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https://www.readbyqxmd.com/read/29044206/emergence-of-the-stoner-wohlfarth-astroid-in-thin-films-at-dynamic-regime
#1
José Luis F Cuñado, Alberto Bollero, Tomás Pérez-Castañeda, Paolo Perna, Fernando Ajejas, Javier Pedrosa, Adrian Gudín, Ana Maldonado, Miguel Angel Niño, Rubén Guerrero, David Cabrera, Francisco J Terán, Rodolfo Miranda, Julio Camarero
The Stoner-Wohlfarth (SW) model is the simplest model that describes adequately the magnetization reversal of nanoscale systems that are small enough to contain single magnetic domains. However for larger sizes where multi-domain effects are present, e.g., in thin films, this simple macrospin approximation fails and the experimental critical curve, referred as SW astroid, is far from its predictions. Here we show that this discrepancy could vanish also in extended system. We present a detailed angular-dependent study of magnetization reversal dynamics of a thin film with well-defined uniaxial magnetic anisotropy, performed over 9 decades of applied field sweep rate (dH/dt)...
October 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29042175/calcitriol-promotes-proangiogenic-molecules-in-keratinocytes-in-a-diabetic-foot-ulcer-model
#2
Valentin Trujillo, Paulina Marín-Luevano, Irma González-Curiel, Adrián Rodríguez-Carlos, Maira Ramírez-Reyes, Esther Layseca-Espinosa, José A Enciso-Moreno, Lorenza Díaz, Bruno Rivas-Santiago
Foot ulceration is one of the most common and complex sequelae of diabetes mellitus, generally posing a therapeutic challenge due to poor healing responses and high rates of complications, including peripheral vascular disease, ischemia and infections. Calcitriol, the most active vitamin D metabolite, induces antimicrobial peptides production in keratinocytes from diabetic foot ulcers (DFU); however, little is known about its effects on angiogenic factors in this pathology. Herein we aimed at studying whether calcitriol induces angiogenic molecules in keratinocytes under normoxic and hypoxic conditions, and if these molecules are able to improve cell migration in vitro...
October 14, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29027574/the-prognostic-significance-of-serum-xcl1-concentration-in-patients-with-acute-lymphoblastic-leukemia-a-pilot-study
#3
Cesar Homero Gutiérrez-Aguirre, Juan Antonio Flores-Jiménez, Julio Alatorre-Ricardo, Olga Graciela Cantú-Rodríguez, Adrián Rosas-Taraco, Rosario Salazar-Riojas, José Carlos Jaime-Pérez, Mónica Sánchez-Cárdenas, Leslie López-Silva, Azalia M Martínez-Castilla, Mario Cesar Salinas-Carmona, David Gómez-Almaguer
There is no information about XCL1 in patients with acute lymphoblastic leukemia (ALL). The objective of this study was to correlate the serum levels of XCL1 and survival in ALL patients. Only ALL patients older than 12 months were considered to participate. Serum XCL1 was measured at diagnosis, end of remission induction, and end of consolidation. Thirty-three ALL patients with median age of 21 years (1-78) were included. Higher XCL1 level (above 50 pg/mL) at ALL diagnosis correlated with higher survival (p = 0...
October 13, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/29023801/influence-of-genotype-and-crop-year-in-the-chemometrics-of-almond-and-pistachio-oils
#4
Adrián Rabadán, Manuel Álvarez, Ricardo Gómez, Concepción de Miguel, José E Pardo
BACKGROUND: Almond and pistachio oils can be considered as interesting products to produce and commercialize due to their health promoting properties. However, these properties are not consistent because of the differences that appear in oils as a result of the genotype and the crop year. The analysis of these variations and their origin is decisive to ensure the commercial future prospects of these nut oils. RESULTS: Although significant variability has been reported in almond and pistachio oils as a result of the crop year and the interaction between the crop year and the genotype, the genotype itself remains as the main factor determining oil chemometrics...
