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Diet and gout

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https://www.readbyqxmd.com/read/28975090/chronic-dietary-oxalate-nephropathy-after-intensive-dietary-weight-loss-regimen
#1
Gebran Khneizer, Ahmad Al-Taee, Meher S Mallick, Bahar Bastani
BACKGROUND: Hyperoxaluria has been associated with nephrolithiasis as well as acute and chronic kidney disease. We present a case of end stage renal failure caused by excessive dietary oxalate intake in a dietary weight loss regimen. CASE PRESENTATION: A 51-year-old Caucasian male with the past medical history of type 2 diabetes mellitus, gout, hypertension and morbid obesity was referred to the primary care clinic after being found pale and easily fatigued. The patient had lost 36 kg over a 7-month period by implementing exercise and intense dietary measures that included 6 meals of spinach, kale, berries, and nuts...
July 2017: Journal of Nephropathology
https://www.readbyqxmd.com/read/28915838/gout-and-comorbidity-a-nominal-group-study-of-people-with-gout
#2
Jasvinder A Singh
BACKGROUND: Comorbidities are common in patients with gout, yet qualitative research is lacking. The study objective was to examine the impact of gout on comorbidities. METHODS: Nine nominal groups were conducted. Patients with gout discussed and rank-ordered their concerns in response to the question, "How does gout or its treatment affect your other conditions and their treatment?" RESULTS: Nine nominal groups had 45 gout patients, with mean age 61 years (standard deviation (SD) 10...
September 15, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28866649/weight-loss-for-overweight-and-obese-individuals-with-gout-a-systematic-review-of-longitudinal-studies
#3
Sabrina M Nielsen, Else M Bartels, Marius Henriksen, Eva E Wæhrens, Henrik Gudbergsen, Henning Bliddal, Arne Astrup, Filip K Knop, Loreto Carmona, William J Taylor, Jasvinder A Singh, Fernando Perez-Ruiz, Lars E Kristensen, Robin Christensen
OBJECTIVES: Weight loss is commonly recommended for gout, but the magnitude of the effect has not been evaluated in a systematic review. The aim of this systematic review was to determine benefits and harms associated with weight loss in overweight and obese patients with gout. METHODS: We searched six databases for longitudinal studies, reporting the effect of weight loss in overweight/obese gout patients. Risk of bias was assessed using the tool Risk of Bias in Non-Randomised Studies of Interventions...
November 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28836797/an-illness-by-any-other-name-the-effect-of-renaming-gout-on-illness-and-treatment-perceptions
#4
Keith J Petrie, Kate MacKrill, Christina Derksen, Nicola Dalbeth
OBJECTIVE: Inaccurate lay views of an illness can lead to the adoption of unhelpful coping strategies and treatments. Gout is an example of an illness where the popular view of the condition conflicts with a modern understanding of the illness by overemphasizing the role of diet and alcohol in the development and management of the disease. In this study we investigated the effect of renaming gout as urate crystal arthritis on the perceptions of the illness. METHOD: One-hundred and 89 supermarket shoppers participated in a study examining the perceptions of different types of arthritis...
August 24, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28818081/what-makes-gouty-inflammation-so-variable
#5
REVIEW
Robert Terkeltaub
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem. Flares can be complex and expensive to treat, partly due to the frequent comorbidities. Unmet needs in gout management are more pressing given the markedly increasing gout flare hospital admission rates. In addition, chronic gouty arthritis can cause joint damage and functional impairment. This review addresses new knowledge on the basis for the marked, inherent variability of responses to deposited urate crystals, including the unpredictable and self-limited aspects of many gout flares...
August 18, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28748117/epidemiology-pathophysiology-and-management-of-uric-acid-urolithiasis-a-narrative-review
#6
REVIEW
A Abou-Elela
An in-depth comprehension of the epidemiology as well as pathophysiology of uric acid urolithiasis is important for the identification, treatment, and prophylaxis of calculi in these patients. Persistently low urinary pH, hyperuricosuria, and low urinary volume are the most important factors in pathogenesis of uric acid urolithiasis. Other various causes of calculus formation comprises of chronic diarrhea, renal hyperuricosuria, insulin resistance, primary gout, extra purine in the diet, neoplastic syndromes, and congenital hyperuricemia...
September 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28748116/gout-an-old-disease-in-new-perspective-a-review
#7
REVIEW
Gaafar Ragab, Mohsen Elshahaly, Thomas Bardin
Gout is a picturesque presentation of uric acid disturbance. It is the most well understood and described type of arthritis. Its epidemiology is studied. New insights into the pathophysiology of hyperuricemia and gouty arthritis; acute and chronic allow for an even better understanding of the disease. The role of genetic predisposition is becoming more evident. The clinical picture of gout is divided into asymptomatic hyperuricemia, acute gouty arthritis, intercritical period, and chronic tophaceous gout. Diagnosis is based on laboratory and radiological features...
