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Mycobacterium intracellulare tenosynovitis

Jacob C Dutilh, Babette van Hees
A 58-year-old woman presented to an outpatient clinic with painless swellings around several joints and drenching night sweats. She had been treated with high doses of glucocorticoids for more than 20 years for dermatomyositis and the pulmonary fibrosis associated with it. On examination, she was..
October 15, 2015: New England Journal of Medicine
Ho Namkoong, Keizo Fukumoto, Igen Hongo, Naoki Hasegawa
No abstract text is available yet for this article.
June 2016: Infection
H T Chan, C C Tseng, P Y Chen, C M Chao, C C Lai
No abstract text is available yet for this article.
May 2014: QJM: Monthly Journal of the Association of Physicians
C-H Hsiao, A Cheng, Y-T Huang, C-H Liao, P-R Hsueh
PURPOSE: To investigate the clinical characteristics and pathological features of patients with mycobacterial tenosynovitis and arthritis. METHODS: All patients with tenosynovitis and arthritis caused by Mycobacterium tuberculosis (MTB) and nontuberculous mycobacteria (NTM) who were treated at a medical center in Taiwan from 2001 to 2010 were analyzed. RESULTS: Thirty-two patients with mycobacterial tenosynovitis and arthritis were identified...
April 2013: Infection
Hyun Jung Yoon, Jong Won Kwon, Young Cheol Yoon, Sang-Hee Choi
Nontuberculous mycobacterial infections can cause destructive tenosynovitis of the hand. We report on and discuss the clinical course and distinctive radiologic findings of two patients with hand tenosynovitis secondary to M. marinum and intracellulare infection, which are different from those of the nontuberculous mycobacterial infections reported in the previous literature.
November 2011: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
Carl D Moores, Ruby Grewal
We present a case of proliferative flexor tenosynovitis caused by Mycobacterium avium complex resulting in recurrent symptoms of median nerve compression. The patient was treated with radical tenosynovectomy and release of the carpal tunnel without antimicrobial therapy. She remains symptom-free and is apparently disease-free more than 2 years after surgery.
June 2011: Journal of Hand Surgery
K S Kanik, D P Greenwald
Mycobacterium avium/Mycobacterium intracellulare[cf1] complex (MAC) is a rare cause of tenosynovitis. We describe a case in which a previously healthy patient developed bilaterally symmetric synovitis and was treated with disease modifying anti rheumatic drugs (DMARDs); the synovitis progressed into a bilaterally symmetric chronic granulomatous tenosynovitis that was uncontrollable despite a synovectomy and DMARD therapy. Three years after developing symptoms, and 2 1/2 years after her diagnosis of rheumatoid arthritis, MAC was cultured from synovial fluid...
June 2000: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
Tsutomu Akahane, Yukio Nakatsuchi, Yutaka Tateiwa
We report a 65-year-old man with tenosynovitis of the wrist and finger caused by Mycobacterium intracellulare. The diagnosis was made after subsequent recurrence, when a specimen of synovial fluid was subjected to specific polymerase chain reaction and mycobacterial culture. Synovectomy and susceptibility-guided antituberculous therapy permitted complete healing of tenosynovitis.
September 2006: Diagnostic Microbiology and Infectious Disease
Masataka Noguchi, Yoshimichi Taniwaki, Toshikazu Tani
BACKGROUND: We encountered five patients with atypical Mycobacterium infections in the upper extremity, and examined their outcomes. PATIENTS AND METHODS: Two patients were male and three were female. The average patient age was 67 (range, 63-75) years. A wide synovectomy was performed to diagnose all cases followed by a therapeutic regimen of Rifampicin, Isoniazid, and Ethambutol. RESULTS: The causative atypical organism was Mycobacterium marinum in three cases and Mycobacterium intracellulare in two cases...
September 2005: Archives of Orthopaedic and Trauma Surgery
Desmond Anim-Appiah, Bartholomew Bono, Earl Fleegler, Neil Roach, Rafik Samuel, Allen R Myers
No abstract text is available yet for this article.
February 15, 2004: Arthritis and Rheumatism
Guang-Uei Hung, Joung-Liang Lan, Kuang-Tao A Yang, Wan-Yu Lin, Shyh-Jen Wang
The presented case is a 36-year-old woman with a history of systemic lupus erythematosus for 10 years. She had progressively painful swelling of the right index finger that later proved to be a rare case of tenosynovitis caused by Mycobacterium avium complex. Serial images of 3-phase bone scans, gallium scan, and magnetic resonance imaging demonstrate the area of involvement.
