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https://www.readbyqxmd.com/read/28634326/a-chrysoporthe-cubensis-enzyme-cocktail-produced-from-a-low-cost-carbon-source-with-high-biomass-hydrolysis-efficiency
#1
Thiago Rodrigues Dutra, Valéria Monteze Guimarães, Ednilson Mascarenhas Varela, Lílian da Silva Fialho, Adriane Maria Ferreira Milagres, Daniel Luciano Falkoski, José Cola Zanuncio, Sebastião Tavares de Rezende
Low cost and high efficiency cellulolytic cocktails can consolidate lignocellulosic ethanol technologies. Sugarcane bagasse (SCB) is a low cost agro-industrial residue, and its use as a carbon source can reduce the costs of fungi cultivation for enzyme production. Chrysoporthe cubensis grown under solid state fermentation (SSF) with wheat bran has potential to produce efficient enzymatic extracts for SCB saccharification. This fungus was grown under submersed fermentation (SmF) and SSF with in natura SCB, pretreated with acid or alkali and with others carbon sources...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28628868/an-overview-on-exploration-and-environmental-impact-of-unconventional-gas-sources-and-treatment-options-for-produced-water
#2
REVIEW
Tânia L S Silva, Sergio Morales-Torres, Sérgio Castro-Silva, José L Figueiredo, Adrián M T Silva
Rising global energy demands associated to unbalanced allocation of water resources highlight the importance of water management solutions for the gas industry. Advanced drilling, completion and stimulation techniques for gas extraction, allow more economical access to unconventional gas reserves. This stimulated a shale gas revolution, besides tight gas and coalbed methane, also causing escalating water handling challenges in order to avoid a major impact on the environment. Hydraulic fracturing allied to horizontal drilling is gaining higher relevance in the exploration of unconventional gas reserves, but a large amount of wastewater (known as "produced water") is generated...
June 16, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28599208/occurrence-of-pharmaceutical-recreational-and-psychotropic-drug-residues-in-surface-water-on-the-northern-antarctic-peninsula-region
#3
Silvia González-Alonso, Luis Moreno Merino, Sara Esteban, Miren López de Alda, Damià Barceló, Juan José Durán, Jerónimo López-Martínez, Jaume Aceña, Sandra Pérez, Nicola Mastroianni, Adrián Silva, Myriam Catalá, Yolanda Valcárcel
Human presence in the Antarctic is increasing due to research activities and the rise in tourism. These activities contribute a number of potentially hazardous substances. The aim of this study is to conduct the first characterisation of the pharmaceuticals and recreational drugs present in the northern Antarctic Peninsula region, and to assess the potential environmental risk they pose to the environment. The study consisted of a single sampling of ten water samples from different sources, including streams, ponds, glacier drains, and a wastewater discharge into the sea...
June 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28580109/photoswitchable-interlocked-thiodiglycolamide-as-a-cocatalyst-of-a-chalcogeno-baylis-hillman-reaction
#4
Alberto Martinez-Cuezva, Adrian Saura-Sanmartin, Tomas Nicolas-Garcia, Cristian Navarro, Raul-Angel Orenes, Mateo Alajarin, Jose Berna
En route to a photoswitchable interlocked catalyst we have proved the ability of thiodiglycolamide to act as a template in the formation of hydrogen-bonded [2]rotaxanes. X-ray diffraction studies reveal the shielding of the sulfide atom by the macrocycle. A series of molecular shuttles are described as having an isomerizable fumaramide and thiodiglycolamide binding sites for controlling the relative ring position at will. By employing these systems as photoregulated catalysts, the TiCl4-mediated chalcogeno-Morita-Baylis-Hillman reaction is tested...
May 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28554112/wastewater-based-epidemiology-to-assess-pan-european-pesticide-exposure
#5
Nikolaos I Rousis, Emma Gracia-Lor, Ettore Zuccato, Richard Bade, Jose Antonio Baz-Lomba, Erika Castrignanò, Ana Causanilles, Adrian Covaci, Pim de Voogt, Félix Hernàndez, Barbara Kasprzyk-Hordern, Juliet Kinyua, Ann-Kathrin McCall, Benedek Gy Plósz, Pedram Ramin, Yeonsuk Ryu, Kevin V Thomas, Alexander van Nuijs, Zhugen Yang, Sara Castiglioni
Human biomonitoring, i.e. the determination of chemicals and/or their metabolites in human specimens, is the most common and potent tool for assessing human exposure to pesticides, but it suffers from limitations such as high costs and biases in sampling. Wastewater-based epidemiology (WBE) is an innovative approach based on the chemical analysis of specific human metabolic excretion products (biomarkers) in wastewater, and provides objective and real-time information on xenobiotics directly or indirectly ingested by a population...
