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IBS and diet

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https://www.readbyqxmd.com/read/28480865/impact-of-food-enriched-with-dietary-fiber-on-patients-with-constipation-predominant-irritable-bowel-syndrome
#1
G Sulaberidze, M Okujava, K Liluashvili, M Tughushi, M Abramashvili
The causes of motility disorder of gastrointestinal tract and in particular Irritable Bowel Syndrome IBS are multifold, leading to complexity of treatment and requirement of more precise investigation of different pharmacological and non-pharmacological approaches. The aim of the study was investigation and comparison of the dietary fiber intake among women with constipation-predominant irritable bowel syndrome (IBS-C) and without, improvement of the dietary fiber intake using interventions with less rough changes of food related behavior and study of its effects on the bowel function, general wellbeing and compliance of patients...
March 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28462704/the-role-of-dietary-approach-in-irritable-bowel-syndrome
#2
Piero Portincasa, Antony Lembo, Ornella De Bari, Domenica M Di Palo, Anna Maggio, Ilaria Cataldo, Giuseppe Calamita
Irritable bowel syndrome (IBS) is a chronic functional disorder of the gastrointestinal tract and is one of the most frequent gastrointestinal diseases. In IBS multiple pathophysiological mechanisms including alterations in intestinal motility, permeability, nutrient absorption, and intestinal microbiota have been implicated. Foods are commonly reported by patients to be a trigger of symptoms and therefore are likely involved in the generation of symptoms in IBS. Among all possible therapeutic options, a first-line approach to IBS is dietary education and identification of foods potentially responsible for the onset or worsening of symptoms...
April 27, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28445436/irritable-bowel-syndrome-clinical-manifestations-dietary-influences-and-management
#3
REVIEW
Ronald Ikechi, Bradford D Fischer, Joshua DeSipio, Sangita Phadtare
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is characterized by symptoms of chronic abdominal pain and altered bowel habits in the absence of an overtly identifiable cause. It is the most commonly diagnosed functional gastrointestinal disorder, accounting for about one third of gastroenterology visits. It generally presents as a complex of symptoms, including psychological dysfunction. Hypersensitivity to certain foods, especially foods that contain high amounts of fructose, plays a role in the pathophysiology of IBS...
April 26, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28440580/systematic-review-quality-of-trials-on-the-symptomatic-effects-of-the-low-fodmap-diet-for-irritable-bowel-syndrome
#4
REVIEW
L R Krogsgaard, M Lyngesen, P Bytzer
BACKGROUND: The low Fermentable Oligo-, Di- Monosaccharides, and Polyoles (FODMAP) diet is a new treatment option for irritable bowel syndrome (IBS). Experts refer to the diet as supported by high level of evidence, but an evaluation of the quality of trials is lacking. AIM: To provide a systematic review of the quality of trials on the symptomatic effects of the low FODMAP diet for IBS. METHODS: Pubmed and EMBASE were searched for randomised controlled trials (RCTs) reporting effect of the low FODMAP diet on IBS symptoms...
April 25, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28422780/understanding-the-gut-microbiota-in-inflammatory-and-functional-gastrointestinal-diseases
#5
Johanna Sundin, Lena Öhman, Magnus Simren
OBJECTIVE: During the last decade experimental and observational studies have shown that patients with Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS) may have an altered intestinal microbial composition compared to healthy subjects. However, no uniform microbial signature has as yet been detected for either IBD or IBS. This review summarizes the current knowledge of microbial dysbiosis, and its potential relationship to the pathophysiology in IBD and IBS. METHODS: A selective review was conducted to summarize the current knowledge of gut microbiota in the pathophysiology of IBD and IBS...
April 18, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28416515/multivariate-modelling-of-faecal-bacterial-profiles-of-patients-with-ibs-predicts-responsiveness-to-a-diet-low-in-fodmaps
#6
Sean M P Bennet, Lena Böhn, Stine Störsrud, Therese Liljebo, Lena Collin, Perjohan Lindfors, Hans Törnblom, Lena Öhman, Magnus Simrén
OBJECTIVE: The effects of dietary interventions on gut bacteria are ambiguous. Following a previous intervention study, we aimed to determine how differing diets impact gut bacteria and if bacterial profiles predict intervention response. DESIGN: Sixty-seven patients with IBS were randomised to traditional IBS (n=34) or low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) (n=33) diets for 4 weeks. Food intake was recorded for 4 days during screening and intervention...
April 17, 2017: Gut
https://www.readbyqxmd.com/read/28395553/proteomics-and-irritable-bowel-syndrome
#7
Athanasios Tsigaridas, Ioannis S Papanikolaou, Anna Vaiopoulou, Athanasios K Anagnostopoulos, Nikos Viazis, George Karamanolis, Dimitrios G Karamanolis, George T Tsangaris, Gerasimos J Mantzaris, Maria Gazouli
Irritable bowel syndrome (IBS) is a gastrointestinal disease that according to Rome IV criteria is subdivided into four subtypes. The pathophysiology of this disease is not well understood due to numerous factors playing multiple roles in disease development, such as diet, stress and hormones. IBS has a variety of symptoms and overlaps with many other gastrointestinal and non-gastrointestinal diseases. Area covered: This review aims to present an overview of implementation of proteomics in experimental studies in the field of IBS...
