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Mahendra Rai, Avinash P Ingle, Raksha Pandit, Priti Paralikar, Indarchand Gupta, Marco V Chaud, Carolina Alves Dos Santos
Now-a-days development of microbial resistancce have become one of the most important global public health concerns. It is estimated that about 2 million people are infected in USA with multidrug resistant bacteria and out of these, about 23,000 die per year. In Europe, the number of deaths associated with infection caused by MDR bacteria is about 25,000 per year, However, the situation in Asia and other devloping countries is more critical. Considering the increasing rate of antibiotic resistance in various pathogens, it is estimated that MDR organisms can kill about 10 million people every year by 2050...
September 1, 2017: International Journal of Pharmaceutics
Fatma Sirmatel, Nimet Sahin, Ocal Sirmatel, Ender Telli, Sükrü Kececi
The present study examined the use of antibiotics with respect to the rate of Chlamydia trachomatis positivity. Our subjects were 282 sexually active Turkish females between the ages of 15 and 42. Endocervical samples were investigated in 60 women with pelvic inflammatory diseases (PIDs), 90 infertile patients (IPs), 92 registered commercial sex workers (CSWs), and 40 intrauterine device (IUD) users. All samples were analyzed using direct immunofluorescence test techniques for the presence of C. trachomatis antigen, which was found in 12...
February 2005: Japanese Journal of Infectious Diseases
G E Afinogenov, E F Panarin, E P Anan'eva
The antimicrobial effect of cationic surface-active substances, such as cetylpyridinyi chloride, alkylmethylbenzylammonium chloride ("roccal" and "catamine AB") and chlorhexidine was studied in vitro. The above compounds had a high bactericidal activity against poly-resistant staphylococcal strains. In non-bactericidal concentrations they significantly increased the efficacy of antibiotcs with different modes of action, i.e. penicillins, tetracyclines, amino-glycosides, macrolides. The effect of the cationic surface-active substances increasing the antibiotic activity against staphylococci did not depend on the resistance type, i...
June 1977: Antibiotiki
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