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JOURNAL ARTICLE
Ruvistay Gutierrez-Arias, Gabriel Salgado-Maldonado, Paola Letelier Valdivia, Francisco Salinas-Barahona, Carmen Echeverría-Valdebenito, Pamela Seron
INTRODUCTION: The high-flow nasal cannula (HFNC) has become a widely used respiratory support system, which has proven to be effective in different populations. The facilitation of oral communication and feeding have been described as advantages of this support. Nevertheless, swallowing disorders associated with the use of HFNC have been postulated. However, such evidence is scattered in the literature, not systematically searched, and needs to be adequately summarised. This review aimed to explore the literature, to identify and map the evidence, regarding the frequency and methods of assessment of swallowing disorders in adult HFNC users, in both critical and non-critical units...
2023: PloS One
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JOURNAL ARTICLE
Zemeng Li, Yanhai Meng, Lulu Li, Yanbo Zhang
Acute respiratory distress syndrome (ARDS) continues to be one of the most life-threatening conditions for patients in the intensive care unit (ICU). The 2023 European Society of Intensive Care Medicine guidelines on ARDS: definition, phenotyping and respiratory support strategies (2023 Guideline) update the 2017 An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine clinical practice guideline: mechanical ventilation in adult patients with ARDS (2017 Guideline), including 7 aspects of 3 topics of definitions, phenotyping, and respiratory support strategies [including high flow nasal cannula oxygen (HFNO), non-invasive ventilation (NIV), neuromuscular blocking agents (NMBA), extracorporeal life support (ECLS), positive end-expiratory pressure (PEEP) with recruitment maneuvers (RM), tidal volume (VT), and prone positioning]...
September 2023: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
#23
REVIEW
Giovanni Ceschia, Mattia Parolin, Germana Longo, Claudio Ronco, Enrico Vidal
Hyperammonemia is a life-threatening condition mainly due to the neurotoxicity of ammonia. Ammonia scavengers may be insufficient, and extracorporeal treatment may be required. Continuous treatments are preferred, and a high-dose continuous renal replacement therapy (CRRT) must be prescribed to ensure a fast ammonia depletion. Many of the children with hyperammonemia are newborns, with lower blood volume than older children. The majority of the CRRT systems are adult-based, with large extracorporeal priming volumes and inadequate UF control...
2023: Blood Purification
#24
JOURNAL ARTICLE
Peter Lawlor, Leila Cohen, Samantha Rose Adeli, Ella Besserer, Valérie Gratton, Rebekah Murphy, Grace Warmels, Adrianna Bruni, Monisha Kabir, Chelsea Noel, Brandon Heidinger, Koby Anderson, Kyle Arsenault-Mehta, Krista Wooller, Julie Lapenskie, Colleen Webber, Daniel Bedard, Paula Enright, Isabelle Desjardins, Khadija Bhimji, Claire Dyason, Akshai Iyengar, Shirley H Bush, Sarina Isenberg, Peter Tanuseputro, Brandi Vanderspank-Wright, James Downar, Henrique Parsons
OBJECTIVE: To compare comorbidities, symptoms and end-of-life (EoL) palliative medication (antisecretories, opioids, antipsychotics and sedatives) use among decedents before and during the COVID-19 pandemic. DESIGN: In a retrospective cohort study, decedent records in three acute care hospitals were abstracted, generating a prepandemic (November 2019-February 2020) group (pre-COVID) and two intrapandemic (March-August 2020, wave 1) groups, one without (COVID-ve) and one with COVID-19 infection (COVID+ve)...
September 5, 2023: BMJ Open
#25
JOURNAL ARTICLE
L Martí-Hereu, G Navarra-Ventura, A M Navas-Pérez, S Férnandez-Gonzalo, F Pérez-López, C de Haro-López, G Gomà-Fernández
INTRODUCTION: The usage of immersive virtual reality (iVR) in the context of an intensive care unit (ICU) is scarce. Our objective was to assess the feasibility of the usage of iVR in critical patients with or without mechanical ventilation (MV) and to determine the anxiety degree before and after each session. METHODS: Analytical, descriptive, prospective, and cross-sectional research. Pilot test with 20 patients from a polyvalent ICU of a tertiary hospital. Adult patients were included, either connected or not to MV, watchful and calmed (RASS -1/+1) and without delirium (negative CAM-ICU)...
