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https://www.readbyqxmd.com/read/28442229/changing-attitudes-to-childhood-immunisation-in-english-parents
#1
Helen Campbell, Angela Edwards, Louise Letley, Helen Bedford, Mary Ramsay, Joanne Yarwood
OBJECTIVES: We undertook a national survey of parental attitudes to childhood vaccinations and compared results with those in earlier comparable surveys covering a 10year period. METHODS: We randomly selected 275 nationally representative sampling locations in England. Interviewers identified eligible primary care givers (referred to as parents) of children aged from 2months to <5years and conducted home-based interviews between January and April 2015. We aimed to recruit 1000 parents of children aged 0-2years and 1000 of children aged 3-4years...
April 17, 2017: Vaccine
https://www.readbyqxmd.com/read/28435474/the-vision-of-industrie-4-0-in-the-making-a-case-of-future-told-tamed-and-traded
#2
Sabine Pfeiffer
Since industrial trade fair Hannover Messe 2011, the term "Industrie 4.0" has ignited a vision of a new Industrial Revolution and has been inspiring a lively, ongoing debate among the German public about the future of work, and hence society, ever since. The discourse around this vision of the future eventually spread to other countries, with public awareness reaching a temporary peak in 2016 when the World Economic Forum's meeting in Davos was held with the motto "Mastering the Fourth Industrial Revolution...
2017: Nanoethics
https://www.readbyqxmd.com/read/28433776/increasing-water-intake-in-pre-school-children-with-unhealthy-drinking-habits-a-year-long-controlled-longitudinal-field-experiment-assessing-the-impact-of-information-water-affordance-and-social-regulation
#3
Bradley Franks, Saadi Lahlou, Jeanne H Bottin, Isabelle Guelinckx, Sabine Boesen-Mariani
OBJECTIVE: We investigated the effect of three interventions to increase the plain water consumption of children with unhealthy drinking habits, with an innovative approach combining the three layers of Installation Theory: embodied competences, affordances and social regulation. METHODS: 334 preschool children and their carers were allocated to three interventions: Control (control): no intervention, Information (info): online coaching sessions on water health benefits aiming at modifying embodied competences (knowledge), Information + Water Affordance (info + w): the same plus home delivery of small bottles of water...
April 19, 2017: Appetite
https://www.readbyqxmd.com/read/28433403/-public-health-competencies-and-contents-in-spanish-university-degree-programmes-of-veterinary-medicine
#4
María Del Carmen Davó-Blanes, Carmen Vives-Cases, Belén Huerta
OBJECTIVE: To reach a consensus among public health faculty from various Spanish universities about the core public health competencies that should be integrated into the Veterinary Medicine degree training. METHODS: The 3rd Forum of University Professors of Public Health was held at the School of Veterinary Medicine of the University of Cordoba (12-13 January 2016). Forty-two university professors and lecturers from nine Spanish universities with veterinary degrees participated in the forum...
April 19, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28425650/current-strategies-for-endoscopic-management-of-acute-cholangitis
#5
Hiroyuki Isayama, Ichiro Yasuda, Damien Tan
BACKGROUND AND AIM: At the pancreatobiliary session of Endoscopic Forum Japan (EFJ) 2016, current strategies for the endoscopic management of acute cholangitis were discussed. The topics consisted of two major parts, namely endoscopic management of acute cholangitis caused by common bile duct stones (CBDS) and biliary stent occlusion. METHODS: Endoscopists from nine Japanese high-volume centers along with two overseas centers participated in the questionnaires and discussion...
