keyword
MENU ▼
Read by QxMD icon Read
search

Femoral head avascular necrosis

keyword
https://www.readbyqxmd.com/read/29286832/avascular-necrosis-of-the-femoral-head
#1
Roberto Seijas, Andrea Sallent, Eila Rivera, Oscar Ares
About 250000 patients are operated on annually for hip arthroplasty in the USA alone. Of this number, about 10% the cause of their osteoarthritis is the avascular necrosis of the femoral head. But the causes of necrosis are multiple and many of them are still unknown. That is why small advances in etiopathogenesis, diagnosis and treatment of different causes are very important in order to reduce the number of affected patients. It may seem that small changes, studies focused on the details of different diseases do not bring great changes to science, but it is these small changes that end up adding great evolutions in our knowledge...
December 29, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29286130/salidroside-inhibits-steroid-induced-avascular-necrosis-of-the-femoral-head-via-the-pi3k-akt-signaling-pathway-in%C3%A2-vitro-and-in%C3%A2-vivo-studies
#2
Xing-He Xue, Zhen-Hua Feng, Zhen-Xing Li, Xiao-Yun Pan
Dexamethasone (Dex) and other glucocorticoids are widely used to treat serious infections and immunological diseases, however they may cause steroid‑induced avascular necrosis of the femoral head (SANFH). Salidroside (Sal) has demonstrated an anti‑apoptotic effect on neurocytes by activating the phosphoinositide 3‑kinase (PI3K)/protein kinase B (Akt) signaling pathway. In the present study, primary osteoblasts were used in vitro and in rats in vivo to determine the anti-apoptotic effect of Sal on SANFH...
December 27, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29261271/managing-dislocations-of-the-hip-knee-and-ankle-in-the-emergency-department-digest
#3
Caylyne Arnold, Zane Fayos, David Bruner, Dylan Arnold, Nachi Gupta, Jeffrey Nusbaum
Dislocation of the major joints of the lower extremities--hip, knee, and ankle--can occur due to motor-vehicle crashes, falls, and sports injuries. Hip dislocations are the most common, and they require emergent management to prevent avascular necrosis of the femoral head. Knee dislocations are uncommon but potentially dangerous injuries that can result in amputation due to the potential for missed secondary injury, especially if they are reduced spontaneously. Isolated ankle dislocations are relatively rare, as most ankle dislocations involve an associated fracture...
December 20, 2017: Emergency Medicine Practice
https://www.readbyqxmd.com/read/29260700/-slipped-capital-femoral-epiphysis-is-diagnosed-too-late
#4
Anders Elneff Graversen, Niels Wisbech Pedersen, Roland Knudsen
Slipped capital femoral epiphysis (SCFE) is a serious orthopaedic hip disease in the adolescent population. It has a prevalence of 10.8 per 100.000 children and usually occurs in children 9-16 years of age. Despite focus on delay of the diagnosis, no improvements have been made. An adolescent complaining of stress-related pain in the hip, groin, thigh or knee should be suspected of having SCFE, until an X-ray has excluded this diagnosis. Delayed diagnosis may have serious consequences in terms of further displacement of the femoral head and risk of increased avascular necrosis...
December 11, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29242788/obturator-dislocation-of-hip-with-ipsilateral-fracture-neck-femur-a-case-report
#5
Sumit Kumar Jain, Parit Aggarwal, Arun Yadav
Introduction: Traumatic dislocation of the hip with ipsilateral fracture neck femur is a rare injury because of the different mechanism of both these injuries. The management of such injuries is a challenge as the chances of nonunion and avascular necrosis of femoral head are very high with fixation methods. We report a case of obturator dislocation of the hip with ipsilateral fracture neck of the femur which was treated with uncemented total hip replacement. Case Report: A 32-year-old male sustained obturator dislocation with ipsilateral fracture neck femur following road traffic accident...