August 28, 2023: Enfermería intensiva
#26
JOURNAL ARTICLE
(no author information available yet)
Tracheostomy is a common procedure in critically ill patients who require mechanical ventilation. Tracheostomies have several advantages over endotracheal tubes, including less sinusitis or pharyngeal injuries, fewer sedative drugs, improved oropharyngeal hygiene, easier communication, more comfort, preservation of vocal cord function, and so on. However, patients with a tracheostomy require high quality care and often suffer from dysphagia, dysphonia, tracheal stenosis, or excessive airway secretions, etc ...
August 9, 2023: Chinese Journal of Tuberculosis and Respiratory Diseases
#27
JOURNAL ARTICLE
Osama Alanazi, Jie Li
BACKGROUND: Aerosol delivery via high-flow nasal cannula (HFNC) has gained popularity due to the increased use of the modality for treating hypoxemic and hypercapnic respiratory failure. Various HFNC devices are available in the United States; however, the effectiveness of aerosol delivery via HFNC devices remains unclear. Thus, this study aimed to investigate the impact of various commercially available devices on transnasal aerosol delivery. METHODS: This was a bench study that used a 2-chamber lung model, in which one chamber was connected to an adult manikin with anatomically correct upper-airway proportions...
November 25, 2023: Respiratory Care
#28
REVIEW
Leigh D White, Ruan A Vlok, Christopher Yc Thang, David H Tian, Thomas M Melhuish
BACKGROUND: Apnoeic oxygenation is the delivery of oxygen during the apnoeic phase preceding intubation. It is used to prevent respiratory complications of endotracheal intubation that have the potential to lead to significant adverse events including dysrhythmia, haemodynamic decompensation, hypoxic brain injury and death. Oxygen delivered by nasal cannulae during the apnoeic phase of intubation (apnoeic oxygenation) may serve as a non-invasive adjunct to endotracheal intubation to decrease the incidence of hypoxaemia, morbidity and mortality...
August 2, 2023: Cochrane Database of Systematic Reviews
#29
JOURNAL ARTICLE
Fleur-Stefanie L I M van der Ven, Christel M A Valk, Siebe Blok, Michelle G Brouwer, Dai Ming Go, Amanda Lokhorst, Pien Swart, David M P van Meenen, Frederique Paulus, Marcus J Schultz
BACKGROUND: High-flow nasal oxygen (HFNO) is increasingly used in patients with acute hypoxemic respiratory failure. It is uncertain whether a broadened Berlin definition of acute respiratory distress syndrome (ARDS), in which ARDS can be diagnosed in patients who are not receiving ventilation, results in similar groups of patients receiving HFNO as in patients receiving ventilation. METHODS: We applied a broadened definition of ARDS in a multicenter, observational study in adult critically ill patients with acute hypoxemic respiratory failure due to coronavirus disease 2019 (COVID-19), wherein the requirement for a minimal level of 5 cm H2 O PEEP with ventilation is replaced by a minimal level of airflow rate with HFNO, and compared baseline characteristics and outcomes between patients receiving HFNO and patients receiving ventilation...
July 14, 2023: Annals of Intensive Care
#30
JOURNAL ARTICLE
Jie Li, Kai Liu, Shan Lyu, Guoqiang Jing, Bing Dai, Rajiv Dhand, Hui-Ling Lin, Paolo Pelosi, Ariel Berlinski, Jordi Rello, Antoni Torres, Charles-Edouard Luyt, Jean-Bernard Michotte, Qin Lu, Gregory Reychler, Laurent Vecellio, Armèle Dornelas de Andrade, Jean-Jacques Rouby, James B Fink, Stephan Ehrmann
BACKGROUND: Clinical practice of aerosol delivery in conjunction with respiratory support devices for critically ill adult patients remains a topic of controversy due to the complexity of the clinical scenarios and limited clinical evidence. OBJECTIVES: To reach a consensus for guiding the clinical practice of aerosol delivery in patients receiving respiratory support (invasive and noninvasive) and identifying areas for future research. METHODS: A modified Delphi method was adopted to achieve a consensus on technical aspects of aerosol delivery for adult critically ill patients receiving various forms of respiratory support, including mechanical ventilation, noninvasive ventilation, and high-flow nasal cannula...
July 12, 2023: Annals of Intensive Care
#31
JOURNAL ARTICLE
Ilaria Alice Crippa, Jean-Louis Vincent, Federica Zama Cavicchi, Selene Pozzebon, Nicolas Gaspard, Christelle Maenhout, Jacques Creteur, Fabio Silvio Taccone
BACKGROUND: Sepsis-associated brain dysfunction (SABD) is frequent and is associated with poor outcome. Changes in brain hemodynamics remain poorly described in this setting. The aim of this study was to investigate the alterations of cerebral perfusion pressure and intracranial pressure in a cohort of septic patients. METHODS: We conducted a retrospective analysis of prospectively collected data in septic adults admitted to our intensive care unit (ICU). We included patients in whom transcranial Doppler recording performed within 48 h from diagnosis of sepsis was available...