October 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29020360/epidemiology-clinical-features-and-outcome-of-infective-endocarditis-due-to-abiotrophia-spp-and-granulicatella-spp-report-of-76-cases-2000-2015
#5
Adrián Téllez, Juan Ambrosioni, Jaume Llopis, Juan M Pericàs, Carles Falces, Manel Almela, Cristina Garcia de la Mària, Marta Hernandez-Meneses, Bàrbara Vidal, Elena Sandoval, Eduard Quintana, David Fuster, José M Tolosana, Francesc Marco, Asunción Moreno, José M Miro
Background: Infective endocarditis (IE) caused by Abiotrophia (ABI) and Granulicatella (GRA) is poorly studied. This work aims to describe and compare the main features of ABI and GRA IE. Methods: We performed a retrospective study of 12 IE institutional cases of GRA or ABI and of 64 cases published in the literature (overall, 38 ABI and 38 GRA IE cases). Results: ABI/GRA IE represented 1.51% of IE cases in our institution between 2000-2015, compared to 0...
August 19, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29020293/dual-therapy-with-darunavir-and-ritonavir-plus-lamivudine-versus-triple-therapy-with-darunavir-and-ritonavir-plus-tenofovir-disoproxil-fumarate-and-emtricitabine-or-abacavir-and-lamivudine-for-maintenance-of-hiv-1-viral-suppression-randomised-open-label-non
#6
Federico Pulido, Esteban Ribera, María Lagarde, Ignacio Pérez-Valero, Rosario Palacios, José A Iribarren, Antoni Payeras, Pere Domingo, José Sanz, Miguel Cervero, Adrián Curran, Francisco J Rodríguez-Gómez, María J Téllez, Pablo Ryan, Pilar Barrufet, Hernando Knobel, Antonio Rivero, Belén Alejos, María Yllescas, José R Arribas
Background: Our objective was to assess the therapeutic non-inferiority of dual therapy with darunavir/ritonavir and lamivudine compared to triple therapy with darunavir/ritonavir plus tenofovir disoproxil fumarate and emtricitabine or abacavir and lamivudine for maintenance of HIV-1 viral suppression. Methods: 48-week, multicenter, open-label, non-inferiority trial (margin 12%). Patients with HIV-1 RNA <50 copies/mL for ≥6 months on triple therapy with darunavir/ritonavir and two nucleos(t)ides (tenofovir disoproxil fumarate and emtricitabine or abacavir and lamivudine), with no resistance, were randomized to continue therapy (n=128) or switch to darunavir/ritonavir and lamivudine (n=129)...
August 17, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29018481/comparative-study-between-plastic-and-metallic-stents-for-biliary-decompression-in-patients-with-distal-biliary-obstruction
#7
João Guilherme G Cabral, Eloy Taglieri, Adriane Pelosof, Daniel Rosendo, José Celso Ardengh
This paper presents a retrospective comparison of plastic versus metallic stents in the drainage of malignant distal biliary obstructions. We compared single plastic stents (SPS), multiple plastic stents (MPS), and metallic stents (SEMS) regarding clinical decrease of TB < 2.0 mg/dL, long-term patency, and adverse event. 58 patients (38 women) with MDBO were included. Diagnoses were 44 pancreatic adenocarcinoma (74.6%), 9 metastasis (15.5%), 3 pancreatic neuroendocrine tumors (5.1%), and 2 adenocarcinoma in the major papilla (3...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28979780/lesinurad-what-the-nephrologist-should-know
#8
Maria Dolores Sanchez-Niño, Binbin Zheng-Lin, Lara Valiño-Rivas, Ana Belen Sanz, Adrian Mario Ramos, Jose Luño, Marian Goicoechea, Alberto Ortiz
Lesinurad is an oral inhibitor of the monocarboxylic/urate transporter URAT1 encoded by the SLC22A12 gene. Market authorization was granted in February 2016 in Europe and December 2015 in the USA. As a potentially nephrotoxic uricosuric drug acting on the kidney, nephrologists should become familiar with its indications and safety profile. The approved indication is treatment of gout in combination with a xanthine oxidase (XO) inhibitor in adult patients who have not achieved target serum uric acid levels with an XO inhibitor alone...
