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Systemic conditions and periodontal health

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https://www.readbyqxmd.com/read/28326737/-research-progress-on-a-nanodrug-delivery-system-for-prevention-and-control-of-dental-caries-and-periodontal-diseases
#1
Jiang Yaling, Feng Mingye, Cheng Lei
Dental caries and periodontal diseases are common chronic infectious diseases that cause serious damage to oral health. Bacteria is the primary factor leading to such conditions. As a dental plaque control method, chemotherapeutic agents face serious challenges in dental care because of the specific physiological and anatomical characteristics of the oral cavity. Nanodrug delivery system is a series of new drug delivery systems at nanoscale, and it can target cells, promote sustainedrelease effects, and enhance biodegradation...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28317488/association-between-periodontal-health-status-and-cognitive-abilities-the-role-of-cytokine-profile-and-systemic-inflammation
#2
Marta Sochocka, Maciej Sobczyński, Aleksandra Sender-Janeczek, Katarzyna Zwolińska, Olga Błachowicz, Tomasz Tomczyk, Marek Ziętek, Jerzy Leszek
BACKGROUND: Contemporary neurobiology, periodontal medicine, and immunology are now focusing on the relationship between chronic periodontitis and systemic diseases, that also include Alzheimer's disease (AD). However a causative relationship between dementia and periodontitis has yet to be confirmed. OBJECTIVE: The aim of the study was to determine whether periodontal health status and cognitive abilities are correlated with the relative changes in systemic measures of pro- and anti-inflammatory cytokines as a reflection of systemic inflammation...
March 16, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28277873/periodontal-disease-and-women-s-health
#3
Maria Luisa Martelli, Maria Luisa Brandi, Marialaura Martelli, Piero Nobili, Enzo Medico, Francesco Martelli
BACKGROUND: Periodontal disease (PD) is a multifactorial inflammatory condition in which inappropriate interaction between the host immune response and specific groups of bacterial pathogens leads to destruction of connective and bone tissues supporting the tooth. Dissemination of pathogens, toxins, and immune complexes from and to periodontal lesions is at the basis of the increasingly recognized association between PD and various systemic diseases (SDs). Considering the growing attention of the medical community to "gender medicine", this review focuses on the association between PD and six systemic conditions heavily impacting women's health, with the aim of providing evidence in support of a joint effort between physicians and dentists to improve clinical management of these conditions...
March 24, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28148273/prevalence-of-candida-albicans-and-non-albicans-on-the-tongue-dorsa-of-elderly-people-living-in-a-post-disaster-area-a-cross-sectional-survey
#4
Toshiro Sato, Mitsuo Kishi, Miki Suda, Kiyomi Sakata, Haruki Shimoda, Hiroyuki Miura, Akira Ogawa, Seiichiro Kobayashi
BACKGROUND: Candida species are normal commensal organisms of the mouth. However, they can cause oral mucosal and severe systemic infections in persons with reduced immune function, which is common in the very elderly. In post-disaster areas, the number of elderly residents rapidly increases due to the outflow of younger generations. Hence, we examined the prevalence of Candida albicans and non-albicans in association with oral and systemic conditions, life style, medications, and living conditions...
