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Systemic conditions and periodontal health

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https://www.readbyqxmd.com/read/28637979/the-oral-microbiome-and-human-health
#1
Yoshihisa Yamashita, Toru Takeshita
In this brief review, we discuss our previous research on the relationship between the bacterial composition of salivary microbiota and periodontal disease. Analysis using a terminal restriction fragment length polymorphism method and an international comparison suggest that the predominance of the genera Prevotella and Veillonella in the salivary microbiota is attributable to periodontal disease conditions, and that the predominance of the genus Neisseria indicates healthy periodontal conditions. Furthermore, we recently used next-generation sequencing technology to perform a detailed large-scale analysis of the salivary microbiota...
2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28632755/potassium-is-a-key-signal-in-host-microbiome-dysbiosis-in-periodontitis
#2
Susan Yost, Ana E Duran-Pinedo, Keerthana Krishnan, Jorge Frias-Lopez
Dysbiosis, or the imbalance in the structural and/or functional properties of the microbiome, is at the origin of important infectious inflammatory diseases such as inflammatory bowel disease (IBD) and periodontal disease. Periodontitis is a polymicrobial inflammatory disease that affects a large proportion of the world's population and has been associated with a wide variety of systemic health conditions, such as diabetes, cardiovascular and respiratory diseases. Dysbiosis has been identified as a key element in the development of the disease...
June 20, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28605006/treating-periodontal-disease-for-preventing-adverse-birth-outcomes-in-pregnant-women
#3
REVIEW
Zipporah Iheozor-Ejiofor, Philippa Middleton, Marco Esposito, Anne-Marie Glenny
BACKGROUND: Periodontal disease has been linked with a number of conditions, such as cardiovascular disease, stroke, diabetes and adverse pregnancy outcomes, all likely through systemic inflammatory pathways. It is common in women of reproductive age and gum conditions tend to worsen during pregnancy. Some evidence from observational studies suggests that periodontal intervention may reduce adverse pregnancy outcomes. There is need for a comprehensive Cochrane review of randomised trials to assess the effect of periodontal treatment on perinatal and maternal health...
June 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28473854/medical-and-periodontal-clinical-parameters-in-patients-at-different-levels-of-chronic-renal-failure
#4
Caroline Perozini, Gilson Fernandes Ruivo, Lucilene Hernandes Ricardo, Larissa Avance Pavesi, Yeon Jung Kim, Debora Pallos
Aim. To assess the clinical periodontal and medical parameters in patients with chronic renal failure (CRF) at different levels of renal disease. Background. CRF is a progressive and irreversible loss of renal function associated with a decline in the glomerular filtration rate. Periodontal disease is a destructive inflammatory disease affecting periodontal tissues that shows high prevalence in patients with CRF. Materials and Methods. 102 CRF patients were included and divided into an early stage group (EG), predialysis group (PDG), and hemodialysis group (HDG)...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28453484/can-better-management-of-periodontal-disease-delay-the-onset-and-progression-of-alzheimer-s-disease
#5
Alice Harding, Sarita Robinson, StJohn Crean, Sim K Singhrao
A risk factor relationship exists between periodontal disease and Alzheimer's disease (AD) via tooth loss, and improved memory following dental intervention. This links the microbial contribution from indigenous oral periodontal pathogens to the manifestation of chronic conditions, such as AD. Here, we use Porphyromonas gingivalis infection to illustrate its effect on mental health. P. gingivalis infection, in its primary sub-gingival niche, can cause polymicrobial synergy and dysbiosis. Dysbiosis describes the residency of select commensals from the oral cavity following co-aggregation around the dominant keystone pathogen, such as P...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28429488/interdisciplinary-periodontics-the-multidisciplinary-approach-to-the-planning-and-treatment-of-complex-cases
#6
REVIEW
Karl M Lyons, Ivan Darby
Periodontics cannot be practiced in isolation as frequently many patients have multiple dental needs or medical health issues requiring management. In addition, pathology may manifest in the periodontal tissues, and the onset and progression of periodontitis can be affected by systemic conditions, such as diabetes, and vice versa. The focus of this volume of Periodontology 2000 is interdisciplinary periodontics, and the articles included discuss the interactions and the interrelationshipbetween periodontal tissues/periodontal diseases and endodontics, fixed prosthodontics, implant dentistry, esthetics, gerodontology, radiology, orthodontics, pediatric dentistry, oral and maxillofacial surgery, oral pathology, special needs dentistry and general medicine...
June 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28429485/the-place-of-periodontal-examination-and-referral-in-general-medicine
#7
REVIEW
Samuel Chan, Graham M Pasternak, Malcolm J West
In many countries, dental services, unlike other health-care services, are not covered by the principle of universal access. It is only in the last couple of decades that there has been a greater interaction between medicine and dentistry. Various health-care systems worldwide may provide public dental services to the young and the disadvantaged, but few provide access to all. Public policy does not appear to appreciate the vast economic, health and social implications of poor oral health on the overall health of an individual...