September 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29228594/bone-strengthening-pill-bsp-promotes-bone-cell-and-chondrocyte-repair-and-the-clinical-and-experimental-study-of-bsp-in-the-treatment-of-osteonecrosis-of-the-femoral-head
#6
Zheng Li, Lulin Wang, Jin Wei, Liguo Zhu, Xisheng Weng, Jin Jin, Hong Xiao, Jun Zhang, Heming Wang, Guantong Shi, Lingpeng Pei, Fangde Zou, Wanqiang Zhang, Tianzun Tao, Xin Dong
About 1 in 3 people suffer from bone and joint disease, which is a disease of bone and cartilage cells. Osteonecrosis of the femoral head (ONFH) is a typical example of bone and joint disease involving bone cell necrosis. Osteonecrosis of the femoral head leads to the occurrence of premature osteoarthritis of the hip and collapse of the cartilage cells, and there is currently no effective drug treatment available. In order to study the effects of "bone-strengthening pill" (BSP) on the repair of bone and cartilage cells, we investigated the potential effects of the herbal mixture BSP in an animal model of avascular necrosis of the femoral head and in patients...
November 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/29207081/increased-serum-protein-levels-by-yuanshi-shengmai-chenggu-tablet-in-treatment-of-avascular-osteonecrosis-of-the-femoral-head
#7
Jianchun Zeng, Peng Deng, Jie Li, Wenjun Feng, Jinlun Chen, Yirong Zeng
The traditional Chinese medicine (TCM) Yuanshi Shengmai Chenggu Tablet is used for treating the common orthopedic disease, hormone‑induced avascular necrosis of the femoral head (ANFH) in China. However, its underlying mechanism and the changes induced in the treatment of ANFH remain to be fully elucidated. In the present study, through the use of isobaric Tag for Relative and Absolute Quantitation and multiple reaction monitoring quantifications, corticosteroid‑induced femoral head necrosis and the effects of treatment with Yuanshi Shengmai Chenggu Tablet were examined...
November 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29203431/surgical-reduction-of-congenital-hip-dislocation
#8
REVIEW
C Glorion
Surgical reduction of congenital hip dislocation is technically challenging. In our practice, surgical reduction is usually reserved for patients who have failed non-operative treatment, which is the first-line strategy. However, primary surgery may be indicated if the dislocation is diagnosed late and can be performed until 8 years of age. The reduction step is crucial. It starts with painstaking exposure of the capsule. Identifying the lower part of the acetabulum is the key to accurate repositioning of the epiphysis...
December 1, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29192936/outcomes-of-femoral-head-marrow-stimulation-techniques-at-minimum-2-year-follow-up
#9
David E Hartigan, Itay Perets, Edwin O Chaharbakhshi, John P Walsh, Leslie C Yuen, Benjamin G Domb
This study compared patients who underwent femoral head microfracture with a control group of patients who did not require microfracture. Patients had more than 2 years of follow-up. The patient groups had similar demographic and radiographic features, including sex, age within 5 years, body mass index within 5 points, equal Tönnis grade, lateral center edge angle within 5°, labral treatment, and capsular closure vs release. Inclusion criteria were a minimum of 2 years of follow-up, Outerbridge grade IV cartilage damage, and femoral head marrow stimulation technique performed at the time of arthroscopy...
November 30, 2017: Orthopedics
https://www.readbyqxmd.com/read/29185671/managing-dislocations-of-the-hip-knee-and-ankle-in-the-emergency-department
#10
Caylyne Arnold, Zane Fayos, David Bruner, Dylan Arnold
Dislocation of the major joints of the lower extremities--hip, knee, and ankle--can occur due to motor-vehicle crashes, falls, and sports injuries. Hip dislocations are the most common, and they require emergent management to prevent avascular necrosis of the femoral head. Knee dislocations are uncommon but potentially dangerous injuries that can result in amputation due to the potential for missed secondary injury, especially if they are reduced spontaneously. Isolated ankle dislocations are relatively rare, as most ankle dislocations involve an associated fracture...