April 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28423840/discovering-central-practitioners-in-a-medical-discussion-forum-using-semantic-web-analytics
#6
Enayat Rajabi, Syed Sibte Raza Abidi
The aim of this paper is to investigate semantic web based methods to enrich and transform a medical discussion forum in order to perform semantics-driven social network analysis. We use the centrality measures as well as semantic similarity metrics to identify the most influential practitioners within a discussion forum. The centrality results of our approach are in line with centrality measures produced by traditional SNA methods, thus validating the applicability of semantic web based methods for SNA, particularly for analyzing social networks for specialized discussion forums...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28421966/regulatory-forum-review-utility-of-in-vitro-secondary-pharmacology-data-to-assess-risk-of-drug-induced-valvular-heart-disease-in-humans-regulatory-considerations
#7
Thomas Papoian, Gowraganahalli Jagadeesh, Muriel Saulnier, Natalie Simpson, Arippa Ravindran, Baichun Yang, Adebayo A Laniyonu, Imran Khan, Ana Szarfman
Drug-induced valvular heart disease (VHD) is a serious side effect linked to long-term treatment with 5-hydroxytryptamine (serotonin) receptor 2B (5-HT2B) agonists. Safety assessment for off-target pharmacodynamic activity is a common approach used to screen drugs for this undesired property. Such studies include in vitro assays to determine whether the drug is a 5-HT2B agonist, a necessary pharmacological property for development of VHD. Measures of in vitro binding affinity (IC50, Ki) or cellular functional activity (EC50) are often compared to maximum therapeutic free plasma drug levels ( fCmax) from which safety margins (SMs) can be derived...
April 2017: Toxicologic Pathology
https://www.readbyqxmd.com/read/28421461/the-role-of-tumor-board-conferences-in-neuro-oncology-a-nationwide-provider-survey
#8
REVIEW
James Snyder, Lonni Schultz, Tobias Walbert
The tumor board or multidisciplinary cancer meeting (MCM) is the foundation of high value multidisciplinary oncology care, coordinating teams of specialists. Little is known on how these meetings are implemented in Neuro-oncology. Benefits of MCMs include coordination, direction for complicated cases, education, and a forum for communication, emerging technology, and clinical trials. This study identifies participation and utilization of neuro-oncology MCMs. A cross-sectional descriptive survey was dispersed through an internet questionnaire...
April 18, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28418689/an-official-american-thoracic-society-workshop-report-chemical-inhalational-disasters-biology-of-lung-injury-development-of-novel-therapeutics-and-medical-preparedness
#9
Eleanor M Summerhill, Gary W Hoyle, Sven-Eric Jordt, Bronwen J Jugg, James G Martin, Sadis Matalon, Steven E Patterson, David J Prezant, Alfred M Sciuto, Erik R Svendsen, Carl W White, Livia A Veress
This report is based upon the proceedings from the Inhalational Lung Injury Workshop jointly sponsored by the American Thoracic Society (ATS) and the National Institute of Health (NIH)/National Institute of Neurologic Disorders and Stroke (NINDS) Countermeasures Against Chemical Threats (CounterACT) program on May 21, 2013 in Philadelphia, PA. The CounterACT program facilitates research leading to the development of new and improved medical countermeasures for chemical threat agents. The workshop was initiated by the Terrorism and Inhalational Disasters (TID) Section of the Environmental, Occupational, and Population Health Assembly (EOPH) of the ATS...
April 18, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28417265/advancing-drug-discovery-and-development-using-molecular-imaging-addmi-an-interest-group-of-the-world-molecular-imaging-society-and-an-inaugural-session-on-positron-emission-tomography-pet
#10
Shil Patel, Karl Schmidt, Jacob Hesterman, Jack Hoppin
Multi-modality molecular imaging techniques have expanded the role of imaging biomarkers in the pharmaceutical industry and are beginning to streamline the drug discovery and development process. The World Molecular Imaging Society (WMIS) serves as a forum for discussing innovative and exploratory multi-modal, interdisciplinary molecular imaging research with a mission of bridging the gap between pathology and in vivo imaging. To formalize the role of the WMIS in pharmaceutical research efforts, members of the society have formed an interest group entitled Advancing Drug Discovery and Development using Molecular Imaging (ADDMI)...