July 7, 2023: Neurocritical Care
#32
JOURNAL ARTICLE
Eloïse de Beaufort, Guillaume Carteaux, François Morin, Arnaud Lesimple, Anne-Fleur Haudebourg, Emeline Fresnel, Damien Duval, Alexandre Broc, Alain Mercat, Laurent Brochard, Dominique Savary, François Beloncle, Armand Mekontso Dessap, Jean-Christophe Richard
BACKGROUND: Several noninvasive ventilatory supports rely in their design on high oxygen consumption which may precipitate oxygen shortage, as experienced during the COVID-19 pandemic. In this bench-to-bedside study, we assessed the performance of a new continuous positive airway pressure (CPAP) device integrating a large reservoir ("Bag-CPAP") designed to minimize oxygen consumption, and compared it with other CPAP devices. METHODS: First, a bench study compared the performances of Bag-CPAP and four CPAP devices with an intensive care unit ventilator...
July 4, 2023: Critical Care: the Official Journal of the Critical Care Forum
#33
JOURNAL ARTICLE
Asem Alnajada, Bronagh Blackwood, Ben Messer, Ivan Pavlov, Murali Shyamsundar
(1) Background: High-flow nasal therapy (HFNT) has shown several benefits in addressing respiratory failure. However, the quality of evidence and the guidance for safe practice are lacking. This survey aimed to understand HFNT practice and the needs of the clinical community to support safe practice. (2) Method: A survey questionnaire was developed and distributed to relevant healthcare professionals through national networks in the UK, USA and Canada; responses were collected between October 2020 and April 2021...
June 8, 2023: Journal of Clinical Medicine
#34
JOURNAL ARTICLE
Giacomo Grasselli, Carolyn S Calfee, Luigi Camporota, Daniele Poole, Marcelo B P Amato, Massimo Antonelli, Yaseen M Arabi, Francesca Baroncelli, Jeremy R Beitler, Giacomo Bellani, Geoff Bellingan, Bronagh Blackwood, Lieuwe D J Bos, Laurent Brochard, Daniel Brodie, Karen E A Burns, Alain Combes, Sonia D'Arrigo, Daniel De Backer, Alexandre Demoule, Sharon Einav, Eddy Fan, Niall D Ferguson, Jean-Pierre Frat, Luciano Gattinoni, Claude Guérin, Margaret S Herridge, Carol Hodgson, Catherine L Hough, Samir Jaber, Nicole P Juffermans, Christian Karagiannidis, Jozef Kesecioglu, Arthur Kwizera, John G Laffey, Jordi Mancebo, Michael A Matthay, Daniel F McAuley, Alain Mercat, Nuala J Meyer, Marc Moss, Laveena Munshi, Sheila N Myatra, Michelle Ng Gong, Laurent Papazian, Bhakti K Patel, Mariangela Pellegrini, Anders Perner, Antonio Pesenti, Lise Piquilloud, Haibo Qiu, Marco V Ranieri, Elisabeth Riviello, Arthur S Slutsky, Renee D Stapleton, Charlotte Summers, Taylor B Thompson, Carmen S Valente Barbas, Jesús Villar, Lorraine B Ware, Björn Weiss, Fernando G Zampieri, Elie Azoulay, Maurizio Cecconi
The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients' representatives on behalf of the ESICM...
June 16, 2023: Intensive Care Medicine
#35
JOURNAL ARTICLE
Abdul Hakeem Al Hashim, Abdullah Al Reesi, Nabil M Al Lawati, Jyoti Burad, Murtadha Al Khabori, Juhi Chandwani, Redha Al Lawati, Yahya Al Masroori, Abdul Aziz Al Balushi, Salim Al Masroori, Khalsa Al Siyabi, Fatema Al Lawati, Faroug Yousif Nimer Ahmed, Merah Al Busaidy, Aisha Al Huraizi, Mahmood Al Jufaili, Jalila Al Zaabi, Jerin Treesa Varghese, Ruqaya Al Harthi, Kingsly Prabhakaran Sebastian, Fahad Hamed Al Abri, Jamal Al Aghbari, Saif Al Mubaihsi, Adil Al Lawati, Mujahid Al Busaidi, Giuseppe Foti
OBJECTIVES: For COVID-19-related respiratory failure, noninvasive respiratory assistance via a high-flow nasal cannula (HFNC), helmet, and face-mask noninvasive ventilation is used. However, which of these options is most effective is yet to be determined. This study aimed to compare the three techniques of noninvasive respiratory support and to determine the superior technique. DESIGN: A randomized control trial with permuted block randomization of nine cases per block for each parallel, open-labeled arm...
