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nasopharingeal carcinoma

Fabio Veronese, Eros Montin, Paolo Potepan, Luca T Mainardi
In this study we developed a technique to improve the identification of carcinoma and pathological lymph nodes in cases of Nasopharingeal Carcinoma (NPC), through a quantitative characterization of the tissues based on MR images: 3D VIBE (Volumetric Interpolated Breath-hold Examination) T1-CE (Contrast Enhanced), T1, T2 and Diffusion Weighted Imaging (DWI) for b-values 0,300,500,700,1000. The procedure included two phases: 1) coregistration of volumes and 2) tissue characterization. Concerning the first phase, the DICOM images were reassembled spatially and resampled with isotropic 0...
2012: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
S Cavalieri, C Feliciani, G Massi, G Addolorato, G Gasbarrini, P Amerio, M Rotoli
The term lymphoepithelioma-like carcinoma identifies a group of nasopharingeal epithelial tumors characterized by aggregates of malignant undifferentiated cells surrounded by a dense reactive lymphoplasmacellular infiltrate. Primary cutaneous localization is rare, with approximately 30 cases reported in literature. We describe a case of primary lymphoepithelioma-like carcinoma of the skin in a 92-year-old woman. Immunohistochemical examination was positive for cytokeratine (KL1 and EMA) as regards epithelial cells, while the lymphocitic infiltrate was positive for LCA and CD3...
October 2007: International Journal of Immunopathology and Pharmacology
E Gabusi, C Lattes, M Fiorentino, A D'Errico, W F Grigioni
Nasopharingeal carcinoma (NPC) is frequently associated with Epstein-Barr virus (EBV), but little is known about its pathogenesis in Western countries, where its incidence is low and EBV is not endemic. We studied 26 Italian cases of NPC: 24 of the non-keratinizing subtype, and 2 keratinizing. We used immunohistochemistry to evaluate p53, bcl-2 and Ki-67 protein expression, and in situ hybridization (ISH) to assess bcl-2 mRNA and the EBV transcript, EBER1, with bcl-2 protein and mRNA expression being compared in serial sections...
September 2001: Journal of Experimental & Clinical Cancer Research: CR
N Toledano Fernández, S García Sáenz, E Corredera Salinero, A Arteaga Sánchez, D Díaz Valle
PURPOSE/MATERIAL AND METHOD: To report a clinical case of a 64 year-old man with orbital involvement from a nasopharyngeal carcinoma. Relevant clinical and imaging (CT and MNR) data are reviewed. CLINICAL CASE/CONCLUSION: Nasopharyngeal carcinoma is an unusual tumor (0.25% of all malignant tumors), being most common the hystologically undifferentiated subtype. The orbit may become affected from expansion of this type of neoplasm. Frequence of tumor's ophthalmologic manifestations and different therapeutic approaches are discussed...
November 2001: Archivos de la Sociedad Española de Oftalmología
C Glanzmann, H G Aberle, W Horst
5-year cure rates after radiotherapy of nasopharingeal carcinomas in the own patients are reported. The 5-year cure rate in squamous cell carcinoma is about 30% and in lymphoepithelial carcinoma Schmincke-Regaud about 50%. These results are comparable to those which are published in the recent literature. The base of the skull should be included in the high-dose volume even in T1 and T2 cases.
October 1976: Strahlentherapie
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