May 21, 2017: Water Research
https://www.readbyqxmd.com/read/28549458/detection-of-alk-fusion-transcripts-in-ffpe-lung-cancer-samples-by-nanostring-technology
#6
Adriane F Evangelista, Maicon F Zanon, Adriana Cruvinel Carloni, Flávia E de Paula, Mariana Andozia Morini, Maressa Ferreira-Neto, Iberê Cauduro Soares, Jose Elias Miziara, Pedro de Marchi, Cristovam Scapulatempo-Neto, Rui M Reis
BACKGROUND: ALK-rearranged lung cancers exhibit specific pathologic and clinical features and are responsive to anti-ALK therapies. Therefore, the detection of ALK-rearrangement is fundamental for personalized lung cancer therapy. Recently, new molecular techniques, such as NanoString nCounter, have been developed to detect ALK fusions with more accuracy and sensitivity. METHODS: In the present study, we intended to validate a NanoString nCounter ALK-fusion panel in routine biopsies of FFPE lung cancer patients...
May 26, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28533560/saving-the-world-s-terrestrial-megafauna
#7
William J Ripple, Guillaume Chapron, José Vicente López-Bao, Sarah M Durant, David W Macdonald, Peter A Lindsey, Elizabeth L Bennett, Robert L Beschta, Jeremy T Bruskotter, Ahimsa Campos-Arceiz, Richard T Corlett, Chris T Darimont, Amy J Dickman, Rodolfo Dirzo, Holly T Dublin, James A Estes, Kristoffer T Everatt, Mauro Galetti, Varun R Goswami, Matt W Hayward, Simon Hedges, Michael Hoffmann, Luke T B Hunter, Graham I H Kerley, Mike Letnic, Taal Levi, Fiona Maisels, John C Morrison, Michael Paul Nelson, Thomas M Newsome, Luke Painter, Robert M Pringle, Christopher J Sandom, John Terborgh, Adrian Treves, Blaire Van Valkenburgh, John A Vucetich, Aaron J Wirsing, Arian D Wallach, Christopher Wolf, Rosie Woodroffe, Hillary Young, Li Zhang
No abstract text is available yet for this article.
October 1, 2016: Bioscience
https://www.readbyqxmd.com/read/28529205/effectiveness-and-safety-of-bedaquiline-containing-regimens-in-the-treatment-of-mdr-and-xdr-tb-a-multicentre-study
#8
Sergey E Borisov, Keertan Dheda, Martin Enwerem, Rodolfo Romero Leyet, Lia D'Ambrosio, Rosella Centis, Giovanni Sotgiu, Simon Tiberi, Jan-Willem Alffenaar, Andrey Maryandyshev, Evgeny Belilovski, Shashank Ganatra, Alena Skrahina, Onno Akkerman, Alena Aleksa, Rohit Amale, Janina Artsukevich, Judith Bruchfeld, Jose A Caminero, Isabel Carpena Martinez, Luigi Codecasa, Margareth Dalcolmo, Justin Denholm, Paul Douglas, Raquel Duarte, Aliasgar Esmail, Mohammed Fadul, Alexey Filippov, Lina Davies Forsman, Mina Gaga, Julia-Amaranta Garcia-Fuertes, José-María García-García, Gina Gualano, Jerker Jonsson, Heinke Kunst, Jillian S Lau, Barbara Lazaro Mastrapa, Jorge Lazaro Teran Troya, Selene Manga, Katerina Manika, Pablo González Montaner, Jai Mullerpattan, Suzette Oelofse, Martina Ortelli, Domingo Juan Palmero, Fabrizio Palmieri, Antonella Papalia, Apostolos Papavasileiou, Marie-Christine Payen, Emanuele Pontali, Carlos Robalo Cordeiro, Laura Saderi, Tsetan Dorji Sadutshang, Tatsiana Sanukevich, Varvara Solodovnikova, Antonio Spanevello, Sonam Topgyal, Federica Toscanini, Adrian R Tramontana, Zarir Farokh Udwadia, Pietro Viggiani, Veronica White, Alimuddin Zumla, Giovanni Battista Migliori
Large studies on bedaquiline used to treat multidrug-resistant (MDR-) and extensively drug-resistant tuberculosis (XDR-TB) are lacking. This study aimed to evaluate the safety and effectiveness of bedaquiline-containing regimens in a large, retrospective, observational study conducted in 25 centres and 15 countries in five continents.428 culture-confirmed MDR-TB cases were analysed (61.5% male; 22.1% HIV-positive, 45.6% XDR-TB). MDR-TB cases were admitted to hospital for a median (interquartile range (IQR)) 179 (92-280) days and exposed to bedaquiline for 168 (86-180) days...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28512728/treatment-of-red-tattoo-reaction-using-co2-laser
#9
José Francisco Millán-Cayetano, Adrián Alegre-Sánchez, Pablo Boixeda
No abstract text is available yet for this article.