October 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28979236/optic-neuropathy-secondary-to-polyarteritis-nodosa-case-report-and-diagnostic-challenges
#9
Kristian A Vazquez-Romo, Adrian Rodriguez-Hernandez, Jose A Paczka, Moises A Nuño-Suarez, Alberto D Rocha-Muñoz, Maria G Zavala-Cerna
PURPOSE: To describe a case of optic neuropathy as a primary manifestation of polyarteritis nodosa (PAN) and discuss diagnostic challenges. METHODS: Case report. RESULTS: A 41-year-old Hispanic man presented with a 2-day history of reduced visual acuity in his left eye. Physical examination revealed a complete visual field loss in the affected eye. Best-corrected visual acuity (BCVA) in the left eye was hand motion, and fundus examination revealed a hyperemic optic disk with blurred margins, swelling, retinal folds, dilated veins, and normal size arteries...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28979106/acute-strength-training-promotes-responses-in-whole-blood-circulating-levels-of-mir-146a-among-older-adults-with-type-2-diabetes-mellitus
#10
Gilberto Santos Morais Junior, Vinicius Carolino Souza, Wilcelly Machado-Silva, Adriane Dallanora Henriques, Andressa Melo Alves, Danilo Barbosa Morais, Otávio Toledo Nóbrega, Ciro José Brito, Roberto Jerônimo Dos Santos Silva
Type 2 diabetes mellitus (T2DM) consists of a set of metabolic and endocrine disorders which evolve into deficiency in insulin action and hyperglycemia. Physical exercise is considered the main intervention to prevent and control T2DM. Literature has suggested that circulating microRNAs (miRs) help to understand responses to physical activity among diabetic patients. Thus, the aim of this study was to analyze the acute effect of two interventions (strength and cardiovascular) on the total, whole blood circulating concentrations of miR-126, miR-146a and miR-155 in older adults with and without T2DM...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28976491/genetic-variants-and-hamstring-injury-in-soccer-an-association-and-validation-study
#11
Jon Larruskain, David Celorrio, Irantzu Barrio, Adrian Odriozola, Susana M Gil, Juan Ramon Fernandez-Lopez, Raul Nozal, Isusko Ortuzar, Jose A Lekue, Jose M Aznar
PURPOSE: To investigate the association of candidate single nucleotide polymorphisms (SNPs) with non-contact hamstring muscle injuries in elite soccer players, and to create and validate a model to assess the risk of hamstring injury. METHODS: 107 elite male outfield players were prospectively followed for 6 seasons. Players were genotyped for 37 SNPs previously investigated in relation to musculoskeletal injuries. The association of SNPs, previous injury, age, level of play, position and anthropometric data with 129 hamstring injuries (413 observations) was investigated in the discovery phase (2010-2015), and a multivariable Cox-frailty model was created using forward selection...
October 2, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28971542/scipion-web-tools-easy-to-use-cryo-em-image-processing-over-the-web
#12
Pablo Conesa Mingo, José Gutierrez, Adrián Quintana, José Miguel de la Rosa Trevín, Airén Zaldívar-Peraza, Jesús Cuenca Alba, Moshen Kazemi, Javier Vargas, Laura Del Cano, Joan Segura, Carlos Oscar S Sorzano, Jose María Carazo
Macromolecular structural determination by Electron Microscopy under cryogenic conditions is revolutionizing the field of structural biology, interesting a large community of potential users. Still, the path from raw images to density maps is complex, and sophisticated image processing suites are required in this process, often demanding the installation and understanding of different software packages. Here we present Scipion Web Tools, a web-based set of tools/workflows derived from the Scipion image processing framework, specially tailored to non-expert users in need of very precise answers at several key stages of the structural elucidation process...