June 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28429479/dental-geriatrics-and-periodontitis
#8
REVIEW
Gösta Rutger Persson
The present literature review is focused on two main areas: (i) periodontal conditions in older individuals; and (ii) the scientific data available on periodontal treatment outcomes in individuals ≥ 75 years of age. The population of older people is increasing but the data on periodontal therapies and their efficacy in this population are limited and need to be carefully reviewed. Although life expectancy has increased, this does not mean that older people are medically healthy. Several chronic systemic diseases are associated with periodontitis, and the prevalence of most chronic diseases increases with age...
June 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28393367/increasing-popularity-of-waterpipe-tobacco-smoking-and-electronic-cigarette-use-implications-for-oral-healthcare
#9
REVIEW
C P Ramôa, T Eissenberg, S E Sahingur
Cigarette smoking increases the risk of developing several systemic conditions including cancer, cardiovascular and pulmonary diseases. Cigarette smoking is also detrimental to oral health as it increases the incidence and severity of oral cancer, periodontal diseases and peri-implantitis, as well as impacting negatively on the dental patients' response to therapy. Therefore, consideration of smoking behavior and recommendation of smoking cessation are important parts of dental treatment planning. However, cigarettes are no longer the most popular form of tobacco use among adolescents in the United States and globally...
April 10, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28349910/good-bugs-vs-bad-bugs-evaluation-of-inhibitory-effect-of-selected-probiotics-against-enterococcus-faecalis
#10
Aarti A Bohora, Sharad R Kokate
INTRODUCTION: The main goal of endodontics is the prevention of apical periodontitis. This is due to the presence of persistent pathogenic microorganisms, such as Enterococcus faecalis, and its ability to directly cause acute and chronic inflammation in the periapical tissues. Lactobacillus has been shown to promote health in the intestines as well as to inhibit the growth of certain problematic oral bacteria. This study explores shifting the established paradigm of endodontic treatment, which has focused on eliminating all bacteria from the canal system and on elimination of the problematic bacteria through introducing probiotics...
April 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28326737/-research-progress-on-a-nanodrug-delivery-system-for-prevention-and-control-of-dental-caries-and-periodontal-diseases
#11
REVIEW
Jiang Yaling, Feng Mingye, Cheng Lei
Dental caries and periodontal diseases are common chronic infectious diseases that cause serious damage to oral health. Bacteria is the primary factor leading to such conditions. As a dental plaque control method, chemotherapeutic agents face serious challenges in dental care because of the specific physiological and anatomical characteristics of the oral cavity. Nanodrug delivery system is a series of new drug delivery systems at nanoscale, and it can target cells, promote sustainedrelease effects, and enhance biodegradation...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28317488/association-between-periodontal-health-status-and-cognitive-abilities-the-role-of-cytokine-profile-and-systemic-inflammation
#12
Marta Sochocka, Maciej Sobczyński, Aleksandra Sender-Janeczek, Katarzyna Zwolińska, Olga Błachowicz, Tomasz Tomczyk, Marek Ziętek, Jerzy Leszek
BACKGROUND: Contemporary neurobiology, periodontal medicine, and immunology are now focusing on the relationship between chronic periodontitis and systemic diseases, that also include Alzheimer's disease (AD). However a causative relationship between dementia and periodontitis has yet to be confirmed. OBJECTIVE: The aim of the study was to determine whether periodontal health status and cognitive abilities are correlated with the relative changes in systemic measures of pro- and anti-inflammatory cytokines as a reflection of systemic inflammation...
March 16, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28277873/periodontal-disease-and-women-s-health
#13
Maria Luisa Martelli, Maria Luisa Brandi, Marialaura Martelli, Piero Nobili, Enzo Medico, Francesco Martelli
BACKGROUND: Periodontal disease (PD) is a multifactorial inflammatory condition in which inappropriate interaction between the host immune response and specific groups of bacterial pathogens leads to destruction of connective and bone tissues supporting the tooth. Dissemination of pathogens, toxins, and immune complexes from and to periodontal lesions is at the basis of the increasingly recognized association between PD and various systemic diseases (SDs). Considering the growing attention of the medical community to "gender medicine", this review focuses on the association between PD and six systemic conditions heavily impacting women's health, with the aim of providing evidence in support of a joint effort between physicians and dentists to improve clinical management of these conditions...
June 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28148273/prevalence-of-candida-albicans-and-non-albicans-on-the-tongue-dorsa-of-elderly-people-living-in-a-post-disaster-area-a-cross-sectional-survey
#14
Toshiro Sato, Mitsuo Kishi, Miki Suda, Kiyomi Sakata, Haruki Shimoda, Hiroyuki Miura, Akira Ogawa, Seiichiro Kobayashi
BACKGROUND: Candida species are normal commensal organisms of the mouth. However, they can cause oral mucosal and severe systemic infections in persons with reduced immune function, which is common in the very elderly. In post-disaster areas, the number of elderly residents rapidly increases due to the outflow of younger generations. Hence, we examined the prevalence of Candida albicans and non-albicans in association with oral and systemic conditions, life style, medications, and living conditions...
