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Anisotrophy coefficient

H P Günbey, K Ercan, A S Fındıkoğlu, E Bilir, M Karaoglanoglu, F Komurcu, A Alhan
Epilepsy is more than a grey-matter disorder affecting large white matter connections of the brain with seizure generation and propagation. The mechanism for such changes remains unclear. The purpose of this study was to investigate the microstructural changes in the corpus callosum in temporal lobe epilepsy (TLE) patients and whether these abnormalities are related to antiepileptic drug (AED) therapy. Ten TLE patients receiving AED therapy, ten TLE patients with no therapy and ten controls were included in the study...
May 15, 2011: Neuroradiology Journal
Hyung Suk Seo, Seong-Eun Kim, John Rose, J Rock Hadley, Dennis L Parker, Eun-Kee Jeong
PURPOSE: To evaluate the feasibility of diffusion tensor imaging (DTI) for the medial and lateral rectus extraocular muscle (EOM) evaluation, to investigate the normal DTI parameters of the medial and lateral rectus EOM, and to compare with other skeletal muscle. MATERIALS AND METHODS: Seven multiple sclerosis patients and five normal subjects (M:F = 5:7, mean age = 31.6 ± 9.2) without EOM disorder were included. The orbital DTIs using 2D-ss-IMVI-DWEPI were scanned with b = 500 s/mm(2) and 12 directions...
November 2013: Journal of Magnetic Resonance Imaging: JMRI
Shanmughanathan Rajasekaran, Rishi M Kanna, Ajoy P Shetty, Venkatachalam Ilayaraja
BACKGROUND CONTEXT: Signal intensity changes observed in magnetic resonance imaging (MRI) do not reveal the actual severity of axonal damage incurred in spinal cord injuries. Diffusion tensor imaging (DTI) is an imaging technique with a potential to track individual nerve fiber tracts. PURPOSE: We explored the use of DTI in quantifying the extent of spinal cord injury and differentiated areas of injured spinal cord from regions with intact fiber tracts in a cadaveric animal model...
December 2012: Spine Journal: Official Journal of the North American Spine Society
C K Kim, S M Jang, B K Park
OBJECTIVE: The purpose of this study was to prospectively investigate differences of diffusion tensor imaging (DTI) using a different number of diffusion-encoding directions and to evaluate the feasibility of tractography in healthy prostate at 3 T. METHOD: 12 healthy volunteers underwent DTI with single-shot echo-planar imaging at 3 T using a phased-array coil. Diffusion gradients of each DTI were applied in 6 (Group 1), 15 (Group 2) and 32 (Group 3) non-collinear directions...
July 2012: British Journal of Radiology
Anthony Pease, Rex Miller
Diffusion tensor imaging (DTI) is a specialized magnetic resonance sequence to determine the direction of water molecule motion. Our hypothesis was that information derived from DTI will be significantly different in dogs with a spinal cord lesion compared with a normal dog. Eleven normal dogs and six dogs with a spinal cord lesions were imaged. DTI was performed along with standard T1- and T2-weighted sequences in transverse and sagittal planes. Fractional anisotrophy and apparent diffusion coefficient (ADC) were obtained using regions of interests centered on the cranial aspect, middle cranial, middle caudal, and caudal aspects of the spinal cord...
September 2011: Veterinary Radiology & Ultrasound
Dong Gyu Kim, Seong Ho Kim, Oh Lyong Kim, Yun Woo Cho, Su Min Son, Sung Ho Jang
There have been no studies on motor recovery in severe quadriplegic patients with traumatic brain injury (TBI) resulting from combined causes of weakness; this type of patient is often seen in rehabilitation clinics. We report on a quadriplegic patient who showed long-term motor recovery from severe weakness caused by a diffuse axonal injury (DAI) on the brainstem and a traumatic intracerebral hemorrhage (ICH) on left cerebral peduncle, as evaluated by diffuse tensor imaging (DTI) and functional MRI (fMRI)...
2009: NeuroRehabilitation
A L Tievsky, T Ptak, J Farkas
BACKGROUND AND PURPOSE: The various stages of multiple sclerosis (MS) are characterized by de- and remyelination as well as by inflammation. Diffusion MR imaging is sensitive to tissue water motion, which might correspond to these pathologic processes. Our purpose was to demonstrate differences in apparent diffusion coefficient (ADC) and diffusion tensor anisotropy in acute and chronic MS plaques and in normal-appearing brain. METHODS: Twelve MS patients underwent conventional and full-tensor diffusion MR imaging with B = 1221 s/mm2...
September 1999: AJNR. American Journal of Neuroradiology
T H Adair, M L Wells, J Hang, J P Montani
We developed a stereological method for quantitating length density (Lv; vessel length per unit reference volume) of the arterial system. Accurate estimation of Lv for a sparse system of blood vessels in a three-dimensional specimen requires information on individual vessel orientation. The method we present extracts the necessary information on vessel orientation from profile geometry. Major and minor diameters of elliptical profiles of sectioned tubular structures are used to calculate Lv. The method does not require special sectioning alignment and does not assume a prior distribution of blood vessels; however, the method does assume that arteries are cylindrical...
April 1994: American Journal of Physiology
G G Cleveland, D C Chang, C F Hazlewood, H E Rorschach
The anisotropy of the spin-diffusion coefficient Ds of water protons in skeletal muscle has been studied by pulsed NMR methods. The mid-portion of the tibialis anterior muscle of mature male rats was placed in a special sample holder by means of which the muscle fiber orientation theta relative to the diffusion direction could be varied over the range 0 degrees less than or equal to theta less than or equal to 90 degrees. The value of Ds(theta) was determined for theta = 0 degrees, 45 degrees, and 90 degrees...
September 1976: Biophysical Journal
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