October 3, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28971503/high-dose-chemotherapy-and-autologous-stem-cell-transplantation-in-nodular-lymphocyte-predominant-hodgkin-lymphoma-a-retrospective-study-by-the-european-society-for-blood-and-marrow-transplantation-ebmt-lymphoma-working-party
#13
Saad Akhtar, Silvia Montoto, Ariane Boumendil, Herve Finel, Tamas Masszi, Pavel Jindra, Damir Nemet, Stephan Fuhrmann, Yves Beguin, Luca Castagna, Felicetto Ferrara, Saveria Capria, Ram Malladi, Jose Maria Moraleda, Adrian Bloor, Hervé Ghesquières, Julia Meissner, Anna Sureda, Peter Dreger
Whilst autologous stem cell transplantation (auto-SCT) is considered standard of care for relapsed/refractory classical Hodgkin lymphoma, the role of auto-SCT in nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is not well defined due to limited data. We report the first study on auto-SCT for NLPHL with a larger cohort. Eligible for this retrospective registry study were patients reported to the EBMT between 2003-2013, aged 18 or older with relapsed/refractory NLPHL who underwent first auto-SCT with disease chemosensitive to salvage therapy...
October 3, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28962998/direct-identification-of-clinical-pathogens-from-liquid-culture-media-by-maldi-tof-ms-analysis
#14
Marina Oviaño, Belén Rodríguez-Sánchez, Marta Gómara, Luis Alcalá, Estrella Zvezdanova, Adrián Ruíz, David Velasco, María José Gude, Emilio Bouza, Germán Bou
OBJECTIVES: We propose using MALDI-TOF MS as a tool for identifying microorganisms directly from liquid cultures after enrichment of the clinical sample in the media, in order to obtain a rapid microbiological diagnosis and an adequate administration of the antibiotic therapy in a clinical setting. METHODS: To evaluate this approach, a series of quality control isolates, were grown in thioglycollate (TG) broth and brain heart infusion (BHI) broth and extracted under 4 different protocols before finally being identified by MALDI-TOF MS...
September 26, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28941945/accuracy-of-the-ultra-rapid-urease-test-for-diagnosis-of-helicobacter-pylori-infection
#15
Adrian Gerald McNicholl, Julio Ducons, Jesús Barrio, Luis Bujanda, Montserrat Forné-Bardera, Reyes Aparcero, Julio Ponce, Robin Rivera, José María Dedeu-Cuso, Pilar Garcia-Iglesias, Miguel Montoro, Alicia Bejerano, Yolanda Ber-Nieto, Belen Madrigal, Eva Zapata, Carmen Loras-Alastruey, Manuel Castro, Andrea Nevarez, Isabel Mendez, Felipe Bory-Ros, Mireia Miquel-Planas, Isabel Vera, Olga P Nyssen, Javier P Gisbert
BACKGROUND: Rapid Urease Test (RUT) is a simple, cheap and relatively fast method for diagnosing Helicobacter pylori infection. It is therefore the preferred method used for patients undergoing gastroscopy. Most kits require 24h to give results. The new Ultra-Rapid Urease Test (URUT) kit by Biohit® requires less than 1h. OBJECTIVE: To determine URUT's diagnostic accuracy. METHOD: Prospective, blind, multi-centre study involving dyspeptic patients...
September 21, 2017: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/28923896/experimental-and-theoretical-approaches-to-investigate-the-immunogenicity-of-taenia-solium-derived-ke7-antigen
#16
Raúl J Bobes, José Navarrete-Perea, Adrián Ochoa-Leyva, Víctor Hugo Anaya, Marisela Hernández, Jacquelynne Cervantes-Torres, Karel Estrada, Filiberto Sánchez-Lopez, Xavier Soberón, Gabriela Rosas, Cáris Maroni Nunes, Martín García-Varela, Rogerio Rafael Sotelo-Mundo, Alonso Alexis López-Zavala, Goar Gevorkian, Gonzalo Acero, Juan P Laclette, Gladis Fragoso, Edda Sciutto
Taenia solium cysticercosis, a parasitic disease that affects human health in various regions of the world, is preventable by vaccination. Both the 97-amino-acid-long KETc7 peptide and its carboxyl-terminal, 18-amino-acid-long sequence (GK-1) are found in Taenia crassiceps Both peptides, with proven protective capacity against cysticercosis, are part of the highly conserved, cestode-native, 264-amino-acid long protein KE7. KE7 belongs to a ubiquitously distributed family of proteins associated to membrane processes and may participate in several vital cell pathways...
