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adult cerebral palsy

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https://www.readbyqxmd.com/read/28427924/long-term-deterioration-of-perceived-health-and-functioning-in-adults-with-cerebral-palsy
#1
Joyce L Benner, Sander R Hilberink, Thessa Veenis, Henk J Stam, Wilma M A van der Slot, Marij E Roebroeck
OBJECTIVE: To describe longitudinal change in perceived health, presence of health issues and functional level in adults with cerebral palsy (CP). DESIGN: Prospective cohort study. SETTING: Participants who completed baseline assessments in 1996 or 2000 were invited for a long-term follow-up in 2010. PARTICIPANTS: Forty-nine Dutch adults with CP (age 35-45 years, 55% male, 75% spastic) formerly known in pediatric rehabilitation care...
April 17, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28422632/somatosensory-discrimination-intervention-improves-body-position-sense-and-motor-performance-in-children-with-hemiplegic-cerebral-palsy
#2
Belinda McLean, Susan Taylor, Eve Blair, Jane Valentine, Leeanne Carey, Catherine Elliott
OBJECTIVE: This study examined the use of the adult neuroscience-based Sense(©) intervention with children with hemiplegic cerebral palsy (HCP) to improve upper-limb somatosensory discrimination, motor function, and goal performance. METHOD: Seventeen children with HCP (9 boys, 8 girls; mean age = 10.2 yr) participated in this pilot matched-pairs trial with random allocation and 6-mo follow-up (intervention, n = 7; control, n = 10). The intervention group received Sense training 3×/wk for 6 wk (18 hr)...
May 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/28412577/describing-heterogeneity-of-unmet-needs-among-adults-with-a-developmental-disability-an-examination-of-the-2012-canadian-survey-on-disability
#3
Jennifer Zwicker, Arezou Zaresani, J C Herb Emery
BACKGROUND: As a signatory to the UN Convention on the Rights of Persons with Disabilities, Canada has committed to protect the rights and dignity of persons with developmental disabilities (DD), which means that labour markets, education, and training opportunities should be inclusive and accessible. PURPOSE: Describe the unmet employment, education and daily needs of adults with DD, with a sub analysis of persons with autism spectrum disorder (ASD) and cerebral palsy (CP) in Canada, to inform efficient and equitable policy development...
April 13, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28401027/beneficial-effects-of-childhood-selective-dorsal-rhizotomy-in-adulthood
#4
T S Park, Caleb Edwards, Jenny L Liu, Deanna M Walter, Matthew B Dobbs
 Selective dorsal rhizotomy (SDR) has been used to treat children with spastic cerebral palsy (CP) for over three decades. However, little is known about the outcomes of childhood SDR in adults.  Objectives: 1) To study the effects of childhood SDR on the quality of life and ambulatory function in adult life. 2) To determine late side effects of SDR in adults.   Methods: Adults (> 17.9 years) who underwent SDR in childhood (2 - 17.9 years) between 1987 and 2013 were surveyed in 2015. Patients completed a survey, including questions on demographic information, quality of life, health, surgical outcomes, motor function, manual ability, pain, braces/orthotics, post-SDR treatment, living situation, education level, work status, and side effects of SDR...
March 5, 2017: Curēus
https://www.readbyqxmd.com/read/28392287/blocked-delayed-or-obstructed-what-causes-poor-white-matter-development-in-intrauterine-growth-restricted-infants
#5
REVIEW
Mary Tolcos, Steven Petratos, Jonathan J Hirst, Flora Wong, Sarah J Spencer, Aminath Azhan, Ben Emery, David W Walker
Poor white matter development in intrauterine growth restricted (IUGR) babies remains a major, untreated problem in neonatology. New therapies, guided by an understanding of the mechanisms that underlie normal and abnormal oligodendrocyte development and myelin formation, are required. Much of our knowledge of the mechanisms that underlie impaired myelination come from studies in adult demyelinating disease, preterm brain injury, or experimental models of hypoxia-ischemia. However relatively less is known for IUGR which is surprising because IUGR is a leading cause of perinatal mortality and morbidity, second only to premature birth...
April 6, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/28389939/cross-sectional-study-of-urinary-problems-in-adults-with-cerebral-palsy-awareness-and-impact-on-the-quality-of-life
#6
Necmettin Yıldız, Yeşim Akkoç, Murat Ersöz, Berrin Gündüz, Belgin Erhan, Hilal Yesil, Ayşe Nur Bardak, Senay Ozdolap, Hakan Tunç, Kurtulus Koklu, Ebru Alemdaroğlu, Ender Erden, Ulas Sungur, Ozlem Satır, Cagdaş Erdogan, Hakan Alkan
We aimed to assess the functional status, urinary problems, and awareness of these problems in adults with cerebral palsy (CP) and their relationship with the quality of life. One-hundred-seventeen adults with CP (53 women, 64 men) were included in this study. Subjects were asked to fill out a urological questionnaire which dealt with urinary symptoms, awareness of urinary problems, and pharmacological treatment they received. Subjects were also assessed with the Gross Motor Function Classification System (GMFCS), Functional Independence Measures (FIM), Functional Mobility Scale (FMS), and King's Health Questionnaire (KHQ)...
