-fetal-perspective
#1
K S Joseph, Michael S Kramer
Several phenomena in contemporary perinatology create challenges for analyzing pregnancy outcomes. These include recent increases in iatrogenic delivery at late preterm and early term gestation which are incongruent with the belief that stillbirth and neonatal death risk decrease exponentially with advancing gestational age. Perinatal epidemiologists have also puzzled over the paradox of intersecting birth weight- and gestational age-specific perinatal mortality curves for decades. For example, neonatal mortality rates among preterm infants of women who smoke are substantially lower than neonatal mortality rates among preterm infants of non-smoking women, whereas the reverse pattern occurs at term gestation...
July 25, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28733057/clinical-validation-of-non-invasive-cardiac-output-monitoring-in-healthy-pregnant-women
#2
Kelsey McLaughlin, Stephen P Wright, John C P Kingdom, John D Parker
OBJECTIVE: Non-invasive hemodynamic monitoring has the potential to be a valuable clinical tool for the screening and management of hypertensive disorders of pregnancy. The objective of this study was to validate the clinical utility of the non-invasive cardiac output monitoring (NICOM) system in pregnant women. METHODS: Twenty healthy pregnant women with a singleton pregnancy at 22 to 26 weeks' gestation were enrolled in this study. Measures of heart rate, stroke volume, and cardiac output were obtained through NICOM and compared with Doppler echocardiography...
July 18, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28731036/stroke-in-women-from-evidence-to-inequalities
#3
REVIEW
Charlotte Cordonnier, Nikola Sprigg, Else Charlotte Sandset, Aleksandra Pavlovic, Katharina S Sunnerhagen, Valeria Caso, Hanne Christensen
Stroke is the second largest cause of disability-adjusted life-years lost worldwide. The prevalence of stroke in women is predicted to rise rapidly, owing to the increasing average age of the global female population. Vascular risk factors differ between women and men in terms of prevalence, and evidence increasingly supports the clinical importance of sex differences in stroke. The influence of some risk factors for stroke - including diabetes mellitus and atrial fibrillation - are stronger in women, and hypertensive disorders of pregnancy also affect the risk of stroke decades after pregnancy...
July 21, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28729012/evidence-that-children-born-at-early-term-37-38-6-7-weeks-are-at-increased-risk-for-diabetes-and-obesity-related-disorders
#4
Dorit Paz Levy, Eyal Sheiner, Tamar Wainstock, Ruslan Sergienko, Daniella Landau, Asnat Walfisch
BACKGROUND: Prematurity is known to be associated with high rates of endocrine and metabolic complications in the offspring. Early term (37 0/7-38 6/7 weeks' gestation) born offspring were also shown to exhibit long term morbidity resembling that of late preterm, in several health categories. OBJECTIVE: We aimed to determine whether early term delivery impacts on the long-term endocrine and metabolic health of the offspring. STUDY DESIGN: A population-based cohort analysis was performed, including all term singleton deliveries occurring during 1991-2013 at a single regional tertiary medical center...
July 17, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28723784/thrombocytopenia-in-pregnancy-with-different-diagnoses-differential-clinical-features-treatments-and-outcomes
#5
Xiaoyue Wang, Yan Xu, Wenxiang Luo, Hui Feng, Yizhou Luo, Yanli Wang, Hui Liao
To investigate the clinical features and perinatal treatment of thrombocytopenia induced by different causes during pregnancy.Clinical data from 195 pregnant women with thrombocytopenia attending 2 tertiary hospitals from January 2014 to October 2016 were retrospectively studied. The obtained data were analyzed with SPSS 19.0 software.There were 117 (60.0%), 55 (28.2%), and 23 cases (11.8%) of pregnancy-associated thrombocytopenia (PAT), idiopathic thrombocytopenia (ITP), and hypertensive disorder in pregnancy (PIH), respectively...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28715959/preeclampsia-and-maternal-risk-of-breast-cancer-a-meta-analysis-of-cohort-studies
#6
Meizhen Sun, Yongling Fan, Yuanyuan Hou, Yanyan Fan
BACKGROUND: Pregnancy-related hypertensive disorders, including preeclampsia (PE) and pregnancy-induced hypertension (PIH), may influence the maternal risk of breast cancer. However, results of the cohort studies were inconsistent. METHODS: An updated meta-analysis of cohort studies was performed to evaluate the association between PE, PIH and maternal breast cancer incidence. Relevant studies were identified via searching of PubMed and Embase databases. A random effect model was applied to synthesize the results...