April 17, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28414517/internet-addiction-psychological-distress-and-coping-responses-among-adolescents-and-adults
#11
Michelle L McNicol, Einar B Thorsteinsson
As Internet use grows, so do the benefits and also the risks. Thus, it is important to identify when individuals' Internet use is problematic. In the present study, 449 participants aged from 16 to 71 years of age were sourced from a wide range of English-speaking Internet forums, including social media and self-help groups. Of these, 68.9% were classified as nonproblematic users, 24.4% as problematic users, and 6.7% as addictive Internet users. High use of discussion forums, high rumination levels, and low levels of self-care were the main contributing factors to Internet addiction (IA) among adolescents...
April 17, 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28411706/report-of-the-society-for-vascular-surgery-and-the-american-venous-forum-on-the-july-20-2016-meeting-of-the-medicare-evidence-development-and-coverage-advisory-committee-panel-on-lower-extremity-chronic-venous-disease
#12
Peter Gloviczki, Michael C Dalsing, Peter Henke, Brajesh K Lal, Thomas F O'Donnell, Cynthia K Shortell, Ying Huang, Jovan Markovic, Thomas W Wakefield
On July 20, 2016, a Medicare Evidence Development and Coverage Advisory Committee panel assessed the benefits and risks of currently used lower extremity chronic venous disease (CVD) treatments and their effects on health outcome of the American adult population. The main purpose of the meeting was to advise the Centers for Medicare & Medicaid Services on coverage determination for interventions used for treatment of CVD. A systematic review of the Agency for Healthcare Research and Quality was presented, followed by lectures of invited experts and a public hearing of representatives of professional societies and the industry...
May 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28410343/patient-understanding-of-the-risks-and-benefits-of-biologic-therapies-in-inflammatory-bowel-disease-insights-from-a-large-scale-analysis-of-social-media-platforms
#13
Bibiana Martinez, Francis Dailey, Christopher V Almario, Michelle S Keller, Mansee Desai, Taylor Dupuy, Sasan Mosadeghi, Cynthia Whitman, Karen Lasch, Lyann Ursos, Brennan M R Spiegel
BACKGROUND: Few studies have examined inflammatory bowel disease (IBD) patients' knowledge and understanding of biologic therapies outside traditional surveys. Here, we used social media data to examine IBD patients' understanding of the risks and benefits associated with biologic therapies and how this affects decision-making. METHODS: We collected posts from Twitter and e-forum discussions from >3000 social media sites posted between June 27, 2012 and June 27, 2015...
April 13, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28410188/like-or-dislike-impact-of-facebook-on-ewing-sarcoma-treatment
#14
Paul Ruckenstuhl, Michael Schippinger, Paul Liebmann, Andreas Leithner, Gerwin Bernhardt
BACKGROUND: An increasing number of patients are raising their voices in online forums to exchange health-related information. Facebook is the leading social media platform with more than 1 billion international daily users recorded in the summer of 2015. Facebook has a dynamic audience and is utilized in a number of ways, discussing medical issues being one of them. Ewing sarcoma mainly affects teenagers and young adults. Additionally, many individuals within this age group are regular users of Facebook...
August 25, 2016: JMIR Cancer
https://www.readbyqxmd.com/read/28409748/a-critical-assessment-of-research-on-neurotransmitters-in-alzheimer-s-disease
#15
P Hemachandra Reddy
The purpose of this mini-forum, "Neurotransmitters and Alzheimer's Disease", is to critically assess the current status of neurotransmitters in Alzheimer's disease. Neurotransmitters are essential neurochemicals that maintain synaptic and cognitive functions in mammals, including humans, by sending signals across pre- to post-synaptic neurons. Authorities in the fields of synapses and neurotransmitters of Alzheimer's disease summarize the current status of basic biology of synapses and neurotransmitters, and also update the current status of clinical trials of neurotransmitters in Alzheimer's disease...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28407525/mind-the-gap-exploring-information-gaps-for-the-development-of-an-online-resource-hub-for-epilepsy-and-depression
#16
Rachel E Crooks, Meaghan Bell, Scott B Patten, Samuel Wiebe, Jayna Holroyd-Leduc, Andrew G Bulloch, Sophia Macrodimitris, Aaron Mackie, Khara M Sauro, Paolo Federico, Nathalie Jetté
PURPOSE: Depression is common in epilepsy, and is often under-detected and under-treated. The motivation to create a depression eHub for persons with epilepsy is to connect them to the best available online resources to effectively manage their depression. The study sought to: 1) identify facilitators and barriers to accessing resources related to management of epilepsy and/or depression and 2) discuss gaps in available resources (free and in the public domain) and 3) identify suggestions for future content...