February 1, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28050500/influence-of-hypertension-on-ph-of-saliva-and-flow-rate-in-elder-adults-correlating-with-oral-health-status
#5
Vijayalaxmi Nimma, Harshavardhan Talla, Manasa Poosa, Madhulatha Gopaladas, Deepika Meesala, L Jayanth
INTRODUCTION: One of the most prevalent systemic conditions seen in the elderly individuals is hypertension, but very sparse knowledge regarding the influence of hypertension on oral health in known. AIM: Therefore, this study was carried out to evaluate the relationship between hypertension and salivary pH, flow rate and its effect on oral health status. MATERIALS AND METHODS: The study included 40 elderly individuals above 60 years of age, of which 20 individuals (control group) were normotensive without using any medication and 20 individuals (study group) were hypertensive using anti-hypertensive medication...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28032903/serum-lipids-modify-periodontal-infection-interleukin-6-association
#6
Anniina Haro, Tuomas Saxlin, Anna Liisa Suominen, Antti Jula, Matti Knuuttila, Pekka Ylöstalo
AIM: The aim of this study was to investigate whether the systemic response against a local inflammatory process in periodontium is dependent on the individual's serum lipid composition. MATERIAL AND METHODS: This study was based on a subpopulation of the Health 2000 Survey that included 878 subjects who were aged between 45 and 64 years, dentate, non-diabetic and non-rheumatic. The inflammatory condition of periodontium was measured by means of the number of teeth with deepened (4 mm or deeper) periodontal pockets...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27926431/the-oral-microbiome-in-health-and-its-implication-in-oral-and-systemic-diseases
#7
B Sampaio-Maia, I M Caldas, M L Pereira, D Pérez-Mongiovi, R Araujo
The oral microbiome can alter the balance between health and disease, locally and systemically. Within the oral cavity, bacteria, archaea, fungi, protozoa, and viruses may all be found, each having a particular role, but strongly interacting with each other and with the host, in sickness or in health. A description on how colonization occurs and how the oral microbiome dynamically evolves throughout the host's life is given. In this chapter the authors also address oral and nonoral conditions in which oral microorganisms may play a role in the etiology and progression, presenting the up-to-date knowledge on oral dysbiosis as well as the known underlying pathophysiologic mechanisms involving oral microorganisms in each condition...
2016: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/27861844/periodontal-disease-and-risk-of-non-hodgkin-lymphoma-in-the-health-professionals-follow-up-study
#8
Kimberly A Bertrand, Janki Shingala, Andrew Evens, Brenda M Birmann, Edward Giovannucci, Dominique S Michaud
Periodontal disease is a chronic inflammatory condition that has been associated with chronic diseases, including cancer. In an earlier prospective cohort analysis within the Health Professionals Follow-Up Study (HPFS), we observed a 31% higher risk of non-Hodgkin lymphoma (NHL) among participants with severe periodontal disease at baseline. Here, we extend the study with an additional 8 years of follow-up, and conduct analyses with updated periodontal disease status and NHL subtypes. The HPFS is an ongoing prospective cohort study of 51,529 men in the USA Between baseline in 1986 and 2012, 875 cases of NHL were diagnosed, including 290 chronic lymphocytic leukemia/small lymphocytic lymphomas (CLL/SLL), 85 diffuse large B-cell lymphomas and 91 follicular lymphomas...
March 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27861820/periodontal-disease-and-the-metabolic-syndrome
#9
REVIEW
Ira B Lamster, Michael Pagan
The metabolic syndrome (MetS) is a spectrum of conditions that increase the risk of cardiovascular disease and diabetes mellitus. The components of MetS include dysglycemia, visceral obesity, atherogenic dyslipidemia (elevated triglycerides and low levels of high-density lipoprotein) and hypertension. An association of periodontal disease and MetS has been suggested. This association is believed to be the result of systemic oxidative stress and an exuberant inflammatory response. When examined individually, the components of the MetS that are most closely related to the risk of periodontitis are dysglycemia and obesity, with lesser contributions by atherogenic dyslipidemia and hypertension...
November 9, 2016: International Dental Journal
https://www.readbyqxmd.com/read/27764582/autophagy-and-its-implication-in-human-oral-diseases
#10
Ya-Qin Tan, Jing Zhang, Gang Zhou
Macroautophagy/autophagy is a conserved lysosomal degradation process essential for cell physiology and human health. By regulating apoptosis, inflammation, pathogen clearance, immune response and other cellular processes, autophagy acts as a modulator of pathogenesis and is a potential therapeutic target in diverse diseases. With regard to oral disease, autophagy can be problematic either when it is activated or impaired, because this process is involved in diverse functions, depending on the specific disease and its level of progression...