May 2017: Expert Review of Proteomics
https://www.readbyqxmd.com/read/28346031/chromogranin-a-cell-density-in-the-large-intestine-of-asian-and-european-patients-with-irritable-bowel-syndrome
#8
Magdy El-Salhy, Tanisa Patcharatrakul, Jan Gunnar Hatlebakk, Trygve Hausken, Odd Helge Gilja, Sutep Gonlachanvit
OBJECTIVE: Patients with irritable bowel syndrome (IBS) in Asia show distinctive differences from those in the western world. The gastrointestinal endocrine cells appear to play an important role in the pathophysiology of IBS. The present study aimed at studying the density of chromogranin A (CgA) cells in the large intestine of Thai and Norwegian IBS patients. METHODS: Thirty Thai IBS patients and 20 control subjects, and 47 Norwegian IBS patients and 20 control subjects were included...
June 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28345807/low-fodmap-in-2017-lessons-learned-from-clinical-trials-and-mechanistic-studies
#9
REVIEW
S Eswaran
Given the prevalence of irritable bowel syndrome (IBS) and the suboptimal response to most therapeutic approaches, there has been increasing interest in and adoption of dietary treatment strategies, such as the low Fermentable Oligo-, Di-, & Mono-Saccharides and Polyols (FODMAP) diet. FODMAPs are a diverse group of carbohydrates that exert effects in the gastrointestinal tract not only via fermentation but likely via alterations in the microbiota, metabolome, permeability, and intestinal immunity as well. Clinical evidence for efficacy of this diet is mounting, but there are significant questions regarding short- and long-term safety and effects on the microbiota and nutrition that remain unanswered...
April 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28303579/endometriosis-in-patients-with-irritable-bowel-syndrome-specific-symptomatic-and-demographic-profile-and-response-to-the-low-fodmap-diet
#10
Judith S Moore, Peter R Gibson, Richard E Perry, Rebecca E Burgell
BACKGROUND: Women with endometriosis are frequently misdiagnosed with irritable bowel syndrome (IBS) for some time before a correct diagnosis is made. Visceral hypersensitivity is a key feature in both conditions. AIMS: To determine if there are distinct symptom patterns in women with IBS and endometriosis, and to determine the response of these women to a low FODMAP diet in comparison to those with IBS alone. MATERIALS AND METHODS: A retrospective analysis of prospectively collected data from women attending a specialist IBS service in Christchurch New Zealand...
March 17, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28300773/the-low-fodmap-diet-many-question-marks-for-a-catchy-acronym
#11
REVIEW
Giulia Catassi, Elena Lionetti, Simona Gatti, Carlo Catassi
FODMAP, "Fermentable Oligo-, Di- and Mono-saccharides And Polyols", is a heterogeneous group of highly fermentable but poorly absorbed short-chain carbohydrates and polyols. Dietary FODMAPs might exacerbate intestinal symptoms by increasing small intestinal water volume, colonic gas production, and intestinal motility. In recent years the low-FODMAP diet for treatment of irritable bowel syndrome (IBS) has gained increasing popularity. In the present review we aim to summarize the physiological, clinical, and nutritional issues, suggesting caution in the prolonged use of this dietary treatment on the basis of the existing literature...
March 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28282855/higher-levels-of-serum-zonulin-may-rather-be-associated-with-increased-risk-of-obesity-and-hyperlipidemia-than-with-gastrointestinal-symptoms-or-disease-manifestations
#12
Bodil Ohlsson, Marju Orho-Melander, Peter M Nilsson
Zonulin is considered a biomarker of increased intestinal permeability, and elevated levels have been found in celiac disease. The primary aim of this study was to examine the association between serum zonulin levels and gastrointestinal (GI) symptoms, and secondarily, between zonulin levels and anthropometric and metabolic factors. The offspring (n = 363) of the participants of the Malmö Diet and Cancer cardiovascular cohort (MDC-CV) were invited to an anthropometric and clinical examination, where fasting plasma glucose levels were measured...