May 17, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28510631/how-might-edaphic-specialists-in-gypsum-islands-respond-to-climate-change-reciprocal-sowing-experiment-to-infer-local-adaptation-and-phenotypic-plasticity
#10
Ana M Sánchez, Patricia Alonso-Valiente, M José Albert, Adrián Escudero
Background and Aims: Local adaptation and phenotypic plasticity are considered key mechanisms for coping with climate warming, especially for plant species that inhabit island-like habitats. In Spain a complete guild of edaphic specialists, most of them threatened, occurs in gypsum outcrops, but how these species will respond to climate change has received little attention. Methods: A reciprocal sowing experiment was performed to determine the extent of local adaptation and phenotypic plasticity in five gypsophytes with contrasting distributions along a climate gradient...
May 16, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28504450/the-influence-of-environmental-management-and-animal-shelters-in-vector-control-of-culicoides-diptera-ceratopogonidae-in-northeastern-brazil
#11
Maria da C A Bandeira, Gustavo A Brito, Adriane da Penha, Ciro L C Santos, José M M Rebêlo
We investigated whether biting midges in peridomestic environments are affected by environmental management practices and the presence of domestic animals. We used CDC light traps to collect midges in 112 residences across 24 locations along tourism routes of Maranhão, Brazil. The collection areas were characterized as follows: i) peridomestic area with domestic animals and without management (dirty); ii) peridomestic with domestic animals and management (clean); iii) peridomestic without animals and with management (clean); iv) peridomestic without animals and without management (dirty)...
June 2017: Journal of Vector Ecology: Journal of the Society for Vector Ecology
https://www.readbyqxmd.com/read/28498784/depth-of-response-in-multiple-myeloma-a-pooled-analysis-of-three-pethema-gem-clinical-trials
#12
Juan-Jose Lahuerta, Bruno Paiva, Maria-Belen Vidriales, Lourdes Cordón, Maria-Teresa Cedena, Noemi Puig, Joaquin Martinez-Lopez, Laura Rosiñol, Norma C Gutierrez, María-Luisa Martín-Ramos, Albert Oriol, Ana-Isabel Teruel, María-Asunción Echeveste, Raquel de Paz, Felipe de Arriba, Miguel T Hernandez, Luis Palomera, Rafael Martinez, Alejandro Martin, Adrian Alegre, Javier De la Rubia, Alberto Orfao, María-Victoria Mateos, Joan Blade, Jesus F San-Miguel
Purpose To perform a critical analysis on the impact of depth of response in newly diagnosed multiple myeloma (MM). Patients and Methods Data were analyzed from 609 patients who were enrolled in the GEM (Grupo Español de Mieloma) 2000 and GEM2005MENOS65 studies for transplant-eligible MM and the GEM2010MAS65 clinical trial for elderly patients with MM who had minimal residual disease (MRD) assessments 9 months after study enrollment. Median follow-up of the series was 71 months. Results Achievement of complete remission (CR) in the absence of MRD negativity was not associated with prolonged progression-free survival (PFS) and overall survival (OS) compared with near-CR or partial response (median PFS, 27, 27, and 29 months, respectively; median OS, 59, 64, and 65 months, respectively)...