April 7, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28350770/commentary-on-gait-training-with-visual-feedback-and-proprioceptive-input-to-reduce-gait-asymmetry-in-adults-with-cerebral-palsy-a-case-series
#7
Connie C Johnson, Mary Beth A Osborne
No abstract text is available yet for this article.
April 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28350769/gait-training-with-visual-feedback-and-proprioceptive-input-to-reduce-gait-asymmetry-in-adults-with-cerebral-palsy-a-case-series
#8
Ilana Levin, Michael D Lewek, Jeff Feasel, Deborah E Thorpe
PURPOSE: The purpose of this case series was to investigate the feasibility of using visual feedback on gait asymmetry during gait retraining and whether this leads to reduced asymmetry, improvement in gait speed, cost of walking, and dynamic balance in ambulant adults with cerebral palsy (CP). METHODS: Five adults with CP, who were ambulatory and had step length or stance time asymmetry, trained for 18 sessions on a split-belt treadmill with concurrent visual feedback from a virtual environment...
April 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28350415/anaerobic-exercise-testing-in-rehabilitation-a-systematic-review-of-available-tests-and-protocols
#9
Leonie A Krops, Trijntje Albada, Lucas H V van der Woude, Juha M Hijmans, Rienk Dekker
OBJECTIVE: Anaerobic capacity assessment in rehabilitation has received increasing scientific attention in recent years. However, anaerobic capacity is not tested consistently in clinical rehabilitation practice. This study reviews tests and protocols for anaerobic capacity in adults with various disabilities (spinal cord injury, cerebral palsy, cerebral vascular accident, lower-limb amputation(s)) and (able-bodied) wheelchair users. DATA SOURCES: PubMed, CINAHL and Web of Science...
March 28, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28304081/course-of-employment-in-adults-with-cerebral-palsy-over-a-14-year-period
#10
Joyce L Benner, Sander R Hilberink, Thessa Veenis, Wilma M A van der Slot, Marij E Roebroeck
AIM: To explore the course of employment in adults with cerebral palsy (CP) over 14 years, and to identify subgroups at risk for unemployment. METHOD: Sixty-five adults with CP (33 males, 32 females; baseline age 25y 8mo, standard deviation [SD] 3y 2mo; intellectual impairment 25%; bilateral CP 65%) participated in a prospective cohort study. Self-reports of employment and work hours per week in 1996, 2000, and 2010 were documented. The course of employment (including sheltered work) and work hours per week were analysed, using generalized estimating equations (GEE)...
March 17, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28288332/energy-cost-during-walking-in-association-with-age-and-body-height-in-children-and-young-adults-with-cerebral-palsy
#11
Eline A M Bolster, Astrid C J Balemans, Merel-Anne Brehm, Annemieke I Buizer, Annet J Dallmeijer
AIM: This cross-sectional study into children and young adults with cerebral palsy (CP) aimed to assess the association of gross energy cost (EC), net EC and net nondimensional (NN) EC during walking with age and body height, compared to typically developing (TD) peers. METHOD: Data was collected in 128 participants with CP (mean age 11y9mo; GMFCS I,n=48; II,n=56; III, n=24) and in 63 TD peers (mean age 12y5mo). Energy cost was assessed by measuring the oxygen consumption during over-ground walking at comfortable speed...
February 27, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28277557/inter-and-intra-rater-reliability-of-the-10-meter-walk-test-in-the-community-dweller-adults-with-spastic-cerebral-palsy
#12
Fariba Bahrami, Shohreh Noorizadeh Dehkordi, Mehdi Dadgoo
OBJECTIVE: We aimed to investigation the intra-rater and inter-raters reliability of the 10 meter walk test (10 MWT) in adults with spastic cerebral palsy (CP). MATERIALS & METHODS: Thirty ambulatory adults with spastic CP in the summer of 2014 participated (19 men, 11 women; mean age 28 ± 7 yr, range 18- 46 yr). Individuals were non-randomly selected by convenient sampling from the Ra'ad Rehabilitation Goodwill Complex in Tehran, Iran. They had GMFCS levels below IV (I, II, and III)...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/28275812/urinary-stone-disease-in-pediatric-and-adult-metabolic-bone-clinic-patients
#13
Andrew L Schwaderer, Abimbola Oduguwa, Kirsten Kusumi
Kidney stones are increasing in the pediatric and adult populations; similarly osteoporosis is increasingly recognized in children. While kidney stone formers are known to suffer from low bone density, metabolic bone patients have not been considered a high risk population for kidney stones. Retrospective chart review of Nationwide Children's Hospital Metabolic Bone Clinic patients from October 2009-2013. Patients were identified by ICD 9 codes for osteoporosis, osteopenia, low bone density and kidney stones...
