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Cervical cancer epidemiology

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https://www.readbyqxmd.com/read/28520854/declines-in-hpv-associated-high-grade-cervical-lesions-after-introduction-of-hpv-vaccines-in-connecticut-us-2008-2015
#1
Linda M Niccolai, James I Meek, Monica Brackney, James L Hadler, Lynn E Sosa, Daniel M Weinberger
Background: Trends in HPV-associated cervical lesions can provide an indication of vaccine impact. Our purpose was to measure trends in cervical lesions during 2008-2015 and to consider possible explanations including vaccination coverage, changes in screening for cervical cancer, and risk behaviors for acquiring HPV. Methods: Connecticut (CT) implemented mandatory reporting of cervical intraepithelial neoplasia grades 2/3 and adenocarcinoma in situ (CIN2+) in 2008...
May 17, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28511636/hpv-prevalence-and-type-distribution-in-cypriot-women-with-cervical-cytological-abnormalities
#2
George Krashias, Dana Koptides, Christina Christodoulou
BACKGROUND: Human papillomavirus (HPV) is the most common sexually transmitted agent, and it can cause cervical lesions and cancer in females. Currently, information regarding the prevalence of HPV in Cyprus is lacking. The aim of this study was to evaluate the HPV type-specific prevalence in 596 women, aged 19-65 years, with cytological abnormalities. Additionally, in a subset of 348 women for whom cytology results of the Pap test were available, the association between HPV infection and cervical disease was investigated...
May 16, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28499530/recognition-and-therapeutic-options-for-malignancy-of-the-cervix-and%C3%A2-uterus
#3
REVIEW
Elizabeth R Burton, Joel I Sorosky
An update on the current epidemiology and a review of the risk factors of cervical and endometrial cancers are discussed. Cervical cancer prevention with a focus on human papillomavirus vaccination and cervical cancer screening is reviewed, emphasizing the new focus of less frequent intervention in an effort to maintain high rates of early detection of disease while decreasing unnecessary and anxiety-provoking colposcopies, biopsies, and excisional procedures. The replacement of traditional endometrial hyperplasia terminology with more relevant clinical categories, with an emphasis on the introduction of endometrial intraepithelial neoplasia, is presented...
June 2017: Obstetrics and Gynecology Clinics of North America
https://www.readbyqxmd.com/read/28440679/cervical-cancer-in-sub-saharan-africa-a-preventable-noncommunicable-disease
#4
Ralph-Sydney Mboumba Bouassa, Thierry Prazuck, Thérèse Lethu, Mohammad-Ali Jenabian, Jean-François Meye, Laurent Bélec
Infections caused by high-risk human papillomavirus (HPV) are responsible for 7.7% of cancers in developing countries, mainly cervical cancer. This disease is steadily increasing in sub-Saharan Africa, with more than 75,000 new cases and 50,000 deaths yearly, further increased by HIV infection. Areas covered: The current status of cervical cancer associated with HPV in sub-Saharan Africa has been systematically revised. The main issues discussed here are related to the public health burden of cervical cancer in sub-Saharan Africa and predictions for the coming decades, including molecular epidemiology and determinants of HPV infection in Africa, and promising prevention measures currently being evaluated in Africa...
May 5, 2017: Expert Review of Anti-infective Therapy
https://www.readbyqxmd.com/read/28437708/primary-secondary-and-tertiary-prevention-of-human-papillomavirus-driven-head-and-neck-cancers
#5
REVIEW
Haïtham Mirghani, Alain C Jung, Carole Fakhry
Human papillomavirus (HPV)-driven oropharyngeal cancers (OPCs) represent an increasing proportion of head and neck cancers that could become, in the next few decades, a public health problem in certain western countries. This significant epidemiological change strongly calls for preventive measures. Prophylactic HPV vaccination and screening programmes for early identification and treatment of premalignant lesions are currently being used to reduce the incidence of uterine cervical cancer, which is the paradigm of HPV-driven malignancy...