July 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28714660/maternal-mortality-in-the-developed-world-a-review-of-surveillance-methods-levels-and-causes-of-maternal-deaths-during-2006-2010
#7
Andreea A Creanga
This article provides an overview of surveillance methods, levels, and causes of maternal mortality in developed countries (Europe and the United States) during 2006-2010. Accurate identification of maternal deaths is not always possible, and no two countries in the world use the same surveillance methods for maternal mortality. Despite limitations (underestimation, missclassification), routine vital registration systems are the backbone of maternal mortality surveillance systems in developed countries. Enhanced surveillance methods involve linkages between deaths of women of reproductive age and births within the preceding year, or the use of additional data sources for maternal deaths...
July 17, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28712189/maternal-mortality-in-pakistan-is-there-any-metamorphosis-towards-betterment
#8
Nusrat Nisar, Razia Mustafa Abbasi, Shehla Raza Chana, Noushaba Rizwan, Razia Badar
BACKGROUND: Every year more than half million mother die due to pregnancy related preventable causes like haemorrhage, hypertensive disorders, sepsis, and obstructed labour and unsafe abortion. Among these deaths 99% occur in developing countries. The study was conducted to assess the maternal death rate and to analyse its trends over a period of 20 years in tertiary care hospital in Sindh Province Pakistan. METHODS: A retrospective analysis of maternal mortality records were carried out for a period of 20 years from 1986-1995 and 2011-2015 at the Department of Obstetrics and gynaecology Liaquat University of Medical and Health Sciences Hyderabad Sindh Pakistan...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28709727/consensus-bundle-on-severe-hypertension-during-pregnancy-and-the-postpartum-period
#9
Peter S Bernstein, James N Martin, John R Barton, Laurence E Shields, Maurice L Druzin, Barbara M Scavone, Jennifer Frost, Christine H Morton, Catherine Ruhl, Joan Slager, Eleni Z Tsigas, Sara Jaffer, M Kathryn Menard
Complications arising from hypertensive disorders of pregnancy are among the leading causes of preventable severe maternal morbidity and mortality. Timely and appropriate treatment has the potential to significantly reduce hypertension-related complications. To assist health care providers in achieving this goal, this patient safety bundle provides guidance to coordinate and standardize the care provided to women with severe hypertension during pregnancy and the postpartum period. This is one of several patient safety bundles developed by multidisciplinary work groups of the National Partnership for Maternal Safety under the guidance of the Council on Patient Safety in Women's Health Care...
July 1, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28708899/the-cost-effectiveness-of-a-quality-improvement-program-to-reduce-maternal-and-fetal-mortality-in-a-regional-referral-hospital-in-accra-ghana
#10
David M Goodman, Rohit Ramaswamy, Marc Jeuland, Emmanuel K Srofenyoh, Cyril M Engmann, Adeyemi J Olufolabi, Medge D Owen
OBJECTIVE: To evaluate the cost-effectiveness of a quality improvement intervention aimed at reducing maternal and fetal mortality in Accra, Ghana. DESIGN: Quasi-experimental, time-sequence intervention, retrospective cost-effectiveness analysis. METHODS: Data were collected on the cost and outcomes of a 5-year Kybele-Ghana Health Service Quality Improvement (QI) intervention conducted at Ridge Regional Hospital, a tertiary referral center in Accra, Ghana, focused on systems, personnel, and communication...