September 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/28745686/-effects-of-keto-amino-acids-and-a-low-protein-diet-on-the-nutritional-status-of-patients-with-stages-3b-4-chronic-kidney-disease
#8
S Yu Milovanova, Yu S Milovanov, M V Taranova, I A Dobrosmyslov
AIM: To evaluate the efficacy of keto/amino acids in maintaining protein balance and preventing mineral metabolic disturbances and the development of uremic hyperparathyroidism in the long-term use of a low-protein diet (LPD) in patients with Stages 3B-4 chronic kidney disease (CKD). SUBJECTS AND METHODS: Ninety patients with CKD caused by chronic latent glomerulonephritis in 65 patients and chronic tubulointerstitial nephritis of various etiologies (gout, drug-induced, and infection) in 25 were examined...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28490548/diet-high-in-vegetables-fruit-and-whole-grains-may-reduce-risk-of-gout
#9
Susan Mayor
No abstract text is available yet for this article.
May 9, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28487277/the-dietary-approaches-to-stop-hypertension-dash-diet-western-diet-and-risk-of-gout-in-men-prospective-cohort-study
#10
Sharan K Rai, Teresa T Fung, Na Lu, Sarah F Keller, Gary C Curhan, Hyon K Choi
Objective To prospectively examine the relation between the Dietary Approaches to Stop Hypertension (DASH) and Western diets and risk of gout (ie, the clinical endpoint of hyperuricemia) in men.Design Prospective cohort study.Setting The Health Professionals Follow-up Study.Participants 44 444 men with no history of gout at baseline. Using validated food frequency questionnaires, each participant was assigned a DASH dietary pattern score (based on high intake of fruits, vegetables, nuts and legumes, low fat dairy products, and whole grains, and low intake of sodium, sweetened beverages, and red and processed meats) and a Western dietary pattern score (based on high intake of red and processed meats, French fries, refined grains, sweets, and desserts)...
May 9, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28464485/education-preferences-of-people-with-gout-exploring-differences-between-indigenous-and-non-indigenous-peoples-from-rural-and-urban-locations
#11
Gareth J Treharne, Aimee C Richardson, Tia Neha, Niamh Fanning, Ronald Janes, Ben Hudson, Andrea Judd, Suzanne Pitama, Lisa K Stamp
OBJECTIVES: Gout typically responds well to medications but adherence might be improved by education that meets individuals' needs in a way that is inclusive of their ethnicity and rurality. The aim of this study was to compare educational preferences of: 1) Māori and New Zealand European (NZEuropean) individuals with gout; and 2) those living in rural or urban areas. METHODS: People with gout managed in primary care were recruited from two rural regions and one city within Aotearoa/New Zealand...
May 2, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28457529/fructose-malabsorption-in-people-with-and-without-gout-a-case-control-study
#12
Caitlin Batt, Niamh Fanning, Jill Drake, Christopher Frampton, Richard B Gearry, Lisa K Stamp
BACKGROUND: Higher fructose intake has been associated with hyperuricaemia and gout. Some individuals malabsorb fructose in the small intestine. The aims of this study were to determine the rate of fructose malabsorption and the effects of gout and fructose malabsorption on serum urate in people with and without gout. METHODS: A total of 100 people with gout (cases) were age and gender matched with one control without gout. After a low fructose diet, fructose malabsorption was measured using a hydrogen and methane breath test with a 35g fructose load...
March 22, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28440522/-nutrition-management-in-obese-patients-with-type-2-diabetes-mellitus-after-laparoscopic-sleeve-gastrectomy
#13
Weihong Tang, Yuhua Chen, Meizhen Pan, Lihua Chen, Lele Zhang, Tingfeng Wang, Xiong Zhang, Peng Zhang, Chengzhu Zheng, Bo Yu
OBJECTIVE: To explore the value of nutrition management in obese patients with type 2 diabetes mellitus(T2DM) after laparoscopic sleeve gastrectomy(LSG). METHODS: Clinical data of 22 obese T2DM patients undergoing LSG from March 2013 to July 2015 in Fudan University Pudong Medical Center were collected. All the patients strictly followed the specialized instruction by nutritionists: diabetic and low calorie diet 3347.2 to 5020.8 kJ (800 to 1200 kcal) per day before the operation; low calorie liquid diet 2510...
April 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28430170/current-management-of-gout-practical-messages-from-2016-eular-guidelines
#14
George Nuki, Michael Doherty, Pascal Richette
The European League Against Rheumatism published updated recommendations for the management of gout in 2016, comprising 3 overarching principles and 11 key recommendations for clinical practice. Patient education about the pathophysiology of gout and its comorbidities, as well as the existence of effective treatments are important, and understanding the principles of managing acute attacks and eliminating urate crystals by lifelong lowering of the serum urate (SU) below a target level are essential. Advice about lifestyle, diet, weight, and other risk factors, as well as the need to screen for, and manage, comorbidities is emphasized...