April 19, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28431558/epidemiology-and-genotype-distribution-of-human-papillomavirus-hpv-in-southwest-china-a-cross-sectional-five-years-study-in-non-vaccinated-women
#6
Yishu Tang, Lan Zheng, Shuangshuang Yang, Bing Li, Huiting Su, Li-Ping Zhang
BACKGROUND: Large-size data on type-specific HPV prevalence in Southwest China are required to estimate the cervical cancer burden in the country and to prepare for HPV-based cervical screening program and further HPV vaccination of China. This HPV study is a pooled analysis of data from five years in Chongqing of China, which is cross-sectional in design using data collecting. RESULTS: The positivity of HPV was 26.2% (10542/40311), single type was 25.7% (10360/40311), multiple type was 8...
April 21, 2017: Virology Journal
https://www.readbyqxmd.com/read/28415705/meta-analysis-of-xrcc1-polymorphism-and-risk-of-female-reproductive-system-cancer
#7
Na-Na Yang, Ying-Fan Huang, Jian Sun, Ying Chen, Zhong-Min Tang, Jin-Fang Jiang
Numerous epidemiological studies have evaluated the association between polymorphism in the gene encoding x-ray repair cross complementing 1 (XRCC1) protein and the risk of female reproductive system cancer, but results are inconclusive. To gain a comprehensive picture of available evidence, we searched for relevant studies in the PubMed, EMBASE, Scopus, and Chinese National Knowledge Infrastructure databases up to December 17, 2016. A total of 26 case-control studies were picked out. The pooled odds ratio (OR) with its 95% confidence interval (CI) was calculated to estimate the association...
April 25, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415696/role-of-interleukin-12-gene-polymorphisms-in-the-onset-risk-of-cancer-a-meta-analysis
#8
Yi Zheng, Meng Wang, Tian Tian, Kang Liu, Xinghan Liu, Yajing Zhai, Shuai Lin, Pengtao Yang, Shanli Li, Zhijun Dai, Jun Lu
Many molecular epidemiologic studies have explored the possible links between interleukin-12 (IL-12) polymorphisms and various cancers. However, results from these studies remain inconsistent. This meta-analysis is aimed to shed light on the associations between three common loci (rs568408, rs2243115, rs3212227) of IL-12 gene and overall cancer risk. Our meta-analysis finally included 33 studies comprising 10,587 cancer cases and 12,040 cancer-free controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to assess the cancer risk...
May 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28403967/organization-and-first-results-of-cervical-cancer-screening-program-in-mayotte-from-2010-to-2014
#9
Z Stewart, E Garcin, A Nazac, C Mezan de Malartic, C Georges, A Cimmino
OBJECTIVES: Our main goal was to report the organization of individual screening for uterus cancer in Mayotte, the last French department since 2011, and its first results. MATERIAL AND METHODS: Epidemiological and observational study describing the prior situation, the beginning of the screening with pap smears in 2010, the colposcopy consultations and the treatment of the patients by the Mayotte network for screening of cancers since 2010. RESULTS: The screening allowed an improvement of the global cover rate from 5% to 24% in 5 years...
February 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28377417/cervical-infection-with-cutaneous-beta-and-mucosal-alpha-papillomaviruses
#10
Laura Sichero, Mariam El-Zein, Emily M Nunes, Silvaneide Ferreira, Eduardo L Franco, Luisa L Villa
BACKGROUND: Alpha-human papillomavirus (α-HPV) play a causal role in cervical cancer but little is known about the epidemiology of genital Beta-HPV infection. METHODS: We used Luminex and polymerase chain reaction (PCR) hybridization to detect β- and α-HPVs prevalence at enrolment and 12-months follow-up in cervical samples from 505 women enrolled in the Ludwig-McGill cohort study. We compared epidemiological correlates of both β- and α-HPVs and compared genotypes between these genera with respect to co-occurrence and association with cervical cytological abnormalities...