December 2017: Emergency Medicine Practice
https://www.readbyqxmd.com/read/29181581/evaluation-of-femoral-head-viability-via-bone-scintigraphy-in-the-postoperative-pediatric-patient
#11
Ashishkumar K Parikh, Eleby R Washington, Adam J Bobbey, Stephanie E Spottswood
BACKGROUND: Evaluating postoperative patients with hardware is challenging following surgical intervention for hip maladies such as femoral neck fractures and slipped capital femoral epiphysis (SCFE). These children are at increased risk of developing avascular necrosis, and imaging may be requested to confirm or exclude this diagnosis. Children with Legg-Calvé-Perthes disease can be monitored for restoration of blood flow to the capital femoral epiphysis to guide management and help with prognosis...
November 27, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29181188/intra-articular-osteochondroma-of-the-posteroinferior-femoral-neck-associated-with-hip-joint-osteochondromatosis-a-case-report
#12
Sung Il Wang, Eun Hae Park, Sun Jung Yoon, Jung Ryul Kim
Osteochondromas are usually extra-articular lesions originating from the metaphysis of long bones. Intra-articular osteochondromas may also occur, causing pain and discomfort and restricting the range of motion. Osteochondromas of the femoral neck are intra-articular lesions that are difficult to access for surgical resection, particularly when located posteriorly. We herein present a rare case of an intra-articular osteochondroma involving the posteroinferior aspect of the femoral neck associated with secondary synovial osteochondromatosis (SOC) of the hip joint in a 25-year-old woman...
November 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29162080/modifications-to-advanced-core-decompression-for-treatment-of-avascular-necrosis-of-the-femoral-head
#13
Stefan Landgraeber, Sebastian Warwas, Tim Claßen, Marcus Jäger
BACKGROUND: "Advanced Core Decompression" (ACD) is a new technique for treatment of osteonecrosis of the femoral head (ONFH) that includes removal of the necrotic tissue using a percutaneous expandable reamer followed by refilling of the drill hole and the defect with an injectable, hard-setting, composite calcium sulphate (CaSO4)-calcium phosphate (CaPO4) bone graft substitute. As autologous bone has been shown to be superior to all other types of bone grafts, the aim of the study is to present and evaluate a modified technique of ACD with impaction of autologous bone derived from the femoral neck into the necrotic defect...
November 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29148018/lightbulb-technique-for-the-treatment-of-osteonecrosis-of-the-femoral-head
#14
Cemil Yildiz, Yusuf Erdem, Kenan Koca
INTRODUCTION: The aim of this study was to report the clinical and radiological outcomes for 21 patients (28 hips) treated for osteonecrosis of the femoral head using the lightbulb technique, a nonvascularised bone grafting technique. METHODS: The study group included 14 men and 7 women, with a mean age of 33.2 (range 22-50) years, presenting with avascular necrosis of the femoral head of stage 4a or earlier, according to the Steinberg classification. Patients were treated using the nonvascularised lightbulb bone grafting technique...
November 15, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29131775/traumatic-hip-dislocation-what-the-orthopedic-surgeon-wants-to-know
#15
Jacob C Mandell, Richard A Marshall, Michael J Weaver, Mitchel B Harris, Aaron D Sodickson, Bharti Khurana
Hip dislocation is an important orthopedic emergency usually seen in young patients who have experienced high-energy trauma, often resulting in significant long-term morbidity. Rapid identification and reduction is critical, as prolonged dislocation increases the risk of developing avascular necrosis of the femoral head, and posttraumatic osteoarthritis is a common complication, even in the absence of associated fractures. Identification and timely management of hip dislocation are highly dependent on imaging, both at presentation and after attempted reduction...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29126401/dyslipidaemia-for-patients-with-low-energy-femoral-neck-fractures-after-the-treatment-of-cancellous-screws-a-retrospective-study-with-a-3-year-minimum-follow-up
#16
Chi Zhang, Xiaoxiao Zhu, Genwang Pei, Ping Xu, Xianshang Zeng, Lili Zhang, Nan Zhang, Dan Zeng, Lei Cao, Weiguang Yu, Xinchao Zhang
BACKGROUND: Avascular necrosis of the femoral head (AVNFH) occurs infrequently following femoral neck fracture. The association between AVNFH and dyslipidaemia remains controversial. Although major risk factors for AVNFH have been proposed, most of them remain under discussion. Our purpose herein was to evaluate the association between dyslipidaemia and AVNFH following low-energy femoral neck fractures treated with cancellous screws in elderly patients in our tertiary care centre. METHODS: Four hundred and seventy-two consecutive patients (472 hips) with low-energy femoral neck fractures were identified and treated with cancellous screws from July 2007 to April 2013...