March 8, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28269543/upper-limb-kinematics-of-adults-with-cerebral-palsy-on-bilateral-functional-tasks
#14
Carina Lott, Michelle J Johnson
Adults with cerebral palsy (CP) often show upper limb impairments which impact their ability to execute activities of daily living (ADLs). Three adults with CP and five healthy adults performed three types of bilateral and unilateral ADLs: drink, pour, and pick and place tasks. An affordable bilateral assessment system (BiAS) was used to measure wrist kinematic trajectories. Four metrics, total completion time, maximum velocity, smoothness, and phase difference, were used to evaluate each functional task. Overall, adults with CP took a longer time than the healthy subjects to complete all unilateral functional tasks with their non-dominant hand...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28265154/prevalence-of-secondary-impairments-of-adults-with-cerebral-palsy-according-to-gross-motor-function-classification-system
#15
Eun-Young Park, Won-Ho Kim
[Purpose] This study aimed to investigate the prevalence of secondary impairments in adults with cerebral palsy. [Subjects and Methods] The study sample included 52 adults with cerebral palsy who attended a convalescent or rehabilitation center for disabled individuals or a special school for physical disabilities in South Korea. [Results] The univariate analysis showed that the Gross Motor Functional Classification System level was a significant predictor of spondylopathies, general pain, arthropathies, and motor ability loss...
February 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28253550/olig1-is-required-for-noggin-induced-neonatal-myelin-repair
#16
Jennifer K Sabo, Vivi Heine, John C Silbereis, Lucas Schirmer, Steven W Levison, David H Rowitch
OBJECTIVE: Neonatal white matter injury (NWMI) is a lesion found in preterm infants that can lead to cerebral palsy. Although antagonists of bone morphogenetic protein (BMP) signaling, such as Noggin, promote oligodendrocyte precursor cell (OPC) production after hypoxic-ischemic (HI) injury, the downstream functional targets are poorly understood. The basic helix-loop-helix protein, oligodendrocyte transcription factor 1 (Olig1), promotes oligodendrocyte (OL) development and is essential during remyelination in adult mice...
April 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28243195/part-2-adaptation-of-gait-kinematics-in-unilateral-cerebral-palsy-demonstrates-preserved-independent-neural-control-of-each-limb
#17
Thomas C Bulea, Christopher J Stanley, Diane L Damiano
Motor adaptation, or alteration of neural control in response to a perturbation, is a potential mechanism to facilitate motor learning for rehabilitation. Central nervous system deficits are known to affect locomotor adaptation; yet we demonstrated that similar to adults following stroke, children with unilateral brain injuries can adapt step length in response to unilateral leg weighting. Here, we extend our analysis to explore kinematic strategies underlying step length adaptation and utilize dynamical systems approaches to elucidate how neural control may differ in those with hemiplegic CP across legs and compared to typically developing controls...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28229395/transcranial-magnetic-and-direct-current-stimulation-in-children
#18
REVIEW
Mustafa Q Hameed, Sameer C Dhamne, Roman Gersner, Harper L Kaye, Lindsay M Oberman, Alvaro Pascual-Leone, Alexander Rotenberg
Promising results in adult neurologic and psychiatric disorders are driving active research into transcranial brain stimulation techniques, particularly transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), in childhood and adolescent syndromes. TMS has realistic utility as an experimental tool tested in a range of pediatric neuropathologies such as perinatal stroke, depression, Tourette syndrome, and autism spectrum disorder (ASD). tDCS has also been tested as a treatment for a number of pediatric neurologic conditions, including ASD, attention-deficit/hyperactivity disorder, epilepsy, and cerebral palsy...
February 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28228720/motor-learning-abilities-are-similar-in-hemiplegic-cerebral-palsy-compared-to-controls-as-assessed-by-adaptation-to-unilateral-leg-weighting-during-gait-part-i
#19
Diane L Damiano, Christopher J Stanley, Thomas C Bulea, Hyung Soon Park
Introduction: Individuals with cerebral palsy (CP) demonstrate high response variability to motor training insufficiently accounted for by age or severity. We propose here that differences in the inherent ability to learn new motor tasks may explain some of this variability. Damage to motor pathways involving the cerebellum, which may be a direct or indirect effect of the brain injury for many with CP, has been shown to adversely affect the ability to learn new motor tasks and may be a potential explanation...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28227798/upper-limb-kinematics-of-adults-with-cerebral-palsy-on-bilateral-functional-tasks
#20
Carina Lott, Michelle J Johnson, Carina Lott, Michelle J Johnson, Carina Lott, Michelle J Johnson
Adults with cerebral palsy (CP) often show upper limb impairments which impact their ability to execute activities of daily living (ADLs). Three adults with CP and five healthy adults performed three types of bilateral and unilateral ADLs: drink, pour, and pick and place tasks. An affordable bilateral assessment system (BiAS) was used to measure wrist kinematic trajectories. Four metrics, total completion time, maximum velocity, smoothness, and phase difference, were used to evaluate each functional task. Overall, adults with CP took a longer time than the healthy subjects to complete all unilateral functional tasks with their non-dominant hand...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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