April 4, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28365936/new-software-for-collecting-data-from-the-organized-cervical-cancer-screening-program-in-serbia-are-we-on-the-threshold-of-a-new-screening-registry-a-multicentric-study
#11
Tamara Naumovic, Vesna Lakic, Ana Jovicevic, Dragan Ilic, Predrag Milosevic, Vesna Stevic-Gajic, Ana Antonijevic, Nada Milovanovic, Ivica Magdic, Rajko Koricanac, Sasa Malkov, Igor Grkavac, Milos Mihajlovic, Slavisa Djuricic, Branislava Zivkovic, Uros Stegic, Zorka Milovanovic, Dejan Opric, Marija Knezevic, Verica Jovanovic, Zoran Todorovic, Dusan Todorovic
PURPOSE: The purpose of this study was to present the Screening Registry and the results of organized cervical cancer screening program (OCCSP) in the Republic of Serbia using a database made as an output model, linked with the Screening Registry. METHODS: Data were respectively collected over a onemonth period from 3 state primary health care centers (and related hospitals/clinical center) in central Serbia in which OCCSP was conducted. The sample consisted of women of the target population (25 to 64 years old) who responded the call for Pap test...
January 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28340612/the-singular-epidemiology-of-hpv-infection-among-french-guianese-women-with-normal-cytology
#12
Antoine Adenis, Valentin Dufit, Maylis Douine, Fatiha Najioullah, Vincent Molinie, Dominique Catherine, Odile Kilié, Nadia Thomas, Jean Luc Deshayes, Paul Brousse, Hatem Ben Amor, Remy Pignoux, Gabriel Carles, Claire Grenier, Vincent Lacoste, Raymond Cesaire, Mathieu Nacher
BACKGROUND: In French Guiana, cervical cancer is the second most frequent cancer in females. The objective of the present study was to describe the prevalence of HPV infections in women with normal cervical cytology living in the remote villages of French Guiana. METHODS: Before the study, the study team communicated in the remote villages on the importance of screening. All women from the target population were offered to participate. They signed informed consent during inclusion and then had a concomitant HPV-test and cervical smear...
March 24, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28325903/whole-genome-analysis-of-human-papillomavirus-types-16-18-and-58-isolated-from-cervical-precancer-and-cancer-samples-in-chinese-women
#13
Ying Liu, Yaqi Pan, Weijiao Gao, Yang Ke, Zheming Lu
Human papillomavirus (HPV) types 16, 18 and 58 are ranked the top three high-risk HPV types for cervical intraepithelial neoplasia (CIN) and invasive carcinoma. We aimed to evaluate the diversity of HPV16, HPV18, and HPV58 genetic variants by HPV capture technology combined with next generation sequencing. 295, 73, and 148 variations were observed in 51 HPV16, 7 HPV18, and 11 HPV58 genomes, respectively. HPV16 isolates were predominantly of the A variant lineage, and sublineage A4 (Asian) was the most common...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28279589/difference-of-stage-at-cancer-diagnosis-by-socioeconomic-status-for-four-target-cancers-of-the-national-cancer-screening-program-in-korea-results-from-the-gwangju-and-jeonnam-cancer-registries
#14
Sun-Seog Kweon, Min-Gyeong Kim, Mi-Ran Kang, Min-Ho Shin, Jin-Su Choi
BACKGROUND: The aim of this study was to evaluate whether stage at cancer diagnosis differed according to patient economic status. METHODS: A total of 10,528 patients with cancer of the stomach, colorectum, breast, or cervix, which are target organs of the Korean National Cancer Screening Program (NCSP; fully implemented in 2005) were extracted from population-based cancer registries. The patients were classified into four groups based on socioeconomic status (SES), as determined using their National Health Insurance (NHI) monthly premium at the time of cancer diagnosis...
