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IBS and diet

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https://www.readbyqxmd.com/read/29651299/a-leukocyte-activation-test-identifies-food-items-which-induce-release-of-dna-by-innate-immune-peripheral-blood-leucocytes
#1
Irma Garcia-Martinez, Theresa R Weiss, Muhammad N Yousaf, Ather Ali, Wajahat Z Mehal
Background: Leukocyte activation (LA) testing identifies food items that induce a patient specific cellular response in the immune system, and has recently been shown in a randomized double blinded prospective study to reduce symptoms in patients with irritable bowel syndrome (IBS). We hypothesized that test reactivity to particular food items, and the systemic immune response initiated by these food items, is due to the release of cellular DNA from blood immune cells. Methods: We tested this by quantifying total DNA concentration in the cellular supernatant of immune cells exposed to positive and negative foods from 20 healthy volunteers...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29605976/clinical-practice-guidelines-for-irritable-bowel-syndrome-in-korea-2017-revised-edition
#2
REVIEW
Kyung Ho Song, Hye-Kyung Jung, Hyun Jin Kim, Hoon Sup Koo, Yong Hwan Kwon, Hyun Duk Shin, Hyun Chul Lim, Jeong Eun Shin, Sung Eun Kim, Dae Hyeon Cho, Jeong Hwan Kim, Hyun Jung Kim
In 2011, the Korean Society of Neurogastroenterology and Motility (KSNM) published clinical practice guidelines on the management of irritable bowel syndrome (IBS) based on a systematic review of the literature. The KSNM planned to update the clinical practice guidelines to support primary physicians, reduce the socioeconomic burden of IBS, and reflect advances in the pathophysiology and management of IBS. The present revised version of the guidelines is in continuity with the previous version and targets adults diagnosed with, or suspected to have, IBS...
April 30, 2018: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/29568206/low-fodmap-vs-regular-rye-bread-in-irritable-bowel-syndrome-randomized-smartpill-%C3%A2-study
#3
Laura Pirkola, Reijo Laatikainen, Jussi Loponen, Sanna-Maria Hongisto, Markku Hillilä, Anu Nuora, Baoru Yang, Kaisa M Linderborg, Riitta Freese
AIM: To compare the effects of regular vs low-FODMAP rye bread on irritable bowel syndrome (IBS) symptoms and to study gastrointestinal conditions with SmartPill® . METHODS: Our aim was to evaluate if rye bread low in FODMAPs would cause reduced hydrogen excretion, lower intraluminal pressure, higher colonic pH, different transit times, and fewer IBS symptoms than regular rye bread. The study was a randomized, double-blind, controlled cross-over meal study. Female IBS patients ( n = 7) ate study breads at three consecutive meals during one day...
March 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29503786/a-mexican-honeymoon-marred-by-gastrointestinal-upset-a-case-of-dientamoeba-fragilis-causing-post-infectious-irritable-bowel-syndrome
#4
Saeed Ali, Neelam Khetpal, Muhammad Talha Khan, Mamoon Rasheed, Fnu Asad-Ur-Rahman, Karen Echeverria-Beltran
Dientamoeba fragilis (D. fragilis) is an anaerobic intestinal protozoan parasite that has been associated with irritable bowel syndrome (IBS)-like symptoms. We report a case of post-infectious IBS caused by D. fragilis treated successfully with metronidazole. A 33-year-old African American male with an unremarkable past medical history was seen in the office with a three-month history of intermittent, generalized, crampy abdominal pain with bloating and flatulence without associated weight loss. He visited Mexico for his honeymoon four months ago...