November 10, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29117211/the-treatment-of-femoral-neck-fracture-using-vegf-loaded-nanographene-coated-internal-fixation-screws
#17
Shuo Li, Hengfeng Yuan, Jianfeng Pan, Wenshuai Fan, Liang Zhu, Zuoqin Yan, Changan Guo
PURPOSE: Previous studies have proved that vascular endothelial growth factor (VEGF) has a dual role in the promotion of new bone formation and blood vessel repair during fracture healing. However, how to introduce VEGF to a fracture site safely and effectively is still a challenge. This study aimed to prepare a VEGF-loaded nanographene coated internal fixation screw and to evaluate its effects in the treatment of femoral neck fracture. METHODS: Nanographene coated screws were prepared by direct liquid-phase exfoliation of the graphite method, and the surface characteristics were observed through scanning electron microscopy (SEM)...
2017: PloS One
https://www.readbyqxmd.com/read/29115490/microrna%C3%A2-206-contributes-to-the-progression-of-steroid%C3%A2-induced-avascular-necrosis-of-the-femoral-head-by-inducing-osteoblast-apoptosis-by-suppressing-programmed-cell-death-4
#18
Zaiheng Zhang, Anmin Jin, Denglu Yan
The expression of microRNA‑206 (miR‑206) is aberrantly induced in steroid‑induced avascular necrosis of femoral head (SANFH). Therefore, investigating the function of miR‑206 in SANFH and uncovering the functional mechanism associated with the condition will promote the understanding and treatment of the disease. The purpose of the present study was to investigate the pro‑osteoclasteogenic effect of miR‑206 that occurs through regulation of programmed cell death 4 (PDCD4). The expression of miR‑206 and PDCD4 was analyzed in the clinical SANFH specimens...
November 3, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29105637/detection-of-ad-bmp-2-ires-hif-1%C3%AE-mu-on-local-promoting-angiogenic-and-osteogenic-capacity-of-necrosis-area
#19
Fuai Cui, Xiuli Wang, Wei Wang, Peng Xiao, Yuan Ma, Lindong Jiang
The induced EPCs were transfected by Ad-BMP-2-IRES-HIF-1αmu, and then transplanted into femoral head necrotic zone, the effect on osteogenesis and agiogenesis of necrosis zone was detected. The Ad-BMP-2-IRES-HIF-1α was transfected into induced EPCs and then transplanted into avascular necrotic parts of the femoral head (ANFH).Afterwards, the promotion effect on angiogenic and osteogenic capabilities of the necrosis parts from Ad-BMP-2-IRES-HIF-1α was detected. Rabbit bone marrow MNCs were obtained by density gradient centrifugation method, and were induced into EPCs by M199 medium; EPCs were identified in accordance with the cell morphology, specific surface markers and uptake abilities...
September 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29083360/management-and-treatment-of-femoral-neck-stress-fractures-in-recreational-runners-a-report-of-four-cases-and-review-of-the-literature
#20
Carlo Biz, Antonio Berizzi, Alberto Crimì, Chiara Marcato, Giulia Trovarelli, Pietro Ruggieri
Femoral neck stress fractures (FNSFs) in healthy young subjects are uncommon and most prevalent among long-distance runners and military recruits. Women seem to be at higher risk of developing stress fractures because of possible eating disorders followed by amenorrhea and osteoporosis. This case report describes four young and middle-aged, active female recreational runners who developed stress fractures of the femoral neck. In three of them, with a clinical history of persistent pain in the groin region, which worsened during training, early diagnosis by MRI was considered essential in detecting the fractures...
October 18, 2017: Acta Bio-medica: Atenei Parmensis
keyword
keyword
114043
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"