April 28, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28345493/genetic-risk-scores-sex-and-dietary-factors-interact-to-alter-serum-uric-acid-trajectory-among-african-american-urban-adults
#15
May A Beydoun, Jose-Atilio Canas, Marie T Fanelli-Kuczmarski, Salman M Tajuddin, Michele K Evans, Alan B Zonderman
Serum uric acid (SUA), a causative agent for gout among others, is affected by both genetic and dietary factors, perhaps differentially by sex. We evaluated cross-sectional (SUAbase) and longitudinal (SUArate) associations of SUA with a genetic risk score (GRS), diet and sex. We then tested the interactive effect of GRS, diet and sex on SUA. Longitudinal data on 766 African-American urban adults participating in the Healthy Aging in Neighborhood of Diversity across the Lifespan study were used. In all, three GRS for SUA were created from known SUA-associated SNP (GRSbase (n 12 SNP), GRSrate (n 3 SNP) and GRStotal (n 15 SNP))...
March 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28249154/%C3%AE-hydroxybutyrate-deactivates-neutrophil-nlrp3-inflammasome-to-relieve-gout-flares
#16
Emily L Goldberg, Jennifer L Asher, Ryan D Molony, Albert C Shaw, Caroline J Zeiss, Chao Wang, Ludmilla A Morozova-Roche, Raimund I Herzog, Akiko Iwasaki, Vishwa Deep Dixit
Aging and lipotoxicity are two major risk factors for gout that are linked by the activation of the NLRP3 inflammasome. Neutrophil-mediated production of interleukin-1β (IL-1β) drives gouty flares that cause joint destruction, intense pain, and fever. However, metabolites that impact neutrophil inflammasome remain unknown. Here, we identified that ketogenic diet (KD) increases β-hydroxybutyrate (BHB) and alleviates urate crystal-induced gout without impairing immune defense against bacterial infection. BHB inhibited NLRP3 inflammasome in S100A9 fibril-primed and urate crystal-activated macrophages, which serve to recruit inflammatory neutrophils in joints...
February 28, 2017: Cell Reports
https://www.readbyqxmd.com/read/28238670/association-of-pregnancy-with-stone-formation-among-women-in-the-united-states-a-nhanes-analysis-2007-to-2012
#17
Lael Reinstatler, Sari Khaleel, Vernon M Pais
PURPOSE: Lithogenic urinary changes develop during pregnancy. Such changes may increase stone proclivity thereafter in working and child rearing aged women. However, to our knowledge such an association has not been previously identified. MATERIALS AND METHODS: We analyzed nationally representative data from the 2007 to 2012 NHANES (National Health and Nutrition Examination Survey) to assess the association between pregnancy and nephrolithiasis. RESULTS: The weighted national prevalence of nephrolithiasis among women 50 years or younger was 6...
February 24, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28223818/an-evidence-based-review-on-urate-lowering-treatments-implications-for-optimal-treatment-of-chronic-hyperuricemia
#18
REVIEW
Marilisa Bove, Arrigo Francesco Giuseppe Cicero, Maddalena Veronesi, Claudio Borghi
Several studies suggest that chronic hyperuricemia, the main precursor of gout, is involved in the pathogenesis of different systemic disorders that affect cardiovascular and renal systems, such as hypertension, obesity, hypercholesterolemia, atherosclerosis, metabolic syndrome, chronic heart failure, and chronic kidney disease. Recent epidemiological evidence has shown an increasing trend in the prevalence of hyperuricemia and gout in the Western world: a number of population-based studies estimate a prevalence of up to 21% for hyperuricemia and 1%-4% for gout...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/28163851/a-systematic-review-of-the-relationship-between-dystemprament-sue-mizaj-and-treatments-and-management-of-diseases-ilaj-and-eslah-e-mizaj
#19
REVIEW
Sepide Miraj, Samira Alesaeidi, Sara Kiani
BACKGROUND: Temperament refers to four different humors differentiating in individuals and, as a result, proposes specific therapy for diseases as well as special types of management (avoidance). OBJECTIVE: The aim of this study was to overview the relationship between dystemprament and treatment and management of diseases. METHODS: A computerized search of published articles was performed using PubMed, Scopus, Web of Science, and Medline databases as well as local sources from 1965 to 2016...
December 2016: Electronic Physician
https://www.readbyqxmd.com/read/28118526/gout-self-management-in-african-american-veterans-a-qualitative-exploration-of-challenges-and-solutions-from-patients-perspectives
#20
Jasvinder A Singh, Ivan Herbey, Aseem Bharat, Janet E Dinnella, Sally Pullman-Mooar, Seth Eisen, Nataliya Ivankova
OBJECTIVE: To explore gout self-management and associated challenges and solutions in African Americans. METHODS: We conducted semistructured interviews with 35 African American veterans with gout, who received health care at Birmingham or Philadelphia Veterans Affairs (VA) medical centers, had filled urate-lowering therapy (ULT; most commonly allopurinol) for at least 6 months, and had a ULT medication possession ratio ≥80%. The interview protocol was constructed to explore key concepts related to gout self-management, including initial diagnosis of gout, beginning medical care for gout, the course of the gout, ULT medication adherence, dietary strategies, comorbidity and side effects, and social support...
January 24, 2017: Arthritis Care & Research
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