December 27, 2017: Curēus
https://www.readbyqxmd.com/read/29498019/a-review-of-microbiota-and-irritable-bowel-syndrome-future-in-therapies
#5
REVIEW
Bruno K Rodiño-Janeiro, María Vicario, Carmen Alonso-Cotoner, Roberto Pascua-García, Javier Santos
Irritable bowel syndrome (IBS), one of the most frequent digestive disorders, is characterized by chronic and recurrent abdominal pain and altered bowel habit. The origin seems to be multifactorial and is still not well defined for the different subtypes. Genetic, epigenetic and sex-related modifications of the functioning of the nervous and immune-endocrine supersystems and regulation of brain-gut physiology and bile acid production and absorption are certainly involved. Acquired predisposition may act in conjunction with infectious, toxic, dietary and life event-related factors to enhance epithelial permeability and elicit mucosal microinflammation, immune activation and dysbiosis...
March 1, 2018: Advances in Therapy
https://www.readbyqxmd.com/read/29497906/adherence-to-a-low-fodmap-diet-in-relation-to-symptoms-of-irritable-bowel-syndrome-in-iranian-adults
#6
Helia Pourmand, Ammar Hassanzadeh Keshteli, Parvane Saneei, Hamed Daghaghzadeh, Ahmad Esmaillzadeh, Peyman Adibi
BACKGROUND: Most studies assessing the influence of a low fermentable oligo-, di-, monosaccharides and polyols (FODMAP) diet on irritable bowel syndrome (IBS) symptoms were clinical trials with a small sample size. OBJECTIVE: This study was done to examine the association between adherence to a low FODMAP diet and symptoms of irritable bowel syndrome in Iranian adults. METHODS: In this cross-sectional study, data on 3362 Iranian adults were collected...
March 1, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29459596/irritable-bowel-syndrome-prevalence-and-dietary-factors-in-the-sylhet-district-of-bangladesh
#7
M Saha, I Parveen, M S Uddoula, M J Alam, N S Afsar, B C Debnath, S E Ali
Irritable bowel syndrome (IBS) is a common functional bowel disorder. Along with other factors diet plays an important role in the causation of IBS. This population-based study was done to find out the prevalence of IBS and to find out the dietary factors associated with IBS from August 2011 to December 2011 in Sylhet district of Bangladesh. Nineteen hundred apparently healthy subjects selected by cluster sampling methods were interviewed by a validated bowel disease questionnaire. Dietary history of the subjects was also taken...
January 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29451364/the-prevalence-of-celiac-disease-in-adult-chinese-patients-with-diarrhea-predominant-irritable-bowel-syndrome-of-china-a-prospective-controlled-cohort-study
#8
Guanjun Kou, Jing Guo, Xiuli Zuo, Changqing Li, Chao Liu, Rui Ji, Han Liu, Xiao Wang, Yanqing Li
BACKGROUND: Celiac disease (CD) is a chronic inflammatory enteropathy with a symptom spectrum similar to that of irritable bowel syndrome (IBS). CD is a common, but largely undiagnosed, condition in Western countries. However, it is extremely rare among Chinese people, and few studies have evaluated its prevalence in China. OBJECTIVE: To determine the prevalence of CD in IBS patients diagnosed using the Rome III criteria in North China. METHODS: This was a single-center, prospective, controlled cohort study performed in Qilu Hospital involving 246 IBS patients and 246 healthy controls...
February 16, 2018: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29421808/pathophysiology-of-functional-gastrointestinal-disorders-a-holistic-overview
#9
Gerald Holtmann, Ayesha Shah, Mark Morrison
Background and Summary: Traditionally, functional gastrointestinal disorders (FGID), including functional dyspepsia or irritable bowel syndrome (IBS), are defined by more or less specific symptoms and the absence of structural or biochemical abnormalities that cause these symptoms. This concept is now considered to be outdated; if appropriate tests are applied, structural or biochemical abnormalities that explain or cause the symptoms may be found in many patients. Another feature of FGID are the highly prevalent psychiatric comorbidities, such as depression and anxiety...