February 2017: Autophagy
https://www.readbyqxmd.com/read/27763437/oral-health-status-of-the-veddas-sri-lankan-indigenous-people
#11
Pradeep Jayashantha, Newell W Johnson
Sri Lanka's Veddas/Vanniya-laeto, are a small Indigenous group today with little information on their oral health status. This report is to provide an overview on oral health status of Veddas. Oral health status was recorded by the principal investigator after obtaining consent, using World Health Organization criteria, at an initial screening point before sending the person for any necessary treatment. Total participants were 194: 78% were males>35 years. Mean decayed, missing, filled teeth was 0.9 and 3% had pockets <3...
2016: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/27731489/influence-of-oral-health-on-quality-of-life-in-pregnant-women
#12
Suzely As Moimaz, Najara B Rocha, Artênio Ji Garbin, Cléa As Garbin, Orlando Saliba
This study evaluated the relationships between oral conditions and oral health-related quality of life (OHRQoL), as well as related factors. A crosssectional study was performed on 119 postnatal women who had sought prenatal care during pregnancy in the public health system of São Paulo State, Brazil. The women received oral clinical exams and were interviewed using the questions on the OHIP14. A second survey with information about their socioeconomic status, pregnancy and health habits was administered. The highest OHIP14 scores were found in the area of physical pain, with an average score of 10...
September 2016: Acta Odontológica Latinoamericana: AOL
https://www.readbyqxmd.com/read/27632265/comparison-of-preprosthetic-implant-complications-and-failures-between-obese-and-nonobese-patients
#13
AbdelAzeem Hazem, Nabil F Bissada, Catherine Demko, Andre Paes, Lisa A Lang
PURPOSE: Obesity as a systemic risk factor associated with implant failure or other complications has not been studied. The aim of this study was to compare the frequency of implant failure and complications between obese and nonobese patients. MATERIALS AND METHODS: Charts from 220 partially edentulous patients with 321 implants were examined for demographic information, medical health history, diabetes, smoking, patient-reported height and weight, periodontal status (no, mild, moderate, or severe periodontitis), tooth number, date of the implant and prosthesis placement, and treatment notes pertinent to the complications or failure...
September 2016: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/27605991/a-survey-on-the-effects-of-metabolic-syndrome-on-the-periodontal-indices-of-hemodialysis-patients
#14
Mohammad Tavakoli, Mozhgan Izadi, Jaber Yaghini, Abdolah Rastegari, Ahmad Moghareh Abed
BACKGROUND: The metabolic syndrome and periodontitis coincide with systemic inflammation and glucose tolerance disorder, which indicate the common pathophysiologic pathway of these diseases. The main goal of this study was to determine the effects of the metabolic syndrome on the periodontal indices of hemodialysis (HD) patient. MATERIALS AND METHODS: In this descriptive-analytical study, 75 persons were selected by the simple method, 50 of them were HD patients, and 25 of them were healthy people...
July 2016: Dental Research Journal
https://www.readbyqxmd.com/read/27580897/trace-mineral-micronutrients-and-chronic-periodontitis-a-review
#15
REVIEW
Sumit Gaur, Rupali Agnihotri
Trace mineral micronutrients are imperative for optimum host response. Populations worldwide are prone to their insufficiency owing to lifestyle changes or poor nutritional intake. Balanced levels of trace minerals like iron (Fe), zinc (Zn), selenium (Se) and copper (Cu) are essential to prevent progression of chronic conditions like periodontitis. Their excess as well as deficiency is detrimental to periodontal health. This is specifically true in relation to Fe. Furthermore, some trace elements, e.g. Se, Zn and Cu are integral components of antioxidant enzymes and prevent reactive oxygen species induced destruction of tissues...