November 2003: Clinical Nuclear Medicine
P Lefèvre, P Gilot, H Godiscal, J Content, M Fauville-Dufaux
We report a case of recurrent granulomatous tenosynovitis with M. intracellulare in a 55-year-old HIV negative diabetic woman. Identification of the causative agent further than belonging to the M. avium-intracellulare complex is provided by specific PCR-amplification of genomic DNA and sequencing of an hypervariable region within its 16S RNA gene. Sixteen months antibiotic regimen of rifabutin and clarithromycin led to a complete resolution of the tenosynovitis.
October 2000: Diagnostic Microbiology and Infectious Disease
E Toussirot, A Chevrolet, D Wendling
Atypical mycobacteria can induce soft tissue infections such as tenosynovitis. We observed one case of finger flexor tendon tenosynovitis infected with Mycobacterium avium intracellulare and one case of knee and ankle arthritis with lateral peroneal tendon tenosynovitis due to M. chelonei. In the first patient, a tenosynovectomy only was performed leading to resolution of the infection. The second patient was immunocompromised as a result of corticosteroid therapy and the mycobacterial infection was treated with tenosynovectomy and multidrug chemotherapy...
1998: Clinical Rheumatology
D Barcat, P Mercié, J Constans, T Traissac, G Le Clouerec, J Texier-Maugein, C Conri
No abstract text is available yet for this article.
April 1998: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
M Darrow, G Foulkes, P N Richmann, C L de los Reyes, W E Floyd
Two case reports of deep hand infections with Mycobacterium avium-intracellulare are presented. Both occurred in elderly men. Aggressive surgical débridement combined with antitubercular chemotherapy resulted in an excellent outcome in both cases. Atypical mycobacterial infections should be considered in the differential diagnosis of any patient with prolonged and progressive tenosynovitis. A complete history, including temporally remote inoculation injuries or immunocompromised host status, should be elicited...
December 1995: American Journal of Orthopedics
P J Regnard, P Barry, J Isselin
We present five cases of mycobacterial tenosynovitis of the flexor tendons of the fingers. These cases were observed during the last 12 years and treated by the same surgeon. This pathology is uncommon now, but it is becoming more frequent, especially in patients with diminished immunity. The diagnosis was most commonly made after synovectomy in patients presenting with carpal tunnel syndrome associated with slightly painful swelling at the wrist. Histological and bacteriological examinations are very important and revealed tuberculosis in four of our patients and mycobacterium in one, and the treatment consists of synovectomy and appropriate antibiotics...
June 1996: Journal of Hand Surgery: Journal of the British Society for Surgery of the Hand
S H Kozin, A T Bishop
Thirty-three patients with culture-positive atypical Mycobacterium infections of the upper extremity underwent surgical debridement and antimicrobial therapy. The causative atypical organism was M. marinum in 12 cases, M. avium-intracellulare in 7, M. terrae in 4, M. chelonei in 4, M. kansasii in 3, M. fortuitum in 2, and M. ulcerans in 1. The tenosynovium was the most common location of infection (14 patients). The average follow-up period was 36 months. Duration of antimicrobial therapy averaged 10 months...
May 1994: Journal of Hand Surgery
R Patel, G D Roberts, M R Keating, C V Paya
Infections due to nontuberculous mycobacteria (NTM) in solid-organ transplant recipients are infrequent but may be a major cause of morbidity. We describe four cases of NTM infection in solid-organ transplant recipients. The manifestations included a nodule secondary to Mycobacterium kansasii infection in a heart transplant recipient, a cutaneous lesion and a pulmonary nodule secondary to M. kansasii infection in a renal transplant recipient, tenosynovitis secondary to Mycobacterium chelonae infection in a renal transplant recipient, and cutaneous lesions secondary to M...
August 1994: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
W C Hellinger, J D Smilack, J L Greider, S Alvarez, S D Trigg, N S Brewer, R S Edson
In immunocompetent patients, Mycobacterium avium/Mycobacterium intracellulare complex (MAC) has been associated with pulmonary infection in adults, cervical lymphadenitis in children, and disseminated infection in children and adults. MAC rarely has been recognized as a cause of localized soft-tissue infection in immunocompetent hosts. Six cases of granulomatous tenosynovitis due to MAC are reported; five cases occurred after local surgical procedures, trauma, or corticosteroid injection. In four cases, cure was achieved with combined medical and surgical intervention...
July 1995: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
L Demoulin, M R Lesire, L Hisette, M Leclercq, J Hamels, J Nyabenda, M Desmecht, G Viallier
The authors present one case of osteo-arthritis and tenosynovitis of the right forefinger due to Mycobacterium intracellulare, in a 61-year old woman. The treatment consists of a synovectomy of the finger's proximal interphalangeal joint and of the sheath of the flexor tendons and a drug regimen associating erythromycin and cotrimoxazole for 2 1/2 months. This therapy proves successful, as the patient is clinically cured. A literature review records 19 similar osteo-articular and peri-articular infections due to the Mycobacterium avium-intracellulare group, reported during these last 25 years...
November 1984: Pathologie-biologie
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