May 12, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28490061/the-inclusion-complex-of-oxyresveratrol-in-modified-cyclodextrins-a-thermodynamic-structural-physicochemical-fluorescent-and-computational-study
#13
Adrián Matencio, Francisco García-Carmona, José Manuel López-Nicolás
The interaction between oxyresveratrol (a type of stilbene with high biological activity) and modified cyclodextrins (CDs) was studied. Using HPLC-RP, was seen to form a 1:1 complex with all the CDs tested. The best CD in this respect was MβCD (KF=606.65±30.18M(-1)), the complexation showing a strong dependence on pH and temperature: The complexation constant (KF) decreased as the pH and temperature increased. The thermodynamic parameters studied (ΔH°, ΔS° and ΔG°) showed negative entropy, enthalpy and Gibbs free energy change at 25°C...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28487577/nasal-swab-results-for-methicillin-resistant-staphylococcus-aureus-and-associated-infections
#14
Josée Rioux, Jenny Edwards, Lauren Bresee, Adrian Abu-Ulba, Stephen Yu, Deonne Dersch-Mills, Ben Wilson
BACKGROUND: Nasal-swab screening for methicillin-resistant Staphylococcus aureus (MRSA) has a quicker turnaround time than other bacterial culture methods, with results available within 24 h. Although MRSA nasal-swab screening is not intended to guide antimicrobial therapy, this method may give clinicians additional information for earlier tailoring of empiric antimicrobial agents. OBJECTIVE: To describe the diagnostic characteristics of nasal-swab screening in predicting MRSA infections in hospitalized patients receiving empiric treatment with IV vancomycin...
March 2017: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/28486430/characterization-of-copy-number-variation-s-potential-role-in-marek-s-disease
#15
Lingyang Xu, Yanghua He, Yi Ding, Guirong Sun, Jose Adrian Carrillo, Yaokun Li, Mona M Ghaly, Li Ma, Huanmin Zhang, George E Liu, Jiuzhou Song
Marek's Disease (MD) is a highly contagious pathogenic and oncogenic disease primarily affecting chickens. Chicken Lines 63 and 72, as well as their recombinant congenic strains (RCS) with varied susceptibility to MD, are ideal models to study the complex mechanisms of genetic resistance to MD. In this study, we investigated copy number variation (CNV) in these inbred chicken lines using the Affymetrix Axiom HD 600 K SNP genotyping array. We detected 393 CNV segments across all ten chicken lines, of which 12 CNVs were specifically identified in Line 72...
May 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28469108/vascular-calcification-current-genetics-underlying-this-complex-phenomenon
#16
REVIEW
Nonanzit Pérez-Hernández, Gad Aptilon-Duque, Ruben Blachman-Braun, Gilberto Vargas-Alarcón, Adrián Asael Rodríguez-Cortés, Shely Azrad-Daniel, Rosalinda Posadas-Sánchez, José Manuel Rodríguez-Pérez
OBJECTIVE: Vascular calcification is the consequence of the complex interaction between genetic, environmental, and vascular factors, which ultimately lead to the deposition of calcium in the tunica intima (atherosclerotic calcification) or tunica media (Mönckenberg's sclerosis). Vascular calcification is also closely related to other pathologies, such as diabetes mellitus, dyslipidemia, and chronic kidney disease. It has been concluded that the degree of vascular calcification may vary from person to person, even if the associated pathologies and environmental factors are the same...
May 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28458819/mesenteric-intranodal-schwannoma-uncommon-case-of-neurogenic-benign-tumor
#17
Adrian Medina-Gallardo, Yuhamy Curbelo-Peña, Jose Molinero-Polo, Maria Saladich-Cubero, Xavier De Castro-Gutierrez, Helena Vallverdú-Cartie
Intranodal schawnomas are extremely rare. Just a few cases have been described before. Clinical presentation comprises not only symptomatic mass in several anatomical body parts, but also, they can be found during analysis of surgical specimens resected for other reasons. The report is based on the case of an 80-year-old patient who underwent to right hemicolectomy for an adenocarcinoma. The histopathologic analysis revealed one mesenteric intranodal schwannoma in the surgical specimen. The diagnosis was confirmed by immunohistochemistry with positive result for vimentin and S100 protein...