June 13, 2023: Critical Care Medicine
#36
JOURNAL ARTICLE
Yannick Binois, Marie Renaudier, Florence Dumas, Younès Youssfi, Frankie Beganton, Daniel Jost, Lionel Lamhaut, Eloi Marijon, Xavier Jouven, Alain Cariou, Wulfran Bougouin
BACKGROUND: Out-of-hospital cardiac arrest (OHCA) is a common cause of death. Early circulatory failure is the most common reason for death within the first 48 h. This study in intensive care unit (ICU) patients with OHCA was designed to identify and characterize clusters based on clinical features and to determine the frequency of death from refractory postresuscitation shock (RPRS) in each cluster. METHODS: We retrospectively identified adults admitted alive to ICUs after OHCA in 2011-2018 and recorded in a prospective registry for the Paris region (France)...
June 9, 2023: Annals of Intensive Care
#37
JOURNAL ARTICLE
Katrijn Daenen, Jilske A Huijben, Anders Boyd, Lieuwe D J Bos, Sara C M Stoof, Hugo van Willigen, Diederik A M P J Gommers, Hazra S Moeniralam, Corstiaan A den Uil, Nicole P Juffermans, Merijn Kant, Abraham J Valkenburg, Janesh Pillay, David M P van Meenen, Frederique Paulus, Marcus J Schultz, Virgil A S H Dalm, Eric C M van Gorp, Janke Schinkel, Henrik Endeman
BACKGROUND: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose corticosteroids are often administered as salvage late in the disease course, whereas earlier administration may be more beneficial in preventing disease progression. Previous research has revealed that increased levels of various biomarkers are associated with mortality, and whole blood transcriptome sequencing has the ability to identify host factors predisposing to critical illness in patients with COVID-19...
June 2, 2023: JMIR Research Protocols
#38
REVIEW
Yorschua Jalil, Martina Ferioli, Martin Dres
During the COVID-19 pandemic, the use of non-invasive respiratory support (NIRS) became crucial in treating patients with acute hypoxemic respiratory failure. Despite the fear of viral aerosolization, non-invasive respiratory support has gained attention as a way to alleviate ICU overcrowding and reduce the risks associated with intubation. The COVID-19 pandemic has led to an unprecedented increased demand for research, resulting in numerous publications on observational studies, clinical trials, reviews, and meta-analyses in the past three years...
May 16, 2023: Journal of Clinical Medicine
#39
JOURNAL ARTICLE
Alexis Ferré, Myriam Lamamri, Marc Delord, Georges Abi-Abdallah, Antoine Gros, Guillaume Lacave, Virginie Laurent, Fabien Marquion, Sybille Merceron, Marine Paul, Gilles Troché, Raphaele Convers-Domart, Stéphanie Marque-Juillet, Stéphane Legriel, Fabrice Bruneel
BACKGROUND: This study was carried out to compare characteristics and outcomes in patients with acute respiratory failure related to COVID-19 during first, second, and third waves. METHODS: We included consecutive adults admitted to the intensive care unit between March 2020 and July 2021. We compared three groups defined by the epidemic intake phase: waves 1 (W1), 2 (W2), and 3 (W3). RESULTS: We included 289 patients. Two hundred and eight (72%) patients were men with a median age of 63 years (IQR: 54-72), of whom 68 (23...
May 23, 2023: Respiration; International Review of Thoracic Diseases
#40
JOURNAL ARTICLE
Kiattichai Daorattanachai, Chachchom Hirunrut, Pattarin Pirompanich, Sinee Weschawalit, Winchana Srivilaithon
BACKGROUND: The monocyte distribution width (MDW), a novel inflammatory biomarker reflecting morphological changes in response to inflammation, has been shown to be useful in identifying COVID-19 infection or predicting death. However, data on the association with predicting the need for respiratory support are still limited. The aim of this study was to determine the association of MDW with the need for respiratory support in patients with SARS-CoV-2 infection. PATIENTS AND METHODS: This is a single-center retrospective cohort study...
May 2023: Indian Journal of Critical Care Medicine
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