2017: PloS One
https://www.readbyqxmd.com/read/28708575/is-forty-the-new-thirty-population-based-study-of-advanced-maternal-age
#11
Gabrijela Brzan Simenc, Isaac Blickstein, Ivan Verdenik, Andreja Trojner Bregar, Miha Lucovnik, Natasa Tul
OBJECTIVE: To compare perinatal outcomes in different advanced maternal age groups. PATIENTS AND METHODS: We used a population-based data set to compare perinatal outcomes in three maternal age groups: 30-34.9, 35-39.9, and in women over 40 years. RESULTS: Over a 10-year period there were 23,422 (25.2%) births in the 35-39.9 years group, 3987 (4.3%) in the over 40 years group, and 65,492 births (70.5%) in our reference group (30-34.9 years)...
July 14, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28705906/hypertensive-disorders-of-pregnancy
#12
EDITORIAL
Helen L Barrett, Leonie K Callaway
No abstract text is available yet for this article.
July 13, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28705740/proteomics-analysis-of-human-placenta-reveals-glutathione-metabolism-dysfunction-as-the-underlying-pathogenesis-for-preeclampsia
#13
Xiaohan Jin, Zhongwei Xu, Jin Cao, Ping Shao, Maobin Zhou, Zhe Qin, Yan Liu, Fang Yu, Xin Zhou, Wenjie Ji, Wei Cai, Yongqiang Ma, Chengyan Wang, Nana Shan, Ning Yang, Xu Chen, Yuming Li
Hypertensive disorder in pregnancy (HDP) refers to a series of diseases that cause the hypertension during pregnancy, including HDP, preeclampsia (PE) and eclampsia. This study screens differentially expressed proteins of placenta tissues in PE cases using 2D LC-MS/MS quantitative proteomics strategy. A total of 2281 proteins are quantified, of these, 145 altering expression proteins are successfully screened between PE and control cases (p<0.05). Bioinformatics analysis suggests that these proteins are mainly involved in many biological processes, such as oxidation reduction, mitochondrion organization, and acute inflammatory response...
July 10, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28701338/lifestyle-in-progression-from-hypertensive-disorders-of-pregnancy-to-chronic-hypertension-in-nurses-health-study-ii-observational-cohort-study
#14
Simon Timpka, Jennifer J Stuart, Lauren J Tanz, Eric B Rimm, Paul W Franks, Janet W Rich-Edwards
Objectives To study the association between lifestyle risk factors and chronic hypertension by history of hypertensive disorders of pregnancy (HDP: gestational hypertension and pre-eclampsia) and investigate the extent to which these risk factors modify the association between HDP and chronic hypertension.Design Prospective cohort study.Setting Nurses' Health Study II (1991-2013).Participants 54 588 parous women aged 32 to 59 years with data on reproductive history and without previous chronic hypertension, stroke, or myocardial infarction...
July 12, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28701333/risk-of-post-pregnancy-hypertension-in-women-with-a-history-of-hypertensive-disorders-of-pregnancy-nationwide-cohort-study
#15
Ida Behrens, Saima Basit, Mads Melbye, Jacob A Lykke, Jan Wohlfahrt, Henning Bundgaard, Baskaran Thilaganathan, Heather A Boyd
Objectives To determine how soon after delivery the risk of post-pregnancy hypertension increases in women with hypertensive disorders of pregnancy and how the risk evolves over time.Design Nationwide register based cohort study.Setting Denmark.Populations 482 972 primiparous women with a first live birth or stillbirth between 1995 and 2012 (cumulative incidence analyses), and 1 025 118 women with at least one live birth or stillbirth between 1978 and 2012 (Cox regression analyses).Main outcome measures 10 year cumulative incidences of post-pregnancy hypertension requiring treatment with prescription drugs, and hazard ratios estimated using Cox regression...