August 31, 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/27519460/assessment-of-treatment-failure-in-endodontic-therapy
#16
REVIEW
G Bergenholtz
There is a paucity of guidelines for the dental profession to assess failure of endodontic therapy. While a successful treatment can be well defined by the absence of apical periodontitis and clinical symptoms after a period of observation, failed treatment has escaped a distinct standing over the years. This article highlights aspects of significance and concludes that research ought to better explore the general health properties of persistent apical periodontitis on root-filled teeth and finally confirm the extent there is an association between apical periodontitis and adverse systemic health effects...
October 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/27501498/oral-inflammation-and-infection-and-chronic-medical-diseases-implications-for-the-elderly
#17
REVIEW
Frank A Scannapieco, Albert Cantos
Oral diseases, such as caries and periodontitis, not only have local effects on the dentition and on tooth-supporting tissues but also may impact a number of systemic conditions. Emerging evidence suggests that poor oral health influences the initiation and/or progression of diseases such as atherosclerosis (with sequelae including myocardial infarction and stoke), diabetes mellitus and neurodegenerative diseases (such as Alzheimer's disease, rheumatoid arthritis and others). Aspiration of oropharyngeal (including periodontal) bacteria causes pneumonia, especially in hospitalized patients and the elderly, and may influence the course of chronic obstructive pulmonary disease...
October 2016: Periodontology 2000
https://www.readbyqxmd.com/read/27501492/periodontitis-prevalence-in-adults-%C3%A2-%C3%A2-65%C3%A2-years-of-age-in-the-usa
#18
REVIEW
Paul I Eke, Liang Wei, Wenche S Borgnakke, Gina Thornton-Evans, Xingyou Zhang, Hua Lu, Lisa C McGuire, Robert J Genco
The older adult population is growing rapidly in the USA and it is expected that by 2040 the number of adults ≥ 65 years of age will have increased by about 50%. With the growth of this subpopulation, oral health status, and periodontal status in particular, becomes important in the quest to maintain an adequate quality of life. Poor oral health can have a major impact, leading to tooth loss, pain and discomfort, and may prevent older adults from chewing food properly, often leading to poor nutrition. Periodontitis is monitored in the USA at the national level as part of the Healthy People 2020 initiative...
2016: Periodontology 2000
https://www.readbyqxmd.com/read/27501491/aging-inflammation-immunity-and-periodontal-disease
#19
REVIEW
Jeffrey L Ebersole, Christina L Graves, Octavio A Gonzalez, Dolph Dawson, Lorri A Morford, Pinar Emecen Huja, James K Hartsfield, Sarandeep S Huja, Subramanya Pandruvada, Shannon M Wallet
The increased prevalence and severity of periodontal disease have long been associated with aging, such that this oral condition affects the majority of the adult population over 50 years of age. Although the immune system is a critical component for maintaining health, aging can be characterized by quantitative and qualitative modifications of the immune system. This process, termed 'immunosenescence', is a progressive modification of the immune system that leads to greater susceptibility to infections, neoplasia and autoimmunity, presumably reflecting the prolonged antigenic stimulation and/or stress responses that occur across the lifespan...
2016: Periodontology 2000
https://www.readbyqxmd.com/read/27270960/gingival-toll-like-receptor-and-cytokine-mrna-levels-in-equine-periodontitis-and-oral-health
#20
R Kennedy, D F Lappin, P M Dixon, D Bennett, M P Riggio
REASONS FOR PERFORMING STUDY: Equine periodontitis is a common and painful condition. Despite this, the disease often goes unnoticed by owners and is thus a major welfare concern. The aetiopathogenesis of the condition remains poorly understood with few recent studies performed. The innate immune system is known to play an important role in human periodontitis, but its role in equine periodontitis has not been examined. OBJECTIVES: To quantify the mRNA levels of Toll-like receptors (TLRs) and cytokines in gingival tissue from orally healthy horses and those affected by periodontitis...
June 7, 2016: Equine Veterinary Journal
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