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Systemic conditions and periodontal health

Ya-Qin Tan, Jing Zhang, Gang Zhou
Macroautophagy/autophagy is a conserved lysosomal degradation process essential for cell physiology and human health. By regulating apoptosis, inflammation, pathogen clearance, immune response and other cellular processes, autophagy acts as a modulator of pathogenesis and is a potential therapeutic target in diverse diseases. With regard to oral disease, autophagy can be problematic either when it is activated or impaired, because this process is involved in diverse functions, depending on the specific disease and its level of progression...
October 20, 2016: Autophagy
Pradeep Jayashantha, Newell W Johnson
Sri Lanka's Veddas/Vanniya-laeto, are a small Indigenous group today with little information on their oral health status. This report is to provide an overview on oral health status of Veddas. Oral health status was recorded by the principal investigator after obtaining consent, using World Health Organization criteria, at an initial screening point before sending the person for any necessary treatment. Total participants were 194: 78% were males>35 years. Mean decayed, missing, filled teeth was 0.9 and 3% had pockets <3...
2016: Journal of Health Care for the Poor and Underserved
Suzely As Moimaz, Najara B Rocha, Artênio Ji Garbin, Cléa As Garbin, Orlando Saliba
This study evaluated the relationships between oral conditions and oral health-related quality of life (OHRQoL), as well as related factors. A crosssectional study was performed on 119 postnatal women who had sought prenatal care during pregnancy in the public health system of São Paulo State, Brazil. The women received oral clinical exams and were interviewed using the questions on the OHIP14. A second survey with information about their socioeconomic status, pregnancy and health habits was administered. The highest OHIP14 scores were found in the area of physical pain, with an average score of 10...
September 2016: Acta Odontológica Latinoamericana: AOL
AbdelAzeem Hazem, Nabil F Bissada, Catherine Demko, Andre Paes, Lisa A Lang
PURPOSE: Obesity as a systemic risk factor associated with implant failure or other complications has not been studied. The aim of this study was to compare the frequency of implant failure and complications between obese and nonobese patients. MATERIALS AND METHODS: Charts from 220 partially edentulous patients with 321 implants were examined for demographic information, medical health history, diabetes, smoking, patient-reported height and weight, periodontal status (no, mild, moderate, or severe periodontitis), tooth number, date of the implant and prosthesis placement, and treatment notes pertinent to the complications or failure...
September 2016: International Journal of Oral & Maxillofacial Implants
Mohammad Tavakoli, Mozhgan Izadi, Jaber Yaghini, Abdolah Rastegari, Ahmad Moghareh Abed
BACKGROUND: The metabolic syndrome and periodontitis coincide with systemic inflammation and glucose tolerance disorder, which indicate the common pathophysiologic pathway of these diseases. The main goal of this study was to determine the effects of the metabolic syndrome on the periodontal indices of hemodialysis (HD) patient. MATERIALS AND METHODS: In this descriptive-analytical study, 75 persons were selected by the simple method, 50 of them were HD patients, and 25 of them were healthy people...
July 2016: Dental Research Journal
Sumit Gaur, Rupali Agnihotri
Trace mineral micronutrients are imperative for optimum host response. Populations worldwide are prone to their insufficiency owing to lifestyle changes or poor nutritional intake. Balanced levels of trace minerals like iron (Fe), zinc (Zn), selenium (Se) and copper (Cu) are essential to prevent progression of chronic conditions like periodontitis. Their excess as well as deficiency is detrimental to periodontal health. This is specifically true in relation to Fe. Furthermore, some trace elements, e.g. Se, Zn and Cu are integral components of antioxidant enzymes and prevent reactive oxygen species induced destruction of tissues...
August 31, 2016: Biological Trace Element Research
G Bergenholtz
There is a paucity of guidelines for the dental profession to assess failure of endodontic therapy. While a successful treatment can be well defined by the absence of apical periodontitis and clinical symptoms after a period of observation, failed treatment has escaped a distinct standing over the years. This article highlights aspects of significance and concludes that research ought to better explore the general health properties of persistent apical periodontitis on root-filled teeth and finally confirm the extent there is an association between apical periodontitis and adverse systemic health effects...