September 18, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28923171/potential-early-biomarkers-of-sarcopenia-among-independent-older-adults
#17
Ana Coto Montes, José Antonio Boga, Carlos Bermejo Millo, Adrián Rubio González, Yaiza Potes Ochoa, Ignacio Vega Naredo, Marta Martínez Reig, Luis Romero Rizos, Pedro Manuel Sánchez Jurado, Juan Jose Solano, Pedro Abizanda, Beatriz Caballero
OBJECTIVES: There are no tools or biomarkers for a quantitative analysis of sarcopenia. STUDY DESIGN: Cross-sectional study of the diagnosis of sarcopenia in 200 independent adults aged 70 years or over. MAIN OUTCOME MEASURES: Sarcopenia was defined as loss of muscle mass together with low strength and/or loss of physical performance. We considered different clinical parameters and assayed potential blood biomarkers (cell energetic metabolism, muscle performance, inflammation, infection and oxidative stress)...
October 2017: Maturitas
https://www.readbyqxmd.com/read/28878860/draft-genome-sequences-of-two-opportunistic-pathogenic-strains-of-staphylococcus-cohnii-isolated-from-human-patients
#18
Soraya Mendoza-Olazarán, José F Garcia-Mazcorro, Rayo Morfín-Otero, Licet Villarreal-Treviño, Adrián Camacho-Ortiz, Eduardo Rodríguez-Noriega, Paola Bocanegra-Ibarias, Héctor J Maldonado-Garza, Scot E Dowd, Elvira Garza-González
Herein, we report the draft-genome sequences and annotation of two opportunistic pathogenic strains of Staphylococcus cohnii isolated from humans. One strain (SC-57) was isolated from blood from a male patient in May 2006 and the other (SC-532) from a catheter from a male patient in June 2006. Similar to other genomes of Staphylococcus species, most genes (42%) of both strains are involved in metabolism of amino acids and derivatives, carbohydrates and proteins. Eighty (4%) genes are involved in virulence, disease, and defense and both species show phenotypic low biofilm production and evidence of increased antibiotic resistance associated to biofilm production...
2017: Standards in Genomic Sciences
https://www.readbyqxmd.com/read/28873230/effect-of-roasting-conditions-on-the-composition-and-antioxidant-properties-of-defatted-walnut-flour
#19
Joana Santos, Manuel Alvarez-Ortí, Estela Sena-Moreno, Adrián Rabadán, José E Pardo, M Beatriz P P Oliveira
BACKGROUND: The walnut oil extraction by pressure systems, produces a press cake as a by-product, with many of the beneficial walnut properties. The objective of this work was to evaluate the composition and the antioxidant properties of walnut flours submitted to different roasting protocols (50, 100 and 150 °C during 30, 60 and 120 minutes). RESULTS: All walnut flours had about 42% of protein and a significant amount of dietary fibre (17%), not being affected by the roasting process...
September 5, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28852090/synthesis-and-characterization-of-ptte2-multi-crystallite-nanoparticles-using-organotellurium-nanocomposites
#20
Javier Fernández-Lodeiro, Benito Rodríguez-Gónzalez, Fernando Novio, Adrián Fernández-Lodeiro, Daniel Ruiz-Molina, José Luis Capelo, Alcindo A Dos Santos, Carlos Lodeiro
Herein, we report the synthesis of new PtTe2 multi-crystallite nanoparticles (NPs) in different sizes through an annealing process using new nanostructured Pt-Te organometallic NPs as a single source precursor. This precursor was obtained in a single reaction step using Ph2Te2 and H2PtCl6 and could be successfully size controlled in the nanoscale range. The resulting organometallic composite precursor could be thermally decomposed in 1,5 pentanediol to yield the new PtTe2 multi-crystallite NPs. The final size of the multi-crystallite spheres was successfully controlled by selecting the nanoprecursor size...
August 29, 2017: Scientific Reports
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