March 6, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28279258/cervical-cancer-screening-epidemiology-as-the-necessary-but-not-sufficient-basis-of-public-health-practice
#15
EDITORIAL
Mark Schiffman
No abstract text is available yet for this article.
May 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28271692/colorimetric-detection-of-23-human-papillomavirus-genotypes-by-loop-mediated-isothermal-amplification
#16
Junxiao Lin, Biao Ma, Jiehong Fang, Ye Wang, Haizhen He, Wei Lin, Wei Su, Mingzhou Zhang
BACKGROUND: Human papillomavirus (HPV) infection is linked to cervical cancer. With the technological development of molecular biology and epidemiology, detection and treatment of HPV has become an important mean to prevent cervical cancer. METHODS: A simple, rapid, and sensitive colorimetric loop-mediated isothermal amplification (LAMP) method was established herein to detect 23 HPV genotypes. The sequences of the primers for the LAMP reaction were located in the L1 gene of the HPV genome...
March 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28265177/-epidemiology-prevention-and-early-detection-of-cervical-cancer
#17
Nicolas Wentzensen
BACKGROUND: Persistent infections with human papillomaviruses are a necessary cause of cervical carcinomas. The development of HPV-based prevention tools, HPV vaccination and HPV testing, is leading to major changes in cervical cancer prevention programs worldwide. A decade after introduction of HPV vaccination in many countries reductions of HPV infections and cancer precursors have been observed in young women. The focus is now on the integration of new approaches for screening of increasingly vaccinated populations...
October 2016: Der Onkologe: Organ der Deutschen Krebsgesellschaft E.V
https://www.readbyqxmd.com/read/28245782/reactive-oxygen-and-nitrogen-species-in-carcinogenesis-implications-of-oxidative-stress-on-the-progression-and-development-of-several-cancer-types
#18
Joanna Kruk, Hassan Y Aboul-Enein
BACKGROUND: The body of evidence available from published literature during the past three decades indicates that reactive oxygen species and reactive nitrogen species can induce, promote and modulate carcinogenesis. OBJECTIVE: The purpose of this review was to present current status of knowledge on the possible role of oxidative/nitrosative stress in the development and progression of several human cancers. Moreover, we discuss briefly the formation and decomposition of oxygen and nitrogen species within cells and their physiological and damaging influences...
February 28, 2017: Mini Reviews in Medicinal Chemistry
https://www.readbyqxmd.com/read/28239004/cancer-mortality-in-the-mississippi-delta-region-descriptive-epidemiology-and-needed-future-research-and-interventions
#19
Whitney E Zahnd, Wiley D Jenkins, Georgia S Mueller-Luckey
The Delta Region is a federally designated, socioeconomically disadvantaged region of the United States covering 252 counties in eight states along the Mississippi River. The objective of this study is to describe the Region's cancer mortality burden. National Center for Health Statistics data were used to calculate age-adjusted mortality rates and rate ratios for the Delta Region for all cancers, lung, colorectal, breast (female), cervical, and prostate cancers. Rates were also calculated for comparison groups, and were stratified by gender, race, rurality, and socioeconomic status...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28225780/cancer-prevalence-incidence-and-mortality-in-people-who-experience-incarceration-in-ontario-canada-a-population-based-retrospective-cohort-study
#20
Fiona G Kouyoumdjian, Lucie Pivnick, Kathryn E McIsaac, Andrew S Wilton, Aisha Lofters, Stephen W Hwang
INTRODUCTION: Evidence suggests that many risk factors for cancer are overrepresented in people who experience incarceration, and data on cancer epidemiology are limited for this population. We aimed to describe cancer prevalence, incidence and mortality in adults admitted to provincial custody in Ontario, Canada in 2000. METHODS: We linked data on 48,166 adults admitted to provincial custody in Ontario in 2000 with Ontario Cancer Registry data to 2012. We calculated cancer prevalence in the 10 years prior to admission to custody in 2000, incidence between 2000 and 2012 and mortality between 2000 and 2011...
2017: PloS One
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