October 2016: Journal of Oral Rehabilitation
Frank A Scannapieco, Albert Cantos
Oral diseases, such as caries and periodontitis, not only have local effects on the dentition and on tooth-supporting tissues but also may impact a number of systemic conditions. Emerging evidence suggests that poor oral health influences the initiation and/or progression of diseases such as atherosclerosis (with sequelae including myocardial infarction and stoke), diabetes mellitus and neurodegenerative diseases (such as Alzheimer's disease, rheumatoid arthritis and others). Aspiration of oropharyngeal (including periodontal) bacteria causes pneumonia, especially in hospitalized patients and the elderly, and may influence the course of chronic obstructive pulmonary disease...
October 2016: Periodontology 2000
Paul I Eke, Liang Wei, Wenche S Borgnakke, Gina Thornton-Evans, Xingyou Zhang, Hua Lu, Lisa C McGuire, Robert J Genco
The older adult population is growing rapidly in the USA and it is expected that by 2040 the number of adults ≥ 65 years of age will have increased by about 50%. With the growth of this subpopulation, oral health status, and periodontal status in particular, becomes important in the quest to maintain an adequate quality of life. Poor oral health can have a major impact, leading to tooth loss, pain and discomfort, and may prevent older adults from chewing food properly, often leading to poor nutrition. Periodontitis is monitored in the USA at the national level as part of the Healthy People 2020 initiative...
October 2016: Periodontology 2000
Jeffrey L Ebersole, Christina L Graves, Octavio A Gonzalez, Dolph Dawson, Lorri A Morford, Pinar Emecen Huja, James K Hartsfield, Sarandeep S Huja, Subramanya Pandruvada, Shannon M Wallet
The increased prevalence and severity of periodontal disease have long been associated with aging, such that this oral condition affects the majority of the adult population over 50 years of age. Although the immune system is a critical component for maintaining health, aging can be characterized by quantitative and qualitative modifications of the immune system. This process, termed 'immunosenescence', is a progressive modification of the immune system that leads to greater susceptibility to infections, neoplasia and autoimmunity, presumably reflecting the prolonged antigenic stimulation and/or stress responses that occur across the lifespan...
October 2016: Periodontology 2000
R Kennedy, D F Lappin, P M Dixon, D Bennett, M P Riggio
REASONS FOR PERFORMING STUDY: Equine periodontitis is a common and painful condition. Despite this, the disease often goes unnoticed by owners and is thus a major welfare concern. The aetiopathogenesis of the condition remains poorly understood with few recent studies performed. The innate immune system is known to play an important role in human periodontitis, but its role in equine periodontitis has not been examined. OBJECTIVES: To quantify the mRNA levels of Toll-like receptors (TLRs) and cytokines in gingival tissue from orally healthy horses and those affected by periodontitis...
June 7, 2016: Equine Veterinary Journal
Agnieszka Kobus, Anna Kierklo, Danuta Sielicka, Sławomir Dariusz Szajda
Juvenile idiopathic arthritis (JIA) is the most common autoimmune inflammatory disease of connective tissue in children. It is characterized by progressive joint destruction which causes preserved changes in the musculoskeletal system. The literature describes fully clinical symptoms and radiological images in different subtypes of JIA. However, there is still a limited number of studies reporting on the medical condition of the oral cavity of ill children. JIA can affect hard and soft tissues of the oral cavity by: the general condition of the child's health, arthritis of the upper limbs, as the result of the pharmacotherapy, changes in secretion and composition of saliva, inflammation of the temporomandibular joint and facial deformity...
2016: Postȩpy Higieny i Medycyny Doświadczalnej
Adel S Alagl
OBJECTIVE: To evaluate the periodontal abscess as a possible oral clinical diagnostic criteria for the diagnosis of diabetes mellitus in the elderly. METHODS: In this clinical outpatient department, cross-sectional study of 84 months, 143 212 subjects between the ages of 40 and 84 years were screened for the presence of periodontal abscess. Relevant medical and dental histories were recorded using a questionnaire. The subjects who fulfilled the inclusion criteria of undiagnosed diabetes mellitus, presence of periodontal abscess, and absence of other systemic disease were referred for laboratory diagnosis of diabetes mellitus (HbA1c)...