July 12, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28701078/effects-of-context-aware-patient-guidance-on-blood-pressure-self-measurement-adherence-levels
#16
Camilla Lindahl, Stefan Wagner, Niels Uldbjerg, Jacob Mørup Schlütter, Olav Bertelsen, Puk Sandager
Hypertensive disease and preeclampsia are serious medical disorders affecting pregnancy. Screening in early pregnancy may identify women at risk of developing hypertensive disease and enable prophylactic treatment. Accurate blood pressure measurement is an important part of this screening. The aim of this study was to investigate whether patients, with the aid of a context-aware sensor-based blood pressure self-measurement system, were able to correctly self-measure their blood pressure adhering to internationally established recommendations...
July 1, 2017: Health Informatics Journal
https://www.readbyqxmd.com/read/28697657/anemia-and-pregnancy-outcomes-a-longitudinal-study
#17
K Tunkyi, J Moodley
OBJECTIVES: To determine the prevalence of anemia at the first antenatal visit and at 32-34 weeks gestational age, and to evaluate perinatal and maternal outcomes. METHODS: Venous blood samples were obtained for complete blood counts at both study visits. Maternal and perinatal morbidity and mortality were also recorded. The data were analyzed using SPSS (version 23). RESULTS: Two thousand pregnant women were recruited. The prevalence of anemia was 42...
July 11, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28697534/consensus-bundle-on-severe-hypertension-during-pregnancy-and-the-postpartum-period
#18
Peter S Bernstein, James N Martin, John R Barton, Laurence E Shields, Maurice L Druzin, Barbara M Scavone, Jennifer Frost, Christine H Morton, Catherine Ruhl, Joan Slager, Eleni Z Tsigas, Sara Jaffer, M Kathryn Menard
Complications arising from hypertensive disorders of pregnancy are among the leading causes of preventable severe maternal morbidity and mortality. Timely and appropriate treatment has the potential to significantly reduce hypertension-related complications. To assist health care providers in achieving this goal, this patient safety bundle provides guidance to coordinate and standardize the care provided to women with severe hypertension during pregnancy and the postpartum period. This is one of several patient safety bundles developed by multidisciplinary work groups of the National Partnership for Maternal Safety under the guidance of the Council on Patient Safety in Women's Health Care...
July 11, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28697109/pregnancy-related-mortality-in-the-united-states-2011-2013
#19
Andreea A Creanga, Carla Syverson, Kristi Seed, William M Callaghan
OBJECTIVE: To update national population-level pregnancy-related mortality estimates and examine characteristics and causes of pregnancy-related deaths in the United States during 2011-2013. METHODS: We conducted an observational study using population-based data from the Pregnancy Mortality Surveillance System to calculate pregnancy-related mortality ratios by year, age group, and race-ethnicity groups. We explored 10 cause-of-death categories by pregnancy outcome during 2011-2013 and compared their distribution with those in our earlier reports since 1987...
July 7, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28697093/national-partnership-for-maternal-safety-consensus-bundle-on-severe-hypertension-during-pregnancy-and-the-postpartum-period
#20
Peter S Bernstein, James N Martin, John R Barton, Laurence E Shields, Maurice L Druzin, Barbara M Scavone, Jennifer Frost, Christine H Morton, Catherine Ruhl, Joan Slager, Eleni Z Tsigas, Sara Jaffer, M Kathryn Menard
Complications arising from hypertensive disorders of pregnancy are among the leading causes of preventable severe maternal morbidity and mortality. Timely and appropriate treatment has the potential to significantly reduce hypertension-related complications. To assist health care providers in achieving this goal, this patient safety bundle provides guidance to coordinate and standardize the care provided to women with severe hypertension during pregnancy and the postpartum period. This is one of several patient safety bundles developed by multidisciplinary work groups of the National Partnership for Maternal Safety under the guidance of the Council on Patient Safety in Women's Health Care...
July 7, 2017: Obstetrics and Gynecology
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