2017: Digestive Diseases
https://www.readbyqxmd.com/read/29413008/the-role-of-diet-in-the-treatment-of-irritable-bowel-syndrome-a-systematic-review
#10
REVIEW
Rajdeep Singh, Ahmed Salem, Julie Nanavati, Gerard E Mullin
Irritable bowel syndrome (IBS) is a multifaceted illness involving maladaptive shifts in the gut microbiota that affect the enteric nervous and immune systems, mucosal barrier function, the balance of neurotransmitters and hormones, and emotional well-being. There is abundant evidence indicating that certain foods elicit symptoms in IBS. Numerous elimination-type diets have been shown to alleviate symptoms. However, among these, the most controversial is a group of foods called fructo, oligo-, di-, and monosaccharides and polyols (FODMAPs)...
March 2018: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29399039/food-consumption-and-dietary-intakes-in-36-448-adults-and-their-association-with-irritable-bowel-syndrome-nutrinet-sant%C3%A3-study
#11
Marion J Torres, Jean-Marc Sabate, Michel Bouchoucha, Camille Buscail, Serge Hercberg, Chantal Julia
Introduction: Diet plays an important role for patients with irritable bowel syndrome (IBS). The aim of this study was to compare the diets in terms of food consumption and nutrient intake between subjects with IBS and controls in a large French population. Methods: This study included 36,448 subjects from the Nutrinet-Santé cohort study, who completed a questionnaire pertaining to functional bowel disorders based on the Rome III criteria. Dietary data were obtained from at least three self-administered 24 h records via the internet...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29373532/the-role-of-bacteria-probiotics-and-diet-in-irritable-bowel-syndrome
#12
REVIEW
Ashton Harper, Malwina M Naghibi, Davinder Garcha
Irritable bowel syndrome is a highly prevalent gastrointestinal disorder that threatens the quality of life of millions and poses a substantial financial burden on healthcare systems around the world. Intense research into the human microbiome has led to fascinating discoveries which directly and indirectly implicate the diversity and function of this occult organ in irritable bowel syndrome (IBS) pathophysiology. The benefit of manipulating the gastrointestinal microbiota with diet and probiotics to improve symptoms has been demonstrated in a wealth of both animal and human studies...
January 26, 2018: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/29336079/the-low-fodmap-diet-in-the-management-of-irritable-bowel-syndrome-an-evidence-based-review-of-fodmap-restriction-reintroduction-and-personalisation-in-clinical-practice
#13
K Whelan, L D Martin, H M Staudacher, M C E Lomer
Dietary restriction of fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) is effective in the management of functional gastrointestinal symptoms that occur in irritable bowel syndrome (IBS). Numerous reviews have been published regarding the evidence for their restriction in the low FODMAP diet; however, few reviews discuss the implementation of the low FODMAP diet in practice. The aim of this review is to provide practical guidance on patient assessment and the implementation and monitoring of the low FODMAP diet...
April 2018: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29302878/exploring-gut-microbiota-composition-as-an-indicator-of-clinical-response-to-dietary-fodmap-restriction-in-patients-with-irritable-bowel-syndrome
#14
Jørgen Valeur, Milada Cvancarova Småstuen, Torunn Knudsen, Gülen Arslan Lied, Arne Gustav Røseth
BACKGROUND: A diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) may relieve symptoms of irritable bowel syndrome (IBS). However, nutritional counseling is resource-demanding and not all patients will benefit. AIMS: To explore whether gut microbial composition may identify symptom response to a low-FODMAP diet in patients with IBS. METHODS: Patients were recruited consecutively to participate in a 4-week FODMAP-restricted diet...
February 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29300051/ibs-high-fodmap-diet-induces-lps-derived-intestinal-inflammation-and-visceral-hypersensitivity
#15
Iain Dickson
No abstract text is available yet for this article.