March 8, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28244679/use-of-the-low-fodmap-diet-in-inflammatory-bowel-disease
#13
REVIEW
Peter R Gibson
Irritable bowel syndrome (IBS)-like symptoms are not uncommon in patients with quiescent inflammatory bowel disease (IBD). While gluten-free diet is applied by patients, there are no reported interventional studies. The low-FODMAP diet, on the other hand, has efficacy similar to that seen in patients with IBS in three unblinded or observational studies of IBD cohorts who had well-controlled inflammatory disease and in one small randomized cross-over study. FODMAP intake by patients with IBD is not elevated, and, in one study, fructan intakes were lower in patients with Crohn's disease than in controls...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28244677/using-ehealth-strategies-in-delivering-dietary-and-other-therapies-in-patients-with-irritable-bowel-syndrome-and-inflammatory-bowel-disease
#14
REVIEW
Dorit Vedel Ankersen, Katrine Carlsen, Dorte Marker, Pia Munkholm, Johan Burisch
Health-care systems around the world are facing increasing costs. Non-adherent, chronically ill patients are one such expense incurred by health-care providers. Web-based home-monitoring of patients-or eHealth-has been shown to increase adherence to medical therapy, facilitate contact between patients and health-care professionals, and reduce time to remission for patients with inflammatory bowel disease (IBD). Web-based treatment is a supportive tool for the health-care provider in an out-patient clinic. eHealth web-programs, such as the Constant Care application, visualize disease activity in a traffic light system and empower patients to screen for disease activity, enabling them to respond appropriately to their symptoms...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28244673/history-of-the-low-fodmap-diet
#15
REVIEW
Peter R Gibson
It has long been known that many short-chain carbohydrates can induce abdominal symptoms that are similar to those in patients with irritable bowel syndrome (IBS). It was hypothesized that restricting the intake of all short-chain carbohydrates that are either slowly absorbed or not digested in the small intestine should be considered together because they all have similar effects on the intestine by distending the lumen. These groups of carbohydrates were called, Fermentable, Oligosaccharides, Disaccharides and Monosaccharides and Polyols (FODMAPs), because of the lack of a known collective term...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28244671/prebiotic-inulin-type-fructans-and-galacto-oligosaccharides-definition-specificity-function-and-application-in-gastrointestinal-disorders
#16
REVIEW
Bridgette Wilson, Kevin Whelan
Prebiotics are non-digestible selectively fermented dietary fibers that specifically promote the growth of one or more bacterial genera in the gastrointestinal tract and thus provide health benefit to the host. The two most investigated prebiotics being the inulin-type fructans and galacto-oligosaccharides. Prebiotic specificity is mediated through species-specific gene clusters within saccharolytic bacteria controlled by signaling sensors for various substrates. Prebiotic health benefits are attributed to immune regulation and bacterial metabolite production...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28244670/the-low-fodmap-diet-in-the-management-of-functional-dyspepsia-in-east-and-southeast-asia
#17
REVIEW
Victoria P Tan
Functional dyspepsia (FD) is a common disorder in East and Southeast Asia where subjects experience post prandial fullness/bloating, early satiety, belching, epigastric pain, and/or burning. A subset of patients with FD experience triggers exclusively related to meals, defined as the post prandial distress syndrome in the Rome IV guidelines. There is significant overlap of symptoms and implicated pathogenic factors with another common functional gastrointestinal disorder, irritable bowel syndrome (IBS) and in fact, a significant proportion of subjects have FD/IBS overlap...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28244669/how-to-institute-the-low-fodmap-diet
#18
REVIEW
Jacqueline S Barrett
A diet low in poorly absorbed, fermentable, short chain carbohydrates (FODMAPs) is an effective strategy to manage symptoms of irritable bowel syndrome (IBS). The diet has gained traction since its original description in Australia 10 years ago and is now an internationally accepted dietary management strategy for IBS. Randomized controlled trials have raised the profile of the low-FODMAP diet to become a viable first-line therapy for IBS, when implemented under a dietitian's guidance. Importantly, the diagnosis of IBS should be confirmed before commencement of the dietary approach...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28244668/the-evidence-base-for-efficacy-of-the-low-fodmap-diet-in-irritable-bowel-syndrome-is-it-ready-for-prime-time-as-a-first-line-therapy
#19
REVIEW
Peter R Gibson
Six randomized controlled trials comparing low FODMAP diet with placebo approaches have all indicated efficacy in patients with irritable bowel syndrome (IBS). The studies have provided all the food (n = 3) or utilized dietitian-led education (n = 3). They have variably met criticisms regarding issues such as the choice of placebo, the number of patients studied, the success of blinding, and the duration of the interventions, but the results are uniformly positive for the diet. Real-world experience of the low FODMAP diet has confirmed the findings of the randomized studies, in that about 70% of patients respond...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28244666/when-the-low-fodmap-diet-does-not-work
#20
REVIEW
Emma P Halmos
Irritable bowel syndrome (IBS) is heterogeneous. Patients need proper assessment and explanation of IBS pathophysiology and appropriate therapies. A low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) diet effectively reduces symptoms in 75% of patients. Best treatment for those nonresponsive will depend on the pathophysiological basis for symptom genesis, with the following possible abnormalities: (i) Visceral hypersensitivity and/or enhanced gut-brain communication: a low FODMAP diet is mainly targeted for this patient group...
March 2017: Journal of Gastroenterology and Hepatology
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