February 1, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28050500/influence-of-hypertension-on-ph-of-saliva-and-flow-rate-in-elder-adults-correlating-with-oral-health-status
#15
Vijayalaxmi Nimma, Harshavardhan Talla, Manasa Poosa, Madhulatha Gopaladas, Deepika Meesala, L Jayanth
INTRODUCTION: One of the most prevalent systemic conditions seen in the elderly individuals is hypertension, but very sparse knowledge regarding the influence of hypertension on oral health in known. AIM: Therefore, this study was carried out to evaluate the relationship between hypertension and salivary pH, flow rate and its effect on oral health status. MATERIALS AND METHODS: The study included 40 elderly individuals above 60 years of age, of which 20 individuals (control group) were normotensive without using any medication and 20 individuals (study group) were hypertensive using anti-hypertensive medication...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28032903/serum-lipids-modify-periodontal-infection-interleukin-6-association
#16
Anniina Haro, Tuomas Saxlin, Anna Liisa Suominen, Antti Jula, Matti Knuuttila, Pekka Ylöstalo
AIM: The aim of this study was to investigate whether the systemic response against a local inflammatory process in periodontium is dependent on the individual's serum lipid composition. MATERIAL AND METHODS: This study was based on a subpopulation of the Health 2000 Survey that included 878 subjects who were aged between 45 and 64 years, dentate, non-diabetic and non-rheumatic. The inflammatory condition of periodontium was measured by means of the number of teeth with deepened (4 mm or deeper) periodontal pockets...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27926431/the-oral-microbiome-in-health-and-its-implication-in-oral-and-systemic-diseases
#17
B Sampaio-Maia, I M Caldas, M L Pereira, D Pérez-Mongiovi, R Araujo
The oral microbiome can alter the balance between health and disease, locally and systemically. Within the oral cavity, bacteria, archaea, fungi, protozoa, and viruses may all be found, each having a particular role, but strongly interacting with each other and with the host, in sickness or in health. A description on how colonization occurs and how the oral microbiome dynamically evolves throughout the host's life is given. In this chapter the authors also address oral and nonoral conditions in which oral microorganisms may play a role in the etiology and progression, presenting the up-to-date knowledge on oral dysbiosis as well as the known underlying pathophysiologic mechanisms involving oral microorganisms in each condition...
2016: Advances in Applied Microbiology
https://www.readbyqxmd.com/read/27861844/periodontal-disease-and-risk-of-non-hodgkin-lymphoma-in-the-health-professionals-follow-up-study
#18
Kimberly A Bertrand, Janki Shingala, Andrew Evens, Brenda M Birmann, Edward Giovannucci, Dominique S Michaud
Periodontal disease is a chronic inflammatory condition that has been associated with chronic diseases, including cancer. In an earlier prospective cohort analysis within the Health Professionals Follow-Up Study (HPFS), we observed a 31% higher risk of non-Hodgkin lymphoma (NHL) among participants with severe periodontal disease at baseline. Here, we extend the study with an additional 8 years of follow-up, and conduct analyses with updated periodontal disease status and NHL subtypes. The HPFS is an ongoing prospective cohort study of 51,529 men in the USA Between baseline in 1986 and 2012, 875 cases of NHL were diagnosed, including 290 chronic lymphocytic leukemia/small lymphocytic lymphomas (CLL/SLL), 85 diffuse large B-cell lymphomas and 91 follicular lymphomas...
March 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27861820/periodontal-disease-and-the-metabolic-syndrome
#19
REVIEW
Ira B Lamster, Michael Pagan
The metabolic syndrome (MetS) is a spectrum of conditions that increase the risk of cardiovascular disease and diabetes mellitus. The components of MetS include dysglycemia, visceral obesity, atherogenic dyslipidemia (elevated triglycerides and low levels of high-density lipoprotein) and hypertension. An association of periodontal disease and MetS has been suggested. This association is believed to be the result of systemic oxidative stress and an exuberant inflammatory response. When examined individually, the components of the MetS that are most closely related to the risk of periodontitis are dysglycemia and obesity, with lesser contributions by atherogenic dyslipidemia and hypertension...
November 9, 2016: International Dental Journal
https://www.readbyqxmd.com/read/27764582/autophagy-and-its-implication-in-human-oral-diseases
#20
Ya-Qin Tan, Jing Zhang, Gang Zhou
Macroautophagy/autophagy is a conserved lysosomal degradation process essential for cell physiology and human health. By regulating apoptosis, inflammation, pathogen clearance, immune response and other cellular processes, autophagy acts as a modulator of pathogenesis and is a potential therapeutic target in diverse diseases. With regard to oral disease, autophagy can be problematic either when it is activated or impaired, because this process is involved in diverse functions, depending on the specific disease and its level of progression...
February 2017: Autophagy
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