February 2018: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29206754/abdominal-ultrasound-does-not-reveal-significant-alterations-in-patients-with-nonceliac-wheat-sensitivity
#16
Maurizio Soresi, Pasquale Mansueto, Antonino Terranova, Alberto D'Alcamo, Francesco La Blasca, Francesca Cavataio, Rosario Iacobucci, Antonio Carroccio
GOALS: The goal of this study was (A) to evaluate abdominal ultrasound signs in nonceliac wheat sensitivity (NCWS) patients for features useful in diagnosis and (B) to compare these aspects with those of celiac patients to assess whether ultrasound can be useful in the differential diagnosis between NCWS and celiac disease (CD). BACKGROUND: NCWS diagnosis is difficult as no biomarkers of this condition have as yet been identified. In CD ultrasound aspects have been identified that have a good diagnostic accuracy...
December 4, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29202473/fodmap-diet-modulates-visceral-nociception-by-lipopolysaccharide-mediated-intestinal-inflammation-and-barrier-dysfunction
#17
Shi-Yi Zhou, Merritt Gillilland, Xiaoyin Wu, Pornchai Leelasinjaroen, Guanpo Zhang, Hui Zhou, Bo Ye, Yuanxu Lu, Chung Owyang
Foods high in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) exacerbate symptoms of irritable bowel syndrome (IBS); however, their mechanism of action is unknown. We hypothesized that a high-FODMAP (HFM) diet increases visceral nociception by inducing dysbiosis and that the FODMAP-altered gut microbial community leads to intestinal pathology. We fed rats an HFM and showed that HFM increases rat fecal Gram-negative bacteria, elevates lipopolysaccharides (LPS), and induces intestinal pathology, as indicated by inflammation, barrier dysfunction, and visceral hypersensitivity (VH)...
January 2, 2018: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29159993/low-fodmaps-diet-vs-general-dietary-advice-improves-clinical-response-in-patients-with-diarrhea-predominant-irritable-bowel-syndrome-a-randomized-controlled-trial
#18
Mohammad Javad Zahedi, Vahideh Behrouz, Maryam Azimi
BACKGROUND AND AIMS: Recent evidence indicates that new approach of the diet with low Fermentable Oligo-Di-Mono-saccharides and polyols (FODMAPs) may has an effective role in management of the patients with irritable bowel syndrome (IBS). We compared the results of low FODMAP diet vs. current dietary treatment, general dietary advices (GDA), on the clinical response in patients with diarrhea subtype of IBS (IBS-D). METHODS: In this randomized, controlled, single-blind trial, we included 110 patients with IBS-D in 2 intervention groups...
November 20, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29156449/nutrition-in-the-management-of-gastrointestinal-diseases-and-disorders-the-evidence-for-the-low-fodmap-diet
#19
REVIEW
Shanti Eswaran, Jeremy P Farida, Jessica Green, Jesse D Miller, William D Chey
A growing interest from both physicians and patients is fueling research in the interaction of symptoms related to irritable bowel syndrome (IBS) and diet, particularly the low FODMAP diet. Recent studies further define the role of these short-chain fermentable carbohydrates on IBS symptoms and their effects in different parts of the gastrointestinal tract. Mounting evidence supports the use of a low FODMAP diet in the clinical setting, but this dietary approach is not without potential drawbacks. This review illustrates the mechanisms by which the low FODMAP diet leads to improvement in IBS symptoms, summarizes the available clinical evidence, and offers practical advice regarding implementation of this dietary strategy...
December 2017: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29152407/fecal-microbiota-transplantation-against-irritable-bowel-syndrome-rigorous-randomized-clinical-trials-are-required
#20
Amin Talebi Bezmin Abadi
Halkjær et al searched systematically nine articles including 48 patients, and concluded that fecal microbiota transplantation (FMT) can be an ideal treatment option for irritable bowel syndrome (IBS) subjects. Regardless of the few successes in current traditional therapies (change in diet, herbal medicine and antibiotics) in IBS, a sharp increase in interests in the FMT option has been reported in the current century. However, there is a long list of unclear issues concerning the application of FMT for the treatment of IBS...
November 6, 2017: World Journal of Gastrointestinal Pharmacology and Therapeutics
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