May 8, 2016: Journal of Investigative and Clinical Dentistry
Butchibabu Kalakonda, Pradeep Koppolu, Kusai Baroudi, Ashank Mishra
Periodontal diseases, considered as inflammatory diseases have proved to have a spectrum of systemic implications. Earliest research has associated periodontal disease with common systemic aliments such as hypertension, diabetes, osteoporosis, rheumatoid arthritis to name a few. The evolution of advanced diagnostic aids let researchers make vast inroads in linking periodontal diseases to systemic diseases like Alzheimer's disease (AD) and even Schizophrenia. Our aim was to review and critically evaluate comprehensive literature and provide knowledge to medical practitioners on these associations so as to pave way for closer interactions between medical and dental practitioners in implementing better health care...
April 2016: International Journal of Health Sciences
Gregory K An, Douglas E Morse, Marc Kunin, Robert S Goldberger, Walter J Psoter
INTRODUCTION: Numerous studies have demonstrated an association between oral health status and systemic diseases. However, reports examining apical periodontitis (AP) and cardiovascular disease (CVD) are few. This study investigates whether an association exists between AP and CVD. METHODS: The present study was a pair-matched, cross-sectional design that used medical and dental chart review. The AP group (n = 182) was defined as subjects with radiographic AP, and the non-AP group (n = 182) was defined as subjects without any radiographic AP...
June 2016: Journal of Endodontics
N S Venkatesh Babu, Purna B Patel
BACKGROUND: Thyroid dysfunction is the second most common disorder of the endocrine system that can affect any system of the body. The oral cavity can be adversely affected by either an excess or deficiency of these hormones. AIM OF THE STUDY: To assess and compare the oral health status of children suffering from thyroid disorders and healthy children. MATERIALS AND METHODS: A total of 200 children aged between 2 years and 16 years were allocated into two groups...
April 2016: Journal of the Indian Society of Pedodontics and Preventive Dentistry
Ana Paula Castilho Garcia Seraphim, Fernando Yamamoto Chiba, Renato Felipe Pereira, Maria Sara de Lima Coutinho Mattera, Suzely Adas Saliba Moimaz, Doris Hissako Sumida
Pregnancy is a period involving important metabolic changes that enable the maintenance of the mother's health and development of the fetus. This study aimed to assess the relationship among periodontal disease, insulin resistance, salivary cortisol concentration and level of perceived stress in pregnant women. This was a cross-sectional study. The sample comprised 96 pregnant women between the fifth and seventh month of pregnancy registered at the Basic Health Units of the Unified Health System (SUS). The periodontal condition was assessed after obtainment free and informed consent from the participants...
March 2016: Brazilian Dental Journal
Mohammed Jafer
AIM: Periodontal diseases are associated with systemic health and health behaviors; the purpose of this study was to investigate periodontal health status and its association with systemic health and health behaviors in the elderly. MATERIALS AND METHODS: Data was collected from 300 random Case Western Reserve University (CWRU) dental school patient charts, aged 65 or higher. A modified WHO form was used to collect the date on: periodontal conditions using the community periodontal index (CPI), demographics, systemic health and certain health behaviors...
December 2015: Journal of Contemporary Dental Practice
Debra M Ferraiolo
DATA SOURCES: Cochrane Library, Ovid, Medline, Embase and LILACS were searched using no language restrictions and included information up to July 2014. Bibliographic references of included articles and related review articles were hand searched. On-line hand searching of recent issues of key periodontal journals was performed (Journal of Clinical Periodontology, Journal of Dental Research, Journal of Periodontal Research, Journal of Periodontology, Oral Health and Preventive Dentistry)...
March 2016: Evidence-based Dentistry
Irlan Almeida Freires, Pedro Luiz Rosalen
PURPOSES: Despite the high number of studies on the biological effects of natural products (NP) and molecules isolated therefrom, only a small part of them reach the clinical phase and become commercially available. In this perspective we make an analysis on how plant research has impacted oral health care over the last 15 years. METHODS: Sixteen major clinical trial registry databases across the globe were searched for completed randomized clinical trials of herbal/natural product interventions (RCTHI) in theperiod 2000-2015...
June 2016: Pharmaceutical Research
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