April 10, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28407253/treatment-of-tibial-diaphyseal-fractures-following-plateless-tibial-tuberosity-advancement-to-manage-cranial-cruciate-disease
#17
R De Sousa, P Egan, K Parsons, S Butterworth, I Calvo, S Roch, A P Moores
OBJECTIVE: To report diaphyseal fractures of the proximal tibia following tibial tuberosity advancement without plate stabilisation for the management of cranial cruciate ligament rupture in dogs. METHODS: Members of the British Veterinary Orthopaedic Association's online discussion forum were invited to submit revision cases of tibial diaphyseal fracture following tibial tuberosity advancement without plate fixation. Data collected included signalment, surgical revision technique, pre- and postoperative revision radiographic findings, complications and veterinary assessment...
April 13, 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28402537/performance-assessment-and-translation-of-physiologically-based-pharmacokinetic-models-from-acslx%C3%A2-to-berkeley-madonna%C3%A2-matlab%C3%A2-and-r-language-oxytetracycline-and-gold-nanoparticles-as-case-examples
#18
Zhoumeng Lin, Majid Jaberi-Douraki, Chunla He, Shiqiang Jin, Raymond S H Yang, Jeffrey W Fisher, Jim E Riviere
Many physiologically based pharmacokinetic (PBPK) models for environmental chemicals, drugs, and nanomaterials have been developed to aid risk and safety assessments using acslXTM. However, acslXTM has been rendered sunset since November 2015. Alternative modeling tools and tutorials are needed for future PBPK applications. This forum article aimed to: (1) demonstrate the performance of four PBPK modeling software packages (acslXTM, Berkeley MadonnaTM, MATLAB®, and R language) tested using two existing models (oxytetracycline and gold nanoparticles); (2) provide a tutorial of PBPK model code conversion from acslXTM to Berkeley MadonnaTM, MATLAB®, and R language; (3) discuss the advantages and disadvantages of each software package in the implementation of PBPK models in toxicology, and (4) share our perspective about future direction in this field...
April 8, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28401812/-listen-to-your-body-participants-alternative-to-science-in-online-health-discussions
#19
Wytske Versteeg, Hedwig Te Molder, Petra Sneijder
We present a discursive psychological analysis of how the idiomatic expression "Listen to Your Body" is deployed in online forum discussions about ADHD medication and aspartame. The Listen to Your Body device allows participants to demonstrate to others that they take their health seriously and for that reason avoid scientific knowledge. They contrast Listen to Your Body with "blindly following science," presenting Listen to Your Body as the more critical and, therefore, more rational behavior. Instead of treating the idiomatic expression as "anyone's knowledge," speakers and recipients compete for the right to own it...
March 1, 2017: Health (London)
https://www.readbyqxmd.com/read/28401688/goals-of-patient-care-system-change-with-video-based-education-increases-rates-of-advance-cardiopulmonary-resuscitation-decision-making-and-discussions-in-hospitalised-rehabilitation-patients
#20
Claire Johnson, Jeffrey Chong, Anne Wilkinson, Barbara Hayes, Sonia Tait, Nicholas Waldron
BACKGROUND: Advance CPR discussions and decision-making are not routine clinical practice in the hospital setting. Frail older patients may be at risk of non-beneficial CPR. AIM: To assess the utility and safety of two interventions to increase CPR decision-making, documentation and communication for hospitalised older patients. METHODS: A pre-post study tested two interventions: i) standard ward-based education forums with CPR content; and ii) a combined, two-pronged strategy with 'Goals of Patient Care' (GoPC) system change and structured video-based workshop; against usual practice (ie no formal training)...
April 12, 2017: Internal Medicine Journal
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