February 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28447618/manufacturing-differences-affect-human-bone-marrow-stromal-cell-characteristics-and-function-comparison-of-production-methods-and-products-from-multiple-centers
#18
Shutong Liu, Luis F de Castro, Ping Jin, Sara Civini, Jiaqiang Ren, Jo-Anna Reems, Jose Cancelas, Ramesh Nayak, Georgina Shaw, Timothy O'Brien, David H McKenna, Myriam Armant, Leslie Silberstein, Adrian P Gee, Derek J Hei, Peiman Hematti, Sergei A Kuznetsov, Pamela G Robey, David F Stroncek
Human bone marrow stromal cells (BMSCs, also known as bone marrow-derived mesenchymal stem cells) are manufactured using many different methods, but little is known about the spectrum of manufacturing methods used and their effects on BMSC characteristics and function. Seven centers using, and one developing, Good Manufacturing Practices (GMP) processes were surveyed as to their production methods. Among the seven centers, all used marrow aspirates as the starting material, but no two centers used the same manufacturing methods...
April 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28441001/-mexican-asthma-guidelines-guima-2017
#19
Désirée Larenas-Linnemann, Jorge Salas-Hernández, Juan Carlos Vázquez-García, Ignacio Ortiz-Aldana, Margarita Fernández-Vega, Blanca Estela Del Río-Navarro, María Del Carmen Cano-Salas, Jorge Agustín Luna-Pech, José Antonio Ortega-Martell, Jade Romero-Lombard, Erika Del Carmen López-Estrada, Jimena Villaverde-Rosas, José Luis Mayorga-Butrón, Mario Humberto Vargas-Becerra, Martín Bedolla-Barajas, Noel Rodríguez-Pérez, Ambrocio Aguilar-Aranda, Carlos Adrián Jiménez-González, Carlos García-Bolaños, Claudia Garrido-Galindo, David Alejandro Mendoza-Hernández, Enrique Mendoza-López, Gerardo López-Pérez, Guillermo Hideo Wakida-Kuzonoki, Héctor Hernán Ruiz-Gutiérrez, Héctor León-Molina, Héctor Martínez-De la Lanza, Héctor Stone-Aguilar, Javier Gómez-Vera, Jorge Olvera-Salinas, José Joel Oyoqui-Flores, José Luis Gálvez-Romero, José Santos Lozano-Sáenz, Juan Ignacio Salgado-Gama, Marcos Alejandro Jiménez-Chobillon, Martha Angélica García-Avilés, Martha Patricia Guinto-Balanzar, Miguel Alejandro Medina-Ávalos, Robert Camargo-Angeles, Rogelio García-Torrentera, Saraí Toral-Freyre, Gabriel Montes-Narváez, Héctor Solorio-Gómez, Juan Rosas-Peña, Sergio Jesús Romero-Tapia, Adela Reyes-Herrera, Francisco Cuevas-Schacht, Joaquín Esquer-Flores, José Antonio Sacre-Hazouri, Lorenzo Compean-Martínez, Pablo Julián Medina-Sánchez, Sergio Garza-Salinas, Carlos Báez-Loyola, Iraís Romero-Alvarado, José Luis Miguel-Reyes, Laura Elizabeth Huerta-Espinosa, Manuel Ángel Correa-Flores, Ricardo Castro-Martínez
BACKGROUND: The need for a national guideline, with a broad basis among specialists and primary care physicians was felt in Mexico, to try unifying asthma management. As several high-quality asthma guidelines exist worldwide, it was decided to select the best three for transculturation. METHODS: Following the internationally recommended methodology for guideline transculturation, ADAPTE, a literature search for asthma guidelines, published 1-1-2007 through 31-12-2015 was conducted...
2017: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/28406624/flame-retardant-chemicals-in-college-dormitories-flammability-standards-influence-dust-concentrations
#20
Robin E Dodson, Kathryn M Rodgers, Gale Carey, Jose Guillermo Cedeno Laurent, Adrian Covaci, Giulia Poma, Govindan Malarvannan, John D Spengler, Ruthann A Rudel, Joseph G Allen
Furniture flammability standards are typically met with chemical flame retardants (FRs). FRs can migrate out of products into dust and are linked to cancer, neurological impairment, and endocrine disruption. We collected 95 dust samples from dormitory common areas and student rooms on two U.S. college campuses adhering to two different furniture flammability standards: Technical Bulletin 117 (TB117) and Technical Bulletin 133 (TB133). Because TB133 requires furniture to withstand a much-more-demanding test flame than TB117, we hypothesized that spaces with TB133 furniture would have higher levels of FRs in dust...
May 2, 